Developmental Toxicity of PCB 126 (3,3',4,4',5-Pentachlorobiphenyl) in nestling American kestrels (Falco sparverius)

Author(s)
Hoffman, David J., Mark J. Melancon, Patrice N. Klein, Clifford P. Rice, John D. Eisemann, Randy K. Hines, James W. Spann, and Grey W. Pendleton
Year
Article Title
Developmental Toxicity of PCB 126 (3,3',4,4',5-Pentachlorobiphenyl) in nestling American kestrels (Falco sparverius)
Volume
34
Pages
188-200
Start Page Number
188
Final Page
200
Review

Datapoints

Displaying 1 - 7 of 7 datapoints.
Species: American Kestrel (Falco sparverius)
Chemical Toxicity Endpoint Type Endpoint Description Endpoint Value Sample Size Life Cycle Stage Study Duration Type
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) TOX-Non-Repro-Sublethal - whole animal body and organ growth versus controls decreased @ 250, 1000 ng/g bw 9-11/group Nestling 10 d Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) TOX-Non-Repro-Sublethal - organ/system effects incidence and severity of lesions in liver, spleen, bursa, thyroid versus controls increased @ 50,250,1000 ng/g bw 9-11/group Nestling 10 d Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) TOX-Non-Repro-Sublethal - cellular/biochemical effects plasma enzyme activities indicative of hepatotoxicity versus controls increased 9-11/group Nestling 10 d Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) TOX-Non-Repro-Sublethal - cellular/biochemical effects hematocrit and hemoglobin values versus controls no effect 9-11/group Nestling 10 d Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) TOX-Non-Repro-Sublethal - cellular/biochemical effects hepatic monooxygenase activities versus controls increased @ 50,250,1000 ng/g bw 9-11/group Nestling 10 d Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) TOX-EXP IND - accumulation concentration in liver in ng/g, wet wt: 156 (@ 50 ng/g), 380 (@ 250 ng/g), 1098 (@1000 ng/g) 9-11/group Nestling 10 d Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) TOX-Non-Repro-Sublethal - cellular/biochemical effects relationship between hepatic PCB 126 concentrations and ratio of oxidized to reduced glutathione positive correlation 9-11/group Nestling 10 d Toxicity Factor Datasets

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