Male
Pacific Green Turtle (Chelonia mydas)
Chemical | Endpoint Value | Endpoint Description | Sex | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|
PCB | Range: <1.6-26 ng/g | Fat concentration | Male | 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
PCB | Range: <1.6 ng/g | Liver concentration | Male | 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
PCB | Range: <1.6-17.4 ng/g | Liver concentration | Male | 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | no effect | thyroid hormone concentrations versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | no effect | liver Cu concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | no effect | adrenal wt, corticosterone concentrations versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | no effect | liver Zn concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | kidney Cd concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | lead only: 1.02 (+/- 0.22); lead-iron: 0.75 (+/- 0.10) ppm, wet wt | lead concentration in kidneys (mean +/- SE) | Male | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
LEAD (elemental) | lead only: 0.58 (+/- 0.19); lead-iron: 0.25 (+/- 0.02) ppm, wet wt | lead concentration in liver (mean +/- SE) | Male | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
NICKEL SULFATE | decreased @ 1200 pmm (30 d of age) | weight:length of humerus | Male | Juvenile | 36 birds/dose | Toxicity Factor Datasets | 14 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease @ 0.5% | plasma corticosterone concentration, compared to control | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 18 wks | Laboratory | |
CRUDE OILS | increase @ 0.5, 1, 3% | hepatic microsomal naphthalene metabolism (nmol/min/mg protein) | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 18 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
PHOSPHORUS (YELLOW OR WHITE) | positive correlation | P4 concentration in fat versus dose | Male | Adult | 4-5 birds/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | reduced @ 900 ppm B | hemoglobin concentrations versus controls | Male | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | reduced @ 869 ug/g, corn diet | hemoglobin concentration versus corn diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory | |
LEAD COMPOUNDS | no effect | body weight versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | increased @ 869 and 954 ug/g | protoporphyrin versus corn or complete diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory | |
LEAD COMPOUNDS | reduced @ 828 ug/g | hemoglobin concentrations versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | reduced @ 869 and 954 ug/g | delta aminolevulinic acid dehydratase activity versus corn or complete diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory | |
LEAD COMPOUNDS | reduced @ all doses | delta aminolevulinic acid dehydratase activity versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | increased @ 869 ug/g, corn diet | mortality versus corn diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory | |
LEAD COMPOUNDS | increased @ 414, 828 ug/g | occurrence of intranuclear inclusion bodies in kidneys versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | increased @ 869 and 954 ug/g | incidence of renal tubular intranuclear inclusion bodies versus corn or complete diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory | |
LEAD COMPOUNDS | increased @ 828 ug/g | occurrence of lead poisoning signs versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | 4.1(1.03) ppm in blood, 13(1.2) ppm in liver @ 954 ug/g, complete diet; 4.0(0.58) ppm in blood, 38(6.5) ppm in liver @ 869 ug/g, corn diet | mean (SE) wet wt Pb concentrations in blood and liver | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory | |
LEAD COMPOUNDS | increased @ all doses | protoporphyrin levels in blood versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | 4.6(0.66) ppm @ 103 ug/g Pb; 9.3(0.82) ppm @ 207 ug/g Pb; 12(1.3) ppm @ 414 ug/g Pb; 28(4.6) ppm @ 828 ug/g Pb | mean(SE) wet wt concentrations of lead in liver | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
LEAD COMPOUNDS | no effect | body weight versus controls | Male | Adult | 10/ Pb treatment; 5/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 17.9(1.06) ppm @ 10 ppm Hg; 14.1(0.74) ppm @ 10 ppm Hg + 10 ppm Se | mean (SE) wet wt Hg concentrations in brain | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory | |
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | reduced @ 10 ppm Se, 10 ppm Se + 10 ppm Hg | hematocrit and hemoglobin values versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory | |
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | increased @ 10 ppm Hg + 10 ppm Se | plasma glucose concentrations versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 36-67% decrease @ 10-1000 ppm | salt gland excretion volume, compared to controls | Male | Not Reported | 12/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | decreased @ all doses/30 d post-treatment, and 200 ppm/90 d of treatment | mean testis weight versus controls | Male | Adult | 5 testes/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | increased @ 100, 250, 500 mg/kg bw | thyroid wt/body wt and liver wt/body wt ratios versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory | |
AROCLOR 1254 | increased @ 20,100, 250, 500 mg/kg bw | hepatic microsomal EROD and PROD activities versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory | |
AROCLOR 1254 | decreased @ 20, 100, 250, 500 mg/kg bw | plasma triiodothyronine concentrations versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory | |
AROCLOR 1254 | no effect | leukocyte counts, plasma biochemistry, corticosterone concentration versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory | |
AROCLOR 1254 | increased @ 250, 500 mg/kg bw | lymphocyte proliferation to PHA versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
ENDRIN | see citation | figures of carcass and blood endrin concentrations during elimination period (0-64d) | Male | Adult | 2-5/sample | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD NITRATE | decreased @ 25 ppm/3 wks, 5 ppm/12 wks | delta-aminolevulinic acid dehydratase activity in blood versus controls | Male | Adult | 20/dose; 5/dose x time group | Toxicity Factor Datasets | 1 yr | Laboratory | |
LEAD NITRATE | increased @ 25 ppm/3wks | accumulation in livers and kidneys versus controls | Male | Adult | 20/dose; 5/dose x time group | Toxicity Factor Datasets | 1 yr | Laboratory | |
LEAD NITRATE | increased @ 5 ppm diet (66 +/-13 ppm blood) and @ 25 ppm diet (154 +/-28 ppm blood) | lead concentration in blood after 12 weeks exposure (mean +/- SE) versus controls | Male | Adult | 20/dose; 5/dose x time group | Toxicity Factor Datasets | 1 yr | Laboratory | |
LEAD NITRATE | no effect | body weight and food consumption versus controls | Male | Adult | 20/group | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | see figure and table | figure and table showing decline of Hg in carcass, liver, and kidney over time | Male | Adult | 3-5 birds/group | Toxicity Factor Datasets | Laboratory | |
METHYLMERCURY DICYANDIAMIDE | 9.10 (whole body), 4.46 (carcass), 16.5 (liver), 17.6 (kidney) ppm, wet wt | mean Hg concentrations after 2 wk exposure | Male | Adult | 3-5 birds/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CRUDE OILS | no effect | % mortality, compared to controls | Male | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
CRUDE OILS | no effect | body weight, gross lesions or signs of clinical illness, compared to controls | Male | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
FUEL OILS | no effect | body weight and gross lesion incidence, compared to controls | Male | Adult | 4-5/dose | Toxicity Factor Datasets | Laboratory | |
FUEL OILS | decrease @ 4.0, 7.0, 12.0 ml/kg/d | mean spleen index (spleen wt./body wt.) | Male | Adult | 4-5/dose | Toxicity Factor Datasets | Laboratory | |
COREXIT 9527 | no effect | % mortality, compared to controls | Male | Adult | 6/dose | Toxicity Factor Datasets | Laboratory | |
COREXIT 9527 | no effect | body weight, compared to controls | Male | Adult | 6/dose | Toxicity Factor Datasets | Laboratory | |
FUEL OILS | increase @ 2.5, 4.0 ml/kg | susceptibility to Pasturella multocida estimated as % mortality 2-wks post-exposure to Pasturella multocida which was given on day 28 | Male | Adult | 9-32/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | decreased | incidence of delayed hypersensitivity reactions to antigen versus controls | Male | Adult | Controls = 24 Treated = 8 |
Laboratory | Toxicity Factor Datasets | Laboratory |
SELENITE, SODIUM, SELENOMETHIONINE | decreased | blood monocyte counts after 78 days exposure versus controls | Male | Adult | Controls = 24 Treated = 8 |
Laboratory | Toxicity Factor Datasets | Laboratory |
SELENITE, SODIUM, SELENOMETHIONINE | increased @ 3.5 mg/L (selenite) or 2.2 mg/L (selenomethionine) | serum ALT enzyme activity versus controls n high selenite and selenomethionine groups. | Male | Adult | Controls = 24 Treated = 8 |
laboratory | Toxicity Factor Datasets | Laboratory |
SELENOMETHIONINE | increased (12-fold) | selenium concentrations in pectoral muscle | Male | Adult | Controls = 24 Treated = 8 |
Laboratory | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased | body weight and delta-aminolevulinic acid dehydratase activity versus controls | Male | Adult | 20/treatment group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increased | erythrocyte protoporphyrin concentrations versus controls | Male | Adult | 20/treatment group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | no effect | body weight and hematocrit versus controls | Male | Juvenile | 20/treatment group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | 60% @ 2 shot, 30% @ 4 shot | cumulative mortality | Male | Adult | 10/treatment group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased @ 32 ppm | incidence of liver histopathological lesions, liver:body wt ratios versus controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory | |
SELENOMETHIONINE | increased @ 32 ppm | plasma alkaline phosphatase activity and total protein levels versus controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory | |
SELENOMETHIONINE | decreased @ 32 ppm | body weight, liver DNA:RNA ratio, hematocrit compared to controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory | |
SELENOMETHIONINE | decreased @ 16, 32 ppm | hemoglobin concentration compared to controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory | |
SELENOMETHIONINE | increased @ 2 ppm or greater | plasma glutathione peroxidase activity versus controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE, LEAD CHLORIDE | 7.2 (0.9) ug Pb/g @ 100 ppm Pb; 104.8 (19.1) ug Pb/g @ 100 ppm Cd; 54.2 (3.7) ug Cd/g @ 50 ppm Cd + 50 ppm Pb (dry wt) | mean (SE) concentrations in liver | Male | Juvenile | 6-8 birds/dose | Toxicity Factor Datasets | 128 d (at initiation) | Laboratory | |
CADMIUM CHLORIDE, LEAD CHLORIDE | 67.8 (12.4) @ 10 ppm Cd; 371.8 (22.3) @ 100 ppm Cd; 3.4 (0.6) @ 100 ppm Pb; 201.0 (26.9) @ 50 ppm Cd + 50 ppm Pb (ug/g, dry wt) | mean (SE) Cd concentrations in kidney | Male | Juvenile | 6-8 birds/dose | Toxicity Factor Datasets | 128 d (at initiation) | Laboratory | |
CADMIUM CHLORIDE, LEAD CHLORIDE | 4.1 (0.5) @ 10 ppm Pb; 22.5 (1.5) @ 100 ppm Pb; 3.1 (0.3) @ 5 ppm Cd + 5 ppm Pb; 16.1 (1.4) @ 50 ppm Cd+ 50 ppm Pb (ug/g, dry wt) | mean (SE) Pb concentrations in kidney | Male | Juvenile | 6-8 birds/dose | Toxicity Factor Datasets | 128 d (at initiation) | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | no effect | histological changes to nervous system, bones, feathers, feather follicles, claws and scaled skin versus controls | Male | Adult | 21/dose | Toxicity Factor Datasets | 14 mo | Laboratory | |
SELENOMETHIONINE | increased in birds that died, and in some 40 ppm survivors | histological changes to skin (loss of fat), muscle, liver, pancreas, kidney, lymph nodes, spleen, seminiferous tubules | Male | Adult | 21/dose | Toxicity Factor Datasets | 14 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | increased @ 10 ppm Hg | incidence of leg weakness versus controls | Male | Adult | 12/group | Toxicity Factor Datasets | 18 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased | hemoglobin and hematocrit versus controls | Male | Juvenile | 8 | Laboratory | Toxicity Factor Datasets | 6 months | Laboratory |
LEAD (elemental) | decreased (60%) | blood ALAD activity versus controls | Male | Juvenile | 8 | Laboratory | Toxicity Factor Datasets | 6 months | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | ppm wet wt: 3.47 (1.38), blood; 32.16 (11.60), liver; 114.78 (28.96), femur @ 2 #four shot | mean (2SE) lead concentration in liver, femur and blood | Male | Adult | 11 birds | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased @ 80 ppm | mortality versus controls | Male | Adult | 21/dose | Toxicity Factor Datasets | 1 yr | Laboratory |
Song Sparrow (Melospiza melodia)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DIMETHOATE | 34% (27% SD) | mean reduction in blood serum cholinesterase activity compared to untreated | Male | Adult | 15-20 sparrows | Christmas tree farms; Sherbrooke, Quebec | Toxicity Factor Datasets | CANADA |
Bullfrog (Lithobates catesbeianus formerly Rana catesbeiana)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
MEXACARBATE | 283 - 800 mg/kg | LD50, estimated | Male | Not Reported | 14 | Toxicity Factor Datasets | Laboratory |
American Kestrel (Falco sparverius)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | blood Se concentration = 1.307 + 0.852(diet Se concentration) | relation between Se concentrations in blood (dry wt) and diet (dry wt) | Male | Adult | 40 birds | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 984.1-1438.6 ppm (dry wt) | brain residues in birds that died | Male | Adult | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 232.9 ppm (dry wt) | mean brain residues in birds that survived | Male | Adult | 11 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 507-877.1 ppm (dry wt) | liver residues in birds that died | Male | Adult | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 88.1 ppm (dry wt) | mean liver residues in birds that survived | Male | Adult | 11 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
FENTHION | 100% | Male | Adult | 14 | Toxicity Factor Datasets | Laboratory | ||
FENTHION | 77.9-92% | range of brain acetylcholinesterase inhibition (relative to control) in birds that died | Male | Adult | 14 | Toxicity Factor Datasets | Laboratory | |
FENTHION | 96% | range of plasma cholinesterase inhibition (relative to control) in birds that died | Male | Adult | 14 | Toxicity Factor Datasets | Laboratory |
Deer Mouse (Peromyscus maniculatus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AZINPHOS-METHYL (GUTHION) | 48 mg/kg bw (95% CL: 39-74 mg/kg, slope = 2.57 +/- 0.73SE) | LD50 | Male | Adult | 5-7 animals/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
MERCURY COMPOUNDS | increase and decrease | decreased swimming ability, increased time for mouse to leave circle in center of field, decreased number of lines crossed and increased number of backward movements compared to a reference site | Male | Adult | 7 - 14 animals | Bird Island, Great Salt Lake | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
METHYLCHLORANTHRENE (3-) | 0.14 mg/kg/d | ED50 for immunosuppression, measured as suppression of plaque forming cell response | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 7 - 8 wk | Laboratory | |
METHYLCHLORANTHRENE (3-) | 1.24 mg/kg/d | ED50 for ethoxyresorufin-O-dealkylase (EROD) activity | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 7 - 8 wk | Laboratory | |
DIBENZ[A]ANTHRACENE (1,2,5,6-) | 0.048 mg/kg/d | ED50 for immunosuppression, measured as suppression of plaque forming cell response | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 7 - 8 wk | Laboratory | |
DIBENZ[A]ANTHRACENE (1,2,5,6-) | 0.85 mg/kg/d | ED50 for ethoxyresorufin-O-dealkylase (EROD) activity | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 7 - 8 wk | Laboratory | |
DIMETHYLBENZ[A]ANTHRACENE (7,12-) | 0.026 mg/kg/d | ED50 for immunosuppression, measured as suppression of plaque forming cell response | Male | Juvenile | Not Reported | Toxicity Factor Datasets | 7 - 8 wk | Laboratory |
Clapper Rail (Rallus longirostris)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | 1612 ppm | 5 day dietary LC50 | Male | Juvenile | 7 birds | Toxicity Factor Datasets | Laboratory | |
DDD (4,4'-), DDT (4,4'-) | 13.3 ppm | mean residue concentration in brains of birds that survived | Male | Juvenile | 7 birds | Toxicity Factor Datasets | Laboratory | |
DDD (4,4'-), DDT (4,4'-) | 42.9 ppm | mean residue concentration in brains of birds that died | Male | Juvenile | 7 birds | Toxicity Factor Datasets | Laboratory |
California Sea Lion (Zalophus californianus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific |
---|---|---|---|---|---|---|---|---|
CADMIUM COMPOUNDS, DDT (Technical Grade Mixture), MERCURY COMPOUNDS, POLYCHLORINATED BIPHENYLS | increase | incidence of kidney histopathological lesions in "sick" or dead animals compared to "healthy" animals, consistent with diagnosis of leptospirosis | Male | Adult | 2-8/group | Toxicity Factor Datasets | 5 - 9 yr |
Mourning Dove (Zenaida macroura)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | no effect | metabolic rate at a range of ambient temperatures | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1254 | no effect | body weight | Male | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1254 | decreased at 40 ppm | body temperature at a range of ambient temperatures | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory |