Hepatic microsomal ethoxyresorufin O-deethylase-inducing potency in ovo and cytosolic Ah receptor binding affinity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: comparison of four avian species

Author(s)
Sanderson, J. Thomas and Gail D. Bellward
Year
Article Title
Hepatic microsomal ethoxyresorufin O-deethylase-inducing potency in ovo and cytosolic Ah receptor binding affinity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: comparison of four avian species
Volume
132
Pages
131-145
Start Page Number
131
Final Page
145
Review

Datapoints

Displaying 1 - 5 of 5 datapoints.
Species: Double-crested Cormorant (Phalacrocorax auritus)
Chemical Toxicity Endpoint Type Endpoint Description Endpoint Value Sample Size Life Cycle Stage Study Duration Type
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) TOX-REPRO - reproductive success mortality observed at 3, 10, 100 ug/kg 6-10 eggs/dose Hatchling NR Toxicity Factor Datasets
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) TOX-REPRO - development body and organ weights no effect 6-10 eggs/dose Hatchling NR Toxicity Factor Datasets
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) TOX-REPRO - development edema observed at 3, 10, 100 ug/kg 6-10 eggs/dose Hatchling NR Toxicity Factor Datasets
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) TOX-EXP IND - biomarkers hepatic microsomal cytP450 content increased at 10, 100 ug/kg 6-10 eggs/dose Hatchling NR Toxicity Factor Datasets
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) TOX-EXP IND - biomarkers hepatic microsomal EROD activity increased at 3, 10, 100 ug/kg 6-10 eggs/dose Hatchling NR Toxicity Factor Datasets

Comment

Please let us know if the information on this page is helpful for you. Enter your comment and leave your email address if you would like to receive a response. Thank you!
OEHHA is subject to the California Public Records Act and other laws that require the release of certain information upon request. If you provide comments, please be aware that your name, address and e-mail may be available to third parties. In addition, all public comments will be posted on our web site upon the close of the comment period.
OEHHA California Office of Environmental Health Hazard Assessment