Birds
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | decreased @ 900 ppm B | total SH, liver protein, sorbitol dehyrogenase versus controls | Both Male and Female | Juvenile | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory | |
BORIC ACID, SELENOMETHIONINE | reduced @ 900 ppm B | body weight and growth at 0, 7,and 14 days post-hatch versus controls | Both Male and Female | Juvenile | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | increased @ 642 and 1284 ug/g | protoporphyrin versus controls | Male | Adult | 10/ Pb treatment; 5/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | reduced @ 1284 ug/g | hematocrit versus controls | Male | Adult | 10/ Pb treatment; 5/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | increased for lead shot | incidence of clinical signs versus other groups | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory | |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | reduced for lead shot | body weight versus all other groups | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | increased @ 10 ppm Se, 10 ppm Hg, 10 ppm Hg + 10 ppm Se | incidence of deformities in embryos that died (1 wk or older) versus controls | Both Male and Female | Both Adults and Juveniles | 12/group | Toxicity Factor Datasets | 18 mo | Laboratory | |
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 7.6(0.26) ppm, egg, 6.0(0.31) ppm, fem. liver, 9.6(0.95) ppm, male liver @ 10 ppm Se; 9.3(0.85) ppm, egg, 9.2(1.61) ppm, female liver, 114(25.3) ppm, male liver @ 10 ppm Se + 10 ppm Hg | mean(SE) wet wt concentration of Se in egg and liver of treated birds | Both Male and Female | Adult | 12/group | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS | 145(6.0) ppm, kidneys; 1086(72) ppm, liver; 32.1(6.3) ppm, gonads | mean(SE) wet wt Fe concentration in organs of Fe-treated birds | Both Male and Female | Adult | 20 males, 20 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS | no effect | histopathological lesions in gonads, liver, kidneys versus controls | Both Male and Female | Adult | 20 males, 20 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased | blood ALAD enzyme activity after 1,2, or 3 months versus pre-dose controls | Both Male and Female | Adult | 20 per sex | laboratory | Toxicity Factor Datasets | 8 months | Laboratory |
LEAD (elemental) | increased | blood Pb concentrations versus pre-dose controls | Both Male and Female | Adult | 20 per sex | laboratory | Toxicity Factor Datasets | 8 months | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | liver: C = 7.4(1-e^-0.382t) muscle: C = 8.0(1-e^-0.037t) |
selenium accumulation equations | Both Male and Female | Adult | 3 | Toxicity Factor Datasets | Laboratory | |
SELENOMETHIONINE | liver: C = 7.4e^-0.037t muscle: C = 5.6e^-0.023t liver at peak body burden: C = 22.6e^-0.246t + 2.5 e^-0.008t muscle at peak body burden: C = 6.4e^-0.029t Loss phase for blood at peak body burden: C = 12.0e^-0.071t |
selenium depuration equations | Both Male and Female | Adult | 3 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | 83.3 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 6 mos | Laboratory | |
MEXACARBATE | 3.16 (2.17-4.61), 4.11 (2.70-6.26), 3.61 (2.37-5.49), 3.23 (2.72-3.85), 2.72(2.28-3.23) | LD50's determined at ages 48 hr, 7 d, 14 d, 30 d and 60 d, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hr, 7 d, 30 d, or 6 mos | Laboratory | |
ENDOSULFAN | 27.8 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hours | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | bw versus controls | Both Male and Female | Juvenile | 9-25 per group | Toxicity Factor Datasets | 75 days | Laboratory | |
DIELDRIN | increased @ 10 ppm (liver only), 30 ppm (brain only) | brain and liver weight to body weight ratios versus controls | Both Male and Female | Juvenile | 9-25 per group | Toxicity Factor Datasets | 75 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD ACETATE | decreased | % packed cell volume versus controls | Male | Adult | 10 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LINDANE | 18-21% decrease @ 20 mg/kg 7x or 3x/wk | eggshell thickness, compared to control | Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PARATHION | no effect | % hatchability, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-D,L-methionine, seleno-L-methionine, or selenized yeast | number of 6-day-old ducklings produced per female versus controls | Both Male and Female | Both Adults and Juveniles | 15 pairs/treatment group, 10 pairs/control group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 16.4 ug/g diet | 24-d LOAEL based on growth impairment | Not Reported | Juvenile | 10/dose | Toxicity Factor Datasets | 1 - 25 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase | length of reproductive cycle; due to prolonged phase of gonadal maturation | Female | Adult | 17 pairs/dose | Toxicity Factor Datasets | 10 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 36-67% decrease @ 10-1000 ppm | salt gland excretion volume, compared to controls | Male | Not Reported | 12/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 155.8 (coeff. of variation = 16.0%) | 5 day dietary LC50 | Not Reported | Juvenile | 8-10/dose | Toxicity Factor Datasets | 5 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ACEPHATE | 0% @ 5 mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ASULAM | decreased @ all doses | food consumption compared with controls | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 7 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
MALATHION | increased @ 125 lb/acre | cumulative mortality by day 18 compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FONOFOS | 67.1% (4.9 SE) | brain cholinesterase inhibition compared with controls | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEPTOPHOS | decreased @ 270, 540 ppm | body weight compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Condition | Lab |
---|---|---|---|---|---|---|---|---|---|
LINDANE | serum (0.50); fat (1.14); muscle (0.82); kidney (0.28); liver (0.21); brain (0.13) ppm @ 20 mg/kg 7x/wk | mean lindane residue levels | Female | Adult | 5/dose | Toxicity Factor Datasets | laying | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase @ 2-15 ul/egg | incidence of survivors with abnormalities versus controls | Both Male and Female | Embryo | 100 eggs/dose | Toxicity Factor Datasets | days 2-18 of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | California Counties | Lab |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased @ 931,000 shot/acre or 2 #four pellets | spleen weight and total white blood cell counts versus controls | Both Male and Female | Adult | 12 (control); 16 (lab); 63 (field) | Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EPN | decreased @ 12 ug/g (82%); 36 ug/g (77%); 108 ug/g (70%) | percent survival versus controls | Not Reported | Embryo | 10/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | lead only: 10.22 (+/- 1.46); lead-iron: 3.38 (+/- 0.56) ppm, wet wt | lead concentration in bone (mean +/- SE) | Male | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ACETONE | decreased @ 100% solution, incubation days 3 or 8 exposure | embryo survival through incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | 3 or 8 days of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ARSENITE, SODIUM | decreased @ 100 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | increased @ 200 ppm | incidence of kidney lesions versus controls | Both Male and Female | Adult | 10 birds | Toxicity Factor Datasets | first year | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM | increased @ 100 ppm ( 0.3 ppm, dry wt), 300 ppm (1.3 ppm, dry wt) | arsenic concentrations in liver (geometric means in parentheses) | Both Male and Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | 1.94 (kidney), 0.52 (liver), 0.139 (blood), 68.06 (feathers) ppm, wet wt | mean tissue concentrations @ 800 ppm Ni in diet | Both Male and Female | Adult | 6 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SALINE WATER | increased | plasma protein levels; serum osmolality; salt, kidney and adrenal gland size versus controls | Not Reported | Juvenile | 10 birds/group | Toxicity Factor Datasets | 2 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE | decreased @ 9, 27, 90 ug Hg | % survival by day 18 of incubation versus controls | Both Male and Female | Embryo | 80 eggs/group | Toxicity Factor Datasets | incubation day 3 | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM | increased @ 40 ppm | hepatic malondialdehyde concentrations versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | no effect | food consumption compared to controls | Not Reported | Adult | 12 birds/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | decreased @ 60 ppm Se (100% mort.) | survival versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM, SELENOMETHIONINE | no effect | tarsus length, 10th primary length, heart weight versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | 0.51-0.54 ppm blood, 2.07-2.41 ppm kidney, 2.35-2.26 ppm liver, 0.74-0.97 ppm breast muscle, 0.47-0.51 ppm brain, 0.88 ppm eggs @ 0.5 ppm in diet | range of mean Hg (ppm wet-weight) concentrations in wild-strain males and females | Both Male and Female | Adult | 6-9 (9 breeding pairs/dose) | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase @ 1% and 3% | hepatic microsomal naphthalene metabolism (nmol/min/mg protein), compared to control, in adult females and in neonatal ducklings hatched from eggs laid by females (1% Prudhoe Bay dose level was not significantly different for neonates). | Female | Adult | 6 adults/dose; 5-20 neonates/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
BORIC ACID | increase @ 1000 ppm | % embryo mortality (day 15 to hatch) and duckling mortality (hatch to day 7) | Both Male and Female | Both Adults and Juveniles | 11-23/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease | hematocrit and plasma cholesterol concentration, compared to control (based on treatment means at 3, 6, 9 wks) | Not Reported | Juvenile | 25/dose | Toxicity Factor Datasets | 4 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SEWAGE SLUDGE | increase @ 20% Milorganite or Metrogro | liver cadmium concentrations; compared to controls | Male | Adult | 10/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PHOSPHORUS (YELLOW OR WHITE) | decreased @ 484.2, 972.0 ug/g (nominal concentrations) | food consumption during first week of treatment versus controls | Both Male and Female | Adult | 5 males, 5 females/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
GLYPHOSATE | increased @ 50, 90 percent | population density 2 years post-spray versus controls | Not Reported | Not Reported | 3-6 sample wetlands/treatment | near Lakota (48deg03'N, 98deg21'W) | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased in birds that died | incidence of macroscopic abnormalities versus controls | Male | Adult | 21/dose | Toxicity Factor Datasets | 1 yr | Laboratory |
Clapper Rail (Rallus longirostris)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | 1896 ppm | 5 day dietary LC50 | Female | Juvenile | 4 birds | Toxicity Factor Datasets | Laboratory | |
DDD (4,4'-), DDT (4,4'-) | 13.3 ppm | mean residue concentration in brains of birds that survived | Male | Juvenile | 7 birds | Toxicity Factor Datasets | Laboratory |
Peregrine Falcon (Falco peregrinus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
POLYCHLORINATED BIPHENYLS | review | concentrations in eggs associated with reduced reproduction (various raptor species) | Not Reported | Adult | Not Reported | Toxicity Factor Datasets | Laboratory | |
HEPTACHLOR EPOXIDE | review | concentrations in brain associated with mortality (various raptor species) | Not Reported | Not Reported | Not Reported | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 16.8-24.9% | percent eggshell thinning compared with pre-1946 reference eggs | Female | Adult | 3-11 eggs/year | Colville, Yukon, Tanana Rivers | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Condition |
---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN | 48.0 (DDE), 3.35 (DDD), 1.02 (DDT), 1.45 (dieldrin) | mean concentrations of pesticides in eggs (ppm, dry weight) | Female | Adult | 2 eggs | Yukon River | Toxicity Factor Datasets | |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN | 622.0 (DDE), 25.4 (DDD), 25.3 (DDT), 6.20 (dieldrin) | mean concentrations of pesticides in fat (ppm, dry weight) | Both Male and Female | Adult | 4 birds | Yukon River | Toxicity Factor Datasets | breeding |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | productivity = 1.79 - 0.04(DDE) | linear regression of productivity (number of young fledged per site) and DDE concentrations in eggs | Both Male and Female | Adult | 9 eggs | Tasmania | Toxicity Factor Datasets | AUSTRALIA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), MERCURY COMPOUNDS, POLYCHLORINATED BIPHENYLS | 2.4-25.0 (DDE); 0.5-10.6 (PCBs); 0.2-4.2 (Hg) | residues in eggs (ppm, wet wt) | Female | Adult | 5 eggs (from 5 nests) | Gulf of California | Toxicity Factor Datasets | MEXICO |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | review | data correlating eggshell thinning and DDE concentrations in eggs | Female | Adult | Not Reported | Toxicity Factor Datasets | GLOBAL |
American Kestrel (Falco sparverius)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decrease at 125, 625 mg/kg bw (20-25%) | liver delta aminolevulinic acid dehydratase activity | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decrease | carbonic anhydrase activity of shell gland | Female | Adult | 8/group | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | no effect | calcium concentration in blood | Female | Adult | 8/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | 0.70 (0.20 SE) ppm (wet wt) | lead concentration in tibia | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | 232 (9 SE) ppm (wet wt) | DDE concentration in carcass | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
FENTHION | 1.4 mg/kg bw | LD50 | Both Male and Female | Adult | 5/group | Toxicity Factor Datasets | Laboratory | |
CARBOFURAN | 0.6 mg/kg bw (0.5-1.0 95% CI) | LD50 | Both Male and Female | Adult | 5/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | decreased | red blood cell delta aminolevulinic acid dehydratase activity (relative to control) | Both Male and Female | Both Adults and Juveniles | 33 | Coeur D'Alene River | Toxicity Factor Datasets |
LEAD COMPOUNDS | decreased | hematocrit | Both Male and Female | Juvenile | 30 | Coeur D'Alene River | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) | no effect | hepatic porphyrin levels | Female | Adult | 5-6/group | Toxicity Factor Datasets | 1 yr | Laboratory | |
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) | no effect | liver weight | Female | Adult | 5-6/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1248 | 5% decrease @ 3.0 ug/g | mean eggshell thickness | Female | Adult | 8 pairs/group | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1248 | 5.60 ug/g (1.15 SD), PCBs; 0.15 ug/g (0.05 SD), dieldrin; 0.15 ug/g (0.07 SD), DDE @ 3.0 ug/g | mean egg concentrations, wet wt | Female | Adult | 8 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PARAQUAT | decreased @ 25, 60 mg/kg | skeletal growth (humerus, femur, radius-ulna, tibia-fibula) | Not Reported | Juvenile | 11/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DICOFOL | increased @ 5 mg/kg bw | incidence of abnormal gonads in male offspring of dicofol-treated females versus controls | Male | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254, PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL), PCB 77 (3,3',4,4'-TETRACHLOROBIPHENYL) | increased with Aroclor 1254 | coproporphyrin levels in liver versus controls | Female | Adult | 4/treatment group | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1254, PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL), PCB 77 (3,3',4,4'-TETRACHLOROBIPHENYL) | increased with PCB 77 | liver ethoxyresorufin-O-deethylase activity versus controls | Female | Adult | 4/treatment group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|
LEAD (elemental) | 40% at 625 mg/kg bw | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, OXYCHLORDANE, POLYCHLORINATED BIPHENYLS | increased | occurence of wild birds dying diagnosed with organochlorine poisoning | Both Male and Female | Both Adults and Juveniles | 5 kestrels | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DICOFOL | increased | incidence of abnormal behavior in adult offspring of treated females | Both Male and Female | Adult | 10 pairs/group | Toxicity Factor Datasets | Laboratory |
Mourning Dove (Zenaida macroura)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 65.4-123.2 ug/g, dry wt | mean lead concentrations in femur (greater accumulation with mixed seed vs. pelleted diet) | Female | Adult | 12/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | 2.80-4.98 ug/g, dry wt | mean lead concentrations in liver (greater accumulation with mixed seed vs. pelleted diet) | Female | Adult | 12/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | high degree of lesions present | histological exam of acid-fast intranuclear inclusions of cells of kidney proximal convoluted tubules | Not Reported | Not Reported | 1 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | no effect | body weight | Male | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
TOXAPHENE (POLYCHLORINATED CAMPHENES) | 200-250 mg/kg | approximate median lethal dosage | Not Reported | Not Reported | 8 birds | Toxicity Factor Datasets | Laboratory |
Great Horned Owl (Bubo virginianus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
STRYCHNINE | increased | occurence (compared with pre-dose values) of uncoordinated movement, tremors, loss of perching ability and ability to stand on the ground | Not Reported | Adult | 1 bird | Toxicity Factor Datasets | Laboratory |
Loggerhead Shrike (Lanius ludovicianus)
Chemical | Endpoint Value | Location | Type | Lab |
---|---|---|---|---|
DIELDRIN | review | Toxicity Factor Datasets | Laboratory |
Song Sparrow (Melospiza melodia)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DIAZINON | 38% | mortality of eggs and nestlings (control 21 %) | Not Reported | Embryo, Nestling | 9 nests | Sherbrooke, Quebec | Toxicity Factor Datasets | CANADA |
Western Grebe (Aechmophorus occidentalis)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 6.6 ppm DDE, 1.3 ppm DDD, wet wt | mean concentration in whole eggs | Not Reported | Embryo | 40 eggs | Toxicity Factor Datasets |
Brown Pelican (Pelecanus occidentalis)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
ARSENIC COMPOUNDS, MERCURY COMPOUNDS, POLYCHLORINATED DIBENZO-P-DIOXINS, SELENIUM COMPOUNDS | no effect | half-peak coefficient of variation (HPCV) in DNA content vs. reference samples | Not Reported | Chick | 15 | Ferry Slip Island and South Pelican Island (33deg59'N,77deg57'W) | Toxicity Factor Datasets |
Double-crested Cormorant (Phalacrocorax auritus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), POLYCHLORINATED BIPHENYLS | no effect | shell thickness | Female | Adult | 10 eggs from 10 nests | OR coast | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
MERCURY (elemental), POLYCHLORINATED BIPHENYLS | 0.29 ppm wet wt mercury | mean concentration in eggs | Female | Adult | 5 eggs | Lake Pointsett, Dry Lake | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | 100.4 pg/g bw gained (wet wt) | pg TCDD equivalents accumulated per gram of body weight gained from egg to largest chick stage | Not Reported | Nestling | 20 chicks | Beaver Islands, Lake Michigan | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | 177 ug/kg egg (77-264) | LD50 (95% confidence limits) | Not Reported | Embryo | 83-86 eggs/treatment | Lake Winnipegosis, Manitoba | Toxicity Factor Datasets | Laboratory |