Mallard duck (Anas platyrhynchos)
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD NITRATE | decreased @ 3,000, 30,000 ppm, incubation day 3 exposure | embyronic length and weight by incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | 3 or 8 days of incubation (time of treatment) | Laboratory | |
METHYLMERCURY CHLORIDE | decreased @ all doses | embryo length or weight by incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | 3 or 8 days of incubation (time of treatment) | Laboratory | |
METHYLMERCURY CHLORIDE | decreased @ 5,000 ppm, incub. day 3 exposure | embryo survival through day 18 of incubation and % of survivors that were normal versus controls | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | 3 or 8 days of incubation (time of treatment) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased in Pb/commerical (hemoglobin only), Pb/corn+Ca, and Pb/corn only | red blood cell counts, packed cell volume, hemoglobin concentration versus controls | Both Male and Female | Adult | treatment = 10/group control = 5 |
Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increased with Pb/corn + Ca, Pb/corn only | blood protoporphyrin concentrations versus controls | Both Male and Female | Adult | treatment = 10/group control = 5 |
Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE, LEAD CHLORIDE | 7.2 (0.9) ug Pb/g @ 100 ppm Pb; 104.8 (19.1) ug Pb/g @ 100 ppm Cd; 54.2 (3.7) ug Cd/g @ 50 ppm Cd + 50 ppm Pb (dry wt) | mean (SE) concentrations in liver | Male | Juvenile | 6-8 birds/dose | Toxicity Factor Datasets | 128 d (at initiation) | Laboratory | |
CADMIUM CHLORIDE, LEAD CHLORIDE | 67.8 (12.4) @ 10 ppm Cd; 371.8 (22.3) @ 100 ppm Cd; 3.4 (0.6) @ 100 ppm Pb; 201.0 (26.9) @ 50 ppm Cd + 50 ppm Pb (ug/g, dry wt) | mean (SE) Cd concentrations in kidney | Male | Juvenile | 6-8 birds/dose | Toxicity Factor Datasets | 128 d (at initiation) | Laboratory | |
CADMIUM CHLORIDE, LEAD CHLORIDE | 4.1 (0.5) @ 10 ppm Pb; 22.5 (1.5) @ 100 ppm Pb; 3.1 (0.3) @ 5 ppm Cd + 5 ppm Pb; 16.1 (1.4) @ 50 ppm Cd+ 50 ppm Pb (ug/g, dry wt) | mean (SE) Pb concentrations in kidney | Male | Juvenile | 6-8 birds/dose | Toxicity Factor Datasets | 128 d (at initiation) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM | no effect | survival rate versus controls | Both Male and Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory | |
ARSENATE, SODIUM | decreased @ 30, 100, 300 ppm | growth rate versus controls | Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory | |
ARSENATE, SODIUM | decreased @ 300 ppm | growth rate versus controls | Male | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
STEEL COMPOUNDS, TRIBUTYLTIN | increased in both groups (no treatment diffs) | white blood cell counts, monocyte counts, total protein concentrations over study period | Both Male and Female | Juvenile | 20/group | Toxicity Factor Datasets | 7 wks | Laboratory | |
STEEL COMPOUNDS, TRIBUTYLTIN | increased with steel shot, wk 8 | overall response score (inflammation, muscle damage changes) | Both Male and Female | Juvenile | 20/group | Toxicity Factor Datasets | 7 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | no effect | body wt, hematocrit, hemoglobin, food consumption versus controls | Both Male and Female | Adult | 20 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory | |
CADMIUM CHLORIDE | 2.116 (@ 2 ppm), 19.510 (@ 20 ppm), 96.600 9@ 200 ppm) ppm, wet wt | mean Cd concentrations in liver after 90 d of treatment | Both Male and Female | Adult | 20 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | decreased @ 3 ppm | hatching success and 1 wk survival of hatchlings compared to controls | Not Reported | Juvenile | 10 females, 3 males/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | decreased @ 30 ppm (as Se-met or yeast) | food consumption compared to controls | Not Reported | Juvenile | 25 birds/group | Toxicity Factor Datasets | 1 day | Laboratory | |
SELENIUM COMPOUNDS, SELENOMETHIONINE | decreased @ 30 ppm (as Se-met or yeast) | body weights compared to controls | Not Reported | Juvenile | 25 birds/group | Toxicity Factor Datasets | 1 day | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM, SELENOMETHIONINE | increased @ 10,25 ppm (as selenite), 10 ppm (as selenomethionine) | number of embryos showing malformations or embryotoxicity compared to controls | Not Reported | Embryo | 5-11 pairs/group | Toxicity Factor Datasets | Laboratory | |
SELENOMETHIONINE | increased @ 8, 16 ppm | incidence of malformed embyros compared to controls | Not Reported | Embryo | 5-11 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | decreased @ 32 ppm | body weight, liver DNA:RNA ratio, hematocrit compared to controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory | |
SELENOMETHIONINE | decreased @ 16, 32 ppm | hemoglobin concentration compared to controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PROPOXUR | 7.38 (5.97-9.14), 12.7 (10.2-15.9), 14.6 (12.4-17.4), 9.58 (7.61-12.1) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hr, 7 d, 30 d, or 6 mos | Laboratory | |
ALDICARB | 4.44 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 6 mos | Laboratory | |
DICROTOPHOS | 6.17 (3.33-11.4), 7.03 (5.30-9.31), 6.73 (5.53-8.19), 4.14 (3.33-5.16) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hr, 7 d, 30 d, or 6 mos | Laboratory | |
PARATHION | 1.65 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hours | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | increased in 2nd generation | food consumption versus controls | Both Male and Female | Adult | 14 pairs/group | Toxicity Factor Datasets | Laboratory | |
METHYLMERCURY DICYANDIAMIDE | decreased in 3rd generation | eggshell thickness versus controls | Female | Adult | 14 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PENTACHLOROPHENOL | no effect @ 423.2 ug/g | total body weight, compared to control; reported as the NOAEL for the study | Not Reported | Juvenile | 6/dose | Toxicity Factor Datasets | 4 d | Laboratory | |
PENTACHLOROPHENOL | 22.2 +/- 5.5 ug/g lipid, 30.7 +/- 10.3 ug/g liver, 11.0 +/- 0 ug/g muscle, 4.0 +/- 1.4 ug/g brain at 961 ug/g diet | mean +/- SD tissue concentrations at the reported LOAEL (development) | Not Reported | Juvenile | 4-6 | Toxicity Factor Datasets | 4 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 18% decrease @ 40 mg/kg | eggshell index (shell weight/length x breadth), compared to control | Female | Adult | 18 | Toxicity Factor Datasets | 1 yr | Laboratory | |
DDE (4,4'-) | 38 ug/g wet weight egg (yolk + white), 1.20 ug/g wet weight egg shell gland mucosa @ 40 mg/kg | mean DDE concentrations | Female | Adult | 7-9 | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID | increase @ 100, 400, 1600 ppm | plasma triglyceride concentration (21-42% increase, compared to controls) | Both Male and Female | Juvenile | 10 animals/pen; 3 pens/dose | Toxicity Factor Datasets | 1 d | Laboratory | |
BORIC ACID | increase @ 1600 ppm | plasma calcium concentration (6-10% greater than controls) and brain acetylcholinestrase activity (umol/min/g) | Both Male and Female | Juvenile | 10 animals/pen; 3 pens/dose | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
COREXIT 9527 | no effect | % mortality, compared to controls | Male | Adult | 6/dose | Toxicity Factor Datasets | Laboratory | |
COREXIT 9527 | no effect | body weight, compared to controls | Male | Adult | 6/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | onset of laying, egg production, egg fertility and egg hatchability, compared to controls | Female | Adult | 20 hens/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PHOSPHORUS (YELLOW OR WHITE) | 6.46 mg/kg bw (5.19-7.69 95% CI) | 24 hour median lethal dose | Male | Adult | 4-5 birds/dose | Toxicity Factor Datasets | Laboratory | |
PHOSPHORUS (YELLOW OR WHITE) | 3.90 mg/kg bw (3.24-4.69 95% CI) | 24 hour median lethal dose | Female | Adult | 4-5 birds/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | increased @ 20,100, 250, 500 mg/kg bw | hepatic microsomal EROD and PROD activities versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory | |
AROCLOR 1254 | decreased @ 20, 100, 250, 500 mg/kg bw | plasma triiodothyronine concentrations versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EMAMECTIN BENZOATE | 76 mg/kg bw, 56-102 (95% CI) | acute oral LD50 | Both Male and Female | Adult | 10/dose | Toxicity Factor Datasets | 19 weeks | Laboratory | |
EMAMECTIN BENZOATE | < 25 mg/kg bw | no-observed-effect level, based on body weight loss | Both Male and Female | Adult | 10/dose | Toxicity Factor Datasets | 19 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | decreased @ 900 ppm B | liver weight versus 450 ppm B group | Male | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory | |
BORIC ACID, SELENOMETHIONINE | reduced @ 900 ppm B | hemoglobin concentrations versus controls | Male | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | reduced @ 828 ug/g | hemoglobin concentrations versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | reduced @ 869 and 954 ug/g | delta aminolevulinic acid dehydratase activity versus corn or complete diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory | |
LEAD COMPOUNDS | reduced @ all doses | delta aminolevulinic acid dehydratase activity versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | increased @ 869 ug/g, corn diet | mortality versus corn diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with selenized yeast | body weight of 6 day old ducklings versus controls | Both Male and Female | Both Adults and Juveniles | 15 pairs/treatment group, 10 pairs/control group | Toxicity Factor Datasets | Laboratory | |
SELENIUM COMPOUNDS, SELENOMETHIONINE | increased with seleno-D,L-methionine, seleno-L-methionine, or selenized yeast | incidence of embryo deformities versus controls | Both Male and Female | Both Adults and Juveniles | 15 pairs/treatment group, 10 pairs/control group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | increased @ 10 ppm Hg | oxidized glutathione (GSSG) level versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory | |
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | reduced @ 10 ppm Hg, 10 ppm Hg + 10 ppm Se | protein-bound sulfhydryl in liver versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | increased with Bi | weight of eggs that did not hatch versus controls | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | decreased with Bi | weight of hatchlings versus controls | Both Male and Female | Juvenile | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM, SELENOMETHIONINE | increased @ 3.5 mg/L (selenite) or 2.2 mg/L (selenomethionine) | serum ALT enzyme activity versus controls n high selenite and selenomethionine groups. | Male | Adult | Controls = 24 Treated = 8 |
laboratory | Toxicity Factor Datasets | Laboratory |
SELENOMETHIONINE | increased (12-fold) | selenium concentrations in pectoral muscle | Male | Adult | Controls = 24 Treated = 8 |
Laboratory | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | no effect | distance run in 2 seconds from a fright stimulus vs controls | Not Reported | Chick | 32, 14, 14, 14, 11 in the 0, 1, 2, 4, and 8 ppm groups | Toxicity Factor Datasets | 6 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | decreased | eggshell quality (R-value) versus controls | Female | Adult | 5 hens; 19 eggs | Toxicity Factor Datasets | Laboratory | |
DDT (4,4'-) | no effect | calcium concentration in eggshell versus controls | Female | Adult | 5 hens; 19 eggs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | no effect | plasma glucose, NEFA, urea, or uric acid versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | liver cadmium concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | no effect | thyroid hormone concentrations versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | no effect | liver Cu concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | DDT <0.1, DDE 0.2 - 1.2 ug/g dry wt @ 0 ppm; DDT 0.6 - 2.4, DDE 1.2 - 10.1 @ 2 ppm; DDT 2.2 - 29.2, DDE 15.7 - 153.5 @ 20 ppm; DDT 14.9 - 102.0, DDE 45.0 - 187.0 @ 200 ppm | DDT and DDE concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean hematocrit values compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | 130(10.1) ppm in kidneys, 0.19(0.06) ppm in liver | mean(SE) wet wt concentration of bismuth in organs | Both Male and Female | Adult | 5 males, 5 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 706 - 1,995 | steady state bioconcentration factor for lipid, calculated on a wet weight basis; range for 7 doses | Not Reported | Juvenile | 8-16/dose | Toxicity Factor Datasets | 1 d at initiation | Laboratory | |
DIELDRIN | 178 - 684 | steady state bioconcentration factor for skin, calculated on a wet weight basis; range for 7 doses | Not Reported | Juvenile | 8-16/dose | Toxicity Factor Datasets | 1 d at initiation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | egg production during study period | Female | Adult | 5-10/dose | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | no effect | body weight at end of study | Female | Adult | 5-10/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | 6% decrease @ 10 ppm | eggshell thickness | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
TRICHLOROPHENOXYACETIC ACID (2,4,5-) | 106 lbs AI/acre (slope = 3.7) for exposure of 3d embryo; 116 lbs AI/acre (slope = 3.8) for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | Toxicity Factor Datasets | 3 or 8d of development | Laboratory | |
LINDANE | 8.5 lbs AI/acre (slope = 1.34) for exposure of 3d embryo; 7.3 lbs AI/acre (slope = 2.72) for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | Toxicity Factor Datasets | 3 or 8d of development | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
FENTHION | 100% @ 5 mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory | |
FENTHION | 16.9% @ 5mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | decreased @ all doses | food consumption compared with controls | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory | |
CHLORPYRIFOS | decreased @ all doses | body weight compared with controls | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLPARATHION | decreased if treatment initiated during egg laying | proportion of hens laying and number of eggs laid per hen compared to controls | Female | Adult | 12 pairs /group | Toxicity Factor Datasets | 7 mo | Laboratory | |
METHYLPARATHION | 2/12 when treatment initiated during early incub.; 2/11 when treatment initiated during late incub. | incidence of adult mortality during incubation compared with controls | Female | Adult | 12 pairs/group | Toxicity Factor Datasets | 7 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIAZINON | decreased @ 15 (aqueous), 2.0 (oil) lb/acre | embryo weight by day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
MALATHION | decreased @ 125 (aqueous), 14.0 (oil) lb/acre | embryo weight by day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory |
Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|
see citation tables | incidence of reduced growth and abnormal survivors for 42 compounds | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | incubation day 3-8 | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIISOPROPYL METHYLPHOSPHONATE | decrease | mean blood pressure, compared to baseline prior to exposure | Both Male and Female | Adult | 12 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
VANADYL SULFATE | no effect | body weight and food consumption compared among groups | Both Male and Female | Adult | 5 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory | |
VANADYL SULFATE | increased @ 100 ppm (maximum = 106 +/- 19 ppb, wet wt) | vanadium concentration in blood (sampled at 3 wk intervals) | Both Male and Female | Adult | 5 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase @ 5% | incidence of degeneration of kidney tubules | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | no effect | body weight versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increased @ 1 #four shot | mortality rate by 15 d post-dose versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CYANIDE | no effect | rhodanese and 3-mercaptopyruvate sulfurtransferase activities in liver and heart versus controls | Female | Adult | 5/treatment | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | decreased @ 3 ppm | duckling survival | Not Reported | Juvenile | Not Reported | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
POLYCYCLIC AROMATIC HYDROCARBONS (PAHs) | increase @ 0.2, 2.0 mg/kg egg | embryonic mortality, compared to controls | Not Reported | Embryo | 22/dose | Toxicity Factor Datasets | 5 d of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decreased | % normal hatchlings versus controls | Not Reported | Embryo | 492-518, 232-384, and 128-276 for the 0, 10, and 40 ppm DDE groups | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
TRIETHYLTIN CHLORIDE | decrease @ 50 ppm | body weight, compared to control | Not Reported | Juvenile | 5/dose | Toxicity Factor Datasets | 3-4 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | increase @ 10-20 ug/g | estradiol metabolism and cytochrome P450 concentration | Female | Adult | 4/dose/sampling time | Toxicity Factor Datasets | 90 d at initiation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EPN | decreased @ 90, 270 ppm | food consumption and body weight compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), DDT (4,4'-) | see citation | figure of eggshell thickness over 30 d period (significant differences noted at various times) | Female | Adult | 20/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased | body weight and delta-aminolevulinic acid dehydratase activity versus controls | Male | Adult | 20/treatment group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CYANIDE | increased @ 1, 2 mg/kg bw | serum creatine kinase activity versus controls | Female | Adult | at least 5 determinations/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decreased @ 500, 1000, 5000 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | Toxicity Factor Datasets | Laboratory |