Mallard duck (Anas platyrhynchos)
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease | plasma prolactin levels during oviposition, early incubation and post-natal care | Female | Adult | 5-12/dose | Toxicity Factor Datasets | 10 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | behavior of offspring; latency in response to approach a maternal call and distance travelled from a frightening stimulus | Female | Adult | 4 adults/dose; 141-175 offspring/dose | Toxicity Factor Datasets | 10 mo | Laboratory | |
DDE (4,4'-) | 0.021 - 0.028 ppm wet wt @ 0 ppm; 5.8 (0.32 SE; range 4.28-7.23) ppm wet wt @ 3 ppm | mean and range of DDE egg concentrations | Female | Adult | 8 eggs/dose | Toxicity Factor Datasets | 10 mo | Laboratory | |
DDE (4,4'-) | increase @ 3 ppm | responsiveness of offspring to maternal call; % that approached call and % that spent 100% of time near call after initial approach | Female | Adult | 4 adults/dose; 148-156 offspring/dose | Toxicity Factor Datasets | 10 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 200.7 (coeff. of variation 22.3%) | 5 day dietary LC50 | Not Reported | Juvenile | 8-10/dose | Toxicity Factor Datasets | 5 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PARATHION | 9% @ 1 mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 6/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory | |
FENTHION | 67% @ 2.2 mg/L | percent mortality | Not Reported | Juvenile | 6/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | decreased @ all doses | body weight gain by 8 days compared with controls | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 7 d | Laboratory | |
DDT (4,4'-) | 1550 ppm | 5 day dietary LC50 | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 7 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIAZINON | 74 (day 3), 79 (day 8) lb/acre LC50 | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
PARATHION | decreased @ 7.5 lb/acre (aqueous); 0.08, 0.8 lb/acre (oil) | crown-rump length at day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PARATHION | 4/36 | mortality incidence by 20 hrs post-dose | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
MALATHION | 7/36 | mortality incidence by 20 hrs post-dose | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEPTOPHOS | decreased @ all doses | activity of brain and plasma cholinesterase, and brain neurotoxic esterase compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
LEPTOPHOS | decreased @ 60, 270 ppm | plasma alkaline phosphatase activity compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254, DDE (4,4'-) | no effect | food consumption rate (181 g/d) compared to control (173 g/d) | Female | Adult | 10/dose | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1254 | no effect | eggshell thickness | Female | Adult | 10 hens/dose; 8-9 eggs/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | egg weight, length or breadth, compared to control | Female | Adult | 21-25/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | California Counties | Lab |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased @ 2 #four shot | spleen plaque forming cell counts, % packed cell volume versus controls | Both Male and Female | Adult | 16 (2 #four shot) 63 (field exposure) |
Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EPN | decreased @ 36 (cholineserase only), 108 ug/g | plasma alkaline phosphatase, aspartate aminotransferase, cholinesterase activities, and uric acid | Not Reported | Embryo | 12/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory | |
EPN | decreased @ 12, 36, 108 ug/g | embryo weight and length, % normal survivors versus controls | Not Reported | Embryo | 12/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory | |
EPN | decreased @ 12, 36 ug/g | brain weight, protein content, acetylcholinesterase and neurotoxic esterase versus controls | Not Reported | Hatchling | 12/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | lead only: 3.53 (+/- 1.43); lead-iron: 1.42 (+/- 0.65) ppm, wet wt | lead concentration in kidneys (mean +/- SE) | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
LEAD (elemental) | lead only: 1.02 (+/- 0.22); lead-iron: 0.75 (+/- 0.10) ppm, wet wt | lead concentration in kidneys (mean +/- SE) | Male | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD NITRATE | decreased @ 25 ppm/3 wks, 5 ppm/12 wks | delta-aminolevulinic acid dehydratase activity in blood versus controls | Male | Adult | 20/dose; 5/dose x time group | Toxicity Factor Datasets | 1 yr | Laboratory | |
LEAD NITRATE | increased @ 25 ppm/3wks | accumulation in livers and kidneys versus controls | Male | Adult | 20/dose; 5/dose x time group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 78.2 (carcass); 61.6 (egg); 4.1 (brain) ppm, wet wt | DDE residues in whole carcass, egg contents, and brain | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
MERCURY COMPOUNDS | 2.5 (carcass); 1.25 (egg); 23.7 (kidney) ppm, wet wt | mercury residues in whole carcass, egg contents, and kidneys | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | 0.03 (@ 0 ppm), 0.02 (@ 2 ppm), 0.72 (@ 20 ppm) 8.47 (@ 200 ppm) ppm, wet wt | mean Cd concentrations in testes (ppm, wet wt) by 90 days | Male | Adult | 5 birds | Toxicity Factor Datasets | first year | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ALUMINUM SULFATE | increased to 61% @ 1000 (LL), 100% @ 5000 (LL) | mortality versus controls | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | 1 d | Laboratory | |
ALUMINUM SULFATE | decreased @ 1000 (LL) | food consumption versus controls | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | no effect | bill length | Both Male and Female | Juvenile | 36 birds/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
NICKEL SULFATE | decreased @ 1200 pmm (30 d of age) | weight:length of humerus | Male | Juvenile | 36 birds/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SALINE WATER | decreased @ 20,000 and 21,500 umhos/cm | body weight by day 14 versus controls | Not Reported | Juvenile | 10 birds/group | Toxicity Factor Datasets | 2 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | 9.10 (whole body), 4.46 (carcass), 16.5 (liver), 17.6 (kidney) ppm, wet wt | mean Hg concentrations after 2 wk exposure | Male | Adult | 3-5 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased to 4.8 (@ 10 ppm), 26.0 (@ 20 ppm), 68.0 (@ 40 ppm) ppm, wet wt | Se concentrations in livers after 6 wks of treatment | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
SELENITE, SODIUM | increased to 0.4 (@ 0 ppm), 5.0 (@ 10 ppm), 3.2 (@ 20 ppm), 2.8 (@ 40 ppm) ppm, wet wt | Se concentrations in livers after 6 wks of treatment versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | increased @ 20 ppm | incidence of kidney lesions by 12 wks of treatment compared to controls | Not Reported | Juvenile | 12 birds per timexdose treatment | day old | Toxicity Factor Datasets | Laboratory |
CADMIUM CHLORIDE | increased @ 20 ppm | serum glutamic pyruvic transaminase activity by 8 wks of treatment compared to controls | Not Reported | Juvenile | 12 birds per timexdose treatment | day old | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | increased @ 15 ppm Se (with and w/out B), 1000 ppm B | incidence of plasma chemistry changes versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
BORIC ACID, SELENOMETHIONINE | decreased @ 1000 ppm B | hematocrits and hemoglobin concentrations versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM | increased @ 100 ppm ( 0.4 ppm, dry wt), 300 ppm (0.8 ppm, dry wt) | accumulation of arsenic in brain tissue (geometric means in parentheses) | Both Male and Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decreased @ 1, 5 uL/egg | bill length of both sexes | Both Male and Female | Hatchling | 65 eggs/group | Toxicity Factor Datasets | 3 days | Laboratory | |
CRUDE OILS | decreased @ 5 uL/egg | embryonic weight (females) and crown rump length (both sexes) | Both Male and Female | Hatchling | 65 eggs/group | Toxicity Factor Datasets | 3 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | nasal gland and kidney Na-K-ATPase activity, following exposure to 100% seawater | Both Male and Female | Juvenile | 4-5 | Toxicity Factor Datasets | 3-5 mo | Laboratory | |
DDE (4,4'-) | no effect | body weight or plasma electrolyte levels | Both Male and Female | Juvenile | 4 | Toxicity Factor Datasets | 3-5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase @ 1 and 3% | daily food intake rate | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 18 wks | Laboratory | |
CRUDE OILS | decrease @ 0.5, 1, 3% | plasma corticosterone concentration, compared to control | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 18 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
BORIC ACID | Egg; 3 ug/g @ 30 ppm, 13 ug/g @ 300 ppm, 49 ug/g @ 1000 ppm: Liver; 15 ug/g @ 300 ppm, 33 ug/g @ 1000 ppm: Brain; 14 ug/g @ 300 ppm, 41 ug/g @ 1000 ppm | boron concentrations in adult tissues (geometric mean; ug/g dry weight). | Both Male and Female | Adult | 10-20/dose | Toxicity Factor Datasets | Laboratory | |
BORIC ACID | Liver; 3 ug/g @ 30 ppm, 17 ug/g @ 300 ppm, 51 ug/g @ 1000 ppm: Brain; 4 ug/g @ 30 ppm, 19 ug/g @ 300 ppm, 66 ug/g @ 1000 ppm | boron concentrations in ducklings 21 d of age (geometric mean; ug/g dry weight). Concentrations at other doses were not detected. | Both Male and Female | Juvenile | 10-13/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FUEL OILS | decrease @ 5, 10, 20, 50 ul | 6-day % survival of mallard embryos from eggs treated on the 8th day of incubation | Not Reported | Embryo | 50/dose | Toxicity Factor Datasets | 8d of incubation | Laboratory | |
FUEL OILS | decrease @ 5, 10, 20, 50 ul | 30-d % hatching success | Not Reported | Embryo | 50/dose | Toxicity Factor Datasets | 8d of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
TRIMETHYLTIN CHLORIDE | 17% decrease @ 5 ppm | body weight | Not Reported | 5/dose | Toxicity Factor Datasets | 3-4 d | Laboratory | ||
TRIMETHYLTIN CHLORIDE | increase @ 5 ppm | cephalic tumor incidence | Not Reported | Juvenile | 5/dose | Toxicity Factor Datasets | 3-4 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PHOSPHORUS (YELLOW OR WHITE) | decreased @ 235.0, 484.2, 972.0 ug/g (nominal concentrations) | body weight versus controls | Both Male and Female | Adult | 5 males, 5 females/dose | Toxicity Factor Datasets | Laboratory | |
PHOSPHORUS (YELLOW OR WHITE) | 91.1 ug/g | No Observable Effect Level, based on mortality, pathology, clinical signs | Both Male and Female | Adult | 5 males, 5 females/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM | figure/table | figures and tables of selenium concentration over time (% of administered dose) | Female | Adult | Not Reported | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased @ 40 ppm | incidence of macroscopic abnormalities of muscles, claws and feathers versus controls | Male | Adult | 21/dose | Toxicity Factor Datasets | 1 yr | Laboratory | |
SELENOMETHIONINE | decreased in birds that died | mean weights of heart, spleen, pancreas, testis versus controls | Male | Adult | 21/dose | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | reduced @ 7 ppm Se | body weight and weight gain at 7 and 14 days post-hatch versus 3.5 ppm Se group | Both Male and Female | Juvenile | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory | |
BORIC ACID, SELENOMETHIONINE | increased @ 3.5 ppm Se | survival between 7 and 14 days post-hatch versus controls | Both Male and Female | Juvenile | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | increased @ 642 and 1284 ug/g | occurrence of renal tubular nuclear inclusion bodies versus controls | Male | Adult | 10/ Pb treatment; 5/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | 3.0(0.30) ppm @ 642 ug/g Pb; 6.8(0.84) ppm @ 1284 ug/g Pb | mean (SE) wet wt Pb concentrations in blood | Male | Adult | 10/ Pb treatment; 5/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | reduced for lead shot | hematocrit and hemoglobin concentrations versus all other groups | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory | |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | increased for lead shot | plasma activities of alanine aminotransferase, creatine phosphokinase, aspartate aminotransferase, lactate dehydrogenase versus control group | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 16(0.8) ppm, egg, 22(1.5) ppm, fem. liver, 71(8.9) ppm, male liver @ 10 ppm Hg; 17(0.6) ppm, egg, 21(4.3) ppm, female liver, 65(4.1) ppm, male liver @ 10 ppm Se + 10 ppm Hg | mean(SE) wet wt concentration of Hg in egg and liver of treated birds | Both Male and Female | Adult | 12/group | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | increased with Pb, no effect with Fe or Bi | mortality versus controls | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | decreased with Pb; no effect with Fe or Bi | body weight, gonad weight, hematocrit versus controls | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CYANOFENPHOS | increased | incidence of delayed neurotoxicity signs | Both Male and Female | Juvenile | 10 | laboratory | Toxicity Factor Datasets | 1 week | Laboratory |
CYANOFENPHOS | increased (30% @ 10 mg leptophos/kg/d; 10% @ 0.5 mg cyanofenphos/kg/d; 0% @ 1.0 mg cyanofenphos/kg/d; 20% @ 2.0 mg cyanofenphos/kg/d ;60% @ 4.0 mg cyanofenphos/kg/d; 100% @ 8.0 mg cyanofenphos/kg/d | mortality versus controls) | Both Male and Female | Juvenile | 10 | laboratory | Toxicity Factor Datasets | 1 week | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | liver: 18.7 d muscle: 30.1 d |
half life of selenium in tissues | Both Male and Female | Adult | 3 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ENDOSULFAN | 6.47 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 7 days | Laboratory | |
ENDOSULFAN | 7.89 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 30 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | increased@ 4, 10, 30 ppm | hepatic microsomal enzyme activity versus controls | Both Male and Female | Juvenile | 5-15 per group | Toxicity Factor Datasets | 75 days | Laboratory | |
DIELDRIN | increased @ 30 ppm | liver protein concentration versus controls | Both Male and Female | Juvenile | 5-15 per group | Toxicity Factor Datasets | 75 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | kidney Cu concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | kidney Zn concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD ACETATE | increased | iron concentration in liver versus controls | Male | Adult | 10 (controls); 30 (treated) | Toxicity Factor Datasets | Laboratory | |
LEAD ACETATE | increased | liver and kidney Pb concentrations versus controls | Male | Adult | 30 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | no effect | fertility, hatchability and duckling weight | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory | |
DIELDRIN | no effect | fertility, hatchability and duckling weight | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 5.7 ppm (whole blood); 6.2 ppm (liver); 2.4 ppm (spleen) @ 300 mg/kg body weight | lead concentrations in tissues, 96 hr after exposure to lead in ducklings receiving vitamin E | Not Reported | Juvenile | 5/dose | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1242 | no effect @ 150 ppm | embryo mortality, # infertile eggs/clutch or # eggs hatched/clutch | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1242 | 8.9% decrease @ 150 ppm | eggshell thickness, compared to control | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DICOFOL | no effect | egg production during study period | Female | Adult | 4-8/dose | Toxicity Factor Datasets | Laboratory | |
DICOFOL | no effect | body weight at end of study | Female | Adult | 4-8/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LINDANE | decrease @ 20 mg/kg 7x and 3x/wk | egg production and vitellogenin concentration in plasma, liver and ovary | Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
LINDANE | no effect | body weight at end of study | Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | decreased | body weight compared to controls | Both Male and Female | Adult | 24 pairs/dose | Toxicity Factor Datasets | 7 and 11 months old | Laboratory | |
CHLORPYRIFOS | decreased | brain acetylcholinesterase activity compared to controls | Both Male and Female | Adult | 24 pairs/dose | Toxicity Factor Datasets | 7 and 11 months old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease @ 5% | growth rate, estimated as change in body weight, compared to control | Both Male and Female | Juvenile | 50/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
IRON (elemental), LEAD (elemental) | increased @ 8 #four iron shot | serum glutamic pyruvic transaminase activity vs controls | Female | Adult | 8/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM, SELENOMETHIONINE | increased (40%) @ 60 ppm Se | incidence of mortality versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | increased @ 0.5, 3 ppm | changes in approach behavior (maternal call stimulus) | Not Reported | Juvenile | 249 (control); 276 (0.5 ppm); 108 (3 ppm) | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | 13-20 ppm, wet wt | mean Se concentration in eggs | Female | Adult | 5 birds | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | no effect | % survival versus controls | Not Reported | Juvenile | 15/group | Toxicity Factor Datasets | 1-day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EMAMECTIN BENZOATE | no effect | numbers of eggs laid and hatched, eggshell thickness, and 14-day hatchling survival versus controls | Both Male and Female | Both Adults and Juveniles | 16 pairs/group | Toxicity Factor Datasets | 22 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | reduced @ 10 ppm Se, 10 ppm Se + 10 ppm Hg | hematocrit and hemoglobin values versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | increase @ 15, 30 ppm | plasma and liver GSH-peroxidase activity (for all Se forms), compared to controls | Not Reported | Juvenile | 10/dose | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DICROTOPHOS | 63% | maximal brain acetylcholinesterase activity inhibition compared to control (4 hrs post-dose) | Not Reported | Juvenile | 4/group | Toxicity Factor Datasets | 1 day old | Laboratory |