Aquatic birds
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease @ 5% | growth rate, estimated as change in body weight, compared to control | Both Male and Female | Juvenile | 50/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory | |
CRUDE OILS | decrease @ 0.25 - 5% | distance retreated from a frightening stimulus; impaired avoidance behavior | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-6 d post-hatch | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
IRON (elemental), LEAD (elemental) | increased @ 8 #four iron shot | serum glutamic pyruvic transaminase activity vs controls | Female | Adult | 8/group | Toxicity Factor Datasets | Laboratory | |
IRON (elemental), LEAD (elemental) | increased with all treatments | incidence of hemosiderosis in liver vs controls | Female | Adult | 8/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EPN | decreased @ 12, 36, 108 ug/g | embryo weight and length, % normal survivors versus controls | Not Reported | Embryo | 12/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory | |
EPN | decreased @ 12, 36 ug/g | brain weight, protein content, acetylcholinesterase and neurotoxic esterase versus controls | Not Reported | Hatchling | 12/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory | |
EPN | decreased @ 12 ug/g (48%), 36 ug/g (29%), 108 ug/g (0%) | % surviving to hatch versus controls | Not Reported | Hatchling | 12/group | Toxicity Factor Datasets | 72 hr of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | lead only: 1.02 (+/- 0.22); lead-iron: 0.75 (+/- 0.10) ppm, wet wt | lead concentration in kidneys (mean +/- SE) | Male | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
LEAD (elemental) | lead only: 1.15 (+/- 0.29); lead-iron: 0.32 (+/- 0.05) ppm, wet wt | lead concentration in liver (mean +/- SE) | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD NITRATE | increased @ 25 ppm/3wks | accumulation in livers and kidneys versus controls | Male | Adult | 20/dose; 5/dose x time group | Toxicity Factor Datasets | 1 yr | Laboratory | |
LEAD NITRATE | increased @ 5 ppm diet (66 +/-13 ppm blood) and @ 25 ppm diet (154 +/-28 ppm blood) | lead concentration in blood after 12 weeks exposure (mean +/- SE) versus controls | Male | Adult | 20/dose; 5/dose x time group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
MERCURY COMPOUNDS | 2.5 (carcass); 1.25 (egg); 23.7 (kidney) ppm, wet wt | mercury residues in whole carcass, egg contents, and kidneys | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
LEAD COMPOUNDS | 3.7 (carcass); 2.5 (egg); 2.5 (eggshells); 9.6 (bone) ppm, wet wt @ 100 ppm lead; 3.4 (carcass); 0.88 (egg); 2.8 (eggshells); 35.0 (bone) ppm, wet wt @ 100 ppm lead + DDE |
lead residues in whole carcass, egg contents, eggshells, and bone | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM, SELENOMETHIONINE | increased (40%) @ 60 ppm Se | incidence of mortality versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | 1 d | Laboratory | |
ARSENATE, SODIUM, SELENOMETHIONINE | increased @ 60 ppm Se | incidence of ducklings with histopathological lesions versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ALUMINUM SULFATE | decreased @ 1000 (LL) | food consumption versus controls | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | decreased @ 1200 pmm (30 d of age) | weight:length of humerus | Male | Juvenile | 36 birds/dose | Toxicity Factor Datasets | 14 d | Laboratory | |
NICKEL SULFATE | decreased @ all doses (by 60 d of age) | weight:length of humerus | Female | Juvenile | 36 birds/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | increased @ 0.5, 3 ppm | changes in approach behavior (maternal call stimulus) | Not Reported | Juvenile | 249 (control); 276 (0.5 ppm); 108 (3 ppm) | Toxicity Factor Datasets | Laboratory | |
METHYLMERCURY DICYANDIAMIDE | increased @ 0.5, 3 ppm | changes in avoidance behavior (frightening stimulus) | Not Reported | Juvenile | 319 (control); 339 (0.5 ppm); 158 (3 ppm) | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | 13-20 ppm, wet wt | mean Se concentration in eggs | Female | Adult | 5 birds | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM | increased to 0.4 (@ 0 ppm), 5.0 (@ 10 ppm), 3.2 (@ 20 ppm), 2.8 (@ 40 ppm) ppm, wet wt | Se concentrations in livers after 6 wks of treatment versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
SELENOMETHIONINE | increased @ 40 ppm (25%) | mortality compared to controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | increased @ 20 ppm | serum glutamic pyruvic transaminase activity by 8 wks of treatment compared to controls | Not Reported | Juvenile | 12 birds per timexdose treatment | day old | Toxicity Factor Datasets | Laboratory |
CADMIUM CHLORIDE | 0.10 (@ 0 ppm), 10.13 (@ 5 ppm), 16.25 (@ 10 ppm), 42.21 (@ 20 ppm) ppm, wet wt | mean Cd concentrations in liver by 12 wks of treatment | Not Reported | Juvenile | 12 birds per timexdose treatment | day old | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | decreased @ 1000 ppm B | hematocrits and hemoglobin concentrations versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory | |
BORIC ACID, SELENOMETHIONINE | decreased @ 15 ppm Se (with or w/out B), and 1000 ppm B | hematocrits and hemoglobin concentrations versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | no effect | % survival versus controls | Not Reported | Juvenile | 15/group | Toxicity Factor Datasets | 1-day old | Laboratory | |
SELENOMETHIONINE | increased @ 15 ppm, 60 ppm (adequate protein, no methionine added) | incidence of histopathological changes in livers versus controls | Not Reported | Juvenile | 15/group | Toxicity Factor Datasets | 1-day old | Laboratory | |
SELENOMETHIONINE | 11.6 (@15 ppm diet), 48.6 (@ 60 ppm diet) ppm, wet wt | geometric mean Se concentration in liver (adequate protein in diet) | Not Reported | Juvenile | 15/group | Toxicity Factor Datasets | 1-day old | Laboratory | |
SELENOMETHIONINE | decreased @ 60 ppm (regardless of methionine suppl. or protein levels) | body, liver and spleen weights, and tarsus length versus controls | Not Reported | Juvenile | 15/group | Toxicity Factor Datasets | 1-day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | body weight or plasma electrolyte levels | Both Male and Female | Juvenile | 4 | Toxicity Factor Datasets | 3-5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease @ 0.5, 1, 3% | plasma corticosterone concentration, compared to control | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 18 wks | Laboratory | |
CRUDE OILS | decrease @ 0.5% | plasma corticosterone concentration, compared to control | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 18 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
BORIC ACID | Liver; 3 ug/g @ 30 ppm, 17 ug/g @ 300 ppm, 51 ug/g @ 1000 ppm: Brain; 4 ug/g @ 30 ppm, 19 ug/g @ 300 ppm, 66 ug/g @ 1000 ppm | boron concentrations in ducklings 21 d of age (geometric mean; ug/g dry weight). Concentrations at other doses were not detected. | Both Male and Female | Juvenile | 10-13/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FUEL OILS | decrease @ 5, 10, 20, 50 ul | 30-d % hatching success | Not Reported | Embryo | 50/dose | Toxicity Factor Datasets | 8d of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
TRIMETHYLTIN CHLORIDE | increase @ 5 ppm | cephalic tumor incidence | Not Reported | Juvenile | 5/dose | Toxicity Factor Datasets | 3-4 d | Laboratory | |
TRIETHYLTIN CHLORIDE | no effect | % mortality, compared to controls | Not Reported | Juvenile | 5/dose | Toxicity Factor Datasets | 3-4 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, OXYCHLORDANE, POLYCHLORINATED BIPHENYLS | positive correlation | relationships between EROD activity and dieldrin concentrations | Female | Adult | 5 birds/timepoint (timepoints = 0,10,20,32,42,52,59,70,80,90,100 days) | Bloomington | Toxicity Factor Datasets |
DDE (4,4'-), DIELDRIN, OXYCHLORDANE, POLYCHLORINATED BIPHENYLS | positive correlation | relationship between BROD, PROD, and EROD activities and total PCB, oxychlordane, and TEQs concentrations | Female | Adult | 5 birds/timepoint (timepoints = 0,10,20,32,42,52,59,70,80,90,100 days) | Bloomington | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EMAMECTIN BENZOATE | no effect | incidence of signs of toxicity and body weight versus controls | Both Male and Female | Adult | 16 pairs/group | Toxicity Factor Datasets | 22 weeks | Laboratory | |
EMAMECTIN BENZOATE | no effect | feed consumption versus controls | Both Male and Female | Adult | 16 pairs/group | Toxicity Factor Datasets | 22 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ALUMINUM SULFATE, SULFURIC ACID | reduced @ 0.5% Al or 0.277 mol sulfate/kg | growth of tibia versus ad libidum controls | Both Male and Female | Juvenile | 8 birds/treatment | Toxicity Factor Datasets | 3 d | Laboratory | |
ALUMINUM SULFATE, SULFURIC ACID | reduced @ 0.5% Al | tibial dry weight, and ash and calcium content versus ad libidum controls | Both Male and Female | Juvenile | 8 birds/treatment | Toxicity Factor Datasets | 3 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | 4.6 (0.18) ppm B @ 450 ppm B; 8.5 (0.34) ppm B @ 900 ppm B; 3.7 (0.16) ppm Se @ 3.5 ppm Se; 6.2 (0.27) ppm Se @ 7 ppm | mean (SE) wet wt concentrations of B and Se in liver | Both Male and Female | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory | |
BORIC ACID, SELENOMETHIONINE | 6.5 (0.25) ppm B @ 450 ppm B; 11 (0.4) ppm B @ 900 ppm B; 3.5 (0.10) ppm Se @ 3.5 ppm Se; 7.1 (0.28) ppm Se @ 7 ppm | mean (SE) wet wt concentrations of B and Se in egg | Both Male and Female | Both Adults and Juveniles | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | reduced @ 869 ug/g, corn diet | body weight compared to corn diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory | |
LEAD COMPOUNDS | reduced @ 869 ug/g, corn diet | hemoglobin concentration versus corn diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | increased for lead shot, steel and tungsten-iron groups | iron concentrations in femur and liver versus controls | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory | |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | increased for lead, steel shot | renal concentrations of iron versus controls | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory | |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 10.3(0.7) ppm in femur, 14.1(0.6) ppm in liver, 6.8(0.2) in kidneys | mean(SE) dry wt tungsten concentrations in tissues of tungsten-iron-dosed birds | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | decreased @ 10 ppm Se, 10 ppm Hg, 10 ppm Hg + 10 ppm Se | plasma phosphorus concentrations versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory | |
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | decreased @ 10 ppm Hg | glutathione peroxidase activity (plasma and liver) and glucose-6-phosphate dehydrogenase (liver and brain) versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | decreased with Pb | liver weight versus controls (females only) | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no effect with Fe or Bi | onset of lay and time to lay 21 eggs versus controls | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CYANOFENPHOS | increased @ 2.0, or 4.0 mg cyanofen/kg/d, 10 mg leptophos/kg/d. | incidence of histological lesions in axons and myelin sheaths | Both Male and Female | Juvenile | 10 | laboratory | Toxicity Factor Datasets | 1 week | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ALDICARB | 1.92 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hours | Laboratory | |
ALDICARB | 3.60 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 7 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | decreased @ all doses | % drake encounter scores | Male | Both Adults and Juveniles | 30 per group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | kidney Zn concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | no effect | BW versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD ACETATE | increased | liver and kidney Pb concentrations versus controls | Male | Adult | 30 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | fertility, hatchability and duckling weight | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory | |
DDT (Technical Grade Mixture) | no effect | hepatic microsomal enzyme activity (aniline hydroxylase and aminopyrine N-demethylase) | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory | |
DIELDRIN | 0.3 ug/g dry wt. @ 0 ppm; 0.9 - 5.0 @ 1 ppm; 4.1 - 40.1 @ 5ppm; 6.1 - 78.5 @ 10 ppm | dieldrin concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | increase @ 15, 30 ppm | plasma and liver GSH-peroxidase activity (for all Se forms), compared to controls | Not Reported | Juvenile | 10/dose | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1242 | 8.9% decrease @ 150 ppm | eggshell thickness, compared to control | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1242 | 105.0 (7.7 SE) mg Aroclor 1260/kg egg @ 150 ppm | PCB concentration in eggs (PCB resembled Aroclor 1260 profile most closely) | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DICOFOL | no effect | body weight at end of study | Female | Adult | 4-8/dose | Toxicity Factor Datasets | Laboratory | |
DICOFOL | no effect | mean daily food consumption rate (169.8 g food/kg body weight) | Female | Adult | 4-8/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LINDANE | no effect | body weight at end of study | Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | increase @ 3 ppm | responsiveness of offspring to maternal call; % that approached call and % that spent 100% of time near call after initial approach | Female | Adult | 4 adults/dose; 148-156 offspring/dose | Toxicity Factor Datasets | 10 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | decreased | brain acetylcholinesterase activity compared to controls | Both Male and Female | Adult | 24 pairs/dose | Toxicity Factor Datasets | 7 and 11 months old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DICROTOPHOS | 63% | maximal brain acetylcholinesterase activity inhibition compared to control (4 hrs post-dose) | Not Reported | Juvenile | 4/group | Toxicity Factor Datasets | 1 day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
CARBOFURAN | increased @ 132 and 264 g/ha | occurrence of acute poisoning symptoms compared with controls | Not Reported | Juvenile | 29-38/group | Toxicity Factor Datasets | CANADA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
MALATHION | decreased @ 125 lb/acre | crown-rump length at day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 8 of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ACEPHATE | 11/36 | mortality incidence by 20 hrs post-dose | Not Reported | Juvenile | 36/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease | % fertile eggs and # of ducklings; when male, female or both male and female exposed to oil, compared to control | Female | Adult | 3 pairs/dose | Toxicity Factor Datasets | 5.5 mo at initiation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 17% decrease | eggshell thickness, compared to control | Female | Adult | 10 hens /dose; 8 eggs/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ALUMINUM SULFATE | see table | Ca, Al, P concentrations in femur for different treatments after 2 and 10 wks of treatment | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | decreased @ 30 ppm as Se-met or yeast, or 15 ppm as wheat | food consumption compared to controls | Not Reported | Juvenile | 25 birds/group | Toxicity Factor Datasets | 1 day | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | California Counties |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | ppm wet wt: 1.40 (0.7), blood; 6.40 (4.92), liver; 38.64 (19.18), femur @ 2 #four shot | mean (2SE) lead concentrations in liver, femur and blood | Male | Adult | 31 birds | Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 1.23 +/- 0.12 ug/g wet weight | mean +/- SE p,p'-DDE concentration in shell gland mucosa | Female | Adult | Not Reported | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CRUDE OILS | no effect | % mortality, compared to controls | Male | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease @ 1, 5, 10 ul | 18-d % survival, mean embryonic weight, crown-rump length (5ul) and bill length | Both Male and Female | Embryo | 50/dose | Toxicity Factor Datasets | 1d of development | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | decreased | incidence of delayed hypersensitivity reactions to antigen versus controls | Male | Adult | Controls = 24 Treated = 8 |
Laboratory | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | decreased | eggshell thickness versus controls | Female | Adult | 5 hens; 19 eggs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | one shot: 180.4 (18.1), female; 5.0 (0.6), male two shot: 183.4 (21.2), female; 15.9 (4.1), male |
mean (SE) lead residues in femur | Both Male and Female | Adult | 20 females, 10 males/group | Toxicity Factor Datasets | Laboratory |
Killdeer (Charadrius vociferus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
CARBARYL | increased at 0.56 kg/ha (2, 8-9 d. post-spray) | whole carcass concentration of carbaryl | Not Reported | Not Reported | 8-9 birds/group | Toxicity Factor Datasets | |
CARBARYL | no effect | whole carcass lipid content | Not Reported | Not Reported | 6-13 birds/group | Toxicity Factor Datasets |
California Brown Pelican (Pelecanus occidentalis ssp. californicus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | significantly decreased compared to pre-1943 samples | eggshell thickness (of intact or broken eggshells) | Female | Adult | 86 eggs | Anacapa Island and Isla Coronado Norte | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | increased compared to positive control (1969 data) | mean number of fledglings produced per nest in 1974 | Both Male and Female | Fledgling | 1286 nests | Anacapa Island and Isla Coronado Norte | Toxicity Factor Datasets |
Double-crested Cormorant (Phalacrocorax auritus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
POLYCHLORINATED BIPHENYLS | increased at 1606 ng/kg | hepatic EROD activity | Not Reported | Hatchling | 5-12 eggs/dose | Saskatchewan, British Columbia, Lake Ontario | Toxicity Factor Datasets | CANADA |
POLYCHLORINATED BIPHENYLS | positive regression | linear regression of hepatic EROD activity or cyt P450 content on Toxic Equivalency Factors | Not Reported | Hatchling | 5-12 eggs/dose | Saskatchewan, British Columbia, Lake Ontario | Toxicity Factor Datasets | CANADA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
POLYCHLORINATED BIPHENYLS | positive correlation | correlation of embryo mortality with TCDD equivalents in eggs | Not Reported | Embryo | 11 colonies @ 25-50 nests/colony | Great Lakes | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
POLYCHLORINATED DIBENZO-P-DIOXINS | increased | P-450-dependent arachidonic acid metabolism by liver microsomes | Not Reported | Embryo | 3 | Toxicity Factor Datasets | 1 day | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | increased @ all doses | hepatic EROD activity in treated embryos versus controls | Not Reported | Embryo | 83-86 eggs/treatment | Lake Winnipegosis, Manitoba | Toxicity Factor Datasets | Laboratory |
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | decreased @ 349 ug/kg egg | spleen weights in treated embryos versus controls | Not Reported | Embryo | 83-86 eggs/treatment | Lake Winnipegosis, Manitoba | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), POLYCHLORINATED BIPHENYLS | 28.8% decrease | mean thickness of eggshells collected in 1969 compared with pre-1946 museum specimens | Female | Adult | 17 eggs | Anacapa Island | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, HEXACHLOROBENZENE, MERCURY COMPOUNDS, POLYCHLORINATED BIPHENYLS | 95% | percent of eggs lost or broken before hatching in contaminated colonies | Not Reported | Embryo | 235 eggs | Lake Huron | Toxicity Factor Datasets |