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Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type California Counties Countries Lab
1,2-DIBROMO-4-(1,2-DIBROMOETHYL)CYCLOHEXANE (DBE-DBCH - FORMERLY TBECH) Earlier Time of laying F Adult 46 pairs McGill University Toxicity Factor Datasets Lab CANADA Laboratory
PBDE TECHNICAL MIXTURE, DE-71 No effect Survival to day 24 Embryo 120 Toxicity Factor Datasets Lab Laboratory
PBDE TECHNICAL MIXTURE, DE-71 See citation Table 1 Egg PBDE congener concentrations at various incubation stages Embryo Toxicity Factor Datasets Lab Laboratory
PBDE TECHNICAL MIXTURE, DE-71 No effect Ulna length Embryo 70 Patuxent Wildlife
Research Center
Toxicity Factor Datasets Lab Laboratory
PCB Increased Plasma T4 F Adult 152 Avian Science and Conservation
Centre of McGill University
Toxicity Factor Datasets Lab CANADA Laboratory
PBDE TECHNICAL MIXTURE, DE-71 Increased HBCD NR Nestling 64 Toxicity Factor Datasets Lab CANADA Laboratory
HDBP (halogenated dimethyl bipyrroles) 1,600 ± 100 ng/g Plasma concentration NR Adult 32 Avian Science and Conservation
Centre of McGill University
Toxicity Factor Datasets Lab CANADA Laboratory
HDBP (halogenated dimethyl bipyrroles) 5.50 ± 0.09 eggs Clutch size Embryo 8 Avian Science and Conservation
Centre of McGill University
Toxicity Factor Datasets Lab CANADA Laboratory
CADMIUM (elemental) See citation figures Egg concentration Embryo 4 different colonies along Sinaloa Coast Toxicity Factor Datasets MEXICO Laboratory
MERCURY (elemental) 0.27 ppm ± 0.11 Egg concentration Embryo 19 Cape Fear River, South Pelican Toxicity Factor Datasets USA Laboratory
PERFLUOROOCTANOIC ACID 1.1 ng/g ww (<1-1.5) Lung concentration Not Reported 5 Cartagena Bay Toxicity Factor Datasets COLUMBIA Laboratory
DDT (4,4'-) 119 ng/g ww (38.8-541) Egg concentration 10 Marsh Island Toxicity Factor Datasets USA Laboratory
DDD (4,4'-) 9.25 ng/g ww ± 9.3 Egg concentration Embryo 8 Colorado River Delta Toxicity Factor Datasets MEXICO Laboratory
DDE (4,4'), SELENIUM COMPOUNDS 0.183 mm (0.170-0.194) Eggshell thickness Embryo 9 Salton Sea Toxicity Factor Datasets Imperial USA Laboratory
CALCIUM 280 µg/g ± 29 Eggshell concentration Embryo 6 Roosevelt Lake Toxicity Factor Datasets USA Laboratory
TRANS-NONACHLOR 0.06 Egg concentration Embryo 22 South San Francisco Bay marshes Toxicity Factor Datasets USA Laboratory
CHROMIUM (elemental) 1.40 µg/g dw Liver concentration NR Hatchling 4 Hamilton Harbour, Western Lake Ontario Toxicity Factor Datasets CANADA Laboratory
CHLORDANE 55 ng/g lw Blubber concentration M Adult 11 Gulf of California Toxicity Factor Datasets MEXICO Laboratory
6.14 Mean days to death B Not Reported 10 USDA National Wildlife Research Center, Fort Collins, CO Toxicity Factor Datasets Lab USA Laboratory
GLYPHOSATE 0.083 % mortality NR Tadpole 24 San Francisco State University Toxicity Factor Datasets Lab USA Laboratory
ROTENONE See citation Mortality NR Tadpole 12 Private lab, Bozeman, MT Toxicity Factor Datasets Lab USA Laboratory
ENDOSULFAN 7 LOEC NR Tadpole 120 University of Pittsburgh Toxicity Factor Datasets Lab USA Laboratory
MERCURY (elemental) See citation Table 1; µg/g ww Total concentrations in brain, liver, tail tissue Not Reported 23 Colusa National Wildlife Refuge (Colusa County); Natomas Basin (Sacramento County); Butte County, Glenn County; Yolo County Toxicity Factor Datasets USA Laboratory
CHROMIUM (elemental) 42.5 ± 7.8 ppb Blood concentration of live-captured 29 Pine Barrens Toxicity Factor Datasets USA Laboratory
ARSENIC (elemental) 91.4 ± 21.7 ppb Skin concentration, dead-captured 20 Pine Barrens Toxicity Factor Datasets USA Laboratory
MALATHION No effect Mass, g M Juvenile 13 Savannah River Ecology Laboratory Toxicity Factor Datasets Lab USA Laboratory
2-AMINO-4,6-DINITROTOLUENE Increased Kidney weight M Adult 42 Toxicity Factor Datasets Lab USA Laboratory
PCB 0.08 Abandoned incubation B Adult F0: 50 pairs University of Saskatchewan Toxicity Factor Datasets Lab CANADA Laboratory
PCB 0.36 Shortened mandible NR Hatchling NR University of Saskatchewan Toxicity Factor Datasets Lab CANADA Laboratory
PCB Increased Antebrachrium: asymptotic size F Nestling 33 pairs Avian Science and Conservation Centre of McGill
University
Toxicity Factor Datasets Lab CANADA Laboratory
PCB Increased Body mass: growth rate M Nestling 33 pairs Avian Science and Conservation Centre of McGill
University
Toxicity Factor Datasets Lab CANADA Laboratory
PBDE MIXTURE Increased Body mass, 27 d M Nestling 5 Toxicity Factor Datasets Lab CANADA Laboratory
HEXABROMOCYCLODODECANE (HBCDD) No effect Eggshell thickness NR Embryo 28 Toxicity Factor Datasets Lab CANADA Laboratory
PBDE MIXTURE Increased Plasma TT4 F Nestling Environment Canada Toxicity Factor Datasets Lab CANADA Laboratory
HYDROMORPHONE HYDROCHLORIDE 112.1 mg/mL at 5 m post dose Plasma concentration B Adult 12 Toxicity Factor Datasets Lab USA Laboratory
PCB See citation Plasma corticosterone concentration M Adult 18 Avian Science and Conservation Centre of McGill University Toxicity Factor Datasets Lab CANADA Laboratory
PBDE TECHNICAL MIXTURE, DE-71 Increased Perivitelline layer sperm count M Adult 21 Avian Science and
Conservation Centre at McGill University
Toxicity Factor Datasets Lab CANADA Laboratory
1,2-DIBROMO-4-(1,2-DIBROMOETHYL)CYCLOHEXANE (DBE-DBCH - FORMERLY TBECH) Decreased Number fertile eggs F Adult 46 pairs McGill University Toxicity Factor Datasets Lab CANADA Laboratory
PBDE TECHNICAL MIXTURE, DE-71 No effect Pipped egg Embryo 120 Toxicity Factor Datasets Lab Laboratory
OCTA-BROMINATED DIPHENYL ETHER MIXTURE (OCTA-BDE; DE-79) See citation Table 3 Egg octa-BDE congener concentrations at various incubation stages Toxicity Factor Datasets Lab Laboratory
PBDE TECHNICAL MIXTURE, DE-71 Decreased Thyroid weight Embryo 70 Patuxent Wildlife
Research Center
Toxicity Factor Datasets Lab Laboratory
PCB Decreased Plasma T3 M Nestling 46 Avian Science and Conservation
Centre of McGill University
Toxicity Factor Datasets Lab CANADA Laboratory
PBDE TECHNICAL MIXTURE, DE-71 See citation Table 1 Retinol NR Nestling 64 Toxicity Factor Datasets Lab CANADA Laboratory
HDBP (halogenated dimethyl bipyrroles) 18,900 ± 300 ng/g Carcass concentration NR Adult Avian Science and Conservation
Centre of McGill University
Toxicity Factor Datasets Lab CANADA Laboratory
HDBP (halogenated dimethyl bipyrroles) 79 ± 3 % % fertile eggs in clutch Embryo 8 Avian Science and Conservation
Centre of McGill University
Toxicity Factor Datasets Lab CANADA Laboratory
MERCURY (elemental) See citation figures Egg concentration Embryo 4 different colonies along Sinaloa Coast Toxicity Factor Datasets MEXICO Laboratory
MERCURY (elemental) 0.98 ppm ± 0.23 Chick feathers Chick 21 Pamlico Sound, Island MN Toxicity Factor Datasets USA Laboratory
PERFLUOROOCTANOIC ACID <1 ng/g ww Liver concentration Not Reported 5 Cartagena Bay Toxicity Factor Datasets COLUMBIA Laboratory
HEXACHLOROCYCLOHEXANE 0.830 ng/g ww (0.486-1.30) Egg concentration 10 Marsh Island Toxicity Factor Datasets USA Laboratory
DDT (4,4'-) 16.51 ng/g ww ± 13.5 Egg concentration Embryo 8 Colorado River Delta Toxicity Factor Datasets MEXICO Laboratory
DDE (4,4'), SELENIUM COMPOUNDS 0.183 mm (0.175-0.187) Eggshell thickness Embryo 4 Carrizo Plain Toxicity Factor Datasets San Luis Obispo USA Laboratory
STRONTIUM 768 µg/g ± 500 Eggshell concentration Embryo 5 Lower San Pedro River Toxicity Factor Datasets USA Laboratory
DDE (4,4'-) 0.11 Egg concentration Embryo 22 South San Francisco Bay marshes Toxicity Factor Datasets USA Laboratory
COPPER (elemental) 55.90 µg/g dw Liver concentration NR Hatchling 4 Hamilton Harbour, Western Lake Ontario Toxicity Factor Datasets CANADA Laboratory
ORGANOCHLORINES 2900 ng/g ww Blubber concentration M Adult 11 Gulf of California Toxicity Factor Datasets MEXICO Laboratory
CARBOFURAN 29.90 mg/L LC50 NR Tadpole 6 Experimental Frog Farm, São Paulo Toxicity Factor Datasets Lab BRAZIL Laboratory
CHOLECALCIFEROL No effect Mean days to death B Not Reported 5 USDA National Wildlife Research Center, Fort Collins, CO Toxicity Factor Datasets Lab USA Laboratory
GLYPHOSATE 0.417 % mortality NR Tadpole 24 San Francisco State University Toxicity Factor Datasets Lab USA Laboratory
ENDOSULFAN No effect Hatching success NR Embryo 375 South Okanagan Valley, British Columbia Toxicity Factor Datasets CANADA Laboratory
GLYPHOSATE 1.7 [-0.4-1.9 (95 % CI)] LC10 NR Embryo 240 University of Pittsburgh Toxicity Factor Datasets Lab USA Laboratory
See citation Table 4; µg/g ww Total concentration in liver tissue Not Reported 23 Colusa National Wildlife Refuge (Colusa County); Natomas Basin (Sacramento County); Butte County, Glenn County; Yolo County Toxicity Factor Datasets USA Laboratory
MERCURY (elemental) 26.9 ± 5.5 ppb Blood concentration of live-captured 29 Pine Barrens Toxicity Factor Datasets USA Laboratory
CHROMIUM (elemental) 161 ± 46.0 ppb Skin concentration, dead-captured 20 Pine Barrens Toxicity Factor Datasets USA Laboratory
2,4,6-TRINITROTOLUENE 1038 mg/kg [332-2360 (95% CI)] LD50 F Adult 30 Toxicity Factor Datasets Lab USA Laboratory
2-AMINO-4,6-DINITROTOLUENE Increased Spleen weight M Adult 42 Toxicity Factor Datasets Lab USA Laboratory
PCB 0.6 Cracked eggs, multiple B Adult F0: 50 pairs University of Saskatchewan Toxicity Factor Datasets Lab CANADA Laboratory
PCB 0.36 Shortened limbs NR Hatchling NR University of Saskatchewan Toxicity Factor Datasets Lab CANADA Laboratory
PCB No effect Antebrachrium: growth rate F Nestling 33 pairs Avian Science and Conservation Centre of McGill
University
Toxicity Factor Datasets Lab CANADA Laboratory
PCB Earlier Body mass: maximal growth M Nestling 33 pairs Avian Science and Conservation Centre of McGill
University
Toxicity Factor Datasets Lab CANADA Laboratory
PBDE MIXTURE Increased Growth rate M Nestling 5 Toxicity Factor Datasets Lab CANADA Laboratory
HEXABROMOCYCLODODECANE (HBCDD) No effect Fledging success NR Fledgling 29 Toxicity Factor Datasets Lab CANADA Laboratory
PBDE MIXTURE Increased Plasma TT3 F Nestling Environment Canada Toxicity Factor Datasets Lab CANADA Laboratory
HYDROMORPHONE HYDROCHLORIDE 1.26 h Half-life (IM) B Adult 12 Toxicity Factor Datasets Lab USA Laboratory
PCB Weaker increase Corticosterone secretion from handling M Adult 18 Avian Science and Conservation Centre of McGill University Toxicity Factor Datasets Lab CANADA Laboratory
PBDE TECHNICAL MIXTURE, DE-71 Increased Gonadosomatic Index M Adult 21 Avian Science and
Conservation Centre at McGill University
Toxicity Factor Datasets Lab CANADA Laboratory
1,2-DIBROMO-4-(1,2-DIBROMOETHYL)CYCLOHEXANE (DBE-DBCH - FORMERLY TBECH) No effect Testes mass M Adult 46 pairs McGill University Toxicity Factor Datasets Lab CANADA Laboratory
PBDE TECHNICAL MIXTURE, DE-71 Decreased Hatching success Embryo 120 Toxicity Factor Datasets Lab Laboratory
AROCLOR 1242 Decreased Plasma thyroxine concentration F Adult 36 Toxicity Factor Datasets Lab Laboratory
PBDE TECHNICAL MIXTURE, DE-71 Increased Hepatic oxidative stress indicators Embryo 70 Patuxent Wildlife
Research Center
Toxicity Factor Datasets Lab Laboratory
PCB No effect Plasma T4 M Nestling 46 Avian Science and Conservation
Centre of McGill University
Toxicity Factor Datasets Lab CANADA Laboratory
PBDE TECHNICAL MIXTURE, DE-71 No effect Body weight F Adult 62 Toxicity Factor Datasets Lab CANADA Laboratory
HDBP (halogenated dimethyl bipyrroles) 15 ± 0.2 g Egg mass Embryo 7 Avian Science and Conservation
Centre of McGill University
Toxicity Factor Datasets Lab CANADA Laboratory
HDBP (halogenated dimethyl bipyrroles) 0.56 % eggs laid that resulted in banded juvenile kestrels Embryo Avian Science and Conservation
Centre of McGill University
Toxicity Factor Datasets Lab CANADA Laboratory
LEAD (elemental) See citation Liver concentration Not Reported 12 Toxicity Factor Datasets USA Laboratory
MERCURY (elemental) 1.19 ppm ± 0.42 Chick feathers Chick 22 Palmico Sound, Beacon Toxicity Factor Datasets USA Laboratory
PERFLUOROOCTANOIC ACID 1.1 ng/g ww (<1-2.2) Muscle concentration Not Reported 5 Cartagena Bay Toxicity Factor Datasets COLUMBIA Laboratory
PBDE MIXTURE 25.3 ng/g ww (10.2-69.8) Egg concentration 10 Marsh Island Toxicity Factor Datasets USA Laboratory
LINDANE 14.16 ng/g ww ± 8.8 Egg concentration Embryo 8 Colorado River Delta Toxicity Factor Datasets MEXICO Laboratory
DDE (4,4'-) 2.60 µg/g (0.90-10.11) Egg concentration Embryo 21 Lemoore Toxicity Factor Datasets Fresno USA Laboratory
CALCIUM 307 µg/g ± 12 Eggshell concentration Embryo 5 Lower San Pedro River Toxicity Factor Datasets USA Laboratory
PCB 1.3 Egg concentration Embryo 22 South San Francisco Bay marshes Toxicity Factor Datasets USA Laboratory
IRON (elemental) 295 µg/g dw Liver concentration NR Hatchling 4 Hamilton Harbour, Western Lake Ontario Toxicity Factor Datasets CANADA Laboratory
ORGANOCHLORINES 5000 ng/g lw Blubber concentration M Adult 11 Gulf of California Toxicity Factor Datasets MEXICO Laboratory
CYPERMETHRIN 0.460 ± 0.009 SE Mass NR Neonate 10 Oregon State University, Corvallis Toxicity Factor Datasets Lab USA Laboratory
GLYPHOSATE 0.625 % mortality NR Tadpole 24 San Francisco State University Toxicity Factor Datasets Lab USA Laboratory
ZINC SULFATE 844 [760-929 (95 % CI)] µg/L LC50 NR Tadpole 80 Colorado Division of Wildlife Aquatic Toxicity Laboratory, Ft. Collins, CO Toxicity Factor Datasets Lab USA Laboratory
GLYPHOSATE 2.0 [1.7-2.2 (95 % CI)] LC50 NR Embryo 240 University of Pittsburgh Toxicity Factor Datasets Lab USA Laboratory
LINDANE 153 ± 2.5 ng/g Accumulation in eggs from spiked nest material NR Embryo 10 Texas Tech University, Lubbock Toxicity Factor Datasets Lab USA Laboratory

Bullfrog (Lithobates catesbeianus formerly Rana catesbeiana)

Citation:
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Countries Lab
METHYLPARATHION 79.5 in loco heart rate Not Reported Tadpole 36 NR Toxicity Factor Datasets BRAZIL Laboratory
PENOXSULAM 7.52 mg/L LC50 Not Reported Tadpole 6 Experimental Frog Farm, São Paulo Toxicity Factor Datasets BRAZIL Laboratory

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