Effects of Aroclor 1254 on the thyroid gland, immune function and hepatic cytochrome P450 activity in mallards

Author(s)
Fowles, Jefferson R., Anne Fairbrother, Kimberly A. Trust and Nancy I. Kerkvliet
Year
Article Title
Effects of Aroclor 1254 on the thyroid gland, immune function and hepatic cytochrome P450 activity in mallards
Volume
75
Pages
119-129
Start Page Number
119
Final Page
129
Review

Datapoints

Displaying 1 - 5 of 5 datapoints.
Species: Mallard duck (Anas platyrhynchos)
Chemical Toxicity Endpoint Type Endpoint Description Endpoint Value Sample Size Life Cycle Stage Study Duration Type
AROCLOR 1254 TOX-Non-Repro-Sublethal - organ/system effects thyroid wt/body wt and liver wt/body wt ratios versus controls increased @ 100, 250, 500 mg/kg bw 6-12/dose Adult 5 wks Toxicity Factor Datasets
AROCLOR 1254 TOX-EXP IND - biomarkers hepatic microsomal EROD and PROD activities versus controls increased @ 20,100, 250, 500 mg/kg bw 6-12/dose Adult 5 wks Toxicity Factor Datasets
AROCLOR 1254 TOX-Non-Repro-Sublethal - organ/system effects plasma triiodothyronine concentrations versus controls decreased @ 20, 100, 250, 500 mg/kg bw 6-12/dose Adult 5 wks Toxicity Factor Datasets
AROCLOR 1254 TOX-Non-Repro-Sublethal - organ/system effects leukocyte counts, plasma biochemistry, corticosterone concentration versus controls no effect 6-12/dose Adult 5 wks Toxicity Factor Datasets
AROCLOR 1254 TOX-Non-Repro-Sublethal - organ/system effects lymphocyte proliferation to PHA versus controls increased @ 250, 500 mg/kg bw 6-12/dose Adult 5 wks Toxicity Factor Datasets

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