Subchronic organophosphorus ester-induced delayed neurotoxicity in mallards

Author(s)
Hoffman, David J., Louis Sileo and Helen C. Murray
Year
Article Title
Subchronic organophosphorus ester-induced delayed neurotoxicity in mallards
Volume
75
Pages
128-136
Start Page Number
128
Final Page
136
Review

Datapoints

Displaying 1 - 10 of 10 datapoints.
Species: Mallard duck (Anas platyrhynchos)
Chemical Toxicity Endpoint Type Endpoint Description Endpoint Value Sample Size Life Cycle Stage Study Duration Type
EPN TOX-Non-Repro-Sublethal - behavioral effects food consumption and body weight compared with controls decreased @ 90, 270 ppm 6/group Juvenile 90 d Toxicity Factor Datasets
EPN TOX-Non-Repro-Sublethal - behavioral effects incidence of hyperactivity, ataxia, and/or paralysis compared with controls increased @ all doses 6/group Juvenile 90 d Toxicity Factor Datasets
EPN TOX-Non-Repro-Sublethal - organ/system effects incidence of CNS lesions (demyelination, axonal degeneration in spinal cord) compared with controls increased @ 30, 90, 270 ppm 6/group Juvenile 90 d Toxicity Factor Datasets
EPN TOX-Non-Repro-Sublethal - cellular/biochemical effects activity of brain and plasma cholinesterase, and brain neurotoxic esterase compared with controls decreased @ all doses 6/group Juvenile 90 d Toxicity Factor Datasets
EPN TOX-Non-Repro-Sublethal - cellular/biochemical effects plasma alkaline phosphatase activity compared with controls decreased @ 90, 270 pmm 6/group Juvenile 90 d Toxicity Factor Datasets
LEPTOPHOS TOX-Non-Repro-Sublethal - whole animal body weight compared with controls decreased @ 270, 540 ppm 6/group Juvenile 90 d Toxicity Factor Datasets
LEPTOPHOS TOX-Non-Repro-Sublethal - organ/system effects incidence of CNS lesions (demyelination, axonal degeneration in spinal cord) compared with controls increased @ all doses 6/group Juvenile 90 d Toxicity Factor Datasets
LEPTOPHOS TOX-Non-Repro-Sublethal - organ/system effects brain weight compared with controls decreased @ 270 ppm 6/group Juvenile 90 d Toxicity Factor Datasets
LEPTOPHOS TOX-Non-Repro-Sublethal - cellular/biochemical effects activity of brain and plasma cholinesterase, and brain neurotoxic esterase compared with controls decreased @ all doses 6/group Juvenile 90 d Toxicity Factor Datasets
LEPTOPHOS TOX-Non-Repro-Sublethal - cellular/biochemical effects plasma alkaline phosphatase activity compared with controls decreased @ 60, 270 ppm 6/group Juvenile 90 d Toxicity Factor Datasets

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