Developmental Toxicity of PCB 126 (3,3',4,4',5-Pentachlorobiphenyl) in nestling American kestrels (Falco sparverius)

Author(s)

Hoffman, David J., Mark J. Melancon, Patrice N. Klein, Clifford P. Rice, John D. Eisemann, Randy K. Hines, James W. Spann, and Grey W. Pendleton

Year

Mon, 01/01/1996 - 12:00

Article Title

Developmental Toxicity of PCB 126 (3,3',4,4',5-Pentachlorobiphenyl) in nestling American kestrels (Falco sparverius)

Volume

Pages

188-200

Start Page Number

188

Final Page

200

Review

Datapoints

Displaying 1 - 7 of 7 datapoints.

Species: American Kestrel (Falco sparverius)
Chemical	Toxicity Endpoint Type	Endpoint Description	Endpoint Value	Sample Size	Life Cycle Stage	Study Duration	Type
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL)	TOX-Non-Repro-Sublethal - whole animal	body and organ growth versus controls	decreased @ 250, 1000 ng/g bw	9-11/group	Nestling	10 d	Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL)	TOX-Non-Repro-Sublethal - organ/system effects	incidence and severity of lesions in liver, spleen, bursa, thyroid versus controls	increased @ 50,250,1000 ng/g bw	9-11/group	Nestling	10 d	Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL)	TOX-Non-Repro-Sublethal - cellular/biochemical effects	plasma enzyme activities indicative of hepatotoxicity versus controls	increased	9-11/group	Nestling	10 d	Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL)	TOX-Non-Repro-Sublethal - cellular/biochemical effects	hematocrit and hemoglobin values versus controls	no effect	9-11/group	Nestling	10 d	Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL)	TOX-Non-Repro-Sublethal - cellular/biochemical effects	hepatic monooxygenase activities versus controls	increased @ 50,250,1000 ng/g bw	9-11/group	Nestling	10 d	Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL)	TOX-EXP IND - accumulation	concentration in liver	in ng/g, wet wt: 156 (@ 50 ng/g), 380 (@ 250 ng/g), 1098 (@1000 ng/g)	9-11/group	Nestling	10 d	Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL)	TOX-Non-Repro-Sublethal - cellular/biochemical effects	relationship between hepatic PCB 126 concentrations and ratio of oxidized to reduced glutathione	positive correlation	9-11/group	Nestling	10 d	Toxicity Factor Datasets

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