Birds
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | decreased @ 16, 32 ppm | hemoglobin concentration compared to controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory | |
SELENOMETHIONINE | increased @ 2 ppm or greater | plasma glutathione peroxidase activity versus controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DICROTOPHOS | 6.17 (3.33-11.4), 7.03 (5.30-9.31), 6.73 (5.53-8.19), 4.14 (3.33-5.16) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hr, 7 d, 30 d, or 6 mos | Laboratory | |
PARATHION | 1.65 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 30 days | Laboratory | |
FENSULFOTHION | 0.528, 0.747, 1.06 (0.868-1.29), 0.747 (0.588-0.949) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hr, 7 d, 30 d, or 6 mos | Laboratory | |
PARATHION | 2.34 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | decreased in 3rd generation | eggshell thickness versus controls | Female | Adult | 14 pairs/group | Toxicity Factor Datasets | Laboratory | |
METHYLMERCURY DICYANDIAMIDE | increased in 2nd generation | proportion of eggs laid outside nestbox | Female | Adult | 14 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PENTACHLOROPHENOL | 22.2 +/- 5.5 ug/g lipid, 30.7 +/- 10.3 ug/g liver, 11.0 +/- 0 ug/g muscle, 4.0 +/- 1.4 ug/g brain at 961 ug/g diet | mean +/- SD tissue concentrations at the reported LOAEL (development) | Not Reported | Juvenile | 4-6 | Toxicity Factor Datasets | 4 d | Laboratory | |
PENTACHLOROPHENOL | 12.2 +/- 2.3 ug/g lipid, 20.7 +/- 3.7 ug/g liver, 3.3 +/- 1.6 ug/g muscle, 2.6 +/- 1.5 ug/g brain at 423.2 ug/g diet | mean +/- SD tissue concentrations at the reported NOAEL (development) | Not Reported | Juvenile | 6-8 | Toxicity Factor Datasets | 4 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 38 ug/g wet weight egg (yolk + white), 1.20 ug/g wet weight egg shell gland mucosa @ 40 mg/kg | mean DDE concentrations | Female | Adult | 7-9 | Toxicity Factor Datasets | 1 yr | Laboratory | |
DDE (4,4'-) | 32% decrease @ 40 mg/kg | Ca2+-Mg2+ ATPase activity in eggshell gland mucosa homogenates, compared to controls | Female | Adult | Not Reported | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID | increase @ 1600 ppm | plasma calcium concentration (6-10% greater than controls) and brain acetylcholinestrase activity (umol/min/g) | Both Male and Female | Juvenile | 10 animals/pen; 3 pens/dose | Toxicity Factor Datasets | 1 d | Laboratory | |
BORIC ACID | 2 ug/g @ control; 4 ug/g @ 100 ppm; 5 ug/g @ 400 ppm; 51 ug/g @ 1600 ppm | boron accumulation in brain (geometric mean; ug/g dry weight) | Both Male and Female | Juvenile | 10 animals/pen; 3 pens/dose | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
COREXIT 9527 | no effect | body weight, compared to controls | Male | Adult | 6/dose | Toxicity Factor Datasets | Laboratory | |
FUEL OILS | increase @ 2.5, 4.0 ml/kg | susceptibility to Pasturella multocida estimated as % mortality 2-wks post-exposure to Pasturella multocida which was given on day 28 | Male | Adult | 9-32/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
POLYCYCLIC AROMATIC HYDROCARBONS (PAHs) | increase @ 0.2, 2.0 mg/kg egg | embryonic mortality, compared to controls | Not Reported | Embryo | 22/dose | Toxicity Factor Datasets | 5 d of incubation | Laboratory | |
BENZO[k]FLUORANTHENE | increase @ 0.2, 2.0 mg/kg egg | embryo mortality, compared to controls | Not Reported | Embryo | 20/dose | Toxicity Factor Datasets | 5 d of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PHOSPHORUS (YELLOW OR WHITE) | increased above 4.3 mg/kg bw | liver to body weight ratio versus controls | Not Reported | Adult | 4-5 birds/dose | Toxicity Factor Datasets | Laboratory | |
PHOSPHORUS (YELLOW OR WHITE) | positive relationship | relation between liver to body weight ratio and dose | Male | Adult | 4-5 birds/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | increased @ 250, 500 mg/kg bw | lymphocyte proliferation to PHA versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EMAMECTIN BENZOATE | 20 ppm diet | no-observed-effect concentration (NOEC), based on reduced feed consumption and weight gain | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 10 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | reduced @ 900 ppm B | egg weight, hatching success, egg fertility versus controls | Both Male and Female | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory | |
BORIC ACID, SELENOMETHIONINE | reduced @ 7 ppm Se | body weight versus controls | Female | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | increased @ 828 ug/g | occurrence of lead poisoning signs versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | 4.1(1.03) ppm in blood, 13(1.2) ppm in liver @ 954 ug/g, complete diet; 4.0(0.58) ppm in blood, 38(6.5) ppm in liver @ 869 ug/g, corn diet | mean (SE) wet wt Pb concentrations in blood and liver | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory | |
LEAD COMPOUNDS | increased @ all doses | protoporphyrin levels in blood versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | no effect | body weight versus controls | Both Male and Female | Adult | 12/group | Toxicity Factor Datasets | 18 mo | Laboratory | |
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | increased @ 10 ppm Hg | incidence of leg weakness versus controls | Male | Adult | 12/group | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 3.4(0.22) ppm @ 10 ppm Se; 5.2(0.44) ppm @ 10 ppm Hg + 10 ppm Se | mean (SE) wet wt Se concentrations in brain | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory | |
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 17.9(1.06) ppm @ 10 ppm Hg; 14.1(0.74) ppm @ 10 ppm Hg + 10 ppm Se | mean (SE) wet wt Hg concentrations in brain | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no effect with Fe or Bi | egg weight, eggshell thickness, fertility, hatchability versus controls | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no effect with Fe or Bi | histopathology of kidney, liver, testis, heart, lung versus controls | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased (60%) | blood ALAD activity versus controls | Male | Juvenile | 8 | Laboratory | Toxicity Factor Datasets | 6 months | Laboratory |
LEAD (elemental) | increased | blood protoporphyrin levels versus controls | Male | Juvenile | 8 | Laboratory | Toxicity Factor Datasets | 6 months | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | increased | % cracked eggs versus controls | Female | Hatchling | 666-696, 620-664, and 317-602 for the 0, 10, and 40 ppm DDE groups | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | decreased | eggshell thickness versus controls | Female | Adult | 20-28, 21-25, and 10-23 for the 0, 10, and 40 ppm DDE groups | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | no effect | Ca - ATPase activity in eggshell glands versus controls | Female | Adult | 5 hens; 19 eggs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | no effect | plasma glucose, NEFA, urea, or uric acid versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | liver cadmium concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | DDT <0.1, DDE 0.2 - 1.2 ug/g dry wt @ 0 ppm; DDT 0.6 - 2.4, DDE 1.2 - 10.1 @ 2 ppm; DDT 2.2 - 29.2, DDE 15.7 - 153.5 @ 20 ppm; DDT 14.9 - 102.0, DDE 45.0 - 187.0 @ 200 ppm | DDT and DDE concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean hematocrit values compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 706 - 1,995 | steady state bioconcentration factor for lipid, calculated on a wet weight basis; range for 7 doses | Not Reported | Juvenile | 8-16/dose | Toxicity Factor Datasets | 1 d at initiation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | egg production during study period | Female | Adult | 5-10/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | 6% decrease @ 10 ppm | eggshell thickness | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
TRICHLOROPHENOXYACETIC ACID (2,4,5-) | 106 lbs AI/acre (slope = 3.7) for exposure of 3d embryo; 116 lbs AI/acre (slope = 3.8) for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | Toxicity Factor Datasets | 3 or 8d of development | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FENTHION | 100% @ 5 mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | decreased @ all doses | food consumption compared with controls | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLPARATHION | decreased if treatment initiated during egg laying | proportion of hens laying and number of eggs laid per hen compared to controls | Female | Adult | 12 pairs /group | Toxicity Factor Datasets | 7 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIAZINON | decreased @ 15 (aqueous), 2.0 (oil) lb/acre | embryo weight by day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory |
Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|
see citation tables | incidence of reduced growth and abnormal survivors for 42 compounds | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | incubation day 3-8 | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIISOPROPYL METHYLPHOSPHONATE | decrease | mean blood pressure, compared to baseline prior to exposure | Both Male and Female | Adult | 12 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
VANADYL SULFATE | no effect | body weight and food consumption compared among groups | Both Male and Female | Adult | 5 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase @ 5% | incidence of degeneration of kidney tubules | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | no effect | body weight versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CYANIDE | increased @ 1, 2 mg/kg bw | serum creatine kinase activity versus controls | Female | Adult | at least 5 determinations/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE | decreased @ 5,000 ppm, incub. day 3 exposure | embryo survival through day 18 of incubation and % of survivors that were normal versus controls | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | 3 or 8 days of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decreased @ 500, 1000, 5000 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE, LEAD CHLORIDE | 4.1 (0.5) @ 10 ppm Pb; 22.5 (1.5) @ 100 ppm Pb; 3.1 (0.3) @ 5 ppm Cd + 5 ppm Pb; 16.1 (1.4) @ 50 ppm Cd+ 50 ppm Pb (ug/g, dry wt) | mean (SE) Pb concentrations in kidney | Male | Juvenile | 6-8 birds/dose | Toxicity Factor Datasets | 128 d (at initiation) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM | decreased @ 300 ppm | growth rate versus controls | Male | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | increased @ 200, 800 ppm | food consumption compared to controls | Both Male and Female | Adult | 6 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | 4.627 (@ 2 ppm), 54.333 (@ 20 ppm), 77.222 (@ 200 ppm) ppm, wet wt | mean Cd concentrations in kidneys after 90 d of treatment | Both Male and Female | Adult | 20 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | increased @ 3 ppm | incidence of brain lesions (demyelination, necrosis, neuronal shrinkage) | Not Reported | Juvenile | 3-11 ducklings/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | no effect | survival rate compared to controls | Not Reported | Juvenile | 25 birds/group | Toxicity Factor Datasets | 1 day | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM, SELENOMETHIONINE | increased @ 25 ppm | plasma uric acid concentration in hatchlings versus controls | Not Reported | Juvenile | 5-11 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | no effect | reproductive success or nest attentiveness versus controls | Both Male and Female | Adult | 22 pairs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | no effect | histological changes to nervous system, bones, feathers, feather follicles, claws and scaled skin versus controls | Male | Adult | 21/dose | Toxicity Factor Datasets | 14 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | California Counties |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | higher in P8 than in T19 and TF, and in T19 than in TF | maximum likelihood estimate of 2-week Pb exposure rate | Both Male and Female | Both Adults and Juveniles | 50 birds/treatment | Sacramento National Wildlife Refuge; Willows, CA (39deg29'N, 122deg20'W) | Toxicity Factor Datasets | Sacramento |
Peregrine Falcon (Falco peregrinus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
AROCLOR 1248, AROCLOR 1254, AROCLOR 1260, DDE (4,4'-), DDT (4,4'-), MERCURY COMPOUNDS | no effect | eggshell thickness compared to pre-1947 reference eggs | Female | Adult | 9 eggs | urban nest sites | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 1.89 (1.27-2.43) -6.96 (3.28-13.37) ppm, wet wt | annual mean (range) concentrations in eggs | Female | Adult | 3-6 eggs/year | Amchitka Island | Toxicity Factor Datasets |
DDE (4,4'-) | 7.5% decrease | eggshell thickness compared to "pre-pesticide" reference eggs | Female | Adult | 3-6 eggs/year | Amchitka Island | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
MERCURY (elemental) | 6.90-29.50 ppm, dry wt (females) 12.10 ppm, dry wt (males) |
concentrations measured in primary and rectrix feathers | Both Male and Female | Adult | 20 females, 1 male | Northern Sweden | Toxicity Factor Datasets | SWEDEN |
MERCURY (elemental) | 2.79 (3.10) ppm, dry wt | mean (SD) concentration measured in feathers | Not Reported | Juvenile | 3 nests | Southern Sweden | Toxicity Factor Datasets | SWEDEN |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | review | concentrations of chemicals in eggs and diet associated with mortality and eggshell thinning (various raptor species) | Not Reported | Adult | Not Reported | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 13.1% and 13.6% decreases in tundrius and anatum ssp. | eggshell thickness compared to pre-1947 reference eggs | Female | Adult | 21 and 34 eggs for tundrius and anatum ssp. | Toxicity Factor Datasets |
American Kestrel (Falco sparverius)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 48% decrease at 625 mg/kg bw 27% decrease at 125 mg/kg bw 12% decrease at 25 mg/kg bw |
red blood cell hemoglobin content | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | decrease at all doses (45-59%) | red blood cell delta aminolevulinic acid dehydratase | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | 7.84 ppm femur at 120 ppm; 16.60 ppm femur at 212 ppm; 18.44 ppm femur at 448 ppm | mean lead concentration in femur | Both Male and Female | Adult | 8-14/group | Toxicity Factor Datasets | 1-2 yr | Laboratory | |
LEAD COMPOUNDS | no effect | packed cell volume, hemoglogin concentration, erythrocyte counts | Both Male and Female | Adult | 8-14/group | Toxicity Factor Datasets | 1-2 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLPARATHION | decrease at 1, 2, 3 mg/kg bw | brain acetylcholinesterase activity 10 hr post-dose | Both Male and Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
METHYLPARATHION | increased at 2, 3 mg/kg bw | plasma glucose concentrations | Both Male and Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 1.37 (0.10 SE) mg/kg | mean DDE concentration in blood (wet wt) | Not Reported | Adult | 6 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|
FENTHION | 100% | Male | Adult | 14 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FLUORIDE, SODIUM | increased at 1120, 2240 ppm | % bone ash | Both Male and Female | Juvenile | 9-10/group | Toxicity Factor Datasets | 7 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1262, POLYCHLORINATED DIBENZO-P-DIOXINS | increased @ 0.5, 5 ppm | in vitro microsomal breakdown of oestradiol | Both Male and Female | Adult | 4/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PARAQUAT | 86% of control @ 25 mg/kg, 74% of control @ 60 mg/kg | body weight by 10 days of dosing | Not Reported | Juvenile | 11/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DICOFOL | decreased 5.45% (@ 5 mg/kg), 10.98% (@ 20 mg/kg) | eggshell thickness compared to controls | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | increased @ 2.3, 23, 233 ng/g | incidence of malformations or edema, and EROD activity versus controls | Not Reported | Hatchling | 24-26/treatment group | Toxicity Factor Datasets | hatchling | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | reduced @ 12 ppm Se | ratio of # fertile eggs to total # eggs laid versus 6 ppm Se group | Both Male and Female | Adult | 15 pairs/treatment group; 10 control pairs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decrease at 10 ppm | mean eggshell thickness | Female | Adult | 8-10 | Toxicity Factor Datasets | Laboratory |
Mourning Dove (Zenaida macroura)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
AZINPHOS-METHYL (GUTHION), DIMETHOATE, ENDOSULFAN, METHYLPARATHION, PARATHION, PERMETHRIN, THIRAM, ZIRAM | decreased in conventional orchards | hatching success | Not Reported | Nestling | 29 conventional nests | York Springs, Adams Co. | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased | blood delta-aminolevulinic acid dehydratase activity | Not Reported | Not Reported | 5 birds | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Condition | Lab |
---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | increased at 10, 40 ppm | length of courtship period | Both Male and Female | Adult | 8/group | Toxicity Factor Datasets | breeding | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
ALDRIN, DIELDRIN | <0.1 ppm aldrin, 3.8 ppm dieldrin, 0.3 ppm DDT and metabolites, wet wt | post-mortem whole body concentrations | Not Reported | Not Reported | 1 bird | Toxicity Factor Datasets |
Burrowing Owl (Athene cunicularia formerly Speotyto cunicularia), Great Horned Owl (Bubo virginianus)
Chemical | Endpoint Value | Location | Type |
---|---|---|---|
CARBARYL, CARBOFURAN, DDE (4,4'-) | review | Toxicity Factor Datasets |
Great Horned Owl (Bubo virginianus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CHLOROPHACINONE | 99 ug | total carcass residues 28 d after removal from treatment | Not Reported | Adult | 1 owl | Toxicity Factor Datasets | Laboratory |
Loggerhead Shrike (Lanius ludovicianus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | decreased | eggshell thickness index compared with reference samples collected in 1875-95 | Not Reported | Embryo | 20 clutches, 104 eggs | southern IL | Toxicity Factor Datasets |
Double-crested Cormorant (Phalacrocorax auritus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | increased at 10, 100 ug/kg | hepatic microsomal cytP450 content | Not Reported | Hatchling | 6-10 eggs/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | no effect | weight of brain, heart, liver and spleen versus controls | Not Reported | Hatchling | Not Reported | Toxicity Factor Datasets | Laboratory |
Mallard duck (Anas platyrhynchos), Double-crested Cormorant (Phalacrocorax auritus)
Chemical | Endpoint Value | Endpoint Description | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|
POLYCHLORINATED BIPHENYLS | review | incidence of reproductive effects | Both Adults and Juveniles, Embryo | Not Reported | Toxicity Factor Datasets |