Mallard duck (Anas platyrhynchos)
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254, DDE (4,4'-) | see citation | figure of # eggs/female/wk over time | Female | Adult | 10/dose | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 373 (95% CL; 152-574) ppm lipid basis @ 40 ppm diet | DDE residue concentrations in eggs | Female | Adult | 12 | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1254, DDE (4,4'-) | 344 (95% CL; 156-686) ppm DDE lipid basis and 346 (95%CL; 133-686) ppm PCB lipid basis @ 40 ppm DDE + 40 ppm PCB diet | mean DDE and PCB residue levels in eggs | Female | Adult | 13 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease @ 2.5 - 5% | hematocrit, compared to control | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory | |
CRUDE OILS | increase @ 0.25 - 5.0% | plasma alanine aminotransferase activity, from liver | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory | |
CRUDE OILS | increase @ 0.025 - 5% | pathological release of ornithine carbamyltransferase from kidney | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
IRON (elemental), LEAD (elemental) | no effect | serum enzyme levels versus controls (at 30 or 60 d post dose) | Male | Adult | 2/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CYANIDE | decreased @ all doses | ATP levels in liver and brain tissues versus controls | Female | Adult | 5/treatment | Toxicity Factor Datasets | Laboratory | |
CYANIDE | no effect | ATP levels in heart versus controls | Female | Adult | 5/treatment | Toxicity Factor Datasets | Laboratory | |
CYANIDE | increased | rhodanese and 3-mercaptopyruvate sulfurtransferase activities in brain versus controls | Female | Adult | 5/treatment | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased with increasing lead in bone | number of eggs laid | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
LEAD (elemental) | increased with lead shot (egg contents: 0.50 +/-0.06; egg shell: 2.80 +/-0.25 ppm, wet wt) and lead-iron shot (egg shell: 1.42 +/-0.26 ppm, wet wt) | lead in egg contents and shell (mean +/- SE) versus controls | Female | Adult | control=10 eggs; treatment=20 eggs | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased in all groups dosed with lead shot | incidence of clinical signs, weight loss, breast muscle atrophy | Both Male and Female | Adult | treatment = 10/group control = 5 |
Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increased with Pb/corn+Ca (50%), and Pb/corn only (100%) | % mortality versus controls | Both Male and Female | Adult | treatment = 10/group control = 5 |
Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | 1.367 (<0.05-29.80) | geometric mean concentration in kidneys (range) | Not Reported | Not Reported | 39 birds | Ebro Delta Natural Park | Toxicity Factor Datasets | ITALY |
LEAD COMPOUNDS | humerus, 41.652 (8.20-211.6); spleen, 0.669 (0.128-2.397); pancreas, 3.295 (1.074-13.47); brain, 1.367 (0.120-117.1) | geometric mean concentrations (ranges) in humerus, spleen, pancreas, and brain | Not Reported | Not Reported | 6-10 birds/tissue type | Ebro Delta Natural Park | Toxicity Factor Datasets | ITALY |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM, SELENOMETHIONINE | increased @ 60 ppm Se | glutathione peroxidase activity versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | 1 d | Laboratory | |
ARSENATE, SODIUM, SELENOMETHIONINE | increased (100%) @ 60 ppm Se and (53%) @ 200 ppm As | incidence of mortality versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ALUMINUM SULFATE | decreased with LL and LH diets | femur breaking strength (LL,LH vs. NN diets) after 10 wks of treatment | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | Laboratory | |
ALUMINUM SULFATE | increased in LL diets | incidence of clinical signs (LL vs. LH vs. NN diets) | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | 1.0-22.7 (liver), 2.7-74.4 (kidney) ppm, wet wt | Ni concentrations (ranges) in liver and kidney in ducklings that died @ 1200 ppm | Both Male and Female | Juvenile | 36 birds/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | 1 (@ 0.5 ppm), 6.46-9.19 (@ 3 ppm) ppm in eggs | mercury concentrations in eggs (at plateau) | Female | Adult | 10 females, 3 males/dose | Toxicity Factor Datasets | Laboratory | |
METHYLMERCURY DICYANDIAMIDE | decreased @ 0.5, 3 ppm | duration of egg production compared to controls | Female | Adult | 10 females, 3 males/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | decreased @ 30 ppm as Se-L-met | survival rate compared to controls | Not Reported | Juvenile | 25 birds/group | Toxicity Factor Datasets | 1 day | Laboratory | |
SELENIUM COMPOUNDS, SELENOMETHIONINE | 11-12 (@ 15 ppm as Se-met or wheat), 6.2 (@ 15 ppm as yeast), 19-20 (@ 30 ppm as Se-met or wheat), 9.9 (@ 30 ppm as yeast) ppm, wet wt | mean concentrations of Se in livers | Not Reported | Juvenile | 25 birds/group | Toxicity Factor Datasets | 1 day | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM, SELENOMETHIONINE | decreased @ 25 ppm (selenite), 10 ppm (selenomethionine) | hatchability compared to controls | Not Reported | Juvenile | 5-11 pairs/group | Toxicity Factor Datasets | Laboratory | |
SELENOMETHIONINE | decreased @ 8, 16 ppm | hatchability compared to controls | Not Reported | Juvenile | 5-11 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased @ 32 ppm | incidence of liver histopathological lesions, liver:body wt ratios versus controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory | |
SELENOMETHIONINE | increased @ 32 ppm | plasma alkaline phosphatase activity and total protein levels versus controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | 22.5 (@ 15 ppm Se w/out B), 41.9 (@ 15 ppm Se w/B) ppm Se, wet wt 13.0 (@ 1000 ppm B) ppm B, wet wt |
geometric mean Se and B concentrations in liver | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | ppm, wet wt: 0.79-0.86 (egg); 0.89-1.62 (liver); 1.52-1.82 (kidney); 9.03-11.17 (primary feathers); 0.67-0.83 (breast muscle); 0.44-0.59 (brain); 0.51-0.65 (ovary) | mean concentration of Hg in tissues (ranges are for 3 generations) | Female | Adult | 3-14 birds/tissue x generation group | Toxicity Factor Datasets | Laboratory | |
METHYLMERCURY DICYANDIAMIDE | no effect | body weight versus controls | Both Male and Female | Adult | 14 pairs/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CRUDE OILS | increased with light, moderate and heavy oiling | thermal conductance of feathers and body heat loss versus controls | Both Male and Female | Adult | 3 birds/treatment | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | plasma calcium concentration | Female | Adult | Not Reported | Toxicity Factor Datasets | 1 yr | Laboratory | |
DDE (4,4'-) | 25% decrease @ 40 mg/kg | calcium content of secreted fluid in the shell gland, compared to control | Female | Adult | 5/dose | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID | decrease @ 1600 ppm | growth rate measured as changes in body weight, compared to control | Both Male and Female | Juvenile | 10 animals/pen; 3 pens/dose | Toxicity Factor Datasets | 1 d | Laboratory | |
BORIC ACID | decrease @ 1600 ppm | hematocrit and hemoglobin concentration, compared to controls | Both Male and Female | Juvenile | 10 animals/pen; 3 pens/dose | Toxicity Factor Datasets | 1 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
FUEL OILS | no effect | body weight and gross lesion incidence, compared to controls | Male | Adult | 4-5/dose | Toxicity Factor Datasets | Laboratory | |
FUEL OILS | decrease @ 4.0, 7.0, 12.0 ml/kg/d | mean spleen index (spleen wt./body wt.) | Male | Adult | 4-5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CRUDE OILS | no effect | onset of laying, egg production, egg fertility, compared to controls | Female | Adult | 20 hens/dose | Toxicity Factor Datasets | Laboratory | |
CRUDE OILS | decrease | egg hatchability (# eggs hatching/# fertile eggs), compared to controls | Female | Adult | 20 hens/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, OXYCHLORDANE, POLYCHLORINATED BIPHENYLS | positive correlation | relationship between BROD, PROD, and EROD activities and total PCB, oxychlordane, and TEQs concentrations | Female | Adult | 5 birds/timepoint (timepoints = 0,10,20,32,42,52,59,70,80,90,100 days) | Bloomington | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
EMAMECTIN BENZOATE | no effect | feed consumption versus controls | Both Male and Female | Adult | 16 pairs/group | Toxicity Factor Datasets | 22 weeks | Laboratory | |
EMAMECTIN BENZOATE | no effect | microscopic changes to brain, spinal cord, or peripheral nerves versus controls | Both Male and Female | Adult | 16 pairs/group | Toxicity Factor Datasets | 22 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ALUMINUM SULFATE, SULFURIC ACID | reduced @ 0.5% Al | tibial dry weight, and ash and calcium content versus ad libidum controls | Both Male and Female | Juvenile | 8 birds/treatment | Toxicity Factor Datasets | 3 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | 6.5 (0.25) ppm B @ 450 ppm B; 11 (0.4) ppm B @ 900 ppm B; 3.5 (0.10) ppm Se @ 3.5 ppm Se; 7.1 (0.28) ppm Se @ 7 ppm | mean (SE) wet wt concentrations of B and Se in egg | Both Male and Female | Both Adults and Juveniles | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory | |
BORIC ACID, SELENOMETHIONINE | reduced @ 900 ppm B | body weight versus controls | Both Male and Female | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | reduced @ 869 ug/g, corn diet | hemoglobin concentration versus corn diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory | |
LEAD COMPOUNDS | no effect | body weight versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | increased @ 869 and 954 ug/g | protoporphyrin versus corn or complete diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | increased for lead, steel shot | renal concentrations of iron versus controls | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory | |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 250.6(39.0) ppm in femur, 78.3(9.7) ppm in liver, 256.3(22.2) in kidneys | mean(SE) dry wt lead concentrations in tissues of lead-dosed birds | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | decreased @ 10 ppm Hg | glutathione peroxidase activity (plasma and liver) and glucose-6-phosphate dehydrogenase (liver and brain) versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory | |
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | increased @ 10 ppm Se | hepatic GSSG reductase activity versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no effect with Fe or Bi | onset of lay and time to lay 21 eggs versus controls | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | increased with Fe | weight of eggs that hatched versus controls | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | decreased | incidence of delayed hypersensitivity reactions to antigen versus controls | Male | Adult | Controls = 24 Treated = 8 |
Laboratory | Toxicity Factor Datasets | Laboratory |
SELENITE, SODIUM, SELENOMETHIONINE | decreased | blood monocyte counts after 78 days exposure versus controls | Male | Adult | Controls = 24 Treated = 8 |
Laboratory | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | decreased @ 60 ppm (regardless of methionine suppl. or protein levels) | body, liver and spleen weights, and tarsus length versus controls | Not Reported | Juvenile | 15/group | Toxicity Factor Datasets | 1-day old | Laboratory | |
SELENOMETHIONINE | increased @ 15 (GSH-peroxidase only), 60 ppm Se, adequate protein | plasma GSH-peroxidase and alkaline phosphatase activities versus controls | Not Reported | Juvenile | 15/group | Toxicity Factor Datasets | 1-day old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ALDICARB | 3.60 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 7 days | Laboratory | |
MONOCROTOPHOS | 5.86 (4.70-7.29), 7.21 (5.79-8.98), 5.10 (4.44-5.86), 3.36 (2.77-4.09) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hr, 7 d, 30 d, or 6 mos | Laboratory | |
ALDICARB | 6.73 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 30 days | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | decreased | eggshell thickness versus controls | Female | Adult | 5 hens; 19 eggs | Toxicity Factor Datasets | Laboratory | |
DDT (4,4'-) | decreased | eggshell weight versus controls | Female | Adult | 5 hens; 19 eggs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | no effect | liver glycogen concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | no effect | % packed cell volume versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM, SELENOMETHIONINE | decreased | food consumption versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | Laboratory | |
SELENITE, SODIUM, SELENOMETHIONINE | decreased (liver decreased with selenite only) | bw and liver wt versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | hepatic microsomal enzyme activity (aniline hydroxylase and aminopyrine N-demethylase) | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory | |
DDT (Technical Grade Mixture) | DDT <0.1, DDE 0.2 - 1.2 ug/g dry wt @ 0 ppm; DDT 0.3 - 4.2, DDE 1.0 - 12.7 @ 2 ppm; DDT 1.3 - 25.0, DDE 5.0 - 110.1 @ 20 ppm; DDT 25.5 - 254, DDE 58.0 - 1234 @ 200 ppm | DDT and DDE concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean survival times compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean body weight and organ weights compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | body weight at end of experiment | Not Reported | Juvenile | 12/dose | Toxicity Factor Datasets | 1 d at initiation | Laboratory | |
DIELDRIN | no effect | no mortality observed | Not Reported | Juvenile | 12/dose | Toxicity Factor Datasets | 1 d at initiation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DICOFOL | 5.4 (0.3 SE) ug/g wet wt. @ 3 ug/g diet; 18.1 (1.2 SE) @ 10 ug/g diet; 37.1 (1.6 SE) @ 30 ug/g diet; 150.7 (9.9SE) @ 100 ug/g diet, | mean egg yolk concentrations of p,p'-dicofol after 37-42 d on dicofol diet | Female | Adult | 4-8/dose | Toxicity Factor Datasets | Laboratory | |
DICOFOL | ST = 1.020 - 0.056C | regression equation relating shell thickness (mm) to log10 yolk concentration (C, ug/g); r2=0.39 | Female | Adult | 100 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (Technical Grade Mixture) | increase @ 200 ppm | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory | ||
DDT (4,4'-) | decrease @ 20 - 200 ppm | eggshell thickness, weight and calcium concentration | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PARAQUAT | 1.5 lbs AI/acre (slope = 1.66) for exposure of 3d embryo; 2.5 lbs AI/acre (slope = 1.40) for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | Toxicity Factor Datasets | 3 or 8d of development | Laboratory | |
TOXAPHENE (POLYCHLORINATED CAMPHENES) | 108 lbs AI/acre (slope = 1.62) for exposure of 3d embryo; 101 lbs AI/acre (slope = 3.06) for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | Toxicity Factor Datasets | 3 or 8d of development | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PARATHION | 100% @ 5mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory | |
PARATHION | 0.8% @ 5 mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | 357 ppm | 11 day dietary LC50 | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory | |
CHLORPYRIFOS | 236 ppm | 11 day dietary LC10 | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
CARBOFURAN | no effect | growth rate to four weeks of age compared with controls | Not Reported | Juvenile | 8/group | Toxicity Factor Datasets | CANADA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIAZINON | 9.7 (day 3), 11.1 (day 8) lb/acre | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
PARATHION | 2.2 (day 3), 1.5 (day 8) lb/acre | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEPTOPHOS | 4/5 @ 260 ppm | incidence of CNS lesions | Both Male and Female | Juvenile | 3-5/group | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CRUDE OILS | 56% increase | hepatic cytochrome P450 content | Not Reported | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
CRUDE OILS | no effect | body weight | Not Reported | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased @ > 60 ug/dl blood | delta-aminolevulinic acid dehydratase activity | Both Male and Female | Not Reported | 21 birds | World Wildlife Fund Refuge, Tuscany | Toxicity Factor Datasets | ITALY |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | no effect | mortality versus controls | Both Male and Female | Adult | 20 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
PENTACHLOROPHENOL | decrease @ 961 ug/g | total body weight, compared to control; reported as the LOAEL for the study | Not Reported | Juvenile | 6/dose | Toxicity Factor Datasets | 4 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PHOSPHORUS (YELLOW OR WHITE) | 6.96 mg/kg bw (2.66-8.96 95% CI) | 24 hour median lethal dose | Female | Adult | 6 birds/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | increased @ 100, 250, 500 mg/kg bw | thyroid wt/body wt and liver wt/body wt ratios versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLPARATHION | no effect | number of eggs per incubated nest and percent fertility of eggs compared with controls | Both Male and Female | Adult | 12 pairs/group | Toxicity Factor Datasets | 7 mo | Laboratory |
Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|
see citation tables | LD50s for 42 compounds in aqueous and oil vehicles | Not Reported | Embryo | 30 eggs/group | Toxicity Factor Datasets | incubation day 3-8 | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased @ 7, 14, 21 d post-dose | concentration of lead in blood versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory |
Mallard duck (Anas platyrhynchos), Double-crested Cormorant (Phalacrocorax auritus)
Chemical | Endpoint Value | Endpoint Description | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|
POLYCHLORINATED BIPHENYLS | review | incidence of reproductive effects | Both Adults and Juveniles, Embryo | Not Reported | Toxicity Factor Datasets |