Aquatic birds
Western Grebe (Aechmophorus occidentalis)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 61.5 ppm DDE, 5.2 ppm DDD, wet wt | mean concentration in visceral fat | Not Reported | Adult | 18 birds | Bear River Migratory Bird Refuge | Toxicity Factor Datasets |
DDE (4,4'-) | 0.55 ppm DDE, 0.07 ppm DDD, wet wt | mean concentration in blood | Not Reported | Adult | 16 birds | Bear River Migratory Bird Refuge | Toxicity Factor Datasets |
Brown Pelican (Pelecanus occidentalis)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 3 ug/g | level in eggs associated with impaired reproductive success (successful nests fledged at least one chick) | Both Male and Female | Juvenile | 156 eggs | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
FUEL OILS | decrease | hatching success (proportion of eggs hatched per clutch) of oiled versus control eggs | Not Reported | Embryo | 61-205 eggs | Cape Fear River | Toxicity Factor Datasets |
Double-crested Cormorant (Phalacrocorax auritus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), POLYCHLORINATED BIPHENYLS | negative correlation | correlation of egg concentration of DDE and est. PCB's and shell thickness and weight | Female | Adult | 35 eggs | Toxicity Factor Datasets | CANADA | |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), POLYCHLORINATED BIPHENYLS | decreased 8.3% compared with pre-1940 reference measurements | eggshell thickness | Female | Adult | 35 eggs | Toxicity Factor Datasets | CANADA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific |
---|---|---|---|---|---|---|---|---|
MERCURY (elemental), POLYCHLORINATED BIPHENYLS | 0.24 ppm wet wt PCBs | concentration in carcass | Not Reported | Juvenile | 5 birds | Lake Pointsett, Dry Lake | Toxicity Factor Datasets | 2-4 wks old |
MERCURY (elemental), POLYCHLORINATED BIPHENYLS | 14 | Ratio of concentration in carcass (0.64 ppm wet wt mercury) to dietary concentration (fish) | Not Reported | Adult | 10 carcasses | Lake Pointsett, Dry Lake | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | 31.3 | mean biomagnification factor for eggs from forage fish | Female | Adult | 12 eggs/site x 5 sites | Toxicity Factor Datasets | |
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | 162.4 pg/g bw gained (wet wt) | pg TCDD equivalents accumulated per gram of body weight gained (from eggs to largest chicks) | Not Reported | Nestling | 20 chicks | Green Bay, Lake Michigan | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | increased @ 175, 349, 698 ug/kg egg | mortality in treated embryos versus controls | Not Reported | Embryo | 83-86 eggs/treatment | Lake Winnipegosis, Manitoba | Toxicity Factor Datasets | Laboratory |
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | 4.0 ug/kg egg (0.8-7.2) | LD50 (95% confidence limits) | Not Reported | Embryo | 83-86 eggs/treatment | Lake Winnipegosis, Manitoba | Toxicity Factor Datasets | Laboratory |
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 17% decrease | serum calcium versus controls | Female | Adult | 6 hens; 45 total eggs | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | no effect | serum calcium after PTH injection versus controls | Female | Adult | 6 hens; 45 total eggs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Condition |
---|---|---|---|---|---|---|---|---|
DIAZINON | decreased (84%) | percent inhibition of post-mortem brain cholinesterase activity compared to control | Not Reported | Juvenile | 5 ducks | Toxicity Factor Datasets | dead | |
BENDIOCARB | decreased (73%) | percent inhibition of post-mortem brain cholinesterase activity compared to control | Not Reported | Adult | 4 ducks | Toxicity Factor Datasets | dead |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | progeny growth (average body weights) at hatch to 6 wks of age | Both Male and Female | Juvenile | 5 trios (2F, 1M adults)/dose | Toxicity Factor Datasets | Laboratory | |
PARATHION | no effect | egg production and fertility, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-L-methionine or seleno-D,L-methionine | hatchability versus controls | Both Male and Female | Both Adults and Juveniles | 15 pairs/treatment group, 10 pairs/control group | Toxicity Factor Datasets | Laboratory | |
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-L-methionine | duckling survival compared to controls | Both Male and Female | Adult | 15 pairs/treatment group, 10 pairs/control group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 165 ug/g diet (100 - 224 ug/g, 95% CI) | 96 hr LC50 | Not Reported | Juvenile | 10/dose | Toxicity Factor Datasets | 1 - 25 d | Laboratory | |
DIELDRIN | 29.5 ug/g diet (14 - 28 ug/g, 95% CI) | 24-d LC50 | Not Reported | Juvenile | 10/dose | Toxicity Factor Datasets | 1 - 25 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | ST = 0.986 - 0.060C | regression equation relating shell thickness (mm) to log10 yolk concentration (C, ug/g); r2=0.54 | Female | Adult | 63 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | no effect | mean daily food consumption rate (166.4 g food/kg body weight) | Female | Adult | 5-10/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | increase @ 100-200 ug/g | estradiol metabolism and cytochrome P450 concentration | Female | Adult | 4/dose/sampling time | Toxicity Factor Datasets | 80 d at initiation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
TRICHLOROPHENOXYACETIC ACID (2,4,5-) | 44 lbs AI/acre for exposure of 3d embryo; 44 lbs AI/acre for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | Toxicity Factor Datasets | 3 or 8d of development | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
MALATHION | 0% @ 5 mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory | |
MALATHION | 90.6% @ 5 mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | decreased @ all doses | body weight compared with controls | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PARATHION | decreased @ 0.75, 7.5 (aqueous) or 0.8 (oil) lb/acre | embryo weight by day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
MALATHION | increased @ 125 lb/acre | cumulative mortality by day 18 compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FENSULFOTHION | 48.9% (7.6 SE) | brain cholinesterase inhibition compared with controls | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
FONOFOS | 67.1% (4.9 SE) | brain cholinesterase inhibition compared with controls | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EPN | decreased @ 90, 270 pmm | plasma alkaline phosphatase activity compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
LEPTOPHOS | decreased @ 270, 540 ppm | body weight compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Condition | Lab |
---|---|---|---|---|---|---|---|---|---|
LINDANE | serum (0.20); fat (0.68); muscle (0.30); kidney (0.23); liver (0.14); brain (0.11) ppm @ 20 mg/kg 3x/wk | mean lindane residue levels | Female | Adult | 5/dose | Toxicity Factor Datasets | laying | Laboratory | |
LINDANE | serum (0.50); fat (1.14); muscle (0.82); kidney (0.28); liver (0.21); brain (0.13) ppm @ 20 mg/kg 7x/wk | mean lindane residue levels | Female | Adult | 5/dose | Toxicity Factor Datasets | laying | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase @ 2-15 ul/egg | percent mortality versus controls | Both Male and Female | Embryo | 100 eggs/dose | Toxicity Factor Datasets | days 2-18 of incubation | Laboratory | |
CRUDE OILS | increase @ 2-15 ul/egg | incidence of survivors with abnormalities versus controls | Both Male and Female | Embryo | 100 eggs/dose | Toxicity Factor Datasets | days 2-18 of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | California Counties | Lab |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased @ 2 #four shot | mortality versus controls | Both Male and Female | Adult | 12 (control); 16 (lab); 63 (field) | Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | Laboratory |
LEAD (elemental) | decreased @ 931,000 shot/acre or 2 #four pellets | spleen weight and total white blood cell counts versus controls | Both Male and Female | Adult | 12 (control); 16 (lab); 63 (field) | Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD NITRATE | decreased @ 5 ppm (8 d exposure) | mean percentage weight gain versus controls | Not Reported | Juvenile | 26-28/group | Toxicity Factor Datasets | 9 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | lead only: 112.27 (+/- 44.27); lead-iron: 32.65 (+/- 16.58) ppm, wet wt | lead concentration in bone (mean +/- SE) | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
LEAD (elemental) | lead only: 10.22 (+/- 1.46); lead-iron: 3.38 (+/- 0.56) ppm, wet wt | lead concentration in bone (mean +/- SE) | Male | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ACETONE | decreased @ 100% solution, incubation days 3 or 8 exposure | embryo weight and length by incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | 3 or 8 days of incubation (time of treatment) | Laboratory | |
ACETONE | decreased @ 100% solution, incubation days 3 or 8 exposure | embryo survival through incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | 3 or 8 days of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
HEPTACHLOR | decreased @ 1000 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | Toxicity Factor Datasets | Laboratory | |
ARSENITE, SODIUM | decreased @ 100 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | decreased @ 200 ppm | weight of testes versus controls | Male | Adult | 5 birds | Toxicity Factor Datasets | first year | Laboratory | |
CADMIUM CHLORIDE | increased @ 200 ppm | incidence of kidney lesions versus controls | Both Male and Female | Adult | 10 birds | Toxicity Factor Datasets | first year | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM | increased @ 10, 100, 300 ppm | incidence of altered brain and liver biochemistry | Both Male and Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory | |
ARSENATE, SODIUM | increased @ 100 ppm ( 0.3 ppm, dry wt), 300 ppm (1.3 ppm, dry wt) | arsenic concentrations in liver (geometric means in parentheses) | Both Male and Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | increased @ 12.5, 50, 200, 800 ppm diet | kidney, blood, liver, and feather concentrations of Ni compared to controls | Both Male and Female | Adult | 6 pairs/group | Toxicity Factor Datasets | Laboratory | |
NICKEL SULFATE | 1.94 (kidney), 0.52 (liver), 0.139 (blood), 68.06 (feathers) ppm, wet wt | mean tissue concentrations @ 800 ppm Ni in diet | Both Male and Female | Adult | 6 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SALINE WATER | decreased @ 4000 or 7720 umhos/cm | body weight by day 14 or 16 versus controls | Not Reported | Juvenile | 10 birds/group | Toxicity Factor Datasets | 2 d | Laboratory | |
SALINE WATER | increased | plasma protein levels; serum osmolality; salt, kidney and adrenal gland size versus controls | Not Reported | Juvenile | 10 birds/group | Toxicity Factor Datasets | 2 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE | decreased @ 27, 90 ug Hg | embryo crown to rump length by day 18 of incubation versus controls | Both Male and Female | Embryo | 80 eggs/group | Toxicity Factor Datasets | incubation day 3 | Laboratory | |
METHYLMERCURY CHLORIDE | decreased @ 9, 27, 90 ug Hg | % survival by day 18 of incubation versus controls | Both Male and Female | Embryo | 80 eggs/group | Toxicity Factor Datasets | incubation day 3 | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased @ 20, 40 ppm | hepatic malondialdehyde concentrations versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
SELENITE, SODIUM | increased @ 40 ppm | hepatic malondialdehyde concentrations versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | increased @ 450 ppm | plasma uric acid, adrenal corticosterone levels | Not Reported | Adult | 12 birds/group | Toxicity Factor Datasets | 1 yr | Laboratory | |
CADMIUM CHLORIDE | no effect | food consumption compared to controls | Not Reported | Adult | 12 birds/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | decreased @ 60 ppm Se | body, liver, and spleen weight; tarsus length versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
BORIC ACID, SELENOMETHIONINE | decreased @ 60 ppm Se (100% mort.) | survival versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
TOXAPHENE (POLYCHLORINATED CAMPHENES) | 130 (80.4-210), 30.8 (23.3-40.6), 70.7 (37.6-133) | LD50's determined at ages 36 hr, 7 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hr, 7 d, 30 d, or 6 mos | Laboratory | |
CHLORPYRIFOS | 83.3 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 6 mos | Laboratory | |
MEXACARBATE | 3.16 (2.17-4.61), 4.11 (2.70-6.26), 3.61 (2.37-5.49), 3.23 (2.72-3.85), 2.72(2.28-3.23) | LD50's determined at ages 48 hr, 7 d, 14 d, 30 d and 60 d, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hr, 7 d, 30 d, or 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | no effect | egg production versus controls | Female | Adult | 20 females/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 80.7 ug/g lipid, 30.1 ug/g skin, 1.6 ug/g brain, 4.1 ug/g liver, 1.8 ug/g muscle at 49.3 ug/g food | mean of day 5, 7, 8 (approx. steady state) tissue concentrations | Not Reported | Juvenile | 6 | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase | body temperature at an ambient temperature of -17C, compared to control | Not Reported | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
BORIC ACID | no effect | eggshell thickness and Ratcliffe index of eggshell quality | Female | Adult | 15/dose | Toxicity Factor Datasets | Laboratory | |
BORIC ACID | increase @ 1000 ppm | % embryo mortality (day 15 to hatch) and duckling mortality (hatch to day 7) | Both Male and Female | Both Adults and Juveniles | 11-23/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase | plasma triglyceride and sodium concentrations, compared to control (based on treatment means at 3, 6, 9 wks) | Not Reported | Juvenile | 25/dose | Toxicity Factor Datasets | 4 d | Laboratory | |
CRUDE OILS | decrease | hematocrit and plasma cholesterol concentration, compared to control (based on treatment means at 3, 6, 9 wks) | Not Reported | Juvenile | 25/dose | Toxicity Factor Datasets | 4 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SEWAGE SLUDGE | no effect | immune defenses; resistance to Pasturella multocida estimated by % mortality 14 d after challenge, compared to controls | Male | Adult | 10/dose | Toxicity Factor Datasets | Laboratory | |
SEWAGE SLUDGE | increase @ 20% Milorganite or Metrogro | liver cadmium concentrations; compared to controls | Male | Adult | 10/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PHOSPHORUS (YELLOW OR WHITE) | increased @ 235.0, 484.2, 972.0 ug/g (nominal concentrations) | incidence of clinical signs versus controls | Both Male and Female | Adult | 5 males, 5 females/dose | Toxicity Factor Datasets | Laboratory | |
PHOSPHORUS (YELLOW OR WHITE) | decreased @ 484.2, 972.0 ug/g (nominal concentrations) | food consumption during first week of treatment versus controls | Both Male and Female | Adult | 5 males, 5 females/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | 23.3(1.0) ppm | mean(SE) wet wt concentrations of Aroclor 1254 in eggs | Not Reported | Embryo | 19 eggs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | decreased @ 40 and 80 ppm | body weight over exposure period versus controls | Male | Adult | 21/dose | Toxicity Factor Datasets | 1 yr | Laboratory | |
SELENOMETHIONINE | increased in birds that died | incidence of macroscopic abnormalities versus controls | Male | Adult | 21/dose | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | decreased @ 900 ppm B | total SH, liver protein, sorbitol dehyrogenase versus controls | Both Male and Female | Juvenile | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory | |
BORIC ACID, SELENOMETHIONINE | reduced @ 900 ppm B | body weight and growth at 0, 7,and 14 days post-hatch versus controls | Both Male and Female | Juvenile | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | increased @ 642 and 1284 ug/g | protoporphyrin versus controls | Male | Adult | 10/ Pb treatment; 5/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | reduced @ 1284 ug/g | hematocrit versus controls | Male | Adult | 10/ Pb treatment; 5/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | increased for lead shot | incidence of clinical signs versus other groups | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | increased @ 10 ppm Se, 10 ppm Hg, 10 ppm Hg + 10 ppm Se | incidence of deformities in embryos that died (1 wk or older) versus controls | Both Male and Female | Both Adults and Juveniles | 12/group | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS | 145(6.0) ppm, kidneys; 1086(72) ppm, liver; 32.1(6.3) ppm, gonads | mean(SE) wet wt Fe concentration in organs of Fe-treated birds | Both Male and Female | Adult | 20 males, 20 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased | blood ALAD enzyme activity after 1,2, or 3 months versus pre-dose controls | Both Male and Female | Adult | 20 per sex | laboratory | Toxicity Factor Datasets | 8 months | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | liver: C = 7.4(1-e^-0.382t) muscle: C = 8.0(1-e^-0.037t) |
selenium accumulation equations | Both Male and Female | Adult | 3 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | bw versus controls | Both Male and Female | Juvenile | 9-25 per group | Toxicity Factor Datasets | 75 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDT (Technical Grade Mixture) | see citation | table of DDE, DDD and DDT residues in 21 tissues following varying times after application | Not Reported | Not Reported | 1-6/sample | Sandusky Bay, Port Clinton | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DICROTOPHOS | 101.8 (coeff. of variation = 21.6%) | 5 day dietary LC50 | Not Reported | Juvenile | 8-10/dose | Toxicity Factor Datasets | 5 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ASULAM | 10% @ 4000 mg/kg | percent mortality after 21 days | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 7 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EPN | decreased @ 12 ug/g (82%); 36 ug/g (77%); 108 ug/g (70%) | percent survival versus controls | Not Reported | Embryo | 10/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM, SELENOMETHIONINE | no effect | tarsus length, 10th primary length, heart weight versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | 0.51-0.54 ppm blood, 2.07-2.41 ppm kidney, 2.35-2.26 ppm liver, 0.74-0.97 ppm breast muscle, 0.47-0.51 ppm brain, 0.88 ppm eggs @ 0.5 ppm in diet | range of mean Hg (ppm wet-weight) concentrations in wild-strain males and females | Both Male and Female | Adult | 6-9 (9 breeding pairs/dose) | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase @ 1% and 3% | hepatic microsomal naphthalene metabolism (nmol/min/mg protein), compared to control, in adult females and in neonatal ducklings hatched from eggs laid by females (1% Prudhoe Bay dose level was not significantly different for neonates). | Female | Adult | 6 adults/dose; 5-20 neonates/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
GLYPHOSATE | increased @ 50, 90 percent | population density 2 years post-spray versus controls | Not Reported | Not Reported | 3-6 sample wetlands/treatment | near Lakota (48deg03'N, 98deg21'W) | Toxicity Factor Datasets |
Clapper Rail (Rallus longirostris)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | 1896 ppm | 5 day dietary LC50 | Female | Juvenile | 4 birds | Toxicity Factor Datasets | Laboratory |