Laboratory
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 36-67% decrease @ 10-1000 ppm | salt gland excretion volume, compared to controls | Male | Not Reported | 12/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DICROTOPHOS | decreased @ 55 and 145 ppm | consumption of treated diet compared with controls | Not Reported | Juvenile | 8-10/dose | Toxicity Factor Datasets | 5 days | Laboratory | |
DICROTOPHOS | 506.7 (coeff. of variation = 40.3%) | 5 day dietary LC50 | Not Reported | Juvenile | 8-10/dose | Toxicity Factor Datasets | 10 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ACEPHATE | 109.7% @ 5mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory | |
PARATHION | 100% @ 1 mg/L | percent mortality | Not Reported | Juvenile | 6/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ASULAM | decreased @ all doses | body weight gain by day 8 compared with controls | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 7 d | Laboratory | |
DDT (4,4'-) | decreased @ all doses | food consumption compared with controls | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 7 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
MALATHION | decreased @ 125 lb/acre | crown-rump length at day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 8 of incubation | Laboratory | |
DIAZINON | decreased @ 2.0 lb/acre | crown-rump length at day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 8 of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ACEPHATE | 11/36 | mortality incidence by 20 hrs post-dose | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease | % fertile eggs and # of ducklings; when male, female or both male and female exposed to oil, compared to control | Female | Adult | 3 pairs/dose | Toxicity Factor Datasets | 5.5 mo at initiation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 17% decrease | eggshell thickness, compared to control | Female | Adult | 10 hens /dose; 8 eggs/dose | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1254, DDE (4,4'-) | 19% decrease | eggshell thickness, compared to control | Female | Adult | 10 hens/dose; 8 eggs/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | egg weight, length or breadth, compared to control | Female | Adult | 21-25/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased @ 1 #four shot | mortality rate by 15 d post-dose versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | decreased @ 1 #four shot, 7, 14, 21 d. post-dose | agglutination titers to sheep red blood cells versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CYANIDE | decreased @ 0.5,1,2 mg/kg bw | respiratory control ratios in heart, liver and brain versus controls | Female | Adult | at least 5 determinations/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FUEL OILS | decreased @ 0.5, 5 ul/egg on incubation day 3 or 8 | embryo survival to day 18 of incubation and % of survivors that were normal versus controls | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | 3 or 8 days of incubation (time of treatment) | Laboratory | |
FUEL OILS | decreased @ 0.5 ul/egg, incubation day 3 or 8 exposure | embyronic length and weight by incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | 3 or 8 days of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | decreased @ 1000 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | Toxicity Factor Datasets | Laboratory | |
CHLOROETHYLMERCURY | decreased @ 500 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | decreased @ 200 ppm | weight of testes versus controls | Male | Adult | 5 birds | Toxicity Factor Datasets | first year | Laboratory | |
CADMIUM CHLORIDE | increased @ 200 ppm | incidence of kidney lesions versus controls | Both Male and Female | Adult | 10 birds | Toxicity Factor Datasets | first year | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM | increased @ 10, 100, 300 ppm | incidence of altered brain and liver biochemistry | Both Male and Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory | |
ARSENATE, SODIUM | increased @ 100 ppm ( 0.3 ppm, dry wt), 300 ppm (1.3 ppm, dry wt) | arsenic concentrations in liver (geometric means in parentheses) | Both Male and Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | increased @ 12.5, 50, 200, 800 ppm diet | kidney, blood, liver, and feather concentrations of Ni compared to controls | Both Male and Female | Adult | 6 pairs/group | Toxicity Factor Datasets | Laboratory | |
NICKEL SULFATE | 1.94 (kidney), 0.52 (liver), 0.139 (blood), 68.06 (feathers) ppm, wet wt | mean tissue concentrations @ 800 ppm Ni in diet | Both Male and Female | Adult | 6 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SALINE WATER | decreased @ 4000 or 7720 umhos/cm | body weight by day 14 or 16 versus controls | Not Reported | Juvenile | 10 birds/group | Toxicity Factor Datasets | 2 d | Laboratory | |
SALINE WATER | increased | plasma protein levels; serum osmolality; salt, kidney and adrenal gland size versus controls | Not Reported | Juvenile | 10 birds/group | Toxicity Factor Datasets | 2 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE | decreased @ 27, 90 ug Hg | embryo crown to rump length by day 18 of incubation versus controls | Both Male and Female | Embryo | 80 eggs/group | Toxicity Factor Datasets | incubation day 3 | Laboratory | |
METHYLMERCURY CHLORIDE | decreased @ 9, 27, 90 ug Hg | % survival by day 18 of incubation versus controls | Both Male and Female | Embryo | 80 eggs/group | Toxicity Factor Datasets | incubation day 3 | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased @ 20, 40 ppm | hepatic malondialdehyde concentrations versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
SELENITE, SODIUM | increased @ 40 ppm | hepatic malondialdehyde concentrations versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | increased @ 450 ppm | plasma uric acid, adrenal corticosterone levels | Not Reported | Adult | 12 birds/group | Toxicity Factor Datasets | 1 yr | Laboratory | |
CADMIUM CHLORIDE | no effect | food consumption compared to controls | Not Reported | Adult | 12 birds/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | decreased @ 60 ppm Se | body, liver, and spleen weight; tarsus length versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
BORIC ACID, SELENOMETHIONINE | decreased @ 60 ppm Se (100% mort.) | survival versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
TOXAPHENE (POLYCHLORINATED CAMPHENES) | 130 (80.4-210), 30.8 (23.3-40.6), 70.7 (37.6-133) | LD50's determined at ages 36 hr, 7 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hr, 7 d, 30 d, or 6 mos | Laboratory | |
ENDOSULFAN | 6.47 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 7 days | Laboratory | |
MEXACARBATE | 3.16 (2.17-4.61), 4.11 (2.70-6.26), 3.61 (2.37-5.49), 3.23 (2.72-3.85), 2.72(2.28-3.23) | LD50's determined at ages 48 hr, 7 d, 14 d, 30 d and 60 d, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hr, 7 d, 30 d, or 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM | 18(4.8) ppm, wet wt @ 40 ppm; 6.9(2.07) ppm, wet wt @ 80 ppm | mean liver concentrations (SE) in ducklings fed selenite that died | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | Laboratory | |
SELENOMETHIONINE | 60(14.2) ppm, wet wt @ 40 ppm; 51(5.2) ppm, wet wt @ 80 ppm | mean liver concentrations (SE) in ducklings fed selenomethionine that died | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 10.6 +/- 2.2 ppm nasal gland, 16.1 +/- 5.1 ppm liver, 5.8 +/- 1.1 ppm kidney, 1.9 +/- 0.1 ppm brain @ 100 ppm diet | mean (+/- SE) DDE levels (ppm wet weight) | Both Male and Female | Juvenile | 4 | Toxicity Factor Datasets | 3-5 mo | Laboratory | |
DDE (4,4'-) | no effect | nasal gland secretion volume | Both Male and Female | Juvenile | 5-11 | Toxicity Factor Datasets | 3-5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase @ 3% | body weight | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 18 wks | Laboratory | |
CRUDE OILS | increase @ 1 and 3% | daily food intake rate | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 18 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
BORIC ACID | decrease @ 30, 300, 1000 ppm | hatchling weight gain over 21 d, compared to controls | Both Male and Female | Hatchling | 11-23/dose | Toxicity Factor Datasets | Laboratory | |
BORIC ACID | Egg; 3 ug/g @ 30 ppm, 13 ug/g @ 300 ppm, 49 ug/g @ 1000 ppm: Liver; 15 ug/g @ 300 ppm, 33 ug/g @ 1000 ppm: Brain; 14 ug/g @ 300 ppm, 41 ug/g @ 1000 ppm | boron concentrations in adult tissues (geometric mean; ug/g dry weight). | Both Male and Female | Adult | 10-20/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
COREXIT 9527 | increase | plasma alanine aminotransferase activity, compared to control | Not Reported | Juvenile | 25/dose | Toxicity Factor Datasets | 4 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
TRIMETHYLTIN CHLORIDE | increase @ 50 ppm | incidence of mild to marked degeneration of neurons of the pons, medulla oblongata, gray matter of the spinal cord and pyrimidal cells of the cerebral cortex; mild to moderate lympoid depletion of spleen and thymus; atrophy of myofibers in skeletal and ca | Not Reported | Juvenile | 5/dose | Toxicity Factor Datasets | 3-4 d | Laboratory | |
TRIETHYLTIN CHLORIDE | decrease @ 50 ppm | body weight, compared to control | Not Reported | Juvenile | 5/dose | Toxicity Factor Datasets | 3-4 d | Laboratory | |
TRIMETHYLTIN CHLORIDE | 17% decrease @ 5 ppm | body weight | Not Reported | 5/dose | Toxicity Factor Datasets | 3-4 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | increased @ 100, 250, 500 mg/kg bw | thyroid wt/body wt and liver wt/body wt ratios versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EMAMECTIN BENZOATE | 76 mg/kg bw, 56-102 (95% CI) | acute oral LD50 | Both Male and Female | Adult | 10/dose | Toxicity Factor Datasets | 19 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | decreased @ 900 ppm B | liver weight versus 450 ppm B group | Male | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | reduced @ 828 ug/g | hemoglobin concentrations versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | reduced @ 869 and 954 ug/g | delta aminolevulinic acid dehydratase activity versus corn or complete diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | no effect | body weight versus controls | Both Male and Female | Adult | 12/group | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 3.4(0.22) ppm @ 10 ppm Se; 5.2(0.44) ppm @ 10 ppm Hg + 10 ppm Se | mean (SE) wet wt Se concentrations in brain | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no effect with Fe or Bi | egg weight, eggshell thickness, fertility, hatchability versus controls | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CYANOFENPHOS | increased | incidence of delayed neurotoxicity signs | Both Male and Female | Juvenile | 10 | laboratory | Toxicity Factor Datasets | 1 week | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | liver: 18.7 d muscle: 30.1 d |
half life of selenium in tissues | Both Male and Female | Adult | 3 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | increased@ 4, 10, 30 ppm | hepatic microsomal enzyme activity versus controls | Both Male and Female | Juvenile | 5-15 per group | Toxicity Factor Datasets | 75 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | kidney Cu concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD ACETATE | increased | iron concentration in liver versus controls | Male | Adult | 10 (controls); 30 (treated) | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | no effect | incidence of illness versus controls | Both Male and Female | Adult | 15 pairs/treatment group, 10 pairs/control group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1242 | no effect @ 150 ppm | embryo mortality, # infertile eggs/clutch or # eggs hatched/clutch | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 16.4 ug/g diet | 24-d LOAEL based on growth impairment | Not Reported | Juvenile | 10/dose | Toxicity Factor Datasets | 1 - 25 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase | length of reproductive cycle; due to prolonged phase of gonadal maturation | Female | Adult | 17 pairs/dose | Toxicity Factor Datasets | 10 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ENDRIN | see citation | figures of carcass and blood endrin concentrations during elimination period (0-64d) | Male | Adult | 2-5/sample | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEPTOPHOS | decreased @ 260 ppm | body weight growth compared with controls | Both Male and Female | Juvenile | 3-5/group | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase | metabolic heat production (watts/kg), compared to pre-contamination levels | Not Reported | Adult | 3/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease @ 5% | growth rate, estimated as change in body weight, compared to control | Both Male and Female | Juvenile | 50/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased | body weight and delta-aminolevulinic acid dehydratase activity versus controls | Male | Adult | 20/treatment group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | no effect | body weight and food consumption versus controls | Both Male and Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FUEL OILS | decrease @ 5, 10, 20, 50 ul | 6-day % survival of mallard embryos from eggs treated on the 8th day of incubation | Not Reported | Embryo | 50/dose | Toxicity Factor Datasets | 8d of incubation | Laboratory |
Western Toad (Anaxyrus boreas formerly Bufo boreas)
Chemical | Endpoint Value | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|
IRON SULFATE | increase @ 30-288 mg/l | Not Reported | Juvenile | 5-25/dose | Toxicity Factor Datasets | larvae | Laboratory |
Coyote (Canis latrans)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PENTACHLOROBENZENE | no effect | mean body mass and appearance of eyes, gums, teeth and fur, compared to controls | Both Male and Female | Adult | 3/dose | Toxicity Factor Datasets | 2 - 12 yrs | Laboratory | |
PENTACHLOROBENZENE | no effect | serum chemistry and hematological profile, compared to control | Both Male and Female | Adult | 3/dose | Toxicity Factor Datasets | 2 - 12 yrs | Laboratory |
Pacific Treefrog (Pseudacris regilla formerly Hyla regilla)
Chemical | Endpoint Value | Endpoint Description | Units | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|---|
AMMONIUM SULFATE | 6.1 | NOAEL for body weight | mg NH4-N/L | Not Reported | Embryo | 10/replicate; 3 replicates/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
AZINPHOS-METHYL (GUTHION) | 9.67 mg/l | LOAEL | Not Reported | Tadpole | 10 tadpoles/replicate; 2 replicates/dose; 5 doses | Toxicity Factor Datasets | 3 wk | Laboratory |
American Kestrel (Falco sparverius)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DICOFOL | no effect | eggshell thickness for breeding female offspring of dicofol-treated females versus controls | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | decreased after 4 weeks | liver ethoxyresorufin-O-deethylase activity versus controls | Female | Adult | 4/treatment group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decrease at 125, 625 mg/kg bw (71-79%) | kidney delta aminolevulinic acid dehydratase activity | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLPARATHION | increase at 3 mg/kg bw | mortality rate 2 hr post-dose | Both Male and Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 0.367 (0.129 SE) ppm at 49 mg/d | mean lead concentration (wet wt) in liver | Female | Adult | 3/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254, MIREX | 20.3% decrease @ 8 ppm mirex + 33 ppm Aroclor | sperm concentration | Male | Adult | 5-10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PHOSPHORUS (YELLOW OR WHITE) | no effect | occurence of phosphorus intoxication symptoms | Not Reported | Adult | 4/group | Toxicity Factor Datasets | Laboratory |
Double-crested Cormorant (Phalacrocorax auritus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | increased @ all doses | hepatic EROD activity in treated embryos versus controls | Not Reported | Embryo | 83-86 eggs/treatment | Lake Winnipegosis, Manitoba | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | no effect | weight of brain, heart, liver and spleen versus controls | Not Reported | Hatchling | Not Reported | Toxicity Factor Datasets | Laboratory |
Bullfrog (Lithobates catesbeianus formerly Rana catesbeiana)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
HEXAZINONE | no effect | hatching success | Not Reported | Embryo | 20 animals/replicate; 3 replicates/dose | Toxicity Factor Datasets | embryo; midneurulation stage | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 34.4 ug/l (95% CL: 31.1 - 38.1 ug/l) | LC50 | Not Reported | Embryo | 20 animals/replicate; 4 replicates/dose | Toxicity Factor Datasets | embryo-larvae, 11d | Laboratory | |
DIELDRIN | 30.3 ug/l (95% CL: 26.2 - 35.2 ug/l) | LC50 | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | Toxicity Factor Datasets | 29 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
FLUORANTHENE | increase @ 37.97 ug/l | total distance travelled | Not Reported | Tadpole | 20/group | Toxicity Factor Datasets | Laboratory |
Deer Mouse (Peromyscus maniculatus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
GLYPHOSATE | no effect | reciprocal of hemolysin titer (against sheep rbc) | Female | Adult | 12/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLCHLORANTHRENE (3-) | 1.24 mg/kg/d | ED50 for ethoxyresorufin-O-dealkylase (EROD) activity | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 7 - 8 wk | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
MONOCROTOPHOS | 89% (2.7 SD) | mean brain cholinesterase depression (relative to control) in birds that died in 8 hrs post-dose | Both Male and Female | Adult | 15 | Toxicity Factor Datasets | Laboratory |
Clapper Rail (Rallus longirostris)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDT (4,4'-) | 42.9 ppm | mean residue concentration in brains of birds that died | Male | Juvenile | 7 birds | Toxicity Factor Datasets | Laboratory |
Mourning Dove (Zenaida macroura)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased | blood delta-aminolevulinic acid dehydratase activity | Not Reported | Not Reported | 5 birds | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Condition | Lab |
---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | increased at 10, 40 ppm | length of courtship period | Both Male and Female | Adult | 8/group | Toxicity Factor Datasets | breeding | Laboratory |