Female
Pacific Green Turtle (Chelonia mydas)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
PCB | Range: <1.6-48.9 ng/g | Fat concentration | Female | 21 | Sao Paulo | Toxicity Factor Datasets | BRAZIL | |
PCB | Range: <1.6 ng/g | Kidney concentration | Female | 21 | Sao Paulo | Toxicity Factor Datasets | BRAZIL | |
PCB | Range: <1.6-37.7 ng/g | Kidney concentration | Female | 21 | Sao Paulo | Toxicity Factor Datasets | BRAZIL | |
SILVER COMPOUNDS | Tumor score 0: 2.61, score 1: 0.90, score 2: 2.00, score 3: 2.71 µg/g dw | Blood concentration | Female | Juvenile | Tumor score 0: 13, score 1: 4, score 2: 4, score 3: 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
SILVER COMPOUNDS | Tumor score 0: 0.51, score 1: 0.21, score 2: 0.39, score 3: 0.59 µg/g ww | Blood concentration | Female | Juvenile | Tumor score 0: 13, score 1: 4, score 2: 4, score 3: 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
CADMIUM (elemental) | Tumor score 0: 0.39, score 1: 0.17, score 2: 0.26, score 3: 0.35 µg/g dw | Blood concentration | Female | Juvenile | Tumor score 0: 13, score 1: 4, score 2: 4, score 3: 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
CADMIUM (elemental) | Tumor score 0: 0.08, score 1: 0.04, score 2: 0.05, score 3: 0.08 µg/g ww | Blood concentration | Female | Juvenile | Tumor score 0: 13, score 1: 4, score 2: 4, score 3: 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
COPPER (elemental) | Tumor score 0: 4.64, score 1: 5.56, score 2: 6.42, score 3: 8.30 µg/g dw | Blood concentration | Female | Juvenile | Tumor score 0: 13, score 1: 4, score 2: 4, score 3: 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
COPPER (elemental) | Tumor score 0: 0.95, score 1: 1.29, score 2: 1.24, score 3: 1.80 µg/g ww | Blood concentration | Female | Juvenile | Tumor score 0: 13, score 1: 4, score 2: 4, score 3: 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
NICKEL (elemental) | Tumor score 0: 44.07, score 1: 46.74, score 2: 57.85, score 3: 50.01 µg/g dw | Blood concentration | Female | Juvenile | Tumor score 0: 13, score 1: 4, score 2: 4, score 3: 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
NICKEL (elemental) | Tumor score 0: 9.15, score 1: 11.20, score 2: 10.99, score 3: 11.22 µg/g ww | Blood concentration | Female | Juvenile | Tumor score 0: 13, score 1: 4, score 2: 4, score 3: 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
LEAD (elemental) | Tumor score 0: 4.77, score 1: 3.77, score 2: 7.76, score 3: 11.15 µg/g dw | Blood concentration | Female | Juvenile | Tumor score 0: 13, score 1: 4, score 2: 4, score 3: 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
LEAD (elemental) | Tumor score 0: 0.98, score 1: 0.95, score 2: 1.43, score 3: 2.41 µg/g ww | Blood concentration | Female | Juvenile | Tumor score 0: 13, score 1: 4, score 2: 4, score 3: 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
ZINC (elemental) | Tumor score 0: 3.44, score 1: 2.00, score 2: 3.62, score 3: 5.10 µg/g dw | Blood concentration | Female | Juvenile | Tumor score 0: 13, score 1: 4, score 2: 4, score 3: 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
ZINC (elemental) | Tumor score 0: 0.66, score 1: 0.47, score 2: 0.64, score 3: 1.14 µg/g ww | Blood concentration | Female | Juvenile | Tumor score 0: 13, score 1: 4, score 2: 4, score 3: 6 | Sao Paulo | Toxicity Factor Datasets | BRAZIL |
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | ST = 0.986 - 0.060C | regression equation relating shell thickness (mm) to log10 yolk concentration (C, ug/g); r2=0.54 | Female | Adult | 63 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | no effect | mean daily food consumption rate (166.4 g food/kg body weight) | Female | Adult | 5-10/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | increase @ 100-200 ug/g | estradiol metabolism and cytochrome P450 concentration | Female | Adult | 4/dose/sampling time | Toxicity Factor Datasets | 80 d at initiation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEPTOPHOS | decreased @ 270 ppm | brain weight compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
LEPTOPHOS | decreased @ all doses | activity of brain and plasma cholinesterase, and brain neurotoxic esterase compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
LEPTOPHOS | decreased @ 60, 270 ppm | plasma alkaline phosphatase activity compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254, DDE (4,4'-) | see citation | figure of # eggs/female/wk over time | Female | Adult | 10/dose | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 373 (95% CL; 152-574) ppm lipid basis @ 40 ppm diet | DDE residue concentrations in eggs | Female | Adult | 12 | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1254, DDE (4,4'-) | 344 (95% CL; 156-686) ppm DDE lipid basis and 346 (95%CL; 133-686) ppm PCB lipid basis @ 40 ppm DDE + 40 ppm PCB diet | mean DDE and PCB residue levels in eggs | Female | Adult | 13 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CYANIDE | no effect | rhodanese and 3-mercaptopyruvate sulfurtransferase activities in liver and heart versus controls | Female | Adult | 5/treatment | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), LEAD COMPOUNDS, MERCURY COMPOUNDS | decreased with both treatments | eggshell thickness versus controls | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 78.2 (carcass); 61.6 (egg); 4.1 (brain) ppm, wet wt | DDE residues in whole carcass, egg contents, and brain | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
MERCURY COMPOUNDS | 2.5 (carcass); 1.25 (egg); 23.7 (kidney) ppm, wet wt | mercury residues in whole carcass, egg contents, and kidneys | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
LEAD COMPOUNDS | 3.7 (carcass); 2.5 (egg); 2.5 (eggshells); 9.6 (bone) ppm, wet wt @ 100 ppm lead; 3.4 (carcass); 0.88 (egg); 2.8 (eggshells); 35.0 (bone) ppm, wet wt @ 100 ppm lead + DDE |
lead residues in whole carcass, egg contents, eggshells, and bone | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | no effect | egg production versus controls | Female | Adult | 20 females/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | reduced @ 7 ppm Se | body weight versus controls | Female | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory | |
BORIC ACID, SELENOMETHIONINE | reduced @ 7 ppm Se | hatching success versus controls | Female | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | no effect | Ca - ATPase activity in eggshell glands versus controls | Female | Adult | 5 hens; 19 eggs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1242 | decrease @ 150 ppm | body weight at 6, 8 and 12 wks of treatment | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1242 | no effect @ 150 ppm | embryo mortality, # infertile eggs/clutch or # eggs hatched/clutch | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1242 | 8.9% decrease @ 150 ppm | eggshell thickness, compared to control | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1242 | 105.0 (7.7 SE) mg Aroclor 1260/kg egg @ 150 ppm | PCB concentration in eggs (PCB resembled Aroclor 1260 profile most closely) | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | behavior of offspring; latency in response to approach a maternal call and distance travelled from a frightening stimulus | Female | Adult | 4 adults/dose; 141-175 offspring/dose | Toxicity Factor Datasets | 10 mo | Laboratory | |
DDE (4,4'-) | 0.021 - 0.028 ppm wet wt @ 0 ppm; 5.8 (0.32 SE; range 4.28-7.23) ppm wet wt @ 3 ppm | mean and range of DDE egg concentrations | Female | Adult | 8 eggs/dose | Toxicity Factor Datasets | 10 mo | Laboratory | |
DDE (4,4'-) | increase @ 3 ppm | responsiveness of offspring to maternal call; % that approached call and % that spent 100% of time near call after initial approach | Female | Adult | 4 adults/dose; 148-156 offspring/dose | Toxicity Factor Datasets | 10 mo | Laboratory | |
DDE (4,4'-) | decrease @ 3ppm | decrease in distance traveled in those offspring that traveled more than 10 cm from a frightening stimulus | Female | Adult | 4 adults/dose; 64-71 offspring/dose | Toxicity Factor Datasets | 10 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CYANIDE | increased @ 1, 2 mg/kg bw | serum creatine kinase activity versus controls | Female | Adult | at least 5 determinations/group | Toxicity Factor Datasets | Laboratory | |
CYANIDE | decreased @ 0.5,1,2 mg/kg bw | respiratory control ratios in heart, liver and brain versus controls | Female | Adult | at least 5 determinations/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 1.23 +/- 0.12 ug/g wet weight | mean +/- SE p,p'-DDE concentration in shell gland mucosa | Female | Adult | Not Reported | Toxicity Factor Datasets | 1 yr | Laboratory | |
DDE (4,4'-) | 28% decrease @ 40 mg/kg | eggshell index (shell weight/shell length x breadth), compared to control | Female | Adult | 9-20/group | Toxicity Factor Datasets | 1 yr | Laboratory | |
DDE (4,4'-) | no effect | plasma calcium concentration | Female | Adult | Not Reported | Toxicity Factor Datasets | 1 yr | Laboratory | |
DDE (4,4'-) | 25% decrease @ 40 mg/kg | calcium content of secreted fluid in the shell gland, compared to control | Female | Adult | 5/dose | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase | length of reproductive cycle; due to prolonged phase of gonadal maturation | Female | Adult | 17 pairs/dose | Toxicity Factor Datasets | 10 mo | Laboratory | |
CRUDE OILS | no effect | clutch size | Female | Adult | 17 pairs/dose | Toxicity Factor Datasets | 10 mo | Laboratory | |
CRUDE OILS | decrease | % hatchability (53% @ 3ml/100g vs 71% in controls) | Female | Adult | 17 pairs/dose | Toxicity Factor Datasets | 10 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | 9.2(0.52) ppm with seleno-D,L-methionine; 8.9(0.35) ppm with seleno-L-methionine; 6.6(0.37) ppm with selenized yeast | mean(SE) wet wt concentrations of selenium in 8th egg laid | Female | Adult | 15 pairs/treatment group, 10 pairs/control group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease | % fertile eggs and # of ducklings; when male, female or both male and female exposed to oil, compared to control | Female | Adult | 3 pairs/dose | Toxicity Factor Datasets | 5.5 mo at initiation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | lead only: 112.27 (+/- 44.27); lead-iron: 32.65 (+/- 16.58) ppm, wet wt | lead concentration in bone (mean +/- SE) | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
LEAD (elemental) | lead only: 0.71 (+/- 0.25); lead-iron: 0.31 (+/- 0.06) ppm, wet wt | lead concentration in blood (mean +/- SE) | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | decreased with Pb | liver weight versus controls (females only) | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no effect with Fe or Bi | onset of lay and time to lay 21 eggs versus controls | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), DDT (4,4'-) | see citation | figure of eggshell thickness over 30 d period (significant differences noted at various times) | Female | Adult | 20/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM | decreased @ 30, 100, 300 ppm | growth rate versus controls | Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory |
Peregrine Falcon (Falco peregrinus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), POLYCHLORINATED BIPHENYLS | 11% decrease | eggshell thickness compared to pre-1947 reference eggs | Female | Adult | 112 eggs | eastern U.S. coast | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Condition | Countries |
---|---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE | 0.9-7.2 (DDT); 10.4-41.8 (DDE); 0.9-3.4 (DDD); 0.3-2.0 (dieldrin); 0.2-1.2 (heptachlor epoxide) | range of concentrations in eggs (ppm, wet wt) | Female | Adult | 7 eggs | Peace, Slave, and Mackenzie Rivers | Toxicity Factor Datasets | CANADA | |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE | 37.3 (DDT), 284 (DDE), 39.5 (DDD), 3.3 (dieldrin), 4.4 (heptachlor epoxide) | mean residue concentrations in fat (ppm, wet wt) | Female | Adult | 9 birds | Peace, Slave, and Mackenzie Rivers | Toxicity Factor Datasets | nesting | CANADA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
AROCLOR 1248, AROCLOR 1254, AROCLOR 1260, DDE (4,4'-), DDT (4,4'-), MERCURY COMPOUNDS | no effect | eggshell thickness compared to pre-1947 reference eggs | Female | Adult | 9 eggs | urban nest sites | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 13.1% and 13.6% decreases in tundrius and anatum ssp. | eggshell thickness compared to pre-1947 reference eggs | Female | Adult | 21 and 34 eggs for tundrius and anatum ssp. | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN | 48.0 (DDE), 3.35 (DDD), 1.02 (DDT), 1.45 (dieldrin) | mean concentrations of pesticides in eggs (ppm, dry weight) | Female | Adult | 2 eggs | Yukon River | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 6.4-33 ppm, dry wt | range of concentrations in whole addled eggs | Female | Adult | 5 eggs from 3 clutches | Toxicity Factor Datasets | |
DDE (4,4'-) | 14.2% | percent eggshell thinning compared to pre-1947 reference eggs | Female | Adult | 26 breeding attempts | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | review | eggshell thickness compared to that of pre-1945 eggs | Female | Adult | Not Reported | Toxicity Factor Datasets | GLOBAL |
American Kestrel (Falco sparverius)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DICOFOL | decreased 5.45% (@ 5 mg/kg), 10.98% (@ 20 mg/kg) | eggshell thickness compared to controls | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
DICOFOL | non-detectable (@ 5 mg/kg), 560 ng/g (@ 20 mg/kg) | mean concentration of metabolite dichlorobenzophenone in eggs | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
DICOFOL | increased @ 5 mg/kg | numbers of chicks or eggs lost (destroyed) by breeding male and female offspring of dicofol-treated females versus controls | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
DICOFOL | no effect | eggshell thickness for breeding female offspring of dicofol-treated females versus controls | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | 1.05 (0.05 SE) ppm (wet wt) | lead concentration in liver | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | 0.70 (0.20 SE) ppm (wet wt) | lead concentration in tibia | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | 232 (9 SE) ppm (wet wt) | DDE concentration in carcass | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254, PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL), PCB 77 (3,3',4,4'-TETRACHLOROBIPHENYL) | increased with PCB 77 | liver weight (as percent of body weight) versus controls | Female | Adult | 4/treatment group | Toxicity Factor Datasets | Laboratory |
Deer Mouse (Peromyscus maniculatus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
CHLOROCHOLINE CHLORIDE | increase @ 80 mg/kg bw/d | plaque forming cells/g spleen | Female | Adult | 12/dose | Toxicity Factor Datasets | Laboratory | |
CHLOROCHOLINE CHLORIDE | decrease @ 80 mg/kg bw/d | reciprocal of hemolysin titers (against sheep rbc) | Female | Adult | 12/dose | Toxicity Factor Datasets | Laboratory | |
GLYPHOSATE | increase @ 20, 80 mg/kg bw/d | liver weight to body weight ratio | Female | Adult | 12/dose | Toxicity Factor Datasets | Laboratory | |
GLYPHOSATE | increased @ 1-80 mg/kg | thymus weight to bw ratio | Female | Adult | 12/dose | Toxicity Factor Datasets | Laboratory | |
GLYPHOSATE | increase@ 80 mg/kg bw/d | white blood cell count | Female | Adult | 12/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DICHLOROPHENOXY-ACETIC ACID (2,4-) | no effect | mean litter size, based upon number of viable embryos or placental scars | Female | Adult | 66-77 animals | Gunnison County and Saquache County, (elev., 8500 - 9300 ft.) | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|
ALDICARB | no effect | growth rate estimated by changes in body weight | Female | 8 animals/dose | Toxicity Factor Datasets | 29 - 32 d | Laboratory | |
ALDICARB | no effect | daily activity measured as time spend in burrow or moving in/out of burrow | Female | 8 animals/dose | Toxicity Factor Datasets | 29 - 32 d | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | no effect | number of litters per 100 breeding females, measured by observing litters in nesting boxes at a control and roadside site | Female | Adult | 50 nesting boxes, 66 observation periods nimals | Interstate 25, Denver (elev. 1884-2018 m) | Toxicity Factor Datasets |
Double-crested Cormorant (Phalacrocorax auritus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
MERCURY (elemental), POLYCHLORINATED BIPHENYLS | 5.7 ppm wet wt PCBs | concentration in eggs | Female | Adult | 5 eggs | Lake Pointsett, Dry Lake | Toxicity Factor Datasets |
MERCURY (elemental), POLYCHLORINATED BIPHENYLS | 0.29 ppm wet wt mercury | mean concentration in eggs | Female | Adult | 5 eggs | Lake Pointsett, Dry Lake | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), POLYCHLORINATED BIPHENYLS | 28.8% decrease | mean thickness of eggshells collected in 1969 compared with pre-1946 museum specimens | Female | Adult | 17 eggs | Anacapa Island | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), POLYCHLORINATED BIPHENYLS | 38.3% decrease | mean thickness of eggshells collected in 1969 compared with pre-1946 museum specimens | Female | Adult | 23 eggs | Los Coronados Island | Toxicity Factor Datasets |
Mourning Dove (Zenaida macroura)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | no effect | progesterone concentration in blood | Female | Adult | 10-13/group | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1254 | earlier @ 10 ppm | timing of peak progesterone concentration in blood | Female | Adult | 10-13/group | Toxicity Factor Datasets | Laboratory |
Northern Flicker (Colaptes auratus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDT (Technical Grade Mixture) | no effect | eggshell thickness | Female | Adult | 8 eggs (reference), 12 eggs (treatment) | NE Oregon, SE Washington, Idaho | Toxicity Factor Datasets |
Great Horned Owl (Bubo virginianus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE | no effect | eggshell thickness compared to pre-1946 museum speciments | Female | Adult | 3 eggs | south-central Montana | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
AROCLOR 1254, DDE (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, OXYCHLORDANE | 5% decrease | eggshell thickness index compared with reference eggs | Female | Adult | 18 eggs, 15 clutches | Butler, Delaware, Hamilton Counties | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), POLYCHLORINATED BIPHENYLS | increased | mortality due to PCB intoxication, based on brain residues | Female | Adult | 1 owl | Greene County | Toxicity Factor Datasets |
California Brown Pelican (Pelecanus occidentalis ssp. californicus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | significantly decreased compared to pre-1943 samples | eggshell thickness (of intact or broken eggshells) | Female | Adult | 86 eggs | Anacapa Island and Isla Coronado Norte | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | non-detectable DDT plus TDE, 96.6 ppm DDE, lipid wet basis | concentration in egg contents | Female | Adult | 39 eggs | Anacapa Island and Isla Coronado Norte | Toxicity Factor Datasets |
California Sea Lion (Zalophus californianus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
CADMIUM COMPOUNDS, CHROMIUM COMPOUNDS, COPPER COMPOUNDS, LEAD COMPOUNDS, SELENIUM COMPOUNDS, ZINC COMPOUNDS | increase | incidence of epileptiform seizures and subsequent death associated with "unusual" Se levels | Female | Adult | 1 | Toxicity Factor Datasets | 18 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific |
---|---|---|---|---|---|---|---|---|
DDT (Technical Grade Mixture), POLYCHLORINATED BIPHENYLS | increase | incidence of premature parturtion associated with elevated DDT and PCB residues, compared to full term parturient group | Female | Adult | 4-6/group | San Miguel Island | Toxicity Factor Datasets | 6 - 15 yrs |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
ALDRIN, DDT (Technical Grade Mixture), DIELDRIN, ENDRIN, HEPTACHLOR, HEPTACHLOR EPOXIDE, LINDANE | review | eggshell breakage, weight and thickness compared to 1950 measurements | Female | Adult | Not Reported | Toxicity Factor Datasets | UNITED KINGDOM |
Burrowing Owl (Athene cunicularia formerly Speotyto cunicularia)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
HEPTACHLOR | no effect | mean clutch size | Female | Adult | 6 nests | Columbia Basin | Toxicity Factor Datasets |