Aquatic birds
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
XYLENE | no effect | embryo survival, size, and incidence of abnormalities through incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | 3 or 8 days of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), LEAD COMPOUNDS, MERCURY COMPOUNDS | decreased with both treatments | eggshell thickness versus controls | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 78.2 (carcass); 61.6 (egg); 4.1 (brain) ppm, wet wt | DDE residues in whole carcass, egg contents, and brain | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | 0.46 (@ 0 ppm), 4.63 (@ 2 ppm), 54.33 (@ 20 ppm), 77.22 (@ 200 ppm) ppm, wet wt | mean Cd concentrations in kidneys (ppm, wet wt) by 90 days | Both Male and Female | Adult | 10 birds | Toxicity Factor Datasets | first year | Laboratory | |
CADMIUM CHLORIDE | 0.03 (@ 0 ppm), 0.02 (@ 2 ppm), 0.72 (@ 20 ppm) 8.47 (@ 200 ppm) ppm, wet wt | mean Cd concentrations in testes (ppm, wet wt) by 90 days | Male | Adult | 5 birds | Toxicity Factor Datasets | first year | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ALUMINUM SULFATE | decreased @ 1000 (LL), 1000 (LH), 5000 ppm (LH) | growth of body components (tarsus, culmen) versus controls | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | 1 d | Laboratory | |
ALUMINUM SULFATE | increased to 61% @ 1000 (LL), 100% @ 5000 (LL) | mortality versus controls | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | decreased @ 1200 ppm | body wt by 28 d of age | Both Male and Female | Juvenile | 36 birds/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
NICKEL SULFATE | no effect | bill length | Both Male and Female | Juvenile | 36 birds/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SALINE WATER | increased @ 20,000 umhos/cm and above | thymus size versus controls | Not Reported | Juvenile | 10 birds/group | Toxicity Factor Datasets | 2 d | Laboratory | |
SALINE WATER | decreased @ 20,000 and 21,500 umhos/cm | body weight by day 14 versus controls | Not Reported | Juvenile | 10 birds/group | Toxicity Factor Datasets | 2 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | see figure and table | figure and table showing decline of Hg in carcass, liver, and kidney over time | Male | Adult | 3-5 birds/group | Toxicity Factor Datasets | Laboratory | |
METHYLMERCURY DICYANDIAMIDE | 9.10 (whole body), 4.46 (carcass), 16.5 (liver), 17.6 (kidney) ppm, wet wt | mean Hg concentrations after 2 wk exposure | Male | Adult | 3-5 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM | increased @ 20, 40 ppm | hepatic protein concentrations versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
SELENOMETHIONINE | increased to 4.8 (@ 10 ppm), 26.0 (@ 20 ppm), 68.0 (@ 40 ppm) ppm, wet wt | Se concentrations in livers after 6 wks of treatment | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | decreased @ 20 ppm | packed cell volume and hemoglobin concentration by 8 wks of treatment compared to controls | Not Reported | Juvenile | 12 birds per timexdose treatment | day old | Toxicity Factor Datasets | Laboratory |
CADMIUM CHLORIDE | increased @ 20 ppm | incidence of kidney lesions by 12 wks of treatment compared to controls | Not Reported | Juvenile | 12 birds per timexdose treatment | day old | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | increased @ 15, 60 ppm Se (with and w/out B), 1000 ppm B | incidence of plasma chemistry changes versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
BORIC ACID, SELENOMETHIONINE | increased @ 15 ppm Se (with and w/out B), 1000 ppm B | incidence of plasma chemistry changes versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM | no effect | hematocrit and hemoglobin | Both Male and Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory | |
ARSENATE, SODIUM | increased @ 100 ppm ( 0.4 ppm, dry wt), 300 ppm (0.8 ppm, dry wt) | accumulation of arsenic in brain tissue (geometric means in parentheses) | Both Male and Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | 60(14.2) ppm, wet wt @ 40 ppm; 51(5.2) ppm, wet wt @ 80 ppm | mean liver concentrations (SE) in ducklings fed selenomethionine that died | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | nasal gland secretion volume | Both Male and Female | Juvenile | 5-11 | Toxicity Factor Datasets | 3-5 mo | Laboratory | |
DDE (4,4'-) | no effect | nasal gland and kidney Na-K-ATPase activity, following exposure to 100% seawater | Both Male and Female | Juvenile | 4-5 | Toxicity Factor Datasets | 3-5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase @ 3% | body weight | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 18 wks | Laboratory | |
CRUDE OILS | increase @ 1 and 3% | daily food intake rate | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 18 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
BORIC ACID | decrease @ 30, 300, 1000 ppm | hatchling weight gain over 21 d, compared to controls | Both Male and Female | Hatchling | 11-23/dose | Toxicity Factor Datasets | Laboratory | |
BORIC ACID | Egg; 3 ug/g @ 30 ppm, 13 ug/g @ 300 ppm, 49 ug/g @ 1000 ppm: Liver; 15 ug/g @ 300 ppm, 33 ug/g @ 1000 ppm: Brain; 14 ug/g @ 300 ppm, 41 ug/g @ 1000 ppm | boron concentrations in adult tissues (geometric mean; ug/g dry weight). | Both Male and Female | Adult | 10-20/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
COREXIT 9527 | increase | plasma alanine aminotransferase activity, compared to control | Not Reported | Juvenile | 25/dose | Toxicity Factor Datasets | 4 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
TRIMETHYLTIN CHLORIDE | increase @ 50 ppm | incidence of mild to marked degeneration of neurons of the pons, medulla oblongata, gray matter of the spinal cord and pyrimidal cells of the cerebral cortex; mild to moderate lympoid depletion of spleen and thymus; atrophy of myofibers in skeletal and ca | Not Reported | Juvenile | 5/dose | Toxicity Factor Datasets | 3-4 d | Laboratory | |
TRIMETHYLTIN CHLORIDE | 17% decrease @ 5 ppm | body weight | Not Reported | 5/dose | Toxicity Factor Datasets | 3-4 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PHOSPHORUS (YELLOW OR WHITE) | 91.1 ug/g | No Observable Effect Level, based on mortality, pathology, clinical signs | Both Male and Female | Adult | 5 males, 5 females/dose | Toxicity Factor Datasets | Laboratory | |
PHOSPHORUS (YELLOW OR WHITE) | 679.8 ug/g (194.3-442.6 95% CI ) | LC50 | Both Male and Female | Adult | 5 males, 5 females/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EMAMECTIN BENZOATE | no effect | numbers of eggs laid and hatched, eggshell thickness, and 14-day hatchling survival versus controls | Both Male and Female | Both Adults and Juveniles | 16 pairs/group | Toxicity Factor Datasets | 22 weeks | Laboratory | |
EMAMECTIN BENZOATE | no effect | mortality versus controls | Both Male and Female | Adult | 16 pairs/group | Toxicity Factor Datasets | 22 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | decreased in birds that died | mean weights of heart, spleen, pancreas, testis versus controls | Male | Adult | 21/dose | Toxicity Factor Datasets | 1 yr | Laboratory | |
SELENOMETHIONINE | 33(7) ppm @ 10 ppm Se, 49(9) ppm @ 20 ppm Se, 87(11) ppm @ 40 ppm Se, 99(9) ppm in birds that died | mean (SE) dry wt concentrations of selenium in liver | Male | Adult | 10-25 | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | increased @ 3.5 ppm Se | survival between 7 and 14 days post-hatch versus controls | Both Male and Female | Juvenile | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory | |
BORIC ACID, SELENOMETHIONINE | reduced @ 7 ppm | duckling production versus 3.5 ppm Se group | Both Male and Female | Both Adults and Juveniles | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | 3.0(0.30) ppm @ 642 ug/g Pb; 6.8(0.84) ppm @ 1284 ug/g Pb | mean (SE) wet wt Pb concentrations in blood | Male | Adult | 10/ Pb treatment; 5/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | 9.1(0.61) ppm @ 642 ug/g Pb; 16(1.5) ppm @ 1284 ug/g Pb | mean (SE) wet wt Pb concentrations in liver | Male | Adult | 10/ Pb treatment; 5/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | increased for lead shot | plasma activities of alanine aminotransferase, creatine phosphokinase, aspartate aminotransferase, lactate dehydrogenase versus control group | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory | |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | increased for lead shot | relative kidney weights versus controls | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | reduced @ 10 ppm Se, 10 ppm Se + 10 ppm Hg | hematocrit and hemoglobin values versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory | |
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | increased @ 10 ppm Hg + 10 ppm Se | plasma glucose concentrations versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | decreased with Pb; no effect with Fe or Bi | body weight, gonad weight, hematocrit versus controls | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | increased with Pb; no effect with Fe or Bi | gizzard and kidney weight versus controls | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CYANOFENPHOS | increased (30% @ 10 mg leptophos/kg/d; 10% @ 0.5 mg cyanofenphos/kg/d; 0% @ 1.0 mg cyanofenphos/kg/d; 20% @ 2.0 mg cyanofenphos/kg/d ;60% @ 4.0 mg cyanofenphos/kg/d; 100% @ 8.0 mg cyanofenphos/kg/d | mortality versus controls) | Both Male and Female | Juvenile | 10 | laboratory | Toxicity Factor Datasets | 1 week | Laboratory |
CYANOFENPHOS | decreased @ 2.0, 4.0 mg/kg/d | bw versus controls | Both Male and Female | Juvenile | 10 | laboratory | Toxicity Factor Datasets | 1 week | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decreased @ 5 uL/egg | embryonic weight (females) and crown rump length (both sexes) | Both Male and Female | Hatchling | 65 eggs/group | Toxicity Factor Datasets | 3 days | Laboratory | |
CRUDE OILS | decreased @ 1, 5 uL/egg | bill length of both sexes | Both Male and Female | Hatchling | 65 eggs/group | Toxicity Factor Datasets | 3 days | Laboratory | |
CRUDE OILS | decreased to 65% @ 1 uL/egg); 9% @ 5 uL/egg | embryo survival to 18 days | Both Male and Female | Embryo | 65 eggs/group | Toxicity Factor Datasets | 3 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ENDOSULFAN | 7.89 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 30 days | Laboratory | |
ENDOSULFAN | 34.4 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | increased @ 30 ppm | liver protein concentration versus controls | Both Male and Female | Juvenile | 5-15 per group | Toxicity Factor Datasets | 75 days | Laboratory | |
DIELDRIN | increased @ 10, 30 ppm | liver DNA content versus controls | Male | Both Adults and Juveniles | 5-15 per group | Toxicity Factor Datasets | 75 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
MEXACARBATE | 3.0 mg/kg | LD50 | Both Male and Female | Not Reported | 12 | Toxicity Factor Datasets | 3 - 5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD ACETATE | decreased | ALAD enzyme activity versus controls | Male | Adult | 10 | Toxicity Factor Datasets | Laboratory | |
LEAD ACETATE | increased | iron concentration in liver versus controls | Male | Adult | 10 (controls); 30 (treated) | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (Technical Grade Mixture) | no effect | fertility, hatchability and duckling weight | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory | |
DDT (4,4'-) | no effect | fertility, hatchability and duckling weight | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
RADIONUCLIDES | see citation | table of mean concentrations of 6 radionuclides (238Pu, 239Pu, 241Am, 242Cm, 244Cm, 90Sr) in 6 mallard tissue types | Not Reported | Adult | 7-15 | leaching ponds, Test Reactor Area, Idaho National Engineering Laboratory | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1242 | decrease @ 150 ppm | body weight at 6, 8 and 12 wks of treatment | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1242 | no effect @ 150 ppm | embryo mortality, # infertile eggs/clutch or # eggs hatched/clutch | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DICOFOL | increase @ 100 ug/g | incidence of cracked and soft shelled eggs | Female | Adult | 4-8/dose | Toxicity Factor Datasets | Laboratory | |
DICOFOL | no effect | egg production during study period | Female | Adult | 4-8/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease | plasma prolactin levels during oviposition, early incubation and post-natal care | Female | Adult | 5-12/dose | Toxicity Factor Datasets | 10 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | behavior of offspring; latency in response to approach a maternal call and distance travelled from a frightening stimulus | Female | Adult | 4 adults/dose; 141-175 offspring/dose | Toxicity Factor Datasets | 10 mo | Laboratory | |
DDE (4,4'-) | 0.021 - 0.028 ppm wet wt @ 0 ppm; 5.8 (0.32 SE; range 4.28-7.23) ppm wet wt @ 3 ppm | mean and range of DDE egg concentrations | Female | Adult | 8 eggs/dose | Toxicity Factor Datasets | 10 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 200.7 (coeff. of variation 22.3%) | 5 day dietary LC50 | Not Reported | Juvenile | 8-10/dose | Toxicity Factor Datasets | 5 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PARATHION | 9% @ 1 mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 6/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory | |
FENTHION | 67% @ 2.2 mg/L | percent mortality | Not Reported | Juvenile | 6/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | decreased @ all doses | body weight gain by 8 days compared with controls | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 7 d | Laboratory | |
DDT (4,4'-) | 1550 ppm | 5 day dietary LC50 | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 7 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIAZINON | 74 (day 3), 79 (day 8) lb/acre LC50 | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PARATHION | 4/36 | mortality incidence by 20 hrs post-dose | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEPTOPHOS | decreased @ all doses | activity of brain and plasma cholinesterase, and brain neurotoxic esterase compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254, DDE (4,4'-) | no effect | food consumption rate (181 g/d) compared to control (173 g/d) | Female | Adult | 10/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | egg weight, length or breadth, compared to control | Female | Adult | 21-25/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | California Counties | Lab |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased @ 2 #four shot | spleen plaque forming cell counts, % packed cell volume versus controls | Both Male and Female | Adult | 16 (2 #four shot) 63 (field exposure) |
Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EPN | decreased @ 36 (cholineserase only), 108 ug/g | plasma alkaline phosphatase, aspartate aminotransferase, cholinesterase activities, and uric acid | Not Reported | Embryo | 12/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | lead only: 3.53 (+/- 1.43); lead-iron: 1.42 (+/- 0.65) ppm, wet wt | lead concentration in kidneys (mean +/- SE) | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD NITRATE | decreased @ 25 ppm/3 wks, 5 ppm/12 wks | delta-aminolevulinic acid dehydratase activity in blood versus controls | Male | Adult | 20/dose; 5/dose x time group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FUEL OILS | decrease @ 5, 10, 20, 50 ul | 6-day % survival of mallard embryos from eggs treated on the 8th day of incubation | Not Reported | Embryo | 50/dose | Toxicity Factor Datasets | 8d of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | kidney Cu concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 5.7 ppm (whole blood); 6.2 ppm (liver); 2.4 ppm (spleen) @ 300 mg/kg body weight | lead concentrations in tissues, 96 hr after exposure to lead in ducklings receiving vitamin E | Not Reported | Juvenile | 5/dose | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LINDANE | decrease @ 20 mg/kg 7x and 3x/wk | egg production and vitellogenin concentration in plasma, liver and ovary | Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | decreased | body weight compared to controls | Both Male and Female | Adult | 24 pairs/dose | Toxicity Factor Datasets | 7 and 11 months old | Laboratory |
Clapper Rail (Rallus longirostris)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDT (4,4'-) | 42.9 ppm | mean residue concentration in brains of birds that died | Male | Juvenile | 7 birds | Toxicity Factor Datasets | Laboratory | |
DDD (4,4'-), DDT (4,4'-) | 44.6 ppm | mean residue concentration in brains of birds that died | Female | Juvenile | 4 birds | Toxicity Factor Datasets | Laboratory |
Western Grebe (Aechmophorus occidentalis)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | California Counties |
---|---|---|---|---|---|---|---|---|
MERCURY COMPOUNDS | 0.001 (Clear Lake), 0.16 (Tule Lake) | productivity (young to adult ratios) at study locations | Not Reported | Adult | 13 birds, Clear Lake; 5 birds, Tule Lake | Clear Lake, Tule Lake | Toxicity Factor Datasets | Lake, Siskiyou |
Double-crested Cormorant (Phalacrocorax auritus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
POLYCHLORINATED BIPHENYLS | increased at 1606 ng/kg | total hepatic cytochrome P450 content | Not Reported | Hatchling | 5-12 eggs/dose | Saskatchewan, British Columbia, Lake Ontario | Toxicity Factor Datasets | CANADA |
POLYCHLORINATED BIPHENYLS | increased at 1606 ng/kg | hepatic EROD activity | Not Reported | Hatchling | 5-12 eggs/dose | Saskatchewan, British Columbia, Lake Ontario | Toxicity Factor Datasets | CANADA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
CADMIUM (elemental), MERCURY (elemental) | no correlation | correlation of mean metallothionein concentration (13.2-24.4 ug/g tissue) and metal concentrations in kidneys | Not Reported | Both Adults and Juveniles | 24 birds | Heron Is., Manawagonish Is., Ile aux pommes | Toxicity Factor Datasets | CANADA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | 47.5 pg/g bw gained (wet wt) | pg TCDD equivalents accumulated per gram of body weight gained (from eggs to largest chicks) | Not Reported | Nestling | 20 chicks | St. Martin's Shoal, Lake Huron | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | increased @ all doses | hepatic EROD activity in treated embryos versus controls | Not Reported | Embryo | 83-86 eggs/treatment | Lake Winnipegosis, Manitoba | Toxicity Factor Datasets | Laboratory |
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | increased @ all doses | hepatic EROD activity in treated embryos versus controls | Not Reported | Embryo | 83-86 eggs/treatment | Lake Winnipegosis, Manitoba | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
POLYCHLORINATED BIPHENYLS | positive correlation | correlation of embryo mortality with TCDD equivalents in eggs | Not Reported | Embryo | 11 colonies @ 25-50 nests/colony | Great Lakes | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
POLYCHLORINATED DIBENZO-P-DIOXINS | increased | P-450-dependent arachidonic acid metabolism by liver microsomes | Not Reported | Embryo | 3 | Toxicity Factor Datasets | 1 day | Laboratory |
Least Tern (Sterna antillarum)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), POLYCHLORINATED BIPHENYLS | 7% decrease | eggshell thickness compared with pre-1947 reference eggs | Female | Adult | 20 eggs | Cape Romain National Wildlife Refuge | Toxicity Factor Datasets |