PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) |
TOX-Non-Repro-Sublethal - cellular/biochemical effects |
aminopyrine N-demethylase and aldrin epoxidase activities in liver |
increased with PCB 153 |
5-6/group |
Adult |
4 wk |
Toxicity Factor Datasets |
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) |
TOX-Non-Repro-Sublethal - cellular/biochemical effects |
aminopyrine N-demethylase activity in liver |
increased with PCB 105 |
5-6/group |
Adult |
4 wk |
Toxicity Factor Datasets |
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) |
TOX-Non-Repro-Sublethal - cellular/biochemical effects |
7-ethoxyresorufin O-deethylase and aldrin epoxidase activities in liver |
increased with PCB 126 |
5-6/group |
Adult |
4 wk |
Toxicity Factor Datasets |
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) |
TOX-Non-Repro-Sublethal - cellular/biochemical effects |
hepatic porphyrin levels |
no effect |
5-6/group |
Adult |
4 wk |
Toxicity Factor Datasets |
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) |
TOX-Non-Repro-Sublethal - organ/system effects |
liver weight |
no effect |
5-6/group |
Adult |
4 wk |
Toxicity Factor Datasets |
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) |
TOX-EXP IND - accumulation |
PCB concentrations in pooled adipose tissue |
2.4 (control), 119.0 (PCB 153), 182.0 (PCB 105), 3.3 (PCB 126) mg/kg, wet weight |
5-6/group |
Adult |
4 wk |
Toxicity Factor Datasets |