Neurotoxic and teratogenic effects of an organophosphorus insecticide (phenyl phosphorothioic acid-o-ethyl-o-[4-nitrophenyl] ester) on mallard development

Author(s)
Hoffman, David J. and Louis Sileo
Year
Article Title
Neurotoxic and teratogenic effects of an organophosphorus insecticide (phenyl phosphorothioic acid-o-ethyl-o-[4-nitrophenyl] ester) on mallard development
Volume
73
Pages
284-294
Start Page Number
284
Final Page
294
Review

Datapoints

Displaying 1 - 8 of 8 datapoints.
Species: Mallard duck (Anas platyrhynchos)
Chemical Toxicity Endpoint Type Endpoint Description Endpoint Value Sample Size Life Cycle Stage Study Duration Type
EPN TOX-MORT - dose-response data percent survival versus controls decreased @ 12 ug/g (82%); 36 ug/g (77%); 108 ug/g (70%) 10/group Embryo 7 or 14 d Toxicity Factor Datasets
EPN TOX-Non-Repro-Sublethal - cellular/biochemical effects brain weight, acetylcholinesterase activity, neurotoxic esterase activity versus controls decreased @ 12, 36, 108 ug/g 10/group Embryo 7 or 14 d Toxicity Factor Datasets
EPN TOX-Non-Repro-Sublethal - cellular/biochemical effects brain protein content versus controls decreased @ 108 ug/g 10/group Embryo 7 or 14 d Toxicity Factor Datasets
EPN TOX-Non-Repro-Sublethal - cellular/biochemical effects plasma alkaline phosphatase, aspartate aminotransferase, cholinesterase activities, and uric acid decreased @ 36 (cholineserase only), 108 ug/g 12/group Embryo 14 d Toxicity Factor Datasets
EPN TOX-REPRO - development embryo weight and length, % normal survivors versus controls decreased @ 12, 36, 108 ug/g 12/group Embryo 14 d Toxicity Factor Datasets
EPN TOX-MORT - dose-response data % surviving to hatch versus controls decreased @ 12 ug/g (48%), 36 ug/g (29%), 108 ug/g (0%) 12/group Hatchling to hatch Toxicity Factor Datasets
EPN TOX-Non-Repro-Sublethal - cellular/biochemical effects plasma cholinesterase activity, hemoglobin and uric acid content decreased @ 12, 36 ug/g 12/group Hatchling to hatch Toxicity Factor Datasets
EPN TOX-Non-Repro-Sublethal - cellular/biochemical effects brain weight, protein content, acetylcholinesterase and neurotoxic esterase versus controls decreased @ 12, 36 ug/g 12/group Hatchling to hatch Toxicity Factor Datasets

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