Anas platyrhynchos
Mallard duck (Anas platyrhynchos)
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| CRUDE OILS | no effect | onset of laying, egg production, egg fertility, compared to controls | Female | Adult | 20 hens/dose | Toxicity Factor Datasets | Laboratory | |
| CRUDE OILS | decrease | egg hatchability (# eggs hatching/# fertile eggs), compared to controls | Female | Adult | 20 hens/dose | Toxicity Factor Datasets | Laboratory | |
| DDE (4,4'-) | no effect | onset of laying, egg production, egg fertility and egg hatchability, compared to controls | Female | Adult | 20 hens/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| PHOSPHORUS (YELLOW OR WHITE) | 6.96 mg/kg bw (2.66-8.96 95% CI) | 24 hour median lethal dose | Female | Adult | 6 birds/dose | Toxicity Factor Datasets | Laboratory | |
| PHOSPHORUS (YELLOW OR WHITE) | 6.46 mg/kg bw (5.19-7.69 95% CI) | 24 hour median lethal dose | Male | Adult | 4-5 birds/dose | Toxicity Factor Datasets | Laboratory | |
| PHOSPHORUS (YELLOW OR WHITE) | 3.90 mg/kg bw (3.24-4.69 95% CI) | 24 hour median lethal dose | Female | Adult | 4-5 birds/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| AROCLOR 1254 | increased @ 100, 250, 500 mg/kg bw | thyroid wt/body wt and liver wt/body wt ratios versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory | |
| AROCLOR 1254 | increased @ 20,100, 250, 500 mg/kg bw | hepatic microsomal EROD and PROD activities versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory | |
| AROCLOR 1254 | decreased @ 20, 100, 250, 500 mg/kg bw | plasma triiodothyronine concentrations versus controls | Male | Adult | 6-12/dose | Toxicity Factor Datasets | 1-2 yr | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| EMAMECTIN BENZOATE | no effect | microscopic changes to brain, spinal cord, or peripheral nerves versus controls | Both Male and Female | Adult | 16 pairs/group | Toxicity Factor Datasets | 22 weeks | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| BORIC ACID, SELENOMETHIONINE | reduced @ 900 ppm B | body weight versus controls | Both Male and Female | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory | |
| BORIC ACID, SELENOMETHIONINE | decreased @ 900 ppm B | liver weight versus 450 ppm B group | Male | Adult | 14 pairs/treatment | Toxicity Factor Datasets | 1 yr | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| LEAD COMPOUNDS | no effect | body weight versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
| LEAD COMPOUNDS | increased @ 869 and 954 ug/g | protoporphyrin versus corn or complete diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory | |
| LEAD COMPOUNDS | reduced @ 828 ug/g | hemoglobin concentrations versus controls | Male | Adult | 10/ Pb treatment; 20/control treatment | Toxicity Factor Datasets | approx. 5 mo | Laboratory | |
| LEAD COMPOUNDS | reduced @ 869 and 954 ug/g | delta aminolevulinic acid dehydratase activity versus corn or complete diet controls | Male | Adult | 5/ Pb treatment;3/control treatments | Toxicity Factor Datasets | approx. 7 mo | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 250.6(39.0) ppm in femur, 78.3(9.7) ppm in liver, 256.3(22.2) in kidneys | mean(SE) dry wt lead concentrations in tissues of lead-dosed birds | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory | |
| LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 4.3(0.7) ppm in femur, non-detect. in liver, 2.4(0.2) in kidneys | mean(SE) dry wt tungsten concentrations in tissues of tungsten-polymer-dosed birds | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| METHYLMERCURY CHLORIDE, SELENOMETHIONINE | increased @ 10 ppm Se | hepatic GSSG reductase activity versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory | |
| METHYLMERCURY CHLORIDE, SELENOMETHIONINE | increased @ 10 ppm Hg | oxidized glutathione (GSSG) level versus controls | Male | Adult | 12/treatment | Toxicity Factor Datasets | 18 mo | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | increased with Fe | weight of eggs that hatched versus controls | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
| BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | increased with Bi | weight of eggs that did not hatch versus controls | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| SELENITE, SODIUM, SELENOMETHIONINE | decreased | blood monocyte counts after 78 days exposure versus controls | Male | Adult | Controls = 24 Treated = 8 |
Laboratory | Toxicity Factor Datasets | Laboratory |
| SELENITE, SODIUM, SELENOMETHIONINE | increased @ 3.5 mg/L (selenite) or 2.2 mg/L (selenomethionine) | serum ALT enzyme activity versus controls n high selenite and selenomethionine groups. | Male | Adult | Controls = 24 Treated = 8 |
laboratory | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| SELENOMETHIONINE | increased @ 15 (GSH-peroxidase only), 60 ppm Se, adequate protein | plasma GSH-peroxidase and alkaline phosphatase activities versus controls | Not Reported | Juvenile | 15/group | Toxicity Factor Datasets | 1-day old | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| ALDICARB | 6.73 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 30 days | Laboratory | |
| MONOCROTOPHOS | 5.86 (4.70-7.29), 7.21 (5.79-8.98), 5.10 (4.44-5.86), 3.36 (2.77-4.09) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hr, 7 d, 30 d, or 6 mos | Laboratory | |
| ALDICARB | 4.44 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 6 mos | Laboratory | |
| PROPOXUR | 7.38 (5.97-9.14), 12.7 (10.2-15.9), 14.6 (12.4-17.4), 9.58 (7.61-12.1) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hr, 7 d, 30 d, or 6 mos | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| DDT (4,4'-) | decreased | eggshell weight versus controls | Female | Adult | 5 hens; 19 eggs | Toxicity Factor Datasets | Laboratory | |
| DDT (4,4'-) | decreased | eggshell quality (R-value) versus controls | Female | Adult | 5 hens; 19 eggs | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| CADMIUM CHLORIDE | no effect | brain, liver, kidney, testes weights versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory | |
| CADMIUM CHLORIDE | no effect | liver glycogen concentration versus controls | Male | Adult | 8 | Toxicity Factor Datasets | 32 weeks | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| SELENITE, SODIUM, SELENOMETHIONINE | increased @ 40, 80 ppm selenite or selenomethionine | duckling mortality versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | Laboratory | |
| SELENITE, SODIUM, SELENOMETHIONINE | decreased | food consumption versus controls | Not Reported | Juvenile | 40 birds/group | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| DDT (4,4'-) | no effect | hepatic microsomal enzyme activity (aniline hydroxylase and aminopyrine N-demethylase) | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory | |
| DIELDRIN | no effect | hepatic microsomal enzyme activity (aniline hydroxylase and aminopyrine N-demethylase) | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| AROCLOR 1242 | no effect @ 150 ppm | weight and survival of offspring (exposed in ovo) fed control diet after hatching for 3 wks | Female | Adult | 12 pairs/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| DICOFOL | 2-12% decrease @ 10-100 ug/g | eggshell thickness, compared to controls | Female | Adult | 4-8/dose | Toxicity Factor Datasets | Laboratory | |
| DICOFOL | 5.4 (0.3 SE) ug/g wet wt. @ 3 ug/g diet; 18.1 (1.2 SE) @ 10 ug/g diet; 37.1 (1.6 SE) @ 30 ug/g diet; 150.7 (9.9SE) @ 100 ug/g diet, | mean egg yolk concentrations of p,p'-dicofol after 37-42 d on dicofol diet | Female | Adult | 4-8/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| DDT (Technical Grade Mixture) | decrease @ 20 - 200 ppm | eggshell thickness, weight and calcium concentration | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory | |
| DDT (Technical Grade Mixture) | increase @ 200 ppm | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| LINDANE | 62 lbs AI/acre (slope = 8.13) for exposure of 3d embryo; 52 lbs AI/acre (slope = 9.19) for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | Toxicity Factor Datasets | 3 or 8d of development | Laboratory | |
| PARAQUAT | 1.5 lbs AI/acre (slope = 1.66) for exposure of 3d embryo; 2.5 lbs AI/acre (slope = 1.40) for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | Toxicity Factor Datasets | 3 or 8d of development | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| CHLORPYRIFOS | no effect | fertility and hatchability of eggs, and duckling survival to 14 days | Not Reported | Juvenile | 24 pairs/dose | Toxicity Factor Datasets | 7 and 11 months old | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| DICROTOPHOS, FENTHION | 68-78% | maximal brain acetylcholinesterase activity inhibition compared to control (after 3 days treatmentt) | Not Reported | Juvenile | 4/group | Toxicity Factor Datasets | 1 day old | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
|---|---|---|---|---|---|---|---|---|
| CARBOFURAN | decreased @ 132 g/ha (150, 300 m exposure distances), 264 g/ha (all exposure distances) | brain cholinesterase activities compared with controls | Not Reported | Juvenile | 8/group | Toxicity Factor Datasets | CANADA | |
| CARBOFURAN | no effect | growth rate to four weeks of age compared with controls | Not Reported | Juvenile | 8/group | Toxicity Factor Datasets | CANADA |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| MALATHION | 49.5 lb/acre | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory | |
| DIAZINON | 9.7 (day 3), 11.1 (day 8) lb/acre | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | Toxicity Factor Datasets | Day 3 or 8 of incubation | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| LEPTOPHOS | 5/5 @ 260 ppm | incidence of ataxia | Both Male and Female | Juvenile | 3-5/group | Toxicity Factor Datasets | 14 d | Laboratory | |
| LEPTOPHOS | 4/5 @ 260 ppm | incidence of CNS lesions | Both Male and Female | Juvenile | 3-5/group | Toxicity Factor Datasets | 14 d | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| CRUDE OILS | 53% increase | plasma triiodothryonine concentration | Not Reported | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
| CRUDE OILS | 56% increase | hepatic cytochrome P450 content | Not Reported | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| AROCLOR 1254, DDE (4,4'-) | see citation | figure of # eggs/female/wk over time | Female | Adult | 10/dose | Toxicity Factor Datasets | Laboratory | |
| DDE (4,4'-) | 373 (95% CL; 152-574) ppm lipid basis @ 40 ppm diet | DDE residue concentrations in eggs | Female | Adult | 12 | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| CRUDE OILS | decrease @ 2.5 - 5% | hematocrit, compared to control | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory | |
| CRUDE OILS | increase @ 0.25 - 5.0% | plasma alanine aminotransferase activity, from liver | Both Male and Female | Juvenile | 10/dose | Toxicity Factor Datasets | 0-8 wks post-hatch | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| IRON (elemental), LEAD (elemental) | no effect | serum enzyme levels versus controls (at 30 or 60 d post dose) | Male | Adult | 2/group | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| CYANIDE | decreased @ all doses | ATP levels in liver and brain tissues versus controls | Female | Adult | 5/treatment | Toxicity Factor Datasets | Laboratory | |
| CYANIDE | no effect | ATP levels in heart versus controls | Female | Adult | 5/treatment | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| LEAD (elemental) | decreased with increasing lead in bone | number of eggs laid | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
| LEAD (elemental) | increased with lead shot (egg contents: 0.50 +/-0.06; egg shell: 2.80 +/-0.25 ppm, wet wt) and lead-iron shot (egg shell: 1.42 +/-0.26 ppm, wet wt) | lead in egg contents and shell (mean +/- SE) versus controls | Female | Adult | control=10 eggs; treatment=20 eggs | Toxicity Factor Datasets | 6 mos | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| LEAD (elemental) | increased in all groups dosed with lead shot | incidence of clinical signs, weight loss, breast muscle atrophy | Both Male and Female | Adult | treatment = 10/group control = 5 |
Toxicity Factor Datasets | Laboratory | |
| LEAD (elemental) | increased with Pb/corn+Ca (50%), and Pb/corn only (100%) | % mortality versus controls | Both Male and Female | Adult | treatment = 10/group control = 5 |
Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
|---|---|---|---|---|---|---|---|---|
| LEAD COMPOUNDS | humerus, 41.652 (8.20-211.6); spleen, 0.669 (0.128-2.397); pancreas, 3.295 (1.074-13.47); brain, 1.367 (0.120-117.1) | geometric mean concentrations (ranges) in humerus, spleen, pancreas, and brain | Not Reported | Not Reported | 6-10 birds/tissue type | Ebro Delta Natural Park | Toxicity Factor Datasets | ITALY |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| ARSENATE, SODIUM, SELENOMETHIONINE | increased (100%) @ 60 ppm Se and (53%) @ 200 ppm As | incidence of mortality versus controls | Not Reported | Juvenile | 15 birds/group | Toxicity Factor Datasets | 1 d | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| ALUMINUM SULFATE | increased in LL diets | incidence of clinical signs (LL vs. LH vs. NN diets) | Not Reported | Juvenile | 12-14/group | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| CADMIUM CHLORIDE | no effect | mortality versus controls | Both Male and Female | Adult | 20 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory | |
| CADMIUM CHLORIDE | no effect | body wt, hematocrit, hemoglobin, food consumption versus controls | Both Male and Female | Adult | 20 pairs/group | Toxicity Factor Datasets | 1 yr | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| METHYLMERCURY DICYANDIAMIDE | decreased @ 0.5, 3 ppm | duration of egg production compared to controls | Female | Adult | 10 females, 3 males/dose | Toxicity Factor Datasets | Laboratory | |
| METHYLMERCURY DICYANDIAMIDE | decreased @ 3 ppm | hatching success and 1 wk survival of hatchlings compared to controls | Not Reported | Juvenile | 10 females, 3 males/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| SELENIUM COMPOUNDS, SELENOMETHIONINE | 11-12 (@ 15 ppm as Se-met or wheat), 6.2 (@ 15 ppm as yeast), 19-20 (@ 30 ppm as Se-met or wheat), 9.9 (@ 30 ppm as yeast) ppm, wet wt | mean concentrations of Se in livers | Not Reported | Juvenile | 25 birds/group | Toxicity Factor Datasets | 1 day | Laboratory | |
| SELENIUM COMPOUNDS, SELENOMETHIONINE | decreased @ 30 ppm (as Se-met or yeast) | food consumption compared to controls | Not Reported | Juvenile | 25 birds/group | Toxicity Factor Datasets | 1 day | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| SELENOMETHIONINE | decreased @ 8, 16 ppm | hatchability compared to controls | Not Reported | Juvenile | 5-11 pairs/group | Toxicity Factor Datasets | Laboratory | |
| SELENITE, SODIUM, SELENOMETHIONINE | increased @ 10,25 ppm (as selenite), 10 ppm (as selenomethionine) | number of embryos showing malformations or embryotoxicity compared to controls | Not Reported | Embryo | 5-11 pairs/group | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| SELENOMETHIONINE | increased @ 32 ppm | plasma alkaline phosphatase activity and total protein levels versus controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory | |
| SELENOMETHIONINE | decreased @ 32 ppm | body weight, liver DNA:RNA ratio, hematocrit compared to controls | Male | Adult | 10 birds/group | Toxicity Factor Datasets | 2 yr | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| METHYLMERCURY DICYANDIAMIDE | no effect | body weight versus controls | Both Male and Female | Adult | 14 pairs/group | Toxicity Factor Datasets | Laboratory | |
| METHYLMERCURY DICYANDIAMIDE | increased in 2nd generation | food consumption versus controls | Both Male and Female | Adult | 14 pairs/group | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| PENTACHLOROPHENOL | decrease @ 961 ug/g | total body weight, compared to control; reported as the LOAEL for the study | Not Reported | Juvenile | 6/dose | Toxicity Factor Datasets | 4 d | Laboratory | |
| PENTACHLOROPHENOL | no effect @ 423.2 ug/g | total body weight, compared to control; reported as the NOAEL for the study | Not Reported | Juvenile | 6/dose | Toxicity Factor Datasets | 4 d | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| DDE (4,4'-) | 25% decrease @ 40 mg/kg | calcium content of secreted fluid in the shell gland, compared to control | Female | Adult | 5/dose | Toxicity Factor Datasets | 1 yr | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| BORIC ACID | decrease @ 1600 ppm | hematocrit and hemoglobin concentration, compared to controls | Both Male and Female | Juvenile | 10 animals/pen; 3 pens/dose | Toxicity Factor Datasets | 1 d | Laboratory | |
| BORIC ACID | increase @ 100, 400, 1600 ppm | plasma triglyceride concentration (21-42% increase, compared to controls) | Both Male and Female | Juvenile | 10 animals/pen; 3 pens/dose | Toxicity Factor Datasets | 1 d | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| FUEL OILS | decrease @ 4.0, 7.0, 12.0 ml/kg/d | mean spleen index (spleen wt./body wt.) | Male | Adult | 4-5/dose | Toxicity Factor Datasets | Laboratory | |
| COREXIT 9527 | no effect | % mortality, compared to controls | Male | Adult | 6/dose | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| EMAMECTIN BENZOATE | 76 mg/kg bw, 56-102 (95% CI) | acute oral LD50 | Both Male and Female | Adult | 10/dose | Toxicity Factor Datasets | 19 weeks | Laboratory | |
| EMAMECTIN BENZOATE | < 25 mg/kg bw | no-observed-effect level, based on body weight loss | Both Male and Female | Adult | 10/dose | Toxicity Factor Datasets | 19 weeks | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with selenized yeast | body weight of 6 day old ducklings versus controls | Both Male and Female | Both Adults and Juveniles | 15 pairs/treatment group, 10 pairs/control group | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| SELENOMETHIONINE | no effect | distance run in 2 seconds from a fright stimulus vs controls | Not Reported | Chick | 32, 14, 14, 14, 11 in the 0, 1, 2, 4, and 8 ppm groups | Toxicity Factor Datasets | 6 days | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean survival times compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| DIELDRIN | no effect | body weight at end of experiment | Not Reported | Juvenile | 12/dose | Toxicity Factor Datasets | 1 d at initiation | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| PARATHION | 100% @ 5mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | Toxicity Factor Datasets | 2 weeks old | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| CHLORPYRIFOS | 357 ppm | 11 day dietary LC50 | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
|---|---|---|---|---|---|---|---|---|
| LEAD (elemental) | decreased @ > 60 ug/dl blood | delta-aminolevulinic acid dehydratase activity | Both Male and Female | Not Reported | 21 birds | World Wildlife Fund Refuge, Tuscany | Toxicity Factor Datasets | ITALY |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| CADMIUM CHLORIDE, LEAD CHLORIDE | 7.2 (0.9) ug Pb/g @ 100 ppm Pb; 104.8 (19.1) ug Pb/g @ 100 ppm Cd; 54.2 (3.7) ug Cd/g @ 50 ppm Cd + 50 ppm Pb (dry wt) | mean (SE) concentrations in liver | Male | Juvenile | 6-8 birds/dose | Toxicity Factor Datasets | 128 d (at initiation) | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| ARSENATE, SODIUM | no effect | survival rate versus controls | Both Male and Female | Juvenile | 30 birds/group | Toxicity Factor Datasets | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| STEEL COMPOUNDS, TRIBUTYLTIN | increased in both groups (no treatment diffs) | white blood cell counts, monocyte counts, total protein concentrations over study period | Both Male and Female | Juvenile | 20/group | Toxicity Factor Datasets | 7 wks | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| DDE (4,4'-) | 18% decrease @ 40 mg/kg | eggshell index (shell weight/length x breadth), compared to control | Female | Adult | 18 | Toxicity Factor Datasets | 1 yr | Laboratory |