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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 639.43 and 345.95 ug/g, dry wt | lead concentration in kidneys of treated birds | Not Reported | Not Reported | 2 | four #8 lead shots | TOX-EXP IND - accumulation | single | oral | Toxicity Factor Datasets |
LEAD (elemental) | 58.35 and 214.71 ug/g, dry wt | lead concentrations in livers of dosed birds | Not Reported | Not Reported | 2 | four #8 lead shots | TOX-EXP IND - accumulation | single | oral | Toxicity Factor Datasets |
LEAD (elemental) | light to moderate lesions | histological exam for hemosiderin loading in liver | Not Reported | Not Reported | 2 | four #8 lead shots | TOX-Non-Repro-Sublethal - organ/system effects | single | oral | Toxicity Factor Datasets |
LEAD (elemental) | high degree of lesions present | histological exam of acid-fast intranuclear inclusions of cells of kidney proximal convoluted tubules | Not Reported | Not Reported | 1 | four #8 lead shots | TOX-Non-Repro-Sublethal - organ/system effects | single | oral | Toxicity Factor Datasets |
LEAD (elemental) | high degree of lesions present | histological exam for hemosiderin loading in liver | Not Reported | Not Reported | 1 | four #8 lead shots | TOX-Non-Repro-Sublethal - organ/system effects | single | oral | Toxicity Factor Datasets |
LEAD (elemental) | 1,297.57 ug/g, dry wt | lead concentration in kidneys | Not Reported | Not Reported | 1 | four #8 lead shots | TOX-EXP IND - accumulation | single | oral | Toxicity Factor Datasets |
LEAD (elemental) | 178.81 ug/g, dry wt | lead concentration in liver | Not Reported | Not Reported | 1 | four #8 lead shots | TOX-EXP IND - accumulation | single | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased at 1, 4 shots | mortality | Both Male and Female | Adult | 10 birds/dose | 0, 1, 2, or 4 #8 lead shots | TOX-MORT - dose-response data | single | oral | Toxicity Factor Datasets |
LEAD (elemental) | increased at all doses | lead concentrations in blood | Both Male and Female | Adult | 10 birds/dose | 0, 1, 2, or 4 #8 lead shots | TOX-EXP IND - accumulation | single | oral | Toxicity Factor Datasets |
LEAD (elemental) | decreased at all doses | delta-aminolevulinic acid dehydratase (ALAD)activity in blood | Both Male and Female | Adult | 10 birds/dose | 0, 1, 2, or 4 #8 lead shots | TOX-EXP IND - biomarkers | single | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | increased at 10 ppm | interval from nest occupation to egg-laying | Female | Adult | 10-13/group | 0, or 10 ppm in diet | TOX-REPRO - behavior | 28 d | diet | Toxicity Factor Datasets |
AROCLOR 1254 | decreased at 10 ppm | percent of birds that laid eggs | Female | Adult | 10-13/group | 0, or 10 ppm in diet | TOX-REPRO - physiology | 28 d | diet | Toxicity Factor Datasets |
AROCLOR 1254 | no effect | progesterone concentration in blood | Female | Adult | 10-13/group | 0, or 10 ppm in diet | TOX-REPRO - physiology | 28 d | diet | Toxicity Factor Datasets |
AROCLOR 1254 | earlier @ 10 ppm | timing of peak progesterone concentration in blood | Female | Adult | 10-13/group | 0, or 10 ppm in diet | TOX-REPRO - physiology | 28 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | increased at 10, 40 ppm | length of courtship period | Both Male and Female | Adult | 8/group | 0, 10, 40 ppm in diet | TOX-REPRO - behavior | 42 d | diet | Toxicity Factor Datasets |
AROCLOR 1254 | decreased at 40 ppm | courtship behavior score (intensity) | Both Male and Female | Adult | 8/group | 0, 10, 40 ppm in diet | TOX-REPRO - behavior | 42 d | diet | Toxicity Factor Datasets |
AROCLOR 1254 | decreased at 10, 40 ppm | number of pairs nesting | Both Male and Female | Adult | 8/group | 0, 10, 40 ppm in diet | TOX-REPRO - behavior | 42 d | diet | Toxicity Factor Datasets |
AROCLOR 1254 | delayed at 10 ppm | onset of nest initiation | Both Male and Female | Adult | 8/group | 0, 10, 40 ppm in diet | TOX-REPRO - behavior | 42 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | no effect | metabolic rate at a range of ambient temperatures | Male | Adult | 4/group | 0 or 40 ppm in diet | TOX-Non-Repro-Sublethal - whole animal | 42 d | diet | Toxicity Factor Datasets |
AROCLOR 1254 | no effect | body weight | Male | Adult | 10/group | 0 or 40 ppm in diet | TOX-Non-Repro-Sublethal - whole animal | 42 d | diet | Toxicity Factor Datasets |
AROCLOR 1254 | decreased at 40 ppm | body temperature at a range of ambient temperatures | Male | Adult | 4/group | 0 or 40 ppm in diet | TOX-Non-Repro-Sublethal - whole animal | 42 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
METHIOCARB | decreased at 1,000 ppm | body weight | Not Reported | Not Reported | 6/group | 0, 100, 316, or 1,000 ppm in diet | TOX-Non-Repro-Sublethal - whole animal | 30 d | diet | Toxicity Factor Datasets |
METHIOCARB | decreased at all doses | food consumption | Not Reported | Not Reported | 6/group | 0, 100, 316, or 1,000 ppm in diet | TOX-Non-Repro-Sublethal - behavioral effects | 30 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AMINOPYRIDINE (4-) | 150 ppm | dose at which 50% mortality was observed | Not Reported | Adult | 7/group | 150, 300, 600, 1,000 ppm 4-aminopyridine in corn bait | TOX-MORT - dose-response data | 7 d | diet | Toxicity Factor Datasets |
AMINOPYRIDINE (4-) | 316 ppm | dietary LC50 | Not Reported | Adult | 6/group | 0, 31.6, 100, 316 ppm 4-aminopyridine in diet | TOX-MORT - dose-response data | 30 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Units | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
ALDICARB | 0.82 | LD50 | mg/kg bw | Not Reported | Adult | 50 birds total | 0.66, 0.74, 0.82, 0.90, 1.02, 1.10, 1.22, 1.40 mg/kg bw | TOX-MORT - toxicity benchmarks | single | oral | Toxicity Factor Datasets |
ALDICARB | no effect | daily survival rate in dosed wild birds | Not Reported | Adult | 9-12/group | 0, 0.48, 0.55, 0.83 mg/kg bw | TOX-MORT - mortality in the field | single | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
PICLORAM, TRICLOPYR | no effect | nesting success in treated plots | Both Male and Female | Adult | Rob and Bessie Welder Wildlife Refuge | Not Reported | 38 l/ha application | TOX-Non-Repro-Sublethal - indirect effects | NR | field application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | no effect | Not Reported | Embryo | Patuxent Research Refuge | 2 eggs | 1 lb/gal DDT application to nest applied at 0.4 ml/ft^2 | TOX-REPRO - reproductive success | single | egg surface | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
FLUORIDE, SODIUM | 247.0 +/- 103.1 ppm @ 0 ppm; 6137.9 +/- 823.8 ppm @ 1120 ppm; 10,272.6 +/- 865.8 ppm @ 2240 ppm | mean fluoride content in the diaphyses of femurae | Both Male and Female | Juvenile | 9-10/group | 0, 1120, 2240 ppm fluoride | TOX-EXP IND - accumulation | 20 d | diet | Toxicity Factor Datasets |
FLUORIDE, SODIUM | no effect | growth of body weight and skeletal components (skull, bill, tarsus, antebrachium, and manus) | Both Male and Female | Juvenile | 9-10/group | 0, 1120, 2240 ppm fluoride | TOX-REPRO - development | 20 d | diet | Toxicity Factor Datasets |
FLUORIDE, SODIUM | increased at 1120, 2240 ppm | % bone ash | Both Male and Female | Juvenile | 9-10/group | 0, 1120, 2240 ppm fluoride | TOX-REPRO - development | 20 d | diet | Toxicity Factor Datasets |
FLUORIDE, SODIUM | decreased at 2240 ppm | bonebreaking strength | Both Male and Female | Juvenile | 9-10/group | 0, 1120, 2240 ppm fluoride | TOX-REPRO - development | 20 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) | increased with PCB 153 | aminopyrine N-demethylase and aldrin epoxidase activities in liver | Female | Adult | 5-6/group | 0, 4 mg/kg/d PCB 153, 3 mg/kg/d PCB 105, or 0.05 mg/kg/d PCB 126; 3 x's/wk | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 4 wk | oral | Toxicity Factor Datasets |
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) | increased with PCB 105 | aminopyrine N-demethylase activity in liver | Female | Adult | 5-6/group | 0, 4 mg/kg/d PCB 153, 3 mg/kg/d PCB 105, or 0.05 mg/kg/d PCB 126; 3 x's/wk | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 4 wk | oral | Toxicity Factor Datasets |
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) | increased with PCB 126 | 7-ethoxyresorufin O-deethylase and aldrin epoxidase activities in liver | Female | Adult | 5-6/group | 0, 4 mg/kg/d PCB 153, 3 mg/kg/d PCB 105, or 0.05 mg/kg/d PCB 126; 3 x's/wk | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 4 wk | oral | Toxicity Factor Datasets |
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) | no effect | hepatic porphyrin levels | Female | Adult | 5-6/group | 0, 4 mg/kg/d PCB 153, 3 mg/kg/d PCB 105, or 0.05 mg/kg/d PCB 126; 3 x's/wk | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 4 wk | oral | Toxicity Factor Datasets |
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) | no effect | liver weight | Female | Adult | 5-6/group | 0, 4 mg/kg/d PCB 153, 3 mg/kg/d PCB 105, or 0.05 mg/kg/d PCB 126; 3 x's/wk | TOX-Non-Repro-Sublethal - organ/system effects | 4 wk | oral | Toxicity Factor Datasets |
PCB 105 (2,3,3',4,4'-PENTACHLOROBIPHENYL), PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL) | 2.4 (control), 119.0 (PCB 153), 182.0 (PCB 105), 3.3 (PCB 126) mg/kg, wet weight | PCB concentrations in pooled adipose tissue | Female | Adult | 5-6/group | 0, 4 mg/kg/d PCB 153, 3 mg/kg/d PCB 105, or 0.05 mg/kg/d PCB 126; 3 x's/wk | TOX-EXP IND - accumulation | 4 wk | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | 21.5-22.6% decrease @ 33 ppm | sperm concentration | Male | Adult | 10/group | 0 and 33 ppm, wet weight (=9-10 mg/kg bw/d) | TOX-REPRO - physiology | 62 and 69 d (2 study periods) | diet | Toxicity Factor Datasets |