Birds
Mallard duck (Anas platyrhynchos)
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| MALATHION | increased @ 125 lb/acre | cumulative mortality by day 18 compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
| MALATHION | 118 (day 3), 101 (day 8) lb/acre | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
| PARATHION | 41(day 3), 39 (day 8) lb/acre | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
| DIAZINON | 74 (day 3), 79 (day 8) lb/acre LC50 | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
| PARATHION | decreased @ 7.5 lb/acre (aqueous); 0.08, 0.8 lb/acre (oil) | crown-rump length at day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
| MALATHION | decreased @ 125 lb/acre | crown-rump length at day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 8 of incubation | Laboratory | |
| DIAZINON | decreased @ 2.0 lb/acre | crown-rump length at day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 8 of incubation | Laboratory | |
| MALATHION | 49.5 lb/acre | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
| DIAZINON | 9.7 (day 3), 11.1 (day 8) lb/acre | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
| PARATHION | 2.2 (day 3), 1.5 (day 8) lb/acre | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
| DIAZINON | decreased @ 15 (aqueous), 2.0 (oil) lb/acre | embryo weight by day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
| MALATHION | decreased @ 125 (aqueous), 14.0 (oil) lb/acre | embryo weight by day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
| DIAZINON, MALATHION, PARATHION | decreased @ all doses | brain or plasma cholinesterase activity in embryos or hatchlings compared to controls | Not Reported | Embryo, Hatchling | 12/group | Toxicity Factor Datasets | Day 3 of incubation | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| ACEPHATE | 51.7% (4.82 SE) | brain cholinesterase inhibition compared with controls | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
| DICROTOPHOS | 42.8% (5.4 SE) | brain cholinesterase inhibition compared with controls | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
| FENSULFOTHION | 48.9% (7.6 SE) | brain cholinesterase inhibition compared with controls | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
| FONOFOS | 67.1% (4.9 SE) | brain cholinesterase inhibition compared with controls | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
| MALATHION | 67% (11.6 SE) | brain cholinesterase inhibition compared with controls | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
| PARATHION | 74.6% (12.4 SE) | brain cholinesterase inhibition compared with controls | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
| PARATHION | 4/36 | mortality incidence by 20 hrs post-dose | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
| MALATHION | 7/36 | mortality incidence by 20 hrs post-dose | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
| ACEPHATE | 11/36 | mortality incidence by 20 hrs post-dose | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| LEPTOPHOS | decreased @ 260 ppm | body weight growth compared with controls | Both Male and Female | Juvenile | 3-5/group | Toxicity Factor Datasets | 14 d | Laboratory | |
| LEPTOPHOS | 5/5 @ 260 ppm | incidence of ataxia | Both Male and Female | Juvenile | 3-5/group | Toxicity Factor Datasets | 14 d | Laboratory | |
| LEPTOPHOS | 4/5 @ 260 ppm | incidence of CNS lesions | Both Male and Female | Juvenile | 3-5/group | Toxicity Factor Datasets | 14 d | Laboratory |
| Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|
| see citation tables | LD50s for 42 compounds in aqueous and oil vehicles | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | incubation day 3-8 | Laboratory | |
| see citation tables | incidence of reduced growth and abnormal survivors for 42 compounds | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | incubation day 3-8 | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| EPN | decreased @ 90, 270 ppm | food consumption and body weight compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| EPN | increased @ all doses | incidence of hyperactivity, ataxia, and/or paralysis compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| EPN | increased @ 30, 90, 270 ppm | incidence of CNS lesions (demyelination, axonal degeneration in spinal cord) compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| EPN | decreased @ all doses | activity of brain and plasma cholinesterase, and brain neurotoxic esterase compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| EPN | decreased @ 90, 270 pmm | plasma alkaline phosphatase activity compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| LEPTOPHOS | decreased @ 270, 540 ppm | body weight compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| LEPTOPHOS | increased @ all doses | incidence of CNS lesions (demyelination, axonal degeneration in spinal cord) compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| LEPTOPHOS | decreased @ 270 ppm | brain weight compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| LEPTOPHOS | decreased @ all doses | activity of brain and plasma cholinesterase, and brain neurotoxic esterase compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| LEPTOPHOS | decreased @ 60, 270 ppm | plasma alkaline phosphatase activity compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| CRUDE OILS | decrease | % fertile eggs and # of ducklings; when male, female or both male and female exposed to oil, compared to control | Female | Adult | 3 pairs/dose | Toxicity Factor Datasets | 5.5 mo at initiation | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| CRUDE OILS | increase | metabolic heat production (watts/kg), compared to pre-contamination levels | Not Reported | Adult | 3/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| CRUDE OILS | 53% increase | plasma triiodothryonine concentration | Not Reported | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
| CRUDE OILS | 56% increase | hepatic cytochrome P450 content | Not Reported | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
| CRUDE OILS | no effect | body weight | Not Reported | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| DIISOPROPYL METHYLPHOSPHONATE | decrease | mean blood pressure, compared to baseline prior to exposure | Both Male and Female | Adult | 12 | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| DDE (4,4'-), DDT (4,4'-) | see citation | figure of eggshell thickness over 30 d period (significant differences noted at various times) | Female | Adult | 20/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| DDT (4,4'-) | 13.8% decrease | eggshell thickness, compared to controls | Female | Adult | 3/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| DDT (4,4'-) | decreased | eggshell weight and thickness, total eggshell calcium and shell gland epithelial microsomal Ca-ATPase activity, compared to controls | Female | Adult | 5 hens/dose; 19 eggs/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Condition | Lab |
|---|---|---|---|---|---|---|---|---|---|
| LINDANE | serum (0.13); fat (0.20); muscle (0.70); kidney (0.02); liver (0.02); brain (0.01) ppm @ 20 mg/kg 2x/wk | mean lindane residue levels | Female | Adult | 5/dose | Toxicity Factor Datasets | laying | Laboratory | |
| LINDANE | serum (0.20); fat (0.68); muscle (0.30); kidney (0.23); liver (0.14); brain (0.11) ppm @ 20 mg/kg 3x/wk | mean lindane residue levels | Female | Adult | 5/dose | Toxicity Factor Datasets | laying | Laboratory | |
| LINDANE | serum (0.50); fat (1.14); muscle (0.82); kidney (0.28); liver (0.21); brain (0.13) ppm @ 20 mg/kg 7x/wk | mean lindane residue levels | Female | Adult | 5/dose | Toxicity Factor Datasets | laying | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| DDE (4,4'-) | no effect | food consumption rate (174 g/d) compared to control (173 g/d) | Female | Adult | 10/dose | Toxicity Factor Datasets | Laboratory | |
| AROCLOR 1254 | no effect | food consumption rate (184 g/d) compared to control (173 g/d) | Female | Adult | 10/dose | Toxicity Factor Datasets | Laboratory | |
| AROCLOR 1254, DDE (4,4'-) | no effect | food consumption rate (181 g/d) compared to control (173 g/d) | Female | Adult | 10/dose | Toxicity Factor Datasets | Laboratory | |
| AROCLOR 1254 | no effect | eggshell thickness | Female | Adult | 10 hens/dose; 8-9 eggs/dose | Toxicity Factor Datasets | Laboratory | |
| DDE (4,4'-) | 17% decrease | eggshell thickness, compared to control | Female | Adult | 10 hens /dose; 8 eggs/dose | Toxicity Factor Datasets | Laboratory | |
| AROCLOR 1254, DDE (4,4'-) | 19% decrease | eggshell thickness, compared to control | Female | Adult | 10 hens/dose; 8 eggs/dose | Toxicity Factor Datasets | Laboratory | |
| AROCLOR 1254, DDE (4,4'-) | see citation | figure of # eggs/female/wk over time | Female | Adult | 10/dose | Toxicity Factor Datasets | Laboratory | |
| DDE (4,4'-) | 373 (95% CL; 152-574) ppm lipid basis @ 40 ppm diet | DDE residue concentrations in eggs | Female | Adult | 12 | Toxicity Factor Datasets | Laboratory | |
| AROCLOR 1254, DDE (4,4'-) | 344 (95% CL; 156-686) ppm DDE lipid basis and 346 (95%CL; 133-686) ppm PCB lipid basis @ 40 ppm DDE + 40 ppm PCB diet | mean DDE and PCB residue levels in eggs | Female | Adult | 13 | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| VANADYL SULFATE | no effect | body weight and food consumption compared among groups | Both Male and Female | Adult | 5 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory | |
| VANADYL SULFATE | increased @ 100 ppm (maximum = 106 +/- 19 ppb, wet wt) | vanadium concentration in blood (sampled at 3 wk intervals) | Both Male and Female | Adult | 5 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory | |
| VANADYL SULFATE | brain, 9(1); fat, 20(11); kidney, 273(49); liver, 657(113), male femur 274(47); female femur 3327(2208) ppm, wet wt | mean (SE) vanadium concentrations @ 100 ppm dose in brain, fat, kidney, liver, and femur | Both Male and Female | Adult | 5 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory | |
| VANADYL SULFATE | <0.02 ppb, wet wt @ 1, 10 ppm; 63 ppb, wet wt @ 100 ppm | vanadium concentration in eggs | Female | Adult | 5 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory | |
| VANADYL SULFATE | increased @ 100 ppm | plasma cholesterol levels in drakes and laying hens | Both Male and Female | Adult | 5 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| CRUDE OILS | increase @ 2-15 ul/egg | percent mortality versus controls | Both Male and Female | Embryo | 100 eggs/dose | Toxicity Factor Datasets | days 2-18 of incubation | Laboratory | |
| CRUDE OILS | increase @ 2-15 ul/egg | incidence of survivors with abnormalities versus controls | Both Male and Female | Embryo | 100 eggs/dose | Toxicity Factor Datasets | days 2-18 of incubation | Laboratory | |
| CRUDE OILS | decrease @ 15 ul/egg | red blood cell and liver ALAD activity and hemoglobin concentration, compared to controls | Both Male and Female | Embryo | 100 eggs/dose | Toxicity Factor Datasets | days 2-16 of incubation | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| CRUDE OILS | decrease | egg weight, length and breadth, compared to control | Female | Adult | 25/dose | Toxicity Factor Datasets | Laboratory | |
| DDE (4,4'-) | no effect | egg weight, length or breadth, compared to control | Female | Adult | 21-25/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| CRUDE OILS | decrease @ 5% | growth rate, estimated as change in body weight, compared to control | Both Male and Female | Juvenile | 50/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory | |
| CRUDE OILS | decrease @ 0.25 - 5% | distance retreated from a frightening stimulus; impaired avoidance behavior | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-6 d post-hatch | Laboratory | |
| CRUDE OILS | increase @ 2.5 - 5% | incidence of liver hypertrophy and splenic atropy | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory | |
| CRUDE OILS | decrease @ 2.5 - 5% | hematocrit, compared to control | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory | |
| CRUDE OILS | increase @ 0.25 - 5.0% | plasma alanine aminotransferase activity, from liver | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory | |
| CRUDE OILS | increase @ 0.025 - 5% | pathological release of ornithine carbamyltransferase from kidney | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory | |
| CRUDE OILS | increase @ 5% | incidence of degeneration of kidney tubules | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| LEAD (elemental) | decreased | body weight and delta-aminolevulinic acid dehydratase activity versus controls | Male | Adult | 20/treatment group | Toxicity Factor Datasets | Laboratory | |
| LEAD (elemental) | increased | erythrocyte protoporphyrin concentrations versus controls | Male | Adult | 20/treatment group | Toxicity Factor Datasets | Laboratory | |
| LEAD (elemental) | no effect | body weight and hematocrit versus controls | Male | Juvenile | 20/treatment group | Toxicity Factor Datasets | Laboratory | |
| LEAD (elemental) | 60% @ 2 shot, 30% @ 4 shot | cumulative mortality | Male | Adult | 10/treatment group | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | California Counties | Lab |
|---|---|---|---|---|---|---|---|---|---|---|
| LEAD (elemental) | increased @ 2 #four shot | mortality versus controls | Both Male and Female | Adult | 12 (control); 16 (lab); 63 (field) | Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | Laboratory |
| LEAD (elemental) | decreased @ 931,000 shot/acre or 2 #four pellets | spleen weight and total white blood cell counts versus controls | Both Male and Female | Adult | 12 (control); 16 (lab); 63 (field) | Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | Laboratory |
| LEAD (elemental) | ppm wet wt: 3.47 (1.38), blood; 32.16 (11.60), liver; 114.78 (28.96), femur @ 2 #four shot | mean (2SE) lead concentration in liver, femur and blood | Male | Adult | 11 birds | Toxicity Factor Datasets | 1 yr | Laboratory | ||
| LEAD (elemental) | ppm wet wt: 4.15 (3.56), blood; 13.85 (7.96), liver; 577.07 (156.4), femur@ 2 #four shot | mean (2SE) lead concentrations in liver, femur and blood | Female | Adult | 5 birds | Toxicity Factor Datasets | 1 yr | Laboratory | ||
| LEAD (elemental) | decreased @ 2 #four shot | spleen plaque forming cell counts, % packed cell volume versus controls | Both Male and Female | Adult | 16 (2 #four shot) 63 (field exposure) |
Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| IRON (elemental), LEAD (elemental) | increased @ 8 #four iron shot | serum glutamic pyruvic transaminase activity vs controls | Female | Adult | 8/group | Toxicity Factor Datasets | Laboratory | |
| IRON (elemental), LEAD (elemental) | increased with all treatments | incidence of hemosiderosis in liver vs controls | Female | Adult | 8/group | Toxicity Factor Datasets | Laboratory | |
| IRON (elemental), LEAD (elemental) | increased @ 8 #four iron shot | incidence of inclusion bodies in kidney vs controls | Female | Adult | 8/group | Toxicity Factor Datasets | Laboratory | |
| IRON (elemental), LEAD (elemental) | no effect | serum enzyme levels versus controls (at 30 or 60 d post dose) | Male | Adult | 2/group | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
|---|---|---|---|---|---|---|---|---|
| LEAD (elemental) | decreased @ > 60 ug/dl blood | delta-aminolevulinic acid dehydratase activity | Both Male and Female | Not Reported | 21 birds | World Wildlife Fund Refuge, Tuscany | Toxicity Factor Datasets | ITALY |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| LEAD (elemental) | increased @ 7, 14, 21 d post-dose | concentration of lead in blood versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory | |
| LEAD (elemental) | no effect | body weight versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory | |
| LEAD (elemental) | increased @ 1 #four shot | mortality rate by 15 d post-dose versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory | |
| LEAD (elemental) | decreased @ 1 #four shot, 7, 14, 21 d. post-dose | agglutination titers to sheep red blood cells versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
|---|---|---|---|---|---|---|---|
| ENDRIN | breast muscle=non-detect.; liver=non-detect.-0.05; fat=non-detect.-0.50 ppm, wet wt | tissue endrin residues | Not Reported | Not Reported | 7-10 animals | Wenatchee | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| LEAD NITRATE | no effect (3 or 8 d) | open field behavior scores versus controls | Not Reported | Juvenile | 26-28/group | Toxicity Factor Datasets | 9 d | Laboratory | |
| LEAD NITRATE | decreased @ 5 ppm (8 d exposure) | mean percentage weight gain versus controls | Not Reported | Juvenile | 26-28/group | Toxicity Factor Datasets | 9 d | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| EPN | decreased @ 12 ug/g (82%); 36 ug/g (77%); 108 ug/g (70%) | percent survival versus controls | Not Reported | Embryo | 10/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory | |
| EPN | decreased @ 12, 36, 108 ug/g | brain weight, acetylcholinesterase activity, neurotoxic esterase activity versus controls | Not Reported | Embryo | 10/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory | |
| EPN | decreased @ 108 ug/g | brain protein content versus controls | Not Reported | Embryo | 10/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory | |
| EPN | decreased @ 36 (cholineserase only), 108 ug/g | plasma alkaline phosphatase, aspartate aminotransferase, cholinesterase activities, and uric acid | Not Reported | Embryo | 12/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory |