TOX-EXP IND - accumulation
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | one shot: 180.4 (18.1), female; 5.0 (0.6), male two shot: 183.4 (21.2), female; 15.9 (4.1), male |
mean (SE) lead residues in femur | Both Male and Female | Adult | 20 females, 10 males/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 10.3(0.7) ppm in femur, 14.1(0.6) ppm in liver, 6.8(0.2) in kidneys | mean(SE) dry wt tungsten concentrations in tissues of tungsten-iron-dosed birds | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory | |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 4.3(0.7) ppm in femur, non-detect. in liver, 2.4(0.2) in kidneys | mean(SE) dry wt tungsten concentrations in tissues of tungsten-polymer-dosed birds | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory | |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 250.6(39.0) ppm in femur, 78.3(9.7) ppm in liver, 256.3(22.2) in kidneys | mean(SE) dry wt lead concentrations in tissues of lead-dosed birds | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | 0.3 ug/g dry wt. @ 0 ppm; 0.9 - 5.0 @ 1 ppm; 4.1 - 40.1 @ 5ppm; 6.1 - 78.5 @ 10 ppm | dieldrin concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | ppm wet wt: 4.15 (3.56), blood; 13.85 (7.96), liver; 577.07 (156.4), femur@ 2 #four shot | mean (2SE) lead concentrations in liver, femur and blood | Female | Adult | 5 birds | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD NITRATE | increased @ 25 ppm/3wks | accumulation in livers and kidneys versus controls | Male | Adult | 20/dose; 5/dose x time group | Toxicity Factor Datasets | 1 yr | Laboratory | |
LEAD NITRATE | increased @ 5 ppm diet (66 +/-13 ppm blood) and @ 25 ppm diet (154 +/-28 ppm blood) | lead concentration in blood after 12 weeks exposure (mean +/- SE) versus controls | Male | Adult | 20/dose; 5/dose x time group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ALUMINUM SULFATE | see table | Ca, Al, P concentrations in femur for different treatments after 2 and 10 wks of treatment | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM | increased to 0.4 (@ 0 ppm), 5.0 (@ 10 ppm), 3.2 (@ 20 ppm), 2.8 (@ 40 ppm) ppm, wet wt | Se concentrations in livers after 6 wks of treatment versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 80.7 ug/g lipid, 30.1 ug/g skin, 1.6 ug/g brain, 4.1 ug/g liver, 1.8 ug/g muscle at 49.3 ug/g food | mean of day 5, 7, 8 (approx. steady state) tissue concentrations | Not Reported | Juvenile | 6 | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | Equation: fecal Pb conc./fecal acid insoluble ash content = 61 + (1.06 x sediment Pb conc.) | relation between waterfowl fecal lead concentration (dry wt) and sediment lead concentration (dry wt) | Not Reported | Not Reported | 521 fecal analyses at 11 wetlands (at least 20 per wetland) | Coeur d'Alene and St. Joe River Basins | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased (12-fold) | selenium concentrations in pectoral muscle | Male | Adult | Controls = 24 Treated = 8 |
Laboratory | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | liver cadmium concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | no effect | liver Cu concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | no effect | liver Zn concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | kidney Cd concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDT (Technical Grade Mixture) | see citation | table of DDE, DDD and DDT residues in 21 tissues following varying times after application | Not Reported | Not Reported | 1-6/sample | Sandusky Bay, Port Clinton | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased @ 7, 14, 21 d post-dose | concentration of lead in blood versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | increased @ 12.5, 50, 200, 800 ppm diet | kidney, blood, liver, and feather concentrations of Ni compared to controls | Both Male and Female | Adult | 6 pairs/group | Toxicity Factor Datasets | Laboratory | |
NICKEL SULFATE | 1.94 (kidney), 0.52 (liver), 0.139 (blood), 68.06 (feathers) ppm, wet wt | mean tissue concentrations @ 800 ppm Ni in diet | Both Male and Female | Adult | 6 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | 0.10 (@ 0 ppm), 10.13 (@ 5 ppm), 16.25 (@ 10 ppm), 42.21 (@ 20 ppm) ppm, wet wt | mean Cd concentrations in liver by 12 wks of treatment | Not Reported | Juvenile | 12 birds per timexdose treatment | day old | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | 0.51-0.54 ppm blood, 2.07-2.41 ppm kidney, 2.35-2.26 ppm liver, 0.74-0.97 ppm breast muscle, 0.47-0.51 ppm brain, 0.88 ppm eggs @ 0.5 ppm in diet | range of mean Hg (ppm wet-weight) concentrations in wild-strain males and females | Both Male and Female | Adult | 6-9 (9 breeding pairs/dose) | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased @ all doses | Pb concentrations in wing bone and liver | Both Male and Female | Not Reported | 5-6/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | 130(10.1) ppm in kidneys, 0.19(0.06) ppm in liver | mean(SE) wet wt concentration of bismuth in organs | Both Male and Female | Adult | 5 males, 5 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
RADIONUCLIDES | 131I 10d; 140Ba 22d; 51Cr 86d; 58Co 32d; 75Se 26d; 65Zn 67d; 134Cs 10d; 60Co 67d; 137Cs 11 d | mean biological half-lives for whole-body retention of 9 radionuclides; ducks exposed in field for varying time periods then depurated in laboratory to determine half-life | Both Male and Female | Not Reported | 4-6/sample | Idaho National Engineering Lab | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
ENDRIN | breast muscle=non-detect.; liver=non-detect.-0.05; fat=non-detect.-0.50 ppm, wet wt | tissue endrin residues | Not Reported | Not Reported | 7-10 animals | Wenatchee | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 78.2 (carcass); 61.6 (egg); 4.1 (brain) ppm, wet wt | DDE residues in whole carcass, egg contents, and brain | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
MERCURY COMPOUNDS | 2.5 (carcass); 1.25 (egg); 23.7 (kidney) ppm, wet wt | mercury residues in whole carcass, egg contents, and kidneys | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
LEAD COMPOUNDS | 3.7 (carcass); 2.5 (egg); 2.5 (eggshells); 9.6 (bone) ppm, wet wt @ 100 ppm lead; 3.4 (carcass); 0.88 (egg); 2.8 (eggshells); 35.0 (bone) ppm, wet wt @ 100 ppm lead + DDE |
lead residues in whole carcass, egg contents, eggshells, and bone | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased @ 2 ppm or greater | Se concentrations in liver versus controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 10.6 +/- 2.2 ppm nasal gland, 16.1 +/- 5.1 ppm liver, 5.8 +/- 1.1 ppm kidney, 1.9 +/- 0.1 ppm brain @ 100 ppm diet | mean (+/- SE) DDE levels (ppm wet weight) | Both Male and Female | Juvenile | 4 | Toxicity Factor Datasets | 3-5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | 9.2(0.52) ppm with seleno-D,L-methionine; 8.9(0.35) ppm with seleno-L-methionine; 6.6(0.37) ppm with selenized yeast | mean(SE) wet wt concentrations of selenium in 8th egg laid | Female | Adult | 15 pairs/treatment group, 10 pairs/control group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | liver: C = 7.4(1-e^-0.382t) muscle: C = 8.0(1-e^-0.037t) |
selenium accumulation equations | Both Male and Female | Adult | 3 | Toxicity Factor Datasets | Laboratory | |
SELENOMETHIONINE | liver: C = 7.4e^-0.037t muscle: C = 5.6e^-0.023t liver at peak body burden: C = 22.6e^-0.246t + 2.5 e^-0.008t muscle at peak body burden: C = 6.4e^-0.029t Loss phase for blood at peak body burden: C = 12.0e^-0.071t |
selenium depuration equations | Both Male and Female | Adult | 3 | Toxicity Factor Datasets | Laboratory | |
SELENOMETHIONINE | liver: 18.7 d muscle: 30.1 d |
half life of selenium in tissues | Both Male and Female | Adult | 3 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ENDRIN | see citation | figures of carcass and blood endrin concentrations during elimination period (0-64d) | Male | Adult | 2-5/sample | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | 1.0-22.7 (liver), 2.7-74.4 (kidney) ppm, wet wt | Ni concentrations (ranges) in liver and kidney in ducklings that died @ 1200 ppm | Both Male and Female | Juvenile | 36 birds/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | 10.8 (@ 15 ppm Se), 56.0 (@ 60 ppm) ppm Se, wet wt 11.0 (@ 1000 ppm B) ppm B, wet wt |
geometric mean Se and B concentrations in liver | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
BORIC ACID, SELENOMETHIONINE | 22.5 (@ 15 ppm Se w/out B), 41.9 (@ 15 ppm Se w/B) ppm Se, wet wt 13.0 (@ 1000 ppm B) ppm B, wet wt |
geometric mean Se and B concentrations in liver | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 1.23 +/- 0.12 ug/g wet weight | mean +/- SE p,p'-DDE concentration in shell gland mucosa | Female | Adult | Not Reported | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PHOSPHORUS (YELLOW OR WHITE) | positive correlation | P4 concentration in fat versus dose | Male | Adult | 4-5 birds/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 7.6(0.26) ppm, egg, 6.0(0.31) ppm, fem. liver, 9.6(0.95) ppm, male liver @ 10 ppm Se; 9.3(0.85) ppm, egg, 9.2(1.61) ppm, female liver, 114(25.3) ppm, male liver @ 10 ppm Se + 10 ppm Hg | mean(SE) wet wt concentration of Se in egg and liver of treated birds | Both Male and Female | Adult | 12/group | Toxicity Factor Datasets | 18 mo | Laboratory | |
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 16(0.8) ppm, egg, 22(1.5) ppm, fem. liver, 71(8.9) ppm, male liver @ 10 ppm Hg; 17(0.6) ppm, egg, 21(4.3) ppm, female liver, 65(4.1) ppm, male liver @ 10 ppm Se + 10 ppm Hg | mean(SE) wet wt concentration of Hg in egg and liver of treated birds | Both Male and Female | Adult | 12/group | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1242 | 105.0 (7.7 SE) mg Aroclor 1260/kg egg @ 150 ppm | PCB concentration in eggs (PCB resembled Aroclor 1260 profile most closely) | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 0.021 - 0.028 ppm wet wt @ 0 ppm; 5.8 (0.32 SE; range 4.28-7.23) ppm wet wt @ 3 ppm | mean and range of DDE egg concentrations | Female | Adult | 8 eggs/dose | Toxicity Factor Datasets | 10 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | 2.116 (@ 2 ppm), 19.510 (@ 20 ppm), 96.600 9@ 200 ppm) ppm, wet wt | mean Cd concentrations in liver after 90 d of treatment | Both Male and Female | Adult | 20 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory | |
CADMIUM CHLORIDE | 4.627 (@ 2 ppm), 54.333 (@ 20 ppm), 77.222 (@ 200 ppm) ppm, wet wt | mean Cd concentrations in kidneys after 90 d of treatment | Both Male and Female | Adult | 20 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 38 ug/g wet weight egg (yolk + white), 1.20 ug/g wet weight egg shell gland mucosa @ 40 mg/kg | mean DDE concentrations | Female | Adult | 7-9 | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | 55-65 ppm | range of wet wt concentrations of Aroclor 1254 in adult carcasses | Both Male and Female | Adult | 22 pairs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Condition | Lab |
---|---|---|---|---|---|---|---|---|---|
LINDANE | serum (0.13); fat (0.20); muscle (0.70); kidney (0.02); liver (0.02); brain (0.01) ppm @ 20 mg/kg 2x/wk | mean lindane residue levels | Female | Adult | 5/dose | Toxicity Factor Datasets | laying | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | 0.822 (0.059-21.60) ppm wet wt | geometric mean liver concentration (range) | Not Reported | Not Reported | 39 birds | Ebro Delta Natural Park | Toxicity Factor Datasets | ITALY |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM | increased @ 100 ppm ( 0.4 ppm, dry wt), 300 ppm (0.8 ppm, dry wt) | accumulation of arsenic in brain tissue (geometric means in parentheses) | Both Male and Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID | 2 ug/g @ control; 4 ug/g @ 100 ppm; 5 ug/g @ 400 ppm; 51 ug/g @ 1600 ppm | boron accumulation in brain (geometric mean; ug/g dry weight) | Both Male and Female | Juvenile | 10 animals/pen; 3 pens/dose | Toxicity Factor Datasets | 1 d | Laboratory |
Double-crested Cormorant (Phalacrocorax auritus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific |
---|---|---|---|---|---|---|---|---|
MERCURY (elemental), POLYCHLORINATED BIPHENYLS | 14 | Ratio of concentration in carcass (0.64 ppm wet wt mercury) to dietary concentration (fish) | Not Reported | Adult | 10 carcasses | Lake Pointsett, Dry Lake | Toxicity Factor Datasets | |
MERCURY (elemental), POLYCHLORINATED BIPHENYLS | 0.29 ppm wet wt mercury | mean concentration in eggs | Female | Adult | 5 eggs | Lake Pointsett, Dry Lake | Toxicity Factor Datasets | |
MERCURY (elemental), POLYCHLORINATED BIPHENYLS | 0.28 ppm wet wt mercury | concentration in liver | Not Reported | Nestling | 5 birds | Lake Pointsett, Dry Lake | Toxicity Factor Datasets | 2-4 wks old |
MERCURY (elemental), POLYCHLORINATED BIPHENYLS | 7.98 ppm wet wt mercury | concentration in liver | Both Male and Female | Adult | 5 birds | Lake Pointsett, Dry Lake | Toxicity Factor Datasets |
Mourning Dove (Zenaida macroura)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 2.80-4.98 ug/g, dry wt | mean lead concentrations in liver (greater accumulation with mixed seed vs. pelleted diet) | Female | Adult | 12/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | 47.2-190.7 ug/g, dry wt | mean lead concentrations in kidney (greater accumulation with mixed seed vs. pelleted diet) | Female | Adult | 12/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Error | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 169.2 ug/g, dry wt. | lead concentration in bone | Not Reported | Adult | 10 birds | Toxicity Factor Datasets | 33.9 SE | Laboratory | |
LEAD (elemental) | 198.2 ug/g, dry wt | lead concentration in bone | Not Reported | Adult | 10 birds | Toxicity Factor Datasets | 39.9 SE | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 639.43 and 345.95 ug/g, dry wt | lead concentration in kidneys of treated birds | Not Reported | Not Reported | 2 | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | 58.35 and 214.71 ug/g, dry wt | lead concentrations in livers of dosed birds | Not Reported | Not Reported | 2 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
ALDRIN, DIELDRIN | <0.1 ppm aldrin, 3.8 ppm dieldrin, 0.3 ppm DDT and metabolites, wet wt | post-mortem whole body concentrations | Not Reported | Not Reported | 1 bird | Toxicity Factor Datasets |
American Kestrel (Falco sparverius)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) | 2.4 (control), 119.0 (PCB 153), 182.0 (PCB 105), 3.3 (PCB 126) mg/kg, wet weight | PCB concentrations in pooled adipose tissue | Female | Adult | 5-6/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | in ng/g, wet wt: 156 (@ 50 ng/g), 380 (@ 250 ng/g), 1098 (@1000 ng/g) | concentration in liver | Not Reported | Nestling | 9-11/group | Toxicity Factor Datasets | Day 1-Day 10 | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 984.1-1438.6 ppm (dry wt) | brain residues in birds that died | Male | Adult | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 232.9 ppm (dry wt) | mean brain residues in birds that survived | Male | Adult | 11 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 507-877.1 ppm (dry wt) | liver residues in birds that died | Male | Adult | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 88.1 ppm (dry wt) | mean liver residues in birds that survived | Male | Adult | 11 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Location | Type |
---|---|---|---|
POLYCHLORINATED BIPHENYLS | review | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increase at all doses 1.4, 3.5, 5.5 ppm at 25, 125, 625 mg/kg bw, respectively |
liver lead concentration | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increase at 125, 625 mg/kg bw 7.2, 15.5 ppm at 125, 625 mg/kg bw, respectively |
kidney lead concentrations | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1248 | 18.5 ug/g (5.1SD), PCBs; 0.10 ug/g (0.03 SD), dieldrin;1.02 ug/g (0.39 SD), DDE @ 3.0 ug/g | mean carcass concentrations, wet wt | Both Male and Female | Adult | 8 pairs/group | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1248 | 5.60 ug/g (1.15 SD), PCBs; 0.15 ug/g (0.05 SD), dieldrin; 0.15 ug/g (0.07 SD), DDE @ 3.0 ug/g | mean egg concentrations, wet wt | Female | Adult | 8 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | no effect | lead concentration in eggshell | Female | Adult | 16 pairs/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | 62.0 ppm tibia, 13.5 ppm humeri at 50 ppm | lead concentrations in bones | Female | Adult | 16 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increase at 50 ppm 1.3 ppm (1.00 SD) males; 2.4 ppm (1.40 SD) females |
mean lead concentration in liver | Both Male and Female | Adult | 16 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DICOFOL | 8.11 (fat), 0.28 (liver) ug/g @ 0.3 mg/kg bw/d | sum of geometric mean tissue concentrations (wet wt) of dicofol and metabolites (dichlorobenzophenone, mono-dechlorinated dicofol, dichlorobenzhydrol, DDE) | Female | Adult | 2-4/group | Toxicity Factor Datasets | Laboratory | |
DICOFOL | 82.36 (fat), 4.93 (liver), 1.15 (brain), 0.84 (oviduct) ug/g @ 3.0 mg/kg bw/d | sum of geometric mean tissue concentrations (wet wt) of dicofol and metabolites (dichlorobenzophenone, mono-dechlorinated dicofol, dichlorobenzhydrol, DDE) | Female | Adult | 2-4/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | 1.13 ppm blood at 212 ppm; 1.69 ppm blood at 448 ppm | mean lead concentration in blood | Both Male and Female | Adult | 8-14/group | Toxicity Factor Datasets | 1-2 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | 1.05 (0.05 SE) ppm (wet wt) | lead concentration in liver | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | 0.24 ug/g at study area, 0.087 ug/g at reference area |
mean lead concentration in blood (wet wt) | Both Male and Female | Nestling | 30 (study area) 22 (reference) |
Coeur D'Alene River | Toxicity Factor Datasets |
Peregrine Falcon (Falco peregrinus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, POLYCHLORINATED BIPHENYLS | log DDE in eggs = 0.9723 + 0.8506(log DDE in plasma); r = 0.66 | log-log relationship between DDE in plasma of female birds and DDE in eggs | Female | Adult | 10 females | Rankin Inlet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 1.89 (1.27-2.43) -6.96 (3.28-13.37) ppm, wet wt | annual mean (range) concentrations in eggs | Female | Adult | 3-6 eggs/year | Amchitka Island | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Condition | Countries |
---|---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE | 0.9-7.2 (DDT); 10.4-41.8 (DDE); 0.9-3.4 (DDD); 0.3-2.0 (dieldrin); 0.2-1.2 (heptachlor epoxide) | range of concentrations in eggs (ppm, wet wt) | Female | Adult | 7 eggs | Peace, Slave, and Mackenzie Rivers | Toxicity Factor Datasets | CANADA | |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE | 37.3 (DDT), 284 (DDE), 39.5 (DDD), 3.3 (dieldrin), 4.4 (heptachlor epoxide) | mean residue concentrations in fat (ppm, wet wt) | Female | Adult | 9 birds | Peace, Slave, and Mackenzie Rivers | Toxicity Factor Datasets | nesting | CANADA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN | 48.0 (DDE), 3.35 (DDD), 1.02 (DDT), 1.45 (dieldrin) | mean concentrations of pesticides in eggs (ppm, dry weight) | Female | Adult | 2 eggs | Yukon River | Toxicity Factor Datasets |
Bullfrog (Lithobates catesbeianus formerly Rana catesbeiana)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 360 - 900 | range of bioconcentration factors; calculated by dividing the whole body tissue dieldrin concentration by water dieldrin concentration | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | Toxicity Factor Datasets | 29 d | Laboratory | |
DIELDRIN | 36,000 - 90,000 | range of lipid bioconcentration factors; calculated by dividing the whole body bioconcentration values x 100 by percent lipid | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | Toxicity Factor Datasets | 29 d | Laboratory |
Great Horned Owl (Bubo virginianus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DIELDRIN | 0.07 +/- 0.03 ppm (uncontaminated site); 0.34 +/- 0.21 ppm (contaminated site) | mean (+/- SE) concentrations in plasma | Not Reported | Adult | 2 birds on contaminated sites; 5 birds on uncontaminated sites | Rocky Mountain Arsenal National Wildlife Refuge | Toxicity Factor Datasets |
DIELDRIN | 0.01 +/- 0.003 ppm (uncontaminated site); 0.22 +/- 0.03 ppm (contaminated site) | mean (+/- SE) concentrations in plasma | Not Reported | Juvenile | 6 birds on contaminated sites; 10 birds on uncontaminated sites | Rocky Mountain Arsenal National Wildlife Refuge | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
ENDRIN | breast muscle=0.02 ppm, wet wt | tissue endrin residues | Not Reported | Not Reported | 1 animal | Wenatchee | Toxicity Factor Datasets |
California Ground Squirrel (Spermophilus beecheyi)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SODIUM MONOFLUOROACETATE | 182-1309 ppb wet wt. @ 0.8 mg/kg; 535-9754 ppb wet wt. @ 4.8 mg/kg | range of fluoroacetate residues in brain, caecum, kidney, liver, spleen, muscle and lung tissue of dead squirrels | Not Reported | Adult | 2/dose | Toxicity Factor Datasets | Laboratory |
California Newt (Taricha torosa)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
CHLORDANE | 8,906 ppb, range; 4,954 - 15, 609 ppb | mean and range of total technical chlordane residues in newt carcasses (without liver and stomach) 14 days after application | Both Male and Female | Both Adults and Juveniles | 4 | Toxicity Factor Datasets | CANADA | |
CHLORDANE | 2,116 ppb, range; 1,354 - 3,783 ppb | mean and range of total technical chlordane residues in newt carcasses (without liver and stomach) 451 days after application | Both Male and Female | Both Adults and Juveniles | 6 | Toxicity Factor Datasets | CANADA |
Great Horned Owl (Bubo virginianus), Northern Flicker (Colaptes auratus), Mourning Dove (Zenaida macroura)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
ENDRIN | brain=greater than or equal to 0.8 ppm, wet wt | tissue endrin residues | Not Reported | Not Reported | 1-3 animals | Wenatchee | Toxicity Factor Datasets |
ENDRIN | brain=greater than or equal to 0.8 ppm, wet wt | tissue endrin residues | Not Reported | Not Reported | 1-3 animals | Wenatchee | Toxicity Factor Datasets |
Pallid Bat (Antrozous pallidus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 5.8 ppm; range, 3.6-8.2 ppm (wet wt) | mean and range of concentration in carcass, wet wt | Both Male and Female | Adult | 4 bats | near cities | Toxicity Factor Datasets | MEXICO |