Laboratory
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | no effect | fertility and hatchability of eggs, and duckling survival to 14 days | Not Reported | Juvenile | 24 pairs/dose | Toxicity Factor Datasets | 7 and 11 months old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DICROTOPHOS, FENTHION | 68-78% | maximal brain acetylcholinesterase activity inhibition compared to control (after 3 days treatmentt) | Not Reported | Juvenile | 4/group | Toxicity Factor Datasets | 1 day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLPARATHION | 2/12 when treatment initiated during early incub.; 2/11 when treatment initiated during late incub. | incidence of adult mortality during incubation compared with controls | Female | Adult | 12 pairs/group | Toxicity Factor Datasets | 7 mo | Laboratory | |
METHYLPARATHION | increased when treatment initiated during early or late incub. | incidence of nest abandonment compared with controls | Female | Adult | 12 pairs/group | Toxicity Factor Datasets | 7 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
MALATHION | decreased @ 125 (aqueous), 14.0 (oil) lb/acre | embryo weight by day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
DIAZINON, MALATHION, PARATHION | decreased @ all doses | brain or plasma cholinesterase activity in embryos or hatchlings compared to controls | Not Reported | Embryo, Hatchling | 12/group | Toxicity Factor Datasets | Day 3 of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EPN | decreased @ 90, 270 ppm | food consumption and body weight compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
EPN | increased @ all doses | incidence of hyperactivity, ataxia, and/or paralysis compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), DDT (4,4'-) | see citation | figure of eggshell thickness over 30 d period (significant differences noted at various times) | Female | Adult | 20/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase @ 0.025 - 5% | pathological release of ornithine carbamyltransferase from kidney | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory | |
CRUDE OILS | increase @ 5% | incidence of degeneration of kidney tubules | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | California Counties | Lab |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased @ 931,000 shot/acre or 2 #four pellets | spleen weight and total white blood cell counts versus controls | Both Male and Female | Adult | 12 (control); 16 (lab); 63 (field) | Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | Laboratory |
LEAD (elemental) | ppm wet wt: 3.47 (1.38), blood; 32.16 (11.60), liver; 114.78 (28.96), femur @ 2 #four shot | mean (2SE) lead concentration in liver, femur and blood | Male | Adult | 11 birds | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EPN | decreased @ 108 ug/g | brain protein content versus controls | Not Reported | Embryo | 10/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory | |
EPN | decreased @ 36 (cholineserase only), 108 ug/g | plasma alkaline phosphatase, aspartate aminotransferase, cholinesterase activities, and uric acid | Not Reported | Embryo | 12/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | lead only: 0.49 (+/-0.10); lead-iron: 0.23 (+/- 0.04) ppm, wet wt | lead concentration in blood (mean +/- SE) | Male | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
LEAD (elemental) | lead only: 3.53 (+/- 1.43); lead-iron: 1.42 (+/- 0.65) ppm, wet wt | lead concentration in kidneys (mean +/- SE) | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
XYLENE | no effect | embryo survival, size, and incidence of abnormalities through incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | 3 or 8 days of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), LEAD COMPOUNDS, MERCURY COMPOUNDS | decreased with both treatments | eggshell thickness versus controls | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 78.2 (carcass); 61.6 (egg); 4.1 (brain) ppm, wet wt | DDE residues in whole carcass, egg contents, and brain | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM, SELENOMETHIONINE | increased @ 60 ppm Se | incidence of ducklings with histopathological lesions versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | 1 d | Laboratory | |
ARSENATE, SODIUM, SELENOMETHIONINE | decreased @ 60 ppm Se, 200 ppm As | growth rate of body weight versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ALUMINUM SULFATE | see table | Ca, Al, P concentrations in femur for different treatments after 2 and 10 wks of treatment | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | Laboratory | |
ALUMINUM SULFATE | decreased on LL and LH diets | femur mass and mean breaking force (LL, LH vs. NN diets) after 2 wks of treatment | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | decreased @ all doses (by 60 d of age) | weight:length of humerus | Female | Juvenile | 36 birds/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
NICKEL SULFATE | no effect | organ wt:body wt ratios | Both Male and Female | Juvenile | 36 birds/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | increased @ 0.5, 3 ppm | changes in avoidance behavior (frightening stimulus) | Not Reported | Juvenile | 319 (control); 339 (0.5 ppm); 158 (3 ppm) | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | decreased @ 30 ppm as Se-met or yeast, or 15 ppm as wheat | food consumption compared to controls | Not Reported | Juvenile | 25 birds/group | Toxicity Factor Datasets | 1 day | Laboratory | |
SELENIUM COMPOUNDS, SELENOMETHIONINE | decreased @ 30 ppm as Se-met or yeast | body weight compared to controls | Not Reported | Juvenile | 25 birds/group | Toxicity Factor Datasets | 1 day | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased @ 40 ppm (25%) | mortality compared to controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
SELENITE, SODIUM | increased @ 40 ppm (12.5%) | mortality compared to controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | 0.10 (@ 0 ppm), 10.13 (@ 5 ppm), 16.25 (@ 10 ppm), 42.21 (@ 20 ppm) ppm, wet wt | mean Cd concentrations in liver by 12 wks of treatment | Not Reported | Juvenile | 12 birds per timexdose treatment | day old | Toxicity Factor Datasets | Laboratory |
CADMIUM CHLORIDE | no effect | body weight, liver weight, and femur density compared to controls | Not Reported | Juvenile | 12 birds per timexdose treatment | day old | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | decreased @ 15 ppm Se (with or w/out B), and 1000 ppm B | hematocrits and hemoglobin concentrations versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
BORIC ACID, SELENOMETHIONINE | 10.8 (@ 15 ppm Se), 56.0 (@ 60 ppm) ppm Se, wet wt 11.0 (@ 1000 ppm B) ppm B, wet wt |
geometric mean Se and B concentrations in liver | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | ppm, wet wt: 0.79-0.86 (egg); 0.89-1.62 (liver); 1.52-1.82 (kidney); 9.03-11.17 (primary feathers); 0.67-0.83 (breast muscle); 0.44-0.59 (brain); 0.51-0.65 (ovary) | mean concentration of Hg in tissues (ranges are for 3 generations) | Female | Adult | 3-14 birds/tissue x generation group | Toxicity Factor Datasets | Laboratory | |
METHYLMERCURY DICYANDIAMIDE | no effect | body weight versus controls | Both Male and Female | Adult | 14 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CRUDE OILS | increased with light, moderate and heavy oiling | thermal conductance of feathers and body heat loss versus controls | Both Male and Female | Adult | 3 birds/treatment | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | plasma calcium concentration | Female | Adult | Not Reported | Toxicity Factor Datasets | 1 yr | Laboratory | |
DDE (4,4'-) | 25% decrease @ 40 mg/kg | calcium content of secreted fluid in the shell gland, compared to control | Female | Adult | 5/dose | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID | decrease @ 1600 ppm | hematocrit and hemoglobin concentration, compared to controls | Both Male and Female | Juvenile | 10 animals/pen; 3 pens/dose | Toxicity Factor Datasets | 1 d | Laboratory | |
BORIC ACID | increase @ 100, 400, 1600 ppm | plasma triglyceride concentration (21-42% increase, compared to controls) | Both Male and Female | Juvenile | 10 animals/pen; 3 pens/dose | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
FUEL OILS | decrease @ 4.0, 7.0, 12.0 ml/kg/d | mean spleen index (spleen wt./body wt.) | Male | Adult | 4-5/dose | Toxicity Factor Datasets | Laboratory | |
COREXIT 9527 | no effect | % mortality, compared to controls | Male | Adult | 6/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease | egg hatchability (# eggs hatching/# fertile eggs), compared to controls | Female | Adult | 20 hens/dose | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | no effect | onset of laying, egg production, egg fertility and egg hatchability, compared to controls | Female | Adult | 20 hens/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PHOSPHORUS (YELLOW OR WHITE) | increased above 4.3 mg/kg bw | liver to body weight ratio versus controls | Not Reported | Adult | 4-5 birds/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | no effect | body and liver weights of parents and offspring versus controls | Both Male and Female | Both Adults and Juveniles | 22 pairs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased @ 80 ppm | mortality versus controls | Male | Adult | 21/dose | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | no effect due to added Se | onset of egg laying, eggshell thickness, egg weight, egg fertility, embryo deformities versus controls | Both Male and Female | Both Adults and Juveniles | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | no effect | body weight versus controls | Male | Adult | 10/ Pb treatment; 5/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | reduced for lead shot | body weight versus all other groups | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 7.6(0.26) ppm, egg, 6.0(0.31) ppm, fem. liver, 9.6(0.95) ppm, male liver @ 10 ppm Se; 9.3(0.85) ppm, egg, 9.2(1.61) ppm, female liver, 114(25.3) ppm, male liver @ 10 ppm Se + 10 ppm Hg | mean(SE) wet wt concentration of Se in egg and liver of treated birds | Both Male and Female | Adult | 12/group | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS | no effect | histopathological lesions in gonads, liver, kidneys versus controls | Both Male and Female | Adult | 20 males, 20 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM, SELENOMETHIONINE | increased @ 3.5 mg/L (selenite) or 2.2 mg/L (selenomethionine) | serum ALT enzyme activity versus controls n high selenite and selenomethionine groups. | Male | Adult | Controls = 24 Treated = 8 |
laboratory | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | no effect | distance run in 2 seconds from a fright stimulus vs controls | Not Reported | Chick | 32, 14, 14, 14, 11 in the 0, 1, 2, 4, and 8 ppm groups | Toxicity Factor Datasets | 6 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ALDICARB | 4.44 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | decreased | eggshell quality (R-value) versus controls | Female | Adult | 5 hens; 19 eggs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | no effect | plasma glucose, NEFA, urea, or uric acid versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | liver cadmium concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LINDANE | decrease @ 20 mg/kg 7x or 3x/wk | calcium concentration in plasma and shell gland mucosa and density and size of eggshell pores | Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PARATHION | decrease | eggshell thickness, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DICOFOL | no effect | mean daily food consumption rate (169.8 g food/kg body weight) | Female | Adult | 4-8/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | 0.3 ug/g dry wt. @ 0 ppm; 0.9 - 5.0 @ 1 ppm; 4.1 - 40.1 @ 5ppm; 6.1 - 78.5 @ 10 ppm | dieldrin concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PARAQUAT | 1.5 lbs AI/acre (slope = 1.66) for exposure of 3d embryo; 2.5 lbs AI/acre (slope = 1.40) for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | Toxicity Factor Datasets | 3 or 8d of development | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PARATHION | 100% @ 5mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | 357 ppm | 11 day dietary LC50 | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | 13.8% decrease | eggshell thickness, compared to controls | Female | Adult | 3/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
VANADYL SULFATE | no effect | body weight and food consumption compared among groups | Both Male and Female | Adult | 5 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD NITRATE | decreased @ 25 ppm/3 wks, 5 ppm/12 wks | delta-aminolevulinic acid dehydratase activity in blood versus controls | Male | Adult | 20/dose; 5/dose x time group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | decreased @ 3 ppm | mean egg weight compared to controls | Female | Adult | 10 females, 3 males/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PENTACHLOROPHENOL | decrease @ 961 ug/g | total body weight, compared to control; reported as the LOAEL for the study | Not Reported | Juvenile | 6/dose | Toxicity Factor Datasets | 4 d | Laboratory |
California Sea Lion (Zalophus californianus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS | 36.11 - 88.4 ug/g wet wt (liver); 7.12 - 32.8 ug/g wet wt (kidney) | selenium concentration range in liver and kidney of dead animals | Not Reported | Not Reported | 3 | Toxicity Factor Datasets | Laboratory |
Peregrine Falcon (Falco peregrinus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | review | concentrations in eggs associated with reduced productivity (various raptor species) | Not Reported | Not Reported | Not Reported | Toxicity Factor Datasets | Laboratory | |
POLYCHLORINATED BIPHENYLS | review | concentrations in brain associated with mortality (various raptor species) | Not Reported | Not Reported | Not Reported | Toxicity Factor Datasets | Laboratory |
Long-toed Salamander (Ambystoma macrodactylum)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHOXYCHLOR | decrease @ 0.3 and 10 mg/L | mean body weight of larvae | Not Reported | Embryo, Juvenile | 30-38 eggs/dose | Toxicity Factor Datasets | Laboratory |
American Kestrel (Falco sparverius)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CARBOFURAN | increased at 63.4, 126.8, 253.6 ppm | mortality versus controls | Both Male and Female | Adult | 8 | Toxicity Factor Datasets | Laboratory | |
FENTHION | decreased to 10% of control levels | brain cholinesterase activity of birds that died | Both Male and Female | Adult | 8 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | no effect | hematocrit and hemoglobin values versus controls | Not Reported | Nestling | 9-11/group | Toxicity Factor Datasets | Day 1-Day 10 | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | increased @ 2.3, 23, 233 ng/g | incidence of malformations or edema, and EROD activity versus controls | Not Reported | Hatchling | 24-26/treatment group | Toxicity Factor Datasets | hatchling | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | blood Se concentration = 1.307 + 0.852(diet Se concentration) | relation between Se concentrations in blood (dry wt) and diet (dry wt) | Male | Adult | 40 birds | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increase at all doses 1.4, 3.5, 5.5 ppm at 25, 125, 625 mg/kg bw, respectively |
liver lead concentration | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decrease | eggshell thickness | Female | Adult | 8/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ACEPHATE, DDE (4,4'-) | decrease for both treatments | median serum cholinesterase activity 24 hr post-dose | Not Reported | Adult | 5-6/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decrease at 10 ppm | mean eggshell thickness | Female | Adult | 8-10 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
FENTHION | 77.9-92% | range of brain acetylcholinesterase inhibition (relative to control) in birds that died | Male | Adult | 14 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) | increased with PCB 105 | aminopyrine N-demethylase activity in liver | Female | Adult | 5-6/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1248 | 18.5 ug/g (5.1SD), PCBs; 0.10 ug/g (0.03 SD), dieldrin;1.02 ug/g (0.39 SD), DDE @ 3.0 ug/g | mean carcass concentrations, wet wt | Both Male and Female | Adult | 8 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PARAQUAT | no effect | percent increase over controls in lung to body weight ratio | Not Reported | Juvenile | 11/group | Toxicity Factor Datasets | Laboratory |
Deer Mouse (Peromyscus maniculatus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CHLOROCHOLINE CHLORIDE | increase @ 1-80 mg/kg | thymus weight to bw ratios | Female | Adult | 12/dose | Toxicity Factor Datasets | Laboratory |
Bullfrog (Lithobates catesbeianus formerly Rana catesbeiana)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
TOXAPHENE (POLYCHLORINATED CAMPHENES) | 99 ug/l (95% CL: 71-116 ug/l) | LC50 | Not Reported | Tadpole | 220 animals | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 360 - 900 | range of bioconcentration factors; calculated by dividing the whole body tissue dieldrin concentration by water dieldrin concentration | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | Toxicity Factor Datasets | 29 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
TRIFLUOROMETHYL-4-NITROPHENOL (3-, LAMPRECIDE) | 0.95 mg/l (95% CL: 0.72 - 1.14) | LC50 | Not Reported | Tadpole | 5 | Toxicity Factor Datasets | Gossner stages 33-38 | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Units | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|---|
MERCURIC CHLORIDE | 63.36 | 96 hour LC50 (95% Confidence Interval); based on measured concentrations | ug Hg/L | Not Reported | Not Reported | 10/dose | Toxicity Factor Datasets | Laboratory |
Western Toad (Anaxyrus boreas formerly Bufo boreas)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ZINC SULFATE | increase @ 39 mg/l | 100% mortality reported | Not Reported | Juvenile | 5-25/dose | Toxicity Factor Datasets | larvae | Laboratory |
Mourning Dove (Zenaida macroura)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 65.4-123.2 ug/g, dry wt | mean lead concentrations in femur (greater accumulation with mixed seed vs. pelleted diet) | Female | Adult | 12/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | high degree of lesions present | histological exam for hemosiderin loading in liver | Not Reported | Not Reported | 1 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | decreased at 40 ppm | body temperature at a range of ambient temperatures | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ALDRIN | 15-17 mg/kg | median lethal dosage | Not Reported | Not Reported | 21 birds | Toxicity Factor Datasets | Laboratory |
Striped Skunk (Mephitis mephitis)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PARA-AMINOPROPIOPHENONE | > 400 mg/kg | LD50 | Not Reported | Not Reported | 2/dose | Toxicity Factor Datasets | Laboratory |