Laboratory
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | 1.54(0.280) ppm, kidney; 0.637(0.134) ppm, liver; 0.042(0.007) ppm, ovary; 0.098(0.042) ppm, testis | mean(SE) wet wt concentrations of Bi in Bi-dosed birds | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | decreased | incidence of delayed hypersensitivity reactions to antigen versus controls | Male | Adult | Controls = 24 Treated = 8 |
Laboratory | Toxicity Factor Datasets | Laboratory |
SELENITE, SODIUM, SELENOMETHIONINE | decreased | blood monocyte counts after 78 days exposure versus controls | Male | Adult | Controls = 24 Treated = 8 |
Laboratory | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | decreased @ 60 ppm (regardless of methionine suppl. or protein levels) | body, liver and spleen weights, and tarsus length versus controls | Not Reported | Juvenile | 15/group | Toxicity Factor Datasets | 1-day old | Laboratory | |
SELENOMETHIONINE | increased @ 15 (GSH-peroxidase only), 60 ppm Se, adequate protein | plasma GSH-peroxidase and alkaline phosphatase activities versus controls | Not Reported | Juvenile | 15/group | Toxicity Factor Datasets | 1-day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ALDICARB | 3.60 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 7 days | Laboratory | |
ALDICARB | 6.73 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 30 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | decreased | eggshell thickness versus controls | Female | Adult | 5 hens; 19 eggs | Toxicity Factor Datasets | Laboratory | |
DDT (4,4'-) | decreased | eggshell weight versus controls | Female | Adult | 5 hens; 19 eggs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | no effect | liver glycogen concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | no effect | % packed cell volume versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM, SELENOMETHIONINE | decreased | food consumption versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | Laboratory | |
SELENITE, SODIUM, SELENOMETHIONINE | decreased (liver decreased with selenite only) | bw and liver wt versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PARATHION | no effect | egg production and fertility, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | Toxicity Factor Datasets | Laboratory | |
PARATHION | no effect | % hatchability, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-D,L-methionine, seleno-L-methionine, or selenized yeast | number of 6-day-old ducklings produced per female versus controls | Both Male and Female | Both Adults and Juveniles | 15 pairs/treatment group, 10 pairs/control group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | body weight at end of experiment | Not Reported | Juvenile | 12/dose | Toxicity Factor Datasets | 1 d at initiation | Laboratory | |
DIELDRIN | no effect | no mortality observed | Not Reported | Juvenile | 12/dose | Toxicity Factor Datasets | 1 d at initiation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DICOFOL | no effect | egg production during study period | Female | Adult | 4-8/dose | Toxicity Factor Datasets | Laboratory | |
DICOFOL | no effect | body weight at end of study | Female | Adult | 4-8/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LINDANE | decrease @ 20 mg/kg 7x and 3x/wk | egg production and vitellogenin concentration in plasma, liver and ovary | Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
LINDANE | no effect | body weight at end of study | Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decrease @ 3ppm | decrease in distance traveled in those offspring that traveled more than 10 cm from a frightening stimulus | Female | Adult | 4 adults/dose; 64-71 offspring/dose | Toxicity Factor Datasets | 10 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | decreased | number of eggs produced, egg weight, eggshell thickness compared to controls | Both Male and Female | Adult | 24 pairs/dose | Toxicity Factor Datasets | 7 and 11 months old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FENTHION | 61% | maximal brain acetylcholinesterase activity inhibition compared to control (4 hrs post-dose) | Not Reported | Juvenile | 4/group | Toxicity Factor Datasets | 1 day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLPARATHION | decreased if treatment initiated during egg laying | proportion of hens laying and number of eggs laid per hen compared to controls | Female | Adult | 12 pairs /group | Toxicity Factor Datasets | 7 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIAZINON | decreased @ 15 (aqueous), 2.0 (oil) lb/acre | embryo weight by day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory |
Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|
see citation tables | incidence of reduced growth and abnormal survivors for 42 compounds | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | incubation day 3-8 | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIISOPROPYL METHYLPHOSPHONATE | decrease | mean blood pressure, compared to baseline prior to exposure | Both Male and Female | Adult | 12 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase @ 0.25 - 5.0% | plasma alanine aminotransferase activity, from liver | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | California Counties | Lab |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased @ 2 #four shot | mortality versus controls | Both Male and Female | Adult | 12 (control); 16 (lab); 63 (field) | Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EPN | decreased @ 12, 36, 108 ug/g | brain weight, acetylcholinesterase activity, neurotoxic esterase activity versus controls | Not Reported | Embryo | 10/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory | |
EPN | decreased @ 12, 36 ug/g | brain weight, protein content, acetylcholinesterase and neurotoxic esterase versus controls | Not Reported | Hatchling | 12/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | lead only: 0.71 (+/- 0.25); lead-iron: 0.31 (+/- 0.06) ppm, wet wt | lead concentration in blood (mean +/- SE) | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
N-BUTYL ALCOHOL | 0 survival @ 100% solution, incubation days 3 or 8 exposure | embryo survival through incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | 3 or 8 days of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), LEAD COMPOUNDS, MERCURY COMPOUNDS | decreased @ 40 ppm DDE | eggshell thickness versus controls | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM, SELENOMETHIONINE | increased (40%) @ 60 ppm Se | incidence of mortality versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ALUMINUM SULFATE | decreased @ 1000 (LL) | food consumption versus controls | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | decreased @ 1200 pmm (30 d of age) | weight:length of humerus | Male | Juvenile | 36 birds/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | increased @ 0.5, 3 ppm | changes in approach behavior (maternal call stimulus) | Not Reported | Juvenile | 249 (control); 276 (0.5 ppm); 108 (3 ppm) | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | 13-20 ppm, wet wt | mean Se concentration in eggs | Female | Adult | 5 birds | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM | increased to 0.4 (@ 0 ppm), 5.0 (@ 10 ppm), 3.2 (@ 20 ppm), 2.8 (@ 40 ppm) ppm, wet wt | Se concentrations in livers after 6 wks of treatment versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | increased @ 20 ppm | serum glutamic pyruvic transaminase activity by 8 wks of treatment compared to controls | Not Reported | Juvenile | 12 birds per timexdose treatment | day old | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | decreased @ 1000 ppm B | hematocrits and hemoglobin concentrations versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease @ 5, 15 ul/egg | red blood cell and liver ALAD activity, hemoglobin concentration, plasma uric acid, and plasma ALT and AST activities compared to controls | Both Male and Female | Hatchling | 100 eggs/dose | Toxicity Factor Datasets | days 2-16 of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 28% decrease @ 40 mg/kg | eggshell index (shell weight/shell length x breadth), compared to control | Female | Adult | 9-20/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID | decrease @ 1600 ppm | growth rate measured as changes in body weight, compared to control | Both Male and Female | Juvenile | 10 animals/pen; 3 pens/dose | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
FUEL OILS | no effect | body weight and gross lesion incidence, compared to controls | Male | Adult | 4-5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CRUDE OILS | no effect | onset of laying, egg production, egg fertility, compared to controls | Female | Adult | 20 hens/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PHOSPHORUS (YELLOW OR WHITE) | reduced above 6.2 mg/kg bw | body weight versus controls | Not Reported | Adult | 4-5 birds/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | no effect | reproductive success or nest attentiveness versus controls | Both Male and Female | Adult | 22 pairs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased in birds that died, and in some 40 ppm survivors | histological changes to skin (loss of fat), muscle, liver, pancreas, kidney, lymph nodes, spleen, seminiferous tubules | Male | Adult | 21/dose | Toxicity Factor Datasets | 14 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | no effect due to added Se | liver weight, hemoglobin concentrations, hematocrit versus controls | Both Male and Female | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | 4.6(0.66) ppm @ 103 ug/g Pb; 9.3(0.82) ppm @ 207 ug/g Pb; 12(1.3) ppm @ 414 ug/g Pb; 28(4.6) ppm @ 828 ug/g Pb | mean(SE) wet wt concentrations of lead in liver | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | increased for lead shot | incidence of clinical signs versus other groups | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | increased @ 10 ppm Se, 10 ppm Hg, 10 ppm Hg + 10 ppm Se | incidence of deformities in embryos that died (1 wk or older) versus controls | Both Male and Female | Both Adults and Juveniles | 12/group | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS | 145(6.0) ppm, kidneys; 1086(72) ppm, liver; 32.1(6.3) ppm, gonads | mean(SE) wet wt Fe concentration in organs of Fe-treated birds | Both Male and Female | Adult | 20 males, 20 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LINDANE | 18-21% decrease @ 20 mg/kg 7x or 3x/wk | eggshell thickness, compared to control | Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LINDANE | 62 lbs AI/acre (slope = 8.13) for exposure of 3d embryo; 52 lbs AI/acre (slope = 9.19) for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | Toxicity Factor Datasets | 3 or 8d of development | Laboratory |
Bullfrog (Lithobates catesbeianus formerly Rana catesbeiana)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FENITROTHION | decrease response at 0.5 - 8 mg/l | avoidance response assessed by daily prodding | Not Reported | Tadpole | 10 animals/replicate; 3 replicates/dose | Toxicity Factor Datasets | 1-2 d after hatching | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PERMETHRIN | 7,033 ug/l (95% CL: 4,129-8,735 ug/l) | LC50 | Not Reported | Tadpole | 10 animals/replicate; 4 replicates/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 11.2 ug/l | LOAEL | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | Toxicity Factor Datasets | 50 d | Laboratory | |
DIELDRIN | 19.0 ug/g at 52.3 ug/l | whole body dieldrin concentration (ug/g, wet wt.) | Not Reported | Tadpole | Not Reported | Toxicity Factor Datasets | 29 d | Laboratory | |
DIELDRIN | 4.0 ug/l | NOAEL | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | Toxicity Factor Datasets | 50 d | Laboratory | |
DIELDRIN | 0.5 ug/g at 12.3 ug/l | whole body dieldrin concentration (ug/g, wet wt.) at the NOAEL | Not Reported | Tadpole | Not Reported | Toxicity Factor Datasets | 29 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
TRIFLUOROMETHYL-4-NITROPHENOL (3-, LAMPRECIDE) | 11.62 mg/kg bw (95% CL: 10.71-13.14) | LD50 | Not Reported | Tadpole | 5 | Toxicity Factor Datasets | Gossner stages 33-38 | Laboratory | |
TRIFLUOROMETHYL-4-NITROPHENOL (3-, LAMPRECIDE) | 15.35 mg/kg bw (95% CL: 8.72-21.98) | LD50 | Not Reported | Adult | 7 | Toxicity Factor Datasets | Laboratory |
American Kestrel (Falco sparverius)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PARATHION | 25% at 4.6 ppm | Not Reported | Adult | 4/group | Toxicity Factor Datasets | Laboratory | ||
PARATHION | 47% decrease at 4.6 ppm | mean brain cholinesterase activity relative to control | Not Reported | Adult | 4/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLPARATHION | increased at 2, 3 mg/kg bw | plasma glucose concentrations | Both Male and Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | variance in kestrel response time to prey stimulus | Not Reported | Adult | 6 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 1.37 (0.10 SE) mg/kg | mean DDE concentration in blood (wet wt) | Not Reported | Adult | 6 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 88.1 ppm (dry wt) | mean liver residues in birds that survived | Male | Adult | 11 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FLUORIDE, SODIUM | decreased at 2240 ppm | bonebreaking strength | Both Male and Female | Juvenile | 9-10/group | Toxicity Factor Datasets | 7 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254, POLYCHLORINATED DIBENZO-P-DIOXINS | increased @ 5 ppm | amount of liver cytoplasmic RNA | Both Male and Female | Adult | 4/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PARAQUAT | 14% @ 25 mg/kg, 18% @ 60 mg/kg | percent increase over controls in liver to body weight ratio | Not Reported | Juvenile | 11/group | Toxicity Factor Datasets | Laboratory | |
PARAQUAT | 51% @ 60 mg/kg | percent increase over controls in kidney to body weight ratio | Not Reported | Juvenile | 11/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
FENTHION | increased @ all doses | mortality versus controls | Both Male and Female | Adult | 8 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | increased | plasma enzyme activities indicative of hepatotoxicity versus controls | Not Reported | Nestling | 9-11/group | Toxicity Factor Datasets | Day 1-Day 10 | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | reduced @ 233 ng/g | liver weight, radius and femur length versus controls | Not Reported | Hatchling | 24-26/treatment group | Toxicity Factor Datasets | hatchling | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decrease at 125, 625 mg/kg bw | growth rate relative to control | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ACEPHATE, DDE (4,4'-) | no effect | prey capturing behavior | Not Reported | Adult | 5-6/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|
FENTHION | 100% | Male | Adult | 14 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) | increased with PCB 153 | aminopyrine N-demethylase and aldrin epoxidase activities in liver | Female | Adult | 5-6/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CYANIDE, SODIUM | 4.0 mg/kg bw | LD50 | Both Male and Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Western Toad (Anaxyrus boreas formerly Bufo boreas)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | decrease @ 30 and 60 ppb | temperature tolerance, estimated by heating water at 1C/3min and using onset of spasms in frogs as the endpoint | Not Reported | Juvenile | 10 animals/replicate; 2 replicates/dose | Toxicity Factor Datasets | Laboratory | |
METHYLPARATHION | decrease @ 25 and 50 ppb | temperature tolerance, estimated by heating water at 1C/3min and using onset of spasms in frogs as the endpoint | Not Reported | Juvenile | 10 animals/replicate; 2 replicates/dose | Toxicity Factor Datasets | Laboratory |
Mourning Dove (Zenaida macroura)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | no effect | mortality in dosed birds | Female | Adult | 12/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | no effect | body weight | Female | Adult | 12/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | light to moderate lesions | histological exam for hemosiderin loading in liver | Not Reported | Not Reported | 2 | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | high degree of lesions present | histological exam of acid-fast intranuclear inclusions of cells of kidney proximal convoluted tubules | Not Reported | Not Reported | 1 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | no effect | metabolic rate at a range of ambient temperatures | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1254 | no effect | body weight | Male | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Striped Skunk (Mephitis mephitis)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SODIUM MONOFLUOROACETATE | 165 mg administered to coyote (95%CI; 107 - 392 mg) | LD50; based on dose given to coyote; skunks were fed contaminated coyote tissue | Not Reported | Not Reported | 1-8 per dose | Toxicity Factor Datasets | Laboratory |
California Sea Lion (Zalophus californianus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM COMPOUNDS, CHROMIUM COMPOUNDS, COPPER COMPOUNDS, LEAD COMPOUNDS, SELENIUM COMPOUNDS, ZINC COMPOUNDS | increase | incidence of epileptiform seizures and subsequent death associated with "unusual" Se levels | Female | Adult | 1 | Toxicity Factor Datasets | 18 yr | Laboratory |
Peregrine Falcon (Falco peregrinus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | review | concentrations in brain associated with mortality (various raptor species) | Not Reported | Not Reported | Not Reported | Toxicity Factor Datasets | Laboratory |
Long-toed Salamander (Ambystoma macrodactylum)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHOXYCHLOR | decrease @ 0.3, 1, 3, 10 mg/l | responsiveness to startle and distance travelled post-startle in larvae | Not Reported | Juvenile | 30-34 eggs exposed/dose; 14-27 larvae tested/dose | Toxicity Factor Datasets | Laboratory |
Loggerhead Shrike (Lanius ludovicianus)
Chemical | Endpoint Value | Location | Type | Lab |
---|---|---|---|---|
DIELDRIN | review | Toxicity Factor Datasets | Laboratory |
Deer Mouse (Peromyscus maniculatus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CHLOROCHOLINE CHLORIDE | increase @ 1, 20, 80 mg/kg bw/d | liver weight to bw ratio | Female | Adult | 12/dose | Toxicity Factor Datasets | Laboratory |
Coyote (Canis latrans)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PARA-AMINOPROPIOPHENONE | 5.6 [3.0-10.4 (95% CI)] mg/kg | LD50 | Not Reported | Not Reported | 4/dose | Toxicity Factor Datasets | Laboratory |