Hepatic glutathione metabolism and lipid peroxidation in response to excess dietary selenomethionine and selenite in mallard ducklings

Author(s)
Hoffman, David J., Gary H. Heinz and Alexander J. Krynitsky
Year
Article Title
Hepatic glutathione metabolism and lipid peroxidation in response to excess dietary selenomethionine and selenite in mallard ducklings
Volume
27
Pages
263-271
Start Page Number
263
Final Page
271
Review

Datapoints

Displaying 1 - 10 of 10 datapoints.
Species: Mallard duck (Anas platyrhynchos)
Chemical Toxicity Endpoint Type Endpoint Description Endpoint Value Sample Size Life Cycle Stage Study Duration Type
SELENOMETHIONINE TOX-Non-Repro-Sublethal - cellular/biochemical effects incidence of altered hepatic glutathione metabolism versus controls increased @ 10,20,40 ppm 40 birds/group Juvenile 6 wks Toxicity Factor Datasets
SELENITE, SODIUM TOX-Non-Repro-Sublethal - cellular/biochemical effects incidence of altered hepatic glutathione metabolism versus controls increased @ 10,20,40 ppm 40 birds/group Juvenile 6 wks Toxicity Factor Datasets
SELENOMETHIONINE TOX-Non-Repro-Sublethal - cellular/biochemical effects hepatic malondialdehyde concentrations versus controls increased @ 20, 40 ppm 40 birds/group Juvenile 6 wks Toxicity Factor Datasets
SELENITE, SODIUM TOX-Non-Repro-Sublethal - cellular/biochemical effects hepatic malondialdehyde concentrations versus controls increased @ 40 ppm 40 birds/group Juvenile 6 wks Toxicity Factor Datasets
SELENOMETHIONINE TOX-Non-Repro-Sublethal - whole animal hepatic protein concentrations versus controls decreased @ 20, 40 ppm 40 birds/group Juvenile 6 wks Toxicity Factor Datasets
SELENITE, SODIUM TOX-Non-Repro-Sublethal - cellular/biochemical effects hepatic protein concentrations versus controls increased @ 20, 40 ppm 40 birds/group Juvenile 6 wks Toxicity Factor Datasets
SELENOMETHIONINE TOX-EXP IND - accumulation Se concentrations in livers after 6 wks of treatment increased to 4.8 (@ 10 ppm), 26.0 (@ 20 ppm), 68.0 (@ 40 ppm) ppm, wet wt 40 birds/group Juvenile 6 wks Toxicity Factor Datasets
SELENITE, SODIUM TOX-EXP IND - accumulation Se concentrations in livers after 6 wks of treatment versus controls increased to 0.4 (@ 0 ppm), 5.0 (@ 10 ppm), 3.2 (@ 20 ppm), 2.8 (@ 40 ppm) ppm, wet wt 40 birds/group Juvenile 6 wks Toxicity Factor Datasets
SELENOMETHIONINE TOX-MORT - dose-response data mortality compared to controls increased @ 40 ppm (25%) 40 birds/group Juvenile 6 wks Toxicity Factor Datasets
SELENITE, SODIUM TOX-MORT - dose-response data mortality compared to controls increased @ 40 ppm (12.5%) 40 birds/group Juvenile 6 wks Toxicity Factor Datasets

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