Effects of 3,3',4,4',5-pentachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin injected into the yolks of double-crested cormorant (Phalacrocorax auritus) eggs prior to incubation

Author(s)
Powell, Debra, Richard J. Aulerich, John C. Meadows, Don E. Tillitt, Mary E. Kelly, Kenneth L. Stromborg, Mark J. Melancon, Scott D. Fitzgerald, and Steven J. Bursian
Year
Article Title
Effects of 3,3',4,4',5-pentachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin injected into the yolks of double-crested cormorant (Phalacrocorax auritus) eggs prior to incubation
Volume
17
Issue
10
Pages
2035-2040
Start Page Number
2035
Final Page
2040
Review

Datapoints

Displaying 1 - 10 of 10 datapoints.
Species: Double-crested Cormorant (Phalacrocorax auritus)
Chemical Toxicity Endpoint Type Endpoint Description Endpoint Value Sample Size Life Cycle Stage Study Duration Specific Location Type
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) TOX-MORT - dose-response data mortality in treated embryos versus controls increased @ 5.4, 10.7, 11.7 ug/kg egg 83-86 eggs/treatment Embryo 26-28 d Lake Winnipegosis, Manitoba Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) TOX-MORT - dose-response data mortality in treated embryos versus controls increased @ 175, 349, 698 ug/kg egg 83-86 eggs/treatment Embryo 26-28 d Lake Winnipegosis, Manitoba Toxicity Factor Datasets
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) TOX-MORT - toxicity benchmarks LD50 (95% confidence limits) 4.0 ug/kg egg (0.8-7.2) 83-86 eggs/treatment Embryo 26-28 d Lake Winnipegosis, Manitoba Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) TOX-MORT - toxicity benchmarks LD50 (95% confidence limits) 177 ug/kg egg (77-264) 83-86 eggs/treatment Embryo 26-28 d Lake Winnipegosis, Manitoba Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) TOX-REPRO - development incidence of developmental abnormalities, edema, body weight effects, spleen or gonad histopathologic anomalies, or sex ratio in treated embryos versus controls no effect 83-86 eggs/treatment Embryo 26-28 d Lake Winnipegosis, Manitoba Toxicity Factor Datasets
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) TOX-REPRO - development incidence of developmental abnormalities, edema, body weight effects, spleen or gonad histopathologic anomalies, or sex ratio in treated embryos versus controls no effect 83-86 eggs/treatment Embryo 26-28 d Lake Winnipegosis, Manitoba Toxicity Factor Datasets
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) TOX-REPRO - development hepatic EROD activity in treated embryos versus controls increased @ all doses 83-86 eggs/treatment Embryo 26-28 d Lake Winnipegosis, Manitoba Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) TOX-REPRO - development hepatic EROD activity in treated embryos versus controls increased @ all doses 83-86 eggs/treatment Embryo 26-28 d Lake Winnipegosis, Manitoba Toxicity Factor Datasets
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) TOX-REPRO - development spleen weights in treated embryos versus controls decreased @ 349 ug/kg egg 83-86 eggs/treatment Embryo 26-28 d Lake Winnipegosis, Manitoba Toxicity Factor Datasets
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) TOX-REPRO - development spleen weights in treated embryos versus controls decreased @ 5.4, 11.7 ug/kg egg 83-86 eggs/treatment Embryo 26-28 d Lake Winnipegosis, Manitoba Toxicity Factor Datasets

Comment

Please let us know if the information on this page is helpful for you. Enter your comment and leave your email address if you would like to receive a response. Thank you!
OEHHA is subject to the California Public Records Act and other laws that require the release of certain information upon request. If you provide comments, please be aware that your name, address and e-mail may be available to third parties. In addition, all public comments will be posted on our web site upon the close of the comment period.
OEHHA California Office of Environmental Health Hazard Assessment