Teratogenesis, toxicity and bioaccumulation in frogs exposed to dieldrin

Author(s)
Schuytema, Gerald S., Alan V. Nebeker, William L. Griffis and Karsten N. Wilson
Year
Article Title
Teratogenesis, toxicity and bioaccumulation in frogs exposed to dieldrin
Volume
21
Pages
332-350
Start Page Number
332
Final Page
350
Notes
see citation for Xenopus laevis and Rana pipiens
Review

Datapoints

Displaying 1 - 19 of 19 datapoints.
Species: Bullfrog (Lithobates catesbeianus formerly Rana catesbeiana)
Chemical Toxicity Endpoint Type Endpoint Description Endpoint Value Sample Size Life Cycle Stage Study Duration Type
DIELDRIN TOX-EXP IND - accumulation range of lipid bioconcentration factors; calculated by dividing the whole body bioconcentration values x 100 by percent lipid 36,000 - 54,000 20 animals/replicate; 4 replicates/dose Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-MORT - toxicity benchmarks LC50 34.4 ug/l (95% CL: 31.1 - 38.1 ug/l) 20 animals/replicate; 4 replicates/dose Embryo 21 d Toxicity Factor Datasets
DIELDRIN TOX-MORT - toxicity benchmarks LC50 30.3 ug/l (95% CL: 26.2 - 35.2 ug/l) 20 animals/replicate; 4 replicates/dose Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-MORT - toxicity benchmarks LOAEL, based on mortality but gross spinal deformities also observed 25.1 ug/l 20 animals/replicate; 4 replicates/dose Embryo 21 d Toxicity Factor Datasets
DIELDRIN TOX-MORT - toxicity benchmarks LOAEL 52.3 ug/l 20 animals/replicate; 4 replicates/dose Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-MORT - toxicity benchmarks NOAEL 11.0 ug/l 20 animals/replicate; 4 replicates/dose Embryo 21 d Toxicity Factor Datasets
DIELDRIN TOX-MORT - toxicity benchmarks NOAEL 12.3 ug/l 20 animals/replicate; 4 replicates/dose Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-MORT - toxicity benchmarks LC50 8.7 ug/l (95% CL: 7.8-9.7 ug/l) 20 animals/replicate; 4 replicates/dose Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-EXP IND - accumulation whole body dieldrin concentration (ug/g, wet wt.) at the LC50 12.0 ug/g at 30.3 ug/l Not Reported Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-MORT - toxicity benchmarks LOAEL 11.2 ug/l 20 animals/replicate; 4 replicates/dose Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-EXP IND - accumulation whole body dieldrin concentration (ug/g, wet wt.) 19.0 ug/g at 52.3 ug/l Not Reported Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-MORT - toxicity benchmarks NOAEL 4.0 ug/l 20 animals/replicate; 4 replicates/dose Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-EXP IND - accumulation whole body dieldrin concentration (ug/g, wet wt.) at the NOAEL 0.5 ug/g at 12.3 ug/l Not Reported Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-EXP IND - accumulation whole body dieldrin concentration (ug/g, wet wt.) at the LC50 5.1 ug/g at 8.7 ug/l Not Reported Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-EXP IND - accumulation range of bioconcentration factors; calculated by dividing the whole body tissue dieldrin concentration by water dieldrin concentration 360 - 900 20 animals/replicate; 4 replicates/dose Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-EXP IND - accumulation whole body dieldrin concentration (ug/g, wet wt.) 6.0 ug/g at 11.2 ug/l Not Reported Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-EXP IND - accumulation range of lipid bioconcentration factors; calculated by dividing the whole body bioconcentration values x 100 by percent lipid 36,000 - 90,000 20 animals/replicate; 4 replicates/dose Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-EXP IND - accumulation whole body dieldrin concentration (ug/g, wet wt.) 2.0 ug/g at 4.0 ug/l Not Reported Tadpole 4 d Toxicity Factor Datasets
DIELDRIN TOX-EXP IND - accumulation range of bioconcentration factors; calculated by dividing the whole body tissue dieldrin concentration by water dieldrin concentration 360 - 540 20 animals/replicate; 4 replicates/dose Tadpole 4 d Toxicity Factor Datasets

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