Effects of mercury and selenium on glutathione metabolism and oxidative stress in mallards

Author(s)

Hoffman, David J., and Gary H. Heinz

Year

Thu, 01/01/1998 - 12:00

Article Title

Effects of mercury and selenium on glutathione metabolism and oxidative stress in mallards

Volume

Issue

Pages

161-166

Start Page Number

161

Final Page

166

Review

Datapoints

Displaying 1 - 10 of 10 datapoints.

Species: Mallard duck (Anas platyrhynchos)
Chemical	Toxicity Endpoint Type	Endpoint Description	Endpoint Value	Sample Size	Life Cycle Stage	Study Duration	Type
METHYLMERCURY CHLORIDE, SELENOMETHIONINE	TOX-Non-Repro-Sublethal - cellular/biochemical effects	hematocrit and hemoglobin values versus controls	reduced @ 10 ppm Se, 10 ppm Se + 10 ppm Hg	12/treatment	Adult	April 1-June 16	Toxicity Factor Datasets
METHYLMERCURY CHLORIDE, SELENOMETHIONINE	TOX-Non-Repro-Sublethal - cellular/biochemical effects	plasma glucose concentrations versus controls	increased @ 10 ppm Hg + 10 ppm Se	12/treatment	Adult	April 1-June 16	Toxicity Factor Datasets
METHYLMERCURY CHLORIDE, SELENOMETHIONINE	TOX-Non-Repro-Sublethal - cellular/biochemical effects	plasma phosphorus concentrations versus controls	decreased @ 10 ppm Se, 10 ppm Hg, 10 ppm Hg + 10 ppm Se	12/treatment	Adult	April 1-June 16	Toxicity Factor Datasets
METHYLMERCURY CHLORIDE, SELENOMETHIONINE	TOX-Non-Repro-Sublethal - cellular/biochemical effects	glutathione peroxidase activity (plasma and liver) and glucose-6-phosphate dehydrogenase (liver and brain) versus controls	decreased @ 10 ppm Hg	12/treatment	Adult	April 1-June 16	Toxicity Factor Datasets
METHYLMERCURY CHLORIDE, SELENOMETHIONINE	TOX-Non-Repro-Sublethal - cellular/biochemical effects	hepatic GSSG reductase activity versus controls	increased @ 10 ppm Se	12/treatment	Adult	April 1-June 16	Toxicity Factor Datasets
METHYLMERCURY CHLORIDE, SELENOMETHIONINE	TOX-Non-Repro-Sublethal - cellular/biochemical effects	oxidized glutathione (GSSG) level versus controls	increased @ 10 ppm Hg	12/treatment	Adult	April 1-June 16	Toxicity Factor Datasets
METHYLMERCURY CHLORIDE, SELENOMETHIONINE	TOX-Non-Repro-Sublethal - cellular/biochemical effects	protein-bound sulfhydryl in liver versus controls	reduced @ 10 ppm Hg, 10 ppm Hg + 10 ppm Se	12/treatment	Adult	April 1-June 16	Toxicity Factor Datasets
METHYLMERCURY CHLORIDE, SELENOMETHIONINE	TOX-Non-Repro-Sublethal - cellular/biochemical effects	thiobarbituric acid-reactive substances in brain versus controls	increased @ 10 ppm Hg, 10 ppm Se, 10 ppm Hg + 10 ppm Se	12/treatment	Adult	April 1-June 16	Toxicity Factor Datasets
METHYLMERCURY CHLORIDE, SELENOMETHIONINE	TOX-EXP IND - accumulation	mean (SE) wet wt Se concentrations in brain	3.4(0.22) ppm @ 10 ppm Se; 5.2(0.44) ppm @ 10 ppm Hg + 10 ppm Se	12/treatment	Adult	April 1-June 16	Toxicity Factor Datasets
METHYLMERCURY CHLORIDE, SELENOMETHIONINE	TOX-EXP IND - accumulation	mean (SE) wet wt Hg concentrations in brain	17.9(1.06) ppm @ 10 ppm Hg; 14.1(0.74) ppm @ 10 ppm Hg + 10 ppm Se	12/treatment	Adult	April 1-June 16	Toxicity Factor Datasets

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