Subchronic hepatotoxicity of selenomethionine ingestion in mallard ducks

Author(s)
Hoffman, David J., Gary H. Heinz, Leonard J. LeCaptain, Christine M. Bunck and David E. Greene
Year
Article Title
Subchronic hepatotoxicity of selenomethionine ingestion in mallard ducks
Volume
32
Pages
449-464
Start Page Number
449
Final Page
464
Review

Datapoints

Displaying 1 - 7 of 7 datapoints.
Species: Mallard duck (Anas platyrhynchos)
Chemical Toxicity Endpoint Type Endpoint Description Endpoint Value Sample Size Life Cycle Stage Study Duration Type
SELENOMETHIONINE TOX-Non-Repro-Sublethal - organ/system effects incidence of liver histopathological lesions, liver:body wt ratios versus controls increased @ 32 ppm 10 birds/group Adult 14 wks Toxicity Factor Datasets
SELENOMETHIONINE TOX-Non-Repro-Sublethal - cellular/biochemical effects plasma alkaline phosphatase activity and total protein levels versus controls increased @ 32 ppm 10 birds/group Adult 14 wks Toxicity Factor Datasets
SELENOMETHIONINE TOX-Non-Repro-Sublethal - whole animal body weight, liver DNA:RNA ratio, hematocrit compared to controls decreased @ 32 ppm 10 birds/group Adult 14 wks Toxicity Factor Datasets
SELENOMETHIONINE TOX-Non-Repro-Sublethal - cellular/biochemical effects hemoglobin concentration compared to controls decreased @ 16, 32 ppm 10 birds/group Adult 14 wks Toxicity Factor Datasets
SELENOMETHIONINE TOX-Non-Repro-Sublethal - cellular/biochemical effects plasma glutathione peroxidase activity versus controls increased @ 2 ppm or greater 10 birds/group Adult 14 wks Toxicity Factor Datasets
SELENOMETHIONINE TOX-Non-Repro-Sublethal - organ/system effects liver reduced gluthathione, oxidized glutathione, malondialdehyde concentrations versus controls increased @ 16, 32 ppm 10 birds/group Adult 14 wks Toxicity Factor Datasets
SELENOMETHIONINE TOX-EXP IND - accumulation Se concentrations in liver versus controls increased @ 2 ppm or greater 10 birds/group Adult 14 wks Toxicity Factor Datasets

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