Dose-Response Table

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Displaying 398 data points

Bullfrog (Lithobates catesbeianus formerly Rana catesbeiana)

Citation:

Teratogenesis, toxicity and bioaccumulation in frogs exposed to dieldrin

Author(s)
Schuytema, Gerald S., Alan V. Nebeker, William L. Griffis and Karsten N. Wilson
Pages
332-350
Year
Volume
21
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
DIELDRIN 360 - 900 range of bioconcentration factors; calculated by dividing the whole body tissue dieldrin concentration by water dieldrin concentration Not Reported Tadpole 20 animals/replicate; 4 replicates/dose Toxicity Factor Datasets 29 d Laboratory
DIELDRIN 36,000 - 90,000 range of lipid bioconcentration factors; calculated by dividing the whole body bioconcentration values x 100 by percent lipid Not Reported Tadpole 20 animals/replicate; 4 replicates/dose Toxicity Factor Datasets 29 d Laboratory
Citation:

Acid tolerance of anuran embryos and larvae from central Ontario

Author(s)
Grant, Karen P. and Lawrence E. Licht
Pages
1-6
Year
Issue
1
Volume
27
Chemical Endpoint Value Sex Life Cycle Stage Sample Size Location Type Lab
SULFURIC ACID significant increase at pH 3.5 and 4.0 Not Reported Tadpole 120 animals/dose Toxicity Factor Datasets Laboratory

Double-crested Cormorant (Phalacrocorax auritus)

Citation:

Effects of 3,3',4,4',5-pentacholorobiphenyl (PCB 126), 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), or an extract derived from field-collected cormorant eggs injected into double-crested cormorant (Phalacrocorax auritus) eggs

Author(s)
Powell, Debra C., Richard J. Aulerich, John C. Meadows, Donald E. Tillit, Jon F. Powell, Janelle C. Restum, Kenneth L. Stromborg, John P. Giesy and Steven J. Bursian
Pages
1450-1455
Year
Issue
7
Volume
16
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) increased at 4.0 ug/kg egg incidence of embryo mortality versus controls Not Reported Hatchling 58-60/group Toxicity Factor Datasets Laboratory

Mourning Dove (Zenaida macroura)

Citation:

Chronic toxicity of methiocarb to grackles, doves and quail and reproductive effects in quail

Author(s)
Schafer, E.W., Jr., R.B. Brunton, N.F. Lockyer and D.J. Cunningham
Pages
641-647
Year
Issue
6
Volume
14
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
METHIOCARB decreased at all doses food consumption Not Reported Not Reported 6/group Toxicity Factor Datasets Laboratory
Citation:

Survival and cover-seeking response of northern bobwhites and mourning doves dosed with aldicarb`

Author(s)
Hawkes, Anthony W., Larry W. Brewer, James F. Hobson, Michael J. Hooper and Ronald J. Kendall
Pages
1538-1543
Year
Issue
9
Volume
15
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
ALDICARB no effect daily survival rate in dosed wild birds Not Reported Adult 9-12/group Toxicity Factor Datasets Laboratory
Citation:

Effects of lead shot ingestion on captive mourning dove survivability and reproduction

Author(s)
Buerger, Theodore T., Ralph E. Mirarchi and Michael E. Lisano
Pages
1-8
Year
Issue
1
Volume
50
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
LEAD (elemental) increased at all doses mortality Not Reported Adult 25 birds/dose Toxicity Factor Datasets Laboratory

American Kestrel (Falco sparverius)

Citation:

Survival, growth, and histopathological effects of paraquat ingestion in nestling American kestrels (Falco sparverius)

Author(s)
Hoffman, David J., J. Christian Franson, Oliver H. Pattee and Christine M. Bunck
Pages
495-500
Year
Volume
14
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
PARAQUAT 22% @ 10 mg/kg, 18% @ 25 mg/kg, 44% @ 60 mg/kg percent mortality Not Reported Juvenile 11/group Toxicity Factor Datasets Laboratory
PARAQUAT 86% of control @ 25 mg/kg, 74% of control @ 60 mg/kg body weight by 10 days of dosing Not Reported Juvenile 11/group Toxicity Factor Datasets Laboratory
PARAQUAT 11% @ 25 mg/kg, 25% @ 60 mg/kg percent increase over controls in brain to body weight ratio Not Reported Juvenile 11/group Toxicity Factor Datasets Laboratory
PARAQUAT 14% @ 25 mg/kg, 18% @ 60 mg/kg percent increase over controls in liver to body weight ratio Not Reported Juvenile 11/group Toxicity Factor Datasets Laboratory
Citation:

Developmental Toxicity of PCB 126 (3,3',4,4',5-Pentachlorobiphenyl) in nestling American kestrels (Falco sparverius)

Author(s)
Hoffman, David J., Mark J. Melancon, Patrice N. Klein, Clifford P. Rice, John D. Eisemann, Randy K. Hines, James W. Spann, and Grey W. Pendleton
Pages
188-200
Year
Volume
34
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) no effect hematocrit and hemoglobin values versus controls Not Reported Nestling 9-11/group Toxicity Factor Datasets Day 1-Day 10 Laboratory
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) increased @ 50,250,1000 ng/g bw hepatic monooxygenase activities versus controls Not Reported Nestling 9-11/group Toxicity Factor Datasets Day 1-Day 10 Laboratory
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) in ng/g, wet wt: 156 (@ 50 ng/g), 380 (@ 250 ng/g), 1098 (@1000 ng/g) concentration in liver Not Reported Nestling 9-11/group Toxicity Factor Datasets Day 1-Day 10 Laboratory
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) positive correlation relationship between hepatic PCB 126 concentrations and ratio of oxidized to reduced glutathione Not Reported Nestling 9-11/group Toxicity Factor Datasets Day 1-Day 10 Laboratory
Citation:

Comparative developmental toxicity of planar polychlorinated biphenyl congeners in chickens, American kestrels, and common terns

Author(s)
Hoffman, David J., Mark J. Melancon, Patrice N. Klein, John D. Eisemann, and James W. Spann
Pages
747-757
Year
Issue
4
Volume
17
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) increased @ 2.3, 23, 233 ng/g incidence of malformations or edema, and EROD activity versus controls Not Reported Hatchling 24-26/treatment group Toxicity Factor Datasets hatchling Laboratory
PCB 77 (3,3',4,4'-TETRACHLOROBIPHENYL) reduced @ 100, 1000 ng/g percent hatching success, percent pipped versus controls Not Reported Hatchling 24-26/treatment group Toxicity Factor Datasets hatchling Laboratory
PCB 77 (3,3',4,4'-TETRACHLOROBIPHENYL) reduced @ 1000 ng/g humerus length versus controls Not Reported Hatchling 24-26/treatment group Toxicity Factor Datasets hatchling Laboratory
PCB 77 (3,3',4,4'-TETRACHLOROBIPHENYL) increased @ 100, 1000 ng/g incidence of malformations or edema, and EROD activity versus controls Not Reported Hatchling 24-26/treatment group Toxicity Factor Datasets hatchling Laboratory
Citation:

Selenium accumulation and effects on reproduction in captive American kestrels fed selenomethionine

Author(s)
Santolo, Gary M., Julie T. Yamamoto, Jacqueline M. Pisenti, Barry W. Wilson
Pages
502-511
Year
Issue
2
Volume
63
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
SELENOMETHIONINE no effect incidence of embryo deformities versus controls Both Male and Female Adult 15 pairs/treatment group; 10 control pairs Toxicity Factor Datasets Laboratory
SELENOMETHIONINE no effect chick mass and size at hatch, and chick survival to fledging versus controls Both Male and Female Adult, Juvenile 15 pairs/treatment group; 10 control pairs Toxicity Factor Datasets Laboratory
Citation:

Parathion accumulation in cricket frogs and its effect on American kestrels

Author(s)
Fleming, W. James, Haydee de Chacin, Oliver H. Pattee and Thair G. Lamont
Pages
921-927
Year
Volume
10
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
PARATHION 25% at 4.6 ppm Not Reported Adult 4/group Toxicity Factor Datasets Laboratory
PARATHION 47% decrease at 4.6 ppm mean brain cholinesterase activity relative to control Not Reported Adult 4/group Toxicity Factor Datasets Laboratory
Citation:

Methyl parathion and fenvalerate toxicity in American kestrels: acute physiological responses and effects of cold

Author(s)
Rattner, Barnett A. and J. Christian Franson
Pages
787-792
Year
Volume
62
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
METHYLPARATHION increase at 3 mg/kg bw mortality rate 2 hr post-dose Both Male and Female Adult 5/dose Toxicity Factor Datasets Laboratory
Citation:

The effect of dietary sodium fluoride on internal organs, breast muscle, and bones in captive American kestrels (Falco sparverius)

Author(s)
Bird, D.M., D. Carriere and D. Lacombe
Pages
242-246
Year
Volume
22
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
FLUORIDE, SODIUM 247.0 +/- 103.1 ppm @ 0 ppm; 6137.9 +/- 823.8 ppm @ 1120 ppm; 10,272.6 +/- 865.8 ppm @ 2240 ppm mean fluoride content in the diaphyses of femurae Both Male and Female Juvenile 9-10/group Toxicity Factor Datasets 7 d Laboratory
FLUORIDE, SODIUM increased at 1120, 2240 ppm % bone ash Both Male and Female Juvenile 9-10/group Toxicity Factor Datasets 7 d Laboratory

Mallard duck (Anas platyrhynchos)

Citation:

DDT thins shells of eggs from mallard ducks maintained on ad libitum or controlled-feeding regimes

Author(s)
Davison, K.L. and J.L. Sell
Pages
222-232
Year
Volume
2
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
DDT (4,4'-) decrease @ 20 - 200 ppm eggshell thickness, weight and calcium concentration Female Adult 18/dose Toxicity Factor Datasets Laboratory
DIELDRIN 6% decrease @ 10 ppm eggshell thickness Female Adult 18/dose Toxicity Factor Datasets Laboratory
Citation:

Effect of asulam in wildlife species: Acute toxicity to birds and fish

Author(s)
Ingham, Brian and Michael A. Gallo
Pages
194-199
Year
Issue
2
Volume
13
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
ASULAM decreased @ all doses body weight gain by day 8 compared with controls Both Male and Female Juvenile 10/dose Toxicity Factor Datasets 7 d Laboratory
DDT (4,4'-) decreased @ all doses food consumption compared with controls Both Male and Female Juvenile 10/dose Toxicity Factor Datasets 7 d Laboratory
DDT (4,4'-) decreased @ all doses body weight gain by 8 days compared with controls Both Male and Female Juvenile 10/dose Toxicity Factor Datasets 7 d Laboratory
DDT (4,4'-) 1550 ppm 5 day dietary LC50 Both Male and Female Juvenile 10/dose Toxicity Factor Datasets 7 d Laboratory
Citation:

Effects of malathion, diazinon, and parathion on mallard embryo development and cholinesterase activity

Author(s)
Hoffman, David J. and William C. Eastin, Jr.
Pages
472-485
Year
Volume
26
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
MALATHION decreased @ 125 (aqueous), 14.0 (oil) lb/acre embryo weight by day 18 of incubation compared with controls Not Reported Embryo 30/group Toxicity Factor Datasets Day 3 or 8 of incubation Laboratory
DIAZINON, MALATHION, PARATHION decreased @ all doses brain or plasma cholinesterase activity in embryos or hatchlings compared to controls Not Reported Embryo, Hatchling 12/group Toxicity Factor Datasets Day 3 of incubation Laboratory
Citation:

Subchronic organophosphorus ester-induced delayed neurotoxicity in mallards

Author(s)
Hoffman, David J., Louis Sileo and Helen C. Murray
Pages
128-136
Year
Volume
75
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
LEPTOPHOS decreased @ 270, 540 ppm body weight compared with controls Female Juvenile 6/group Toxicity Factor Datasets 20 wks Laboratory
LEPTOPHOS increased @ all doses incidence of CNS lesions (demyelination, axonal degeneration in spinal cord) compared with controls Female Juvenile 6/group Toxicity Factor Datasets 20 wks Laboratory
LEPTOPHOS decreased @ 270 ppm brain weight compared with controls Female Juvenile 6/group Toxicity Factor Datasets 20 wks Laboratory
LEPTOPHOS decreased @ all doses activity of brain and plasma cholinesterase, and brain neurotoxic esterase compared with controls Female Juvenile 6/group Toxicity Factor Datasets 20 wks Laboratory
Citation:

Neurotoxic and teratogenic effects of an organophosphorus insecticide (phenyl phosphorothioic acid-o-ethyl-o-[4-nitrophenyl] ester) on mallard development

Author(s)
Hoffman, David J. and Louis Sileo
Pages
284-294
Year
Volume
73
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
EPN decreased @ 12, 36, 108 ug/g brain weight, acetylcholinesterase activity, neurotoxic esterase activity versus controls Not Reported Embryo 10/group Toxicity Factor Datasets 72 hr of incubation (time of treatment) Laboratory
EPN decreased @ 108 ug/g brain protein content versus controls Not Reported Embryo 10/group Toxicity Factor Datasets 72 hr of incubation (time of treatment) Laboratory
EPN decreased @ 36 (cholineserase only), 108 ug/g plasma alkaline phosphatase, aspartate aminotransferase, cholinesterase activities, and uric acid Not Reported Embryo 12/group Toxicity Factor Datasets 72 hr of incubation (time of treatment) Laboratory
EPN decreased @ 12, 36, 108 ug/g embryo weight and length, % normal survivors versus controls Not Reported Embryo 12/group Toxicity Factor Datasets 72 hr of incubation (time of treatment) Laboratory
Citation:

Effects of industrial effluents, heavy metals, and organic solvents on mallard embryo development

Author(s)
Hoffman, David J. and William C. Eastin, Jr.
Pages
35-40
Year
Volume
9
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
FUEL OILS decreased @ 0.5 ul/egg, incubation day 3 or 8 exposure embyronic length and weight by incubation day 18 versus controls Not Reported Embryo 30 eggs/group Toxicity Factor Datasets 3 or 8 days of incubation (time of treatment) Laboratory
FUEL OILS decreased @ 2% emulsion, incubation day 8 exposure embryo survival through day 18 of incubation versus controls Not Reported Embryo 30 eggs/group Toxicity Factor Datasets 3 or 8 days of incubation (time of treatment) Laboratory
ACETONE decreased @ 100% solution, incubation days 3 or 8 exposure embryo weight and length by incubation day 18 versus controls Not Reported Embryo 30 eggs/group Toxicity Factor Datasets 3 or 8 days of incubation (time of treatment) Laboratory
ACETONE decreased @ 100% solution, incubation days 3 or 8 exposure embryo survival through incubation day 18 versus controls Not Reported Embryo 30 eggs/group Toxicity Factor Datasets 3 or 8 days of incubation (time of treatment) Laboratory
Citation:

Histopathologic efffects of dietary cadmium on kidneys and testes of mallard ducks

Author(s)
White, Donald H., Mack T. Finley and John F. Ferrell
Pages
551-558
Year
Volume
4
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
CADMIUM CHLORIDE increased @ 200 ppm incidence of testes alterations (atrophy, decreased spermatogenesis) versus controls Male Adult 5 birds Toxicity Factor Datasets first year Laboratory
CADMIUM CHLORIDE 0.46 (@ 0 ppm), 4.63 (@ 2 ppm), 54.33 (@ 20 ppm), 77.22 (@ 200 ppm) ppm, wet wt mean Cd concentrations in kidneys (ppm, wet wt) by 90 days Both Male and Female Adult 10 birds Toxicity Factor Datasets first year Laboratory
CADMIUM CHLORIDE 0.03 (@ 0 ppm), 0.02 (@ 2 ppm), 0.72 (@ 20 ppm) 8.47 (@ 200 ppm) ppm, wet wt mean Cd concentrations in testes (ppm, wet wt) by 90 days Male Adult 5 birds Toxicity Factor Datasets first year Laboratory
Citation:

Acid precipitation and food quality: effects of dietary Al, Ca, and P on bone and liver characteristics in American black ducks and mallards

Author(s)
Sparling, Donald W.
Pages
281-288
Year
Volume
21
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
ALUMINUM SULFATE see table Ca, Al, P concentrations in femur for different treatments after 2 and 10 wks of treatment Not Reported Juvenile 12-14/group Toxicity Factor Datasets Laboratory
ALUMINUM SULFATE decreased on LL and LH diets femur mass and mean breaking force (LL, LH vs. NN diets) after 2 wks of treatment Not Reported Juvenile 12-14/group Toxicity Factor Datasets Laboratory
ALUMINUM SULFATE decreased with LL and LH diets femur breaking strength (LL,LH vs. NN diets) after 10 wks of treatment Not Reported Juvenile 12-14/group Toxicity Factor Datasets Laboratory
ALUMINUM SULFATE increased in LL diets incidence of clinical signs (LL vs. LH vs. NN diets) Not Reported Juvenile 12-14/group Toxicity Factor Datasets Laboratory
Citation:

Uptake and retention of dietary cadmium in mallard ducks

Author(s)
White, Donald H. and Mack T. Finley
Pages
53-59
Year
Volume
17
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
CADMIUM CHLORIDE increased to 0.010 (@ 20 ppm), 0.040 (@ 200 ppm) ppm, wet wt Cd concentrations in eggs versus controls Both Male and Female Adult 15 eggs (20 ppm), 3 eggs (200 ppm) Toxicity Factor Datasets 1 yr Laboratory
CADMIUM CHLORIDE increased @ 200 ppm/60 or 90 d of treatment, 30 d post-treatment mean kidney weight versus controls Both Male and Female Adult 10 kidneys/group Toxicity Factor Datasets 1 yr Laboratory
CADMIUM CHLORIDE decreased @ all doses/30 d post-treatment, and 200 ppm/90 d of treatment mean testis weight versus controls Male Adult 5 testes/group Toxicity Factor Datasets 1 yr Laboratory
Citation:

Teratogenic effects of external egg applications of methyl mercury in the mallard, Anas platyrynchos

Author(s)
Hoffman, David J. and John M. Moore
Pages
453-462
Year
Volume
20
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
METHYLMERCURY CHLORIDE decreased @ 9, 27, 90 ug Hg % survival by day 18 of incubation versus controls Both Male and Female Embryo 80 eggs/group Toxicity Factor Datasets incubation day 3 Laboratory
Citation:

Sublethal effects of cadmium ingestion on mallard ducks

Author(s)
Di Giulio, Richard T. and Patrick F. Scanlon
Pages
765-771
Year
Volume
13
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
CADMIUM CHLORIDE decreased @ 450 ppm liver aldolase activity, plasma triiodothyronine levels Not Reported Adult 12 birds/group Toxicity Factor Datasets 1 yr Laboratory
Citation:

Interactive effects of boron, selenium, and dietary protein on survival, growth, and physiology in mallard ducklings

Author(s)
Hoffman, David J., Caroline J. Sanderson, Leonard J. LeCaptain, Eugene Cromartie and Grey W. Pendleton
Pages
288-294
Year
Volume
20
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
BORIC ACID, SELENOMETHIONINE decreased @ 1000 ppm B hematocrits and hemoglobin concentrations versus controls Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
BORIC ACID, SELENOMETHIONINE decreased @ 15 ppm Se (with or w/out B), and 1000 ppm B hematocrits and hemoglobin concentrations versus controls Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
BORIC ACID, SELENOMETHIONINE 10.8 (@ 15 ppm Se), 56.0 (@ 60 ppm) ppm Se, wet wt
11.0 (@ 1000 ppm B) ppm B, wet wt 		geometric mean Se and B concentrations in liver Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
BORIC ACID, SELENOMETHIONINE 22.5 (@ 15 ppm Se w/out B), 41.9 (@ 15 ppm Se w/B) ppm Se, wet wt
13.0 (@ 1000 ppm B) ppm B, wet wt 		geometric mean Se and B concentrations in liver Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
Citation:

Diagnostic criteria for selenium toxicosis in aquatic birds: Dietary exposure, tissue concentrations and macroscopic effects

Author(s)
Albers, Peter H., D. Earl Green and Caroline J. Sanderson
Pages
468-485
Year
Volume
32
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
SELENOMETHIONINE increased in birds that died incidence of macroscopic abnormalities versus controls Male Adult 21/dose Toxicity Factor Datasets 1 yr Laboratory
SELENOMETHIONINE increased @ 40 ppm incidence of macroscopic abnormalities of muscles, claws and feathers versus controls Male Adult 21/dose Toxicity Factor Datasets 1 yr Laboratory
SELENOMETHIONINE decreased in birds that died mean weights of heart, spleen, pancreas, testis versus controls Male Adult 21/dose Toxicity Factor Datasets 1 yr Laboratory
SELENOMETHIONINE 33(7) ppm @ 10 ppm Se, 49(9) ppm @ 20 ppm Se, 87(11) ppm @ 40 ppm Se, 99(9) ppm in birds that died mean (SE) dry wt concentrations of selenium in liver Male Adult 10-25 Toxicity Factor Datasets 1 yr Laboratory
Citation:

Effects of boron and selenium on mallard reproduction and duckling growth and survival

Author(s)
Stanley, Thomas R., Jr., Gregory J. Smith, David J. Hoffman, Gary H. Heinz, and Roger Rosscoe
Pages
1124-1132
Year
Issue
7
Volume
15
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
BORIC ACID, SELENOMETHIONINE reduced @ 900 ppm B body weight and growth at 0, 7,and 14 days post-hatch versus controls Both Male and Female Juvenile 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE reduced @ 7 ppm Se body weight and weight gain at 7 and 14 days post-hatch versus 3.5 ppm Se group Both Male and Female Juvenile 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE increased @ 3.5 ppm Se survival between 7 and 14 days post-hatch versus controls Both Male and Female Juvenile 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE reduced @ 7 ppm duckling production versus 3.5 ppm Se group Both Male and Female Both Adults and Juveniles 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
Citation:

Toxicity of lead-contaminated sediment to mallards

Author(s)
Heinz, G.H., D.J. Hoffman, L. Sileo, D.J. Audet, and L.J. LeCaptain
Pages
323-333
Year
Volume
36
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
LEAD COMPOUNDS increased @ 642 and 1284 ug/g occurrence of renal tubular nuclear inclusion bodies versus controls Male Adult 10/ Pb treatment; 5/control treatment Toxicity Factor Datasets approx. 5 mo Laboratory
LEAD COMPOUNDS 3.0(0.30) ppm @ 642 ug/g Pb; 6.8(0.84) ppm @ 1284 ug/g Pb mean (SE) wet wt Pb concentrations in blood Male Adult 10/ Pb treatment; 5/control treatment Toxicity Factor Datasets approx. 5 mo Laboratory
LEAD COMPOUNDS 9.1(0.61) ppm @ 642 ug/g Pb; 16(1.5) ppm @ 1284 ug/g Pb mean (SE) wet wt Pb concentrations in liver Male Adult 10/ Pb treatment; 5/control treatment Toxicity Factor Datasets approx. 5 mo Laboratory
LEAD COMPOUNDS reduced @ 869 ug/g, corn diet hemoglobin concentration versus corn diet controls Male Adult 5/ Pb treatment;3/control treatments Toxicity Factor Datasets approx. 7 mo Laboratory
Citation:

Toxic, neurochemical and behavioral effects of dieldrin exposure in mallard ducks

Author(s)
Sharma, R.P., D.S. Winn and J.B. Low
Pages
43-53
Year
Issue
1
Volume
5
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
DIELDRIN increased @ 30 ppm liver protein concentration versus controls Both Male and Female Juvenile 5-15 per group Toxicity Factor Datasets 75 days Laboratory
DIELDRIN increased @ 10, 30 ppm liver DNA content versus controls Male Both Adults and Juveniles 5-15 per group Toxicity Factor Datasets 75 days Laboratory
DIELDRIN decreased @ all doses % drake encounter scores Male Both Adults and Juveniles 30 per group Toxicity Factor Datasets Laboratory
Citation:

Genetic response of mallards to toxic effects of methyl mercuric chloride

Author(s)
Prince, H.H.
Pages
31-40
Publisher
American Society for Testing and Materials
Year
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
METHYLMERCURY CHLORIDE decreased hatchability versus controls Not Reported Juvenile 29 pairs Toxicity Factor Datasets Laboratory
Citation:

Effects of dietary cadmium on mallard ducklings

Author(s)
Cain, Brian W., Lou Sileo, J. Christian Franson and John Moore
Pages
286-297
Year
Volume
32
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
CADMIUM CHLORIDE decreased @ 20 ppm packed cell volume and hemoglobin concentration by 8 wks of treatment compared to controls Not Reported Juvenile 12 birds per timexdose treatment day old Toxicity Factor Datasets Laboratory
CADMIUM CHLORIDE increased @ 20 ppm incidence of kidney lesions by 12 wks of treatment compared to controls Not Reported Juvenile 12 birds per timexdose treatment day old Toxicity Factor Datasets Laboratory
CADMIUM CHLORIDE increased @ 20 ppm serum glutamic pyruvic transaminase activity by 8 wks of treatment compared to controls Not Reported Juvenile 12 birds per timexdose treatment day old Toxicity Factor Datasets Laboratory
Citation:

Subacute dietary toxicities of dicrotophos and dieldrin in time-replicated trials with young ring-necked pheasants and mallards

Author(s)
Hill, E.F.
Pages
105-120
Publisher
American Society for Testing and Materials
Year
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
DICROTOPHOS 101.8 (coeff. of variation = 21.6%) 5 day dietary LC50 Not Reported Juvenile 8-10/dose Toxicity Factor Datasets 5 days Laboratory
DIELDRIN 155.8 (coeff. of variation = 16.0%) 5 day dietary LC50 Not Reported Juvenile 8-10/dose Toxicity Factor Datasets 5 days Laboratory
Citation:

Recovery of cholinesterase activity in mallard ducklings administered organophosphorus pesticides

Author(s)
Fleming, W. James and Steven P. Bradbury
Pages
885-897
Year
Volume
8
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
ACEPHATE 51.7% (4.82 SE) brain cholinesterase inhibition compared with controls Not Reported Juvenile 36/dose Toxicity Factor Datasets 14 d Laboratory
DICROTOPHOS 42.8% (5.4 SE) brain cholinesterase inhibition compared with controls Not Reported Juvenile 36/dose Toxicity Factor Datasets 14 d Laboratory
Citation:

Hepatic glutathione metabolism and lipid peroxidation in response to excess dietary selenomethionine and selenite in mallard ducklings

Author(s)
Hoffman, David J., Gary H. Heinz and Alexander J. Krynitsky
Pages
263-271
Year
Volume
27
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
SELENOMETHIONINE increased @ 10,20,40 ppm incidence of altered hepatic glutathione metabolism versus controls Not Reported Juvenile 40 birds/group Toxicity Factor Datasets day old Laboratory
SELENITE, SODIUM increased @ 10,20,40 ppm incidence of altered hepatic glutathione metabolism versus controls Not Reported Juvenile 40 birds/group Toxicity Factor Datasets day old Laboratory
Citation:

Delayed neurotoxicity in the wild mallard duckling caused by organophosphorus insecticides cyanofenphos and leptophos

Author(s)
Soliman, S.A., N.S. Ahmed, K.S. El-Gendy, A.S. El-Bakary and A.H. El-Sebae
Pages
401-411
Year
Issue
5
Volume
B21
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
CYANOFENPHOS increased incidence of delayed neurotoxicity signs Both Male and Female Juvenile 10 laboratory Toxicity Factor Datasets 1 week Laboratory
CYANOFENPHOS increased (30% @ 10 mg leptophos/kg/d; 10% @ 0.5 mg cyanofenphos/kg/d; 0% @ 1.0 mg cyanofenphos/kg/d; 20% @ 2.0 mg cyanofenphos/kg/d ;60% @ 4.0 mg cyanofenphos/kg/d; 100% @ 8.0 mg cyanofenphos/kg/d mortality versus controls) Both Male and Female Juvenile 10 laboratory Toxicity Factor Datasets 1 week Laboratory
Citation:

Interactive effects of arsenate, selenium, and dietary protein on survival, growth, and physiology in mallard ducklings

Author(s)
Hoffman, David J., Caroline J. Sanderson, Leonard J. LeCaptain, Eugene Cromartie and Grey W. Pendleton
Pages
55-62
Year
Volume
22
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
ARSENATE, SODIUM, SELENOMETHIONINE increased (40%) @ 60 ppm Se incidence of mortality versus controls Not Reported Juvenile 15 birds/group Toxicity Factor Datasets 1 d Laboratory
Citation:

Toxic effects of natural saline waters on mallard ducklings

Author(s)
Mitcham, S.A. and G. Wobeser
Pages
45-50
Year
Issue
1
Volume
24
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
SALINE WATER decreased @ 4000 or 7720 umhos/cm body weight by day 14 or 16 versus controls Not Reported Juvenile 10 birds/group Toxicity Factor Datasets 2 d Laboratory

Long-toed Salamander (Ambystoma macrodactylum)

Citation:

Methoxychlor alters hatching and larval startle response in the salamander Ambystoma macrodactylum

Author(s)
Ingermann, R.L., D.C. Bencic and V.P. Eroschenko
Pages
815-821
Year
Volume
59
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
METHOXYCHLOR no appreciable mortality embryo and larvae (10 d post-hatch) mortality Not Reported Embryo, Juvenile 30-34 eggs/dose Toxicity Factor Datasets Laboratory
METHOXYCHLOR decrease @ 0.3 and 10 mg/L mean body weight of larvae Not Reported Embryo, Juvenile 30-38 eggs/dose Toxicity Factor Datasets Laboratory

Merriam's Kangaroo Rat (Dipodomys merriami)

Citation:

Effects of low OP dose on seed/bead discrimination in the kangaroo rat, Dipodomys

Author(s)
Peterle, T. J. and R. Bentley
Pages
95-100
Year
Volume
43
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
METHYLPARATHION 97.1 mg/kg (95% CI, 42.6-178.6 mg/kg) LD50 Both Male and Female Adult 3-4 animals/group Toxicity Factor Datasets Laboratory

Killdeer (Charadrius vociferus)

Citation:

Effects of carbaryl grasshopper control on nesting killdeer in North Dakota

Author(s)
Fair, Jeanne M, Patricia L. Kennedy and Lowell C. McEwen
Pages
881-890
Year
Issue
5
Volume
14
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type
CARBARYL no effect brain acetylcholinesterase activity Not Reported Not Reported 6-13 birds/group Toxicity Factor Datasets

Pacific Treefrog (Pseudacris regilla formerly Hyla regilla)

Citation:

Comparative effects of ammonium and nitrate compounds on Pacific treefrog and African clawed frog embryos

Author(s)
Schuytema, G.S. and A.V. Nebeker
Pages
200-206
Year
Volume
36
Chemical Endpoint Value Endpoint Description Units Sex Life Cycle Stage Sample Size Location Type Error Lab
AMMONIUM NITRATE 25.0 10-d LC50 value for embryos mg/L as NH4-N Not Reported Embryo 10/replicate; 3 replicates/dose Toxicity Factor Datasets 21.9-28.7 (95% CI) Laboratory
AMMONIUM NITRATE 6.9 LOAEL for body weight and length mg NH4-N/L Not Reported Embryo 10/replicate; 3 replicates/dose Toxicity Factor Datasets Laboratory

Deer Mouse (Peromyscus maniculatus)

Citation:

Comparative toxicity of azinophos-methyl to house mice, laboratory mice, deer mice and gray-tailed voles

Author(s)
Meyers, S.M. and J.O. Wolff
Pages
478-482
Year
Volume
26
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
AZINPHOS-METHYL (GUTHION) 48 mg/kg bw (95% CL: 39-74 mg/kg, slope = 2.57 +/- 0.73SE) LD50 Male Adult 5-7 animals/dose Toxicity Factor Datasets Laboratory
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