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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | 55-65 ppm | range of wet wt concentrations of Aroclor 1254 in adult carcasses | Both Male and Female | Adult | 22 pairs | mean(SE) of 4 samples: 26.3(0.2) ppm, wet wt, in diet | TOX-EXP IND - accumulation | at least one month | diet | Toxicity Factor Datasets |
AROCLOR 1254 | 29.5(1.4) ppm | mean(SE) wet wt concentrations of Aroclor 1254 in carcasses of 3 week old ducklings | Not Reported | Juvenile | 10 | mean(SE) of 4 samples: 26.3(0.2) ppm, wet wt, in diet | TOX-EXP IND - accumulation | at least one month | diet | Toxicity Factor Datasets |
AROCLOR 1254 | 23.3(1.0) ppm | mean(SE) wet wt concentrations of Aroclor 1254 in eggs | Not Reported | Embryo | 19 eggs | mean(SE) of 4 samples: 26.3(0.2) ppm, wet wt, in diet | TOX-EXP IND - accumulation | at least one month | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM | figure/table | figures and tables of selenium concentration over time (% of administered dose) | Female | Adult | Not Reported | 0.21-0.24 ug/kg bw | TOX-EXP IND - accumulation | single | intravenous | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | 33(7) ppm @ 10 ppm Se, 49(9) ppm @ 20 ppm Se, 87(11) ppm @ 40 ppm Se, 99(9) ppm in birds that died | mean (SE) dry wt concentrations of selenium in liver | Male | Adult | 10-25 | 0, 10, 20, 40, 80 ppm Se in diet, wet wt | TOX-EXP IND - accumulation | 16 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | 4.6 (0.18) ppm B @ 450 ppm B; 8.5 (0.34) ppm B @ 900 ppm B; 3.7 (0.16) ppm Se @ 3.5 ppm Se; 6.2 (0.27) ppm Se @ 7 ppm | mean (SE) wet wt concentrations of B and Se in liver | Both Male and Female | Adult | 14 pairs/treatment | 0, 450 ppm B, 900 ppm B, with 0, 3.5, or 7 ppm Se | TOX-EXP IND - accumulation | prior to and through reproduction (until ducklings were 14 d) | diet | Toxicity Factor Datasets |
BORIC ACID, SELENOMETHIONINE | 6.5 (0.25) ppm B @ 450 ppm B; 11 (0.4) ppm B @ 900 ppm B; 3.5 (0.10) ppm Se @ 3.5 ppm Se; 7.1 (0.28) ppm Se @ 7 ppm | mean (SE) wet wt concentrations of B and Se in egg | Both Male and Female | Both Adults and Juveniles | 14 pairs/treatment | 0, 450 ppm B, 900 ppm B, with 0, 3.5, or 7 ppm Se | TOX-EXP IND - accumulation | prior to and through reproduction (until ducklings were 14 d) | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | 4.6(0.66) ppm @ 103 ug/g Pb; 9.3(0.82) ppm @ 207 ug/g Pb; 12(1.3) ppm @ 414 ug/g Pb; 28(4.6) ppm @ 828 ug/g Pb | mean(SE) wet wt concentrations of lead in liver | Male | Adult | 10/ Pb treatment; 20/control treatment | 0, 1.5 (sediment control), 103, 207, 414, 828 ug/g calculated diet concentrations, added as contaminated sediment | TOX-EXP IND - accumulation | 10 wks | diet | Toxicity Factor Datasets |
LEAD COMPOUNDS | 3.0(0.30) ppm @ 642 ug/g Pb; 6.8(0.84) ppm @ 1284 ug/g Pb | mean (SE) wet wt Pb concentrations in blood | Male | Adult | 10/ Pb treatment; 5/control treatment | 0, 8.7 (sediment control), 642, 1284 ug/g diet, added as contaminated sediment | TOX-EXP IND - accumulation | 10 wks | diet | Toxicity Factor Datasets |
LEAD COMPOUNDS | 9.1(0.61) ppm @ 642 ug/g Pb; 16(1.5) ppm @ 1284 ug/g Pb | mean (SE) wet wt Pb concentrations in liver | Male | Adult | 10/ Pb treatment; 5/control treatment | 0, 8.7 (sediment control), 642, 1284 ug/g diet, added as contaminated sediment | TOX-EXP IND - accumulation | 10 wks | diet | Toxicity Factor Datasets |
LEAD COMPOUNDS | 4.1(1.03) ppm in blood, 13(1.2) ppm in liver @ 954 ug/g, complete diet; 4.0(0.58) ppm in blood, 38(6.5) ppm in liver @ 869 ug/g, corn diet | mean (SE) wet wt Pb concentrations in blood and liver | Male | Adult | 5/ Pb treatment;3/control treatments | 0, 3.0 (sediment control, complete diet), 3.7 (sediment control, corn diet), 954 (complete diet), 869 (corn diet) ug/g diet, added as contaminated sediment | TOX-EXP IND - accumulation | 15 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | higher in P8 than in T19 and TF, and in T19 than in TF | maximum likelihood estimate of 2-week Pb exposure rate | Both Male and Female | Both Adults and Juveniles | Sacramento National Wildlife Refuge; Willows, CA (39deg29'N, 122deg20'W) | 50 birds/treatment | 15750 (TF enclosure) , 173200 (T19 enclosure), or 2299700 (P8 enclosure) lead pellets/ha | TOX-EXP IND - accumulation | 4 mos | habitat contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | Equation: fecal Pb conc./fecal acid insoluble ash content = 61 + (1.06 x sediment Pb conc.) | relation between waterfowl fecal lead concentration (dry wt) and sediment lead concentration (dry wt) | Not Reported | Not Reported | Coeur d'Alene and St. Joe River Basins | 521 fecal analyses at 11 wetlands (at least 20 per wetland) | 0-5,000 mg/kg in sediments | TOX-EXP IND - accumulation | NR | contaminated sediment ingestion | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 250.6(39.0) ppm in femur, 78.3(9.7) ppm in liver, 256.3(22.2) in kidneys | mean(SE) dry wt lead concentrations in tissues of lead-dosed birds | Both Male and Female | Adult | 16/treatment | control, steel (eight #4 pellets), lead (eight #4 pellets), tungsten-iron (eight BB size pellets), tungsten-polymer (eight BB size pellets); See paper for data on shot recovery and erosion in dosed ducks. | TOX-EXP IND - accumulation | single exposure; 30 d observation | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | 9.2(0.52) ppm with seleno-D,L-methionine; 8.9(0.35) ppm with seleno-L-methionine; 6.6(0.37) ppm with selenized yeast | mean(SE) wet wt concentrations of selenium in 8th egg laid | Female | Adult | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-EXP IND - accumulation | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 7.6(0.26) ppm, egg, 6.0(0.31) ppm, fem. liver, 9.6(0.95) ppm, male liver @ 10 ppm Se; 9.3(0.85) ppm, egg, 9.2(1.61) ppm, female liver, 114(25.3) ppm, male liver @ 10 ppm Se + 10 ppm Hg | mean(SE) wet wt concentration of Se in egg and liver of treated birds | Both Male and Female | Adult | 12/group | 0, 10 ppm Hg, 10 ppm Se, 10 ppm Hg plus 10 ppm Se in diet | TOX-EXP IND - accumulation | April 1-June 16 | diet | Toxicity Factor Datasets |
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 16(0.8) ppm, egg, 22(1.5) ppm, fem. liver, 71(8.9) ppm, male liver @ 10 ppm Hg; 17(0.6) ppm, egg, 21(4.3) ppm, female liver, 65(4.1) ppm, male liver @ 10 ppm Se + 10 ppm Hg | mean(SE) wet wt concentration of Hg in egg and liver of treated birds | Both Male and Female | Adult | 12/group | 0, 10 ppm Hg, 10 ppm Se, 10 ppm Hg plus 10 ppm Se in diet | TOX-EXP IND - accumulation | April 1-June 16 | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 3.4(0.22) ppm @ 10 ppm Se; 5.2(0.44) ppm @ 10 ppm Hg + 10 ppm Se | mean (SE) wet wt Se concentrations in brain | Male | Adult | 12/treatment | 0, 10 ppm Hg, 10 ppm Se, 10 ppm Hg plus 10 ppm Se in diet | TOX-EXP IND - accumulation | April 1-June 16 | diet | Toxicity Factor Datasets |
METHYLMERCURY CHLORIDE, SELENOMETHIONINE | 17.9(1.06) ppm @ 10 ppm Hg; 14.1(0.74) ppm @ 10 ppm Hg + 10 ppm Se | mean (SE) wet wt Hg concentrations in brain | Male | Adult | 12/treatment | 0, 10 ppm Hg, 10 ppm Se, 10 ppm Hg plus 10 ppm Se in diet | TOX-EXP IND - accumulation | April 1-June 16 | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS | 6.86(0.99) ppm, kidneys; 2.23(0.492) ppm, liver; 0.468(0.277) ppm, gonads | mean(SE) wet wt Bi concentration in organs of Bi-treated birds | Both Male and Female | Adult | 20 males, 20 females per group | 0, six #4 iron or bismuth shot; see paper for retention and dissolution of shot in gizzards of treated birds | TOX-EXP IND - accumulation | 30 d | oral gavage | Toxicity Factor Datasets |
BISMUTH COMPOUNDS, IRON COMPOUNDS | 145(6.0) ppm, kidneys; 1086(72) ppm, liver; 32.1(6.3) ppm, gonads | mean(SE) wet wt Fe concentration in organs of Fe-treated birds | Both Male and Female | Adult | 20 males, 20 females per group | 0, six #4 iron or bismuth shot; see paper for retention and dissolution of shot in gizzards of treated birds | TOX-EXP IND - accumulation | 30 d | oral gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | 213(27.1) ppm, kidney; 91(4.55) ppm, liver; 9.8(3.22) ppm, ovary; 3.49(0.61) ppm, testis | mean(SE) wet wt concentrations of Pb in Pb-dosed birds | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | 0, eight #4 iron, bismuth, or lead shot, administered on Days 1, 30, 60, 90; see paper for dissolution and retention of shot in gizzards of treated birds | TOX-EXP IND - accumulation | up to 150 d | oral gavage | Toxicity Factor Datasets |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | 237(17.2) ppm, kidney; 1936(233) ppm, liver; 90.6(6.85) ppm, ovary; 13.1(1.29) ppm, testis | mean(SE) wet wt concentrations of Fe in Fe-dosed birds | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | 0, eight #4 iron, bismuth, or lead shot, administered on Days 1, 30, 60, 90; see paper for dissolution and retention of shot in gizzards of treated birds | TOX-EXP IND - accumulation | up to 150 d | oral gavage | Toxicity Factor Datasets |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | 1.54(0.280) ppm, kidney; 0.637(0.134) ppm, liver; 0.042(0.007) ppm, ovary; 0.098(0.042) ppm, testis | mean(SE) wet wt concentrations of Bi in Bi-dosed birds | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | 0, eight #4 iron, bismuth, or lead shot, administered on Days 1, 30, 60, 90; see paper for dissolution and retention of shot in gizzards of treated birds | TOX-EXP IND - accumulation | up to 150 d | oral gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased | blood Pb concentrations versus pre-dose controls | Both Male and Female | Adult | laboratory | 20 per sex | 1 lead shot (no. 4) | TOX-EXP IND - accumulation | single exposure | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | increased (12-fold) | selenium concentrations in pectoral muscle | Male | Adult | Laboratory | Controls = 24 Treated = 8 | 0, 2.2 mg Se/L | TOX-EXP IND - accumulation | 12 weeks | Drinking water | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased @ all doses | Pb concentrations in wing bone and liver | Both Male and Female | Not Reported | 5-6/group | 0, 2, 5, 5 (w/5 repeated doses) Pb shot (no. 6) | TOX-EXP IND - accumulation | Single dose, except for repeated dose group | Gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | liver: C = 7.4(1-e^-0.382t) muscle: C = 8.0(1-e^-0.037t) | selenium accumulation equations | Both Male and Female | Adult | 3 | 10 ppm Se | TOX-EXP IND - accumulation | 42 days | Diet | Toxicity Factor Datasets |
SELENOMETHIONINE | liver: C = 7.4e^-0.037t muscle: C = 5.6e^-0.023t liver at peak body burden: C = 22.6e^-0.246t + 2.5 e^-0.008t muscle at peak body burden: C = 6.4e^-0.029t Loss phase for blood at peak body burden: C = 12.0e^-0.071t | selenium depuration equations | Both Male and Female | Adult | 3 | 10 ppm, doubled weekly, Se | TOX-EXP IND - accumulation | 28 days | Diet | Toxicity Factor Datasets |
SELENOMETHIONINE | liver: 18.7 d muscle: 30.1 d | half life of selenium in tissues | Both Male and Female | Adult | 3 | 10 ppm Se | TOX-EXP IND - accumulation | 42 days | Diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIELDRIN | increased with all doses | brain, liver, and adipose dieldrin concentrations | Both Male and Female | Juvenile | 4-6 per group | 0, 4, 10, and 30 ppm Dieldrin | TOX-EXP IND - accumulation | Second - generation. Exposed 75 days after hatch. | Diet | Toxicity Factor Datasets |
Endpoint Value | Endpoint Description | Toxicity Endpoint Type | Type |
---|---|---|---|
0.99(0.050) ppm @ 103 ug/g Pb; 1.7(0.18) ppm @ 207 ug/g Pb; 2.9(0.27) ppm @ 414 ug/g Pb; 6.1(0.97) ppm @ 828 ug/g Pb | mean(SE) wet wt concentrations of lead in blood at 10 wks post-dose | TOX-EXP IND - accumulation | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | blood Se concentration = 1.307 + 0.852(diet Se concentration) | relation between Se concentrations in blood (dry wt) and diet (dry wt) | Male | Adult | 40 birds | 0,6, 12 ppm, dry wt, Se in diet | TOX-EXP IND - accumulation | 11 wks | diet | Toxicity Factor Datasets |
SELENOMETHIONINE | egg Se concentration = 1.307 + 0.852(diet Se concentration) | relation between Se concentrations in egg (dry wt) and diet (dry wt) | Female | Adult | 53 eggs | 0,6, 12 ppm, dry wt, Se in diet | TOX-EXP IND - accumulation | 11 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
LINDANE | 153 ± 2.5 ng/g | Accumulation in eggs from spiked nest material | NR | Embryo | Texas Tech University, Lubbock | 10 | 842 ± 169 ng/g | TOX-EXP IND - accumulation | 6 w | Spiked nest material | Toxicity Factor Datasets |
HEPTACHLOR | 2.3 ± 2.0 ng/g | Accumulation in eggs from spiked nest material | NR | Embryo | Texas Tech University, Lubbock | 10 | 726 ± 114 ng/g | TOX-EXP IND - accumulation | 6 w | Spiked nest material | Toxicity Factor Datasets |
ALDRIN | 5.5 ± 6.6 ng/g | Accumulation in eggs from spiked nest material | NR | Embryo | Texas Tech University, Lubbock | 10 | 635 ± 94 ng/g | TOX-EXP IND - accumulation | 6 w | Spiked nest material | Toxicity Factor Datasets |
DIELDRIN | 8.9 ± 2.9 ng/g | Accumulation in eggs from spiked nest material | NR | Embryo | Texas Tech University, Lubbock | 10 | 2266 ± 352 ng/g | TOX-EXP IND - accumulation | 6 w | Spiked nest material | Toxicity Factor Datasets |
ENDRIN | 25 ± 16 ng/g | Accumulation in eggs from spiked nest material | NR | Embryo | Texas Tech University, Lubbock | 10 | 2382 ± 365 ng/g | TOX-EXP IND - accumulation | 6 w | Spiked nest material | Toxicity Factor Datasets |
DDT (4,4'-) | Not detected | Accumulation in eggs from spiked nest material | NR | Embryo | Texas Tech University, Lubbock | 10 | 2201 ± 511 ng/g | TOX-EXP IND - accumulation | 6 w | Spiked nest material | Toxicity Factor Datasets |