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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
RADIONUCLIDES | see citation | table of mean concentrations of 6 radionuclides (238Pu, 239Pu, 241Am, 242Cm, 244Cm, 90Sr) in 6 mallard tissue types | Not Reported | Adult | leaching ponds, Test Reactor Area, Idaho National Engineering Laboratory | 7-15 | see citation for table radionuclide concentrations in water, plankton, periphyton, sediment | TOX-EXP IND - accumulation | 43-145 d | site contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 5.7 ppm (whole blood); 6.2 ppm (liver); 2.4 ppm (spleen) @ 300 mg/kg body weight | lead concentrations in tissues, 96 hr after exposure to lead in ducklings receiving vitamin E | Not Reported | Juvenile | 5/dose | control, 300 mg/kg body weight; elemental lead packaged in gelatin capsules | TOX-EXP IND - accumulation | single | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | increase @ 15, 30 ppm | plasma and liver GSH-peroxidase activity (for all Se forms), compared to controls | Not Reported | Juvenile | 10/dose | control, 15, 30 ppm Se as seleno-D,L-methionine, seleno-L-methionine or selenized yeast | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 2 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 10.3(0.7) ppm in femur, 14.1(0.6) ppm in liver, 6.8(0.2) in kidneys | mean(SE) dry wt tungsten concentrations in tissues of tungsten-iron-dosed birds | Both Male and Female | Adult | 16/treatment | control, steel (eight #4 pellets), lead (eight #4 pellets), tungsten-iron (eight BB size pellets), tungsten-polymer (eight BB size pellets); See paper for data on shot recovery and erosion in dosed ducks. | TOX-EXP IND - accumulation | single exposure; 30 d observation | oral | Toxicity Factor Datasets |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 4.3(0.7) ppm in femur, non-detect. in liver, 2.4(0.2) in kidneys | mean(SE) dry wt tungsten concentrations in tissues of tungsten-polymer-dosed birds | Both Male and Female | Adult | 16/treatment | control, steel (eight #4 pellets), lead (eight #4 pellets), tungsten-iron (eight BB size pellets), tungsten-polymer (eight BB size pellets); See paper for data on shot recovery and erosion in dosed ducks. | TOX-EXP IND - accumulation | single exposure; 30 d observation | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean survival times compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | five #4 pellets of lead, iron, or bismuth/tin embedded in breast muscle | TOX-MORT - dose-response data | 185 and 365 d | embedded in muscle | Toxicity Factor Datasets |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean body weight and organ weights compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | five #4 pellets of lead, iron, or bismuth/tin embedded in breast muscle | TOX-Non-Repro-Sublethal - whole animal | 185 and 365 d | embedded in muscle | Toxicity Factor Datasets |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean hematocrit values compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | five #4 pellets of lead, iron, or bismuth/tin embedded in breast muscle | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 185 and 365 d | embedded in muscle | Toxicity Factor Datasets |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | 130(10.1) ppm in kidneys, 0.19(0.06) ppm in liver | mean(SE) wet wt concentration of bismuth in organs | Both Male and Female | Adult | 5 males, 5 females per group | five #4 pellets of lead, iron, or bismuth/tin embedded in breast muscle | TOX-EXP IND - accumulation | 185 and 365 d | embedded in muscle | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | no effect | incidence of illness versus controls | Both Male and Female | Adult | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-Non-Repro-Sublethal - whole animal | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS, SELENOMETHIONINE | no effect | egg fertility, egg weight, eggshell thickness, and mean interval between laying of eggs versus controls | Both Male and Female | Adult | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-REPRO - physiology | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-L-methionine or seleno-D,L-methionine | hatchability versus controls | Both Male and Female | Both Adults and Juveniles | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-REPRO - reproductive success | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-L-methionine | duckling survival compared to controls | Both Male and Female | Adult | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-REPRO - reproductive success | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-D,L-methionine, seleno-L-methionine, or selenized yeast | number of 6-day-old ducklings produced per female versus controls | Both Male and Female | Both Adults and Juveniles | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-REPRO - reproductive success | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | significant effect | PCB treatment altered the shape of the body weight growth curve but not the asymptotic weight | Both Male and Female | Juvenile | 15/dose | 0, 0.5, 5.0, 50 mg/kg diet | TOX-Non-Repro-Sublethal - whole animal | 12 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1242 | no effect @ 150 ppm | mortality during experiment | Both Male and Female | Adult | 12 pairs/dose | 0, 150 mg/kg diet | TOX-MORT - dose-response data | 12 wks | diet | Toxicity Factor Datasets |
AROCLOR 1242 | decrease @ 150 ppm | body weight at 6, 8 and 12 wks of treatment | Female | Adult | 12 pairs/dose | 0, 150 mg/kg diet | TOX-Non-Repro-Sublethal - whole animal | 12 wks | diet | Toxicity Factor Datasets |
AROCLOR 1242 | no effect @ 150 ppm | embryo mortality, # infertile eggs/clutch or # eggs hatched/clutch | Female | Adult | 12 pairs/dose | 0, 150 mg/kg diet | TOX-REPRO - reproductive success | 12 wks | diet | Toxicity Factor Datasets |
AROCLOR 1242 | 8.9% decrease @ 150 ppm | eggshell thickness, compared to control | Female | Adult | 12 pairs/dose | 0, 150 mg/kg diet | TOX-REPRO - physiology | 12 wks | diet | Toxicity Factor Datasets |
AROCLOR 1242 | 105.0 (7.7 SE) mg Aroclor 1260/kg egg @ 150 ppm | PCB concentration in eggs (PCB resembled Aroclor 1260 profile most closely) | Female | Adult | 12 pairs/dose | 0, 150 mg/kg diet | TOX-EXP IND - accumulation | 12 wks | diet | Toxicity Factor Datasets |
AROCLOR 1242 | no effect @ 150 ppm | weight and survival of offspring (exposed in ovo) fed control diet after hatching for 3 wks | Female | Adult | 12 pairs/dose | 0, 150 mg/kg diet | TOX-REPRO - development | 12 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | body weight at end of experiment | Not Reported | Juvenile | 12/dose | 0, 0.014, 0.052, 0.118 mg/L | TOX-Non-Repro-Sublethal - whole animal | 34 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | no effect | no mortality observed | Not Reported | Juvenile | 12/dose | 0, 0.014, 0.052, 0.118 mg/L | TOX-MORT - dose-response data | 34 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 706 - 1,995 | steady state bioconcentration factor for lipid, calculated on a wet weight basis; range for 7 doses | Not Reported | Juvenile | 8-16/dose | 0, 0.014, 0.019, 0.052, 0.075, 0.118, 0.177, 0.193 mg/L | TOX-EXP IND - accumulation | 8-34 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 178 - 684 | steady state bioconcentration factor for skin, calculated on a wet weight basis; range for 7 doses | Not Reported | Juvenile | 8-16/dose | 0, 0.014, 0.019, 0.052, 0.075, 0.118, 0.177, 0.193 mg/L | TOX-EXP IND - accumulation | 8-34 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 49 - 163 | steady state bioconcentration factor for liver, calculated on a wet weight basis; range for 7 doses | Not Reported | Juvenile | 8-16/dose | 0, 0.014, 0.019, 0.052, 0.075, 0.118, 0.177, 0.193 mg/L | TOX-EXP IND - accumulation | 8-34 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 5.5 - 95 | steady state bioconcentration factor for muscle, calculated on a wet weight basis; range for 7 doses | Not Reported | Juvenile | 8-16/dose | 0, 0.014, 0.019, 0.052, 0.075, 0.118, 0.177, 0.193 mg/L | TOX-EXP IND - accumulation | 8-34 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 165 ug/g diet (100 - 224 ug/g, 95% CI) | 96 hr LC50 | Not Reported | Juvenile | 10/dose | 0, 0.3, 16, 48, 155, 272, 606 ug/g diet | TOX-MORT - toxicity benchmarks | 24 d | diet | Toxicity Factor Datasets |
DIELDRIN | 29.5 ug/g diet (14 - 28 ug/g, 95% CI) | 24-d LC50 | Not Reported | Juvenile | 10/dose | 0, 0.3, 16, 48, 155, 272, 606 ug/g diet | TOX-MORT - toxicity benchmarks | 24 d | diet | Toxicity Factor Datasets |
DIELDRIN | 16.4 ug/g diet | 24-d LOAEL based on growth impairment | Not Reported | Juvenile | 10/dose | 0, 0.3, 16, 48, 155, 272, 606 ug/g diet | TOX-Non-Repro-Sublethal - whole animal | 24 d | diet | Toxicity Factor Datasets |
DIELDRIN | 0.3 ug/g | 24-d NOAEL based on growth impairment | Not Reported | Juvenile | 10/dose | 0, 0.3, 16, 48, 155, 272, 606 ug/g diet | TOX-Non-Repro-Sublethal - whole animal | 24 d | diet | Toxicity Factor Datasets |
DIELDRIN | see citation | figures of tissue dieldrin concentrations at different exposure times and doses | Not Reported | Juvenile | 10/dose | 0, 0.3, 16, 48, 155, 272, 606 ug/g diet | TOX-EXP IND - accumulation | 24 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DICOFOL | increase @ 100 ug/g | incidence of cracked and soft shelled eggs | Female | Adult | 4-8/dose | 0, 3, 10, 30, 100 ug/g diet | TOX-REPRO - physiology | 42 d | diet | Toxicity Factor Datasets |
DICOFOL | no effect | egg production during study period | Female | Adult | 4-8/dose | 0, 3, 10, 30, 100 ug/g diet | TOX-REPRO - physiology | 42 d | diet | Toxicity Factor Datasets |
DICOFOL | no effect | body weight at end of study | Female | Adult | 4-8/dose | 0, 3, 10, 30, 100 ug/g diet | TOX-Non-Repro-Sublethal - whole animal | 42 d | diet | Toxicity Factor Datasets |
DICOFOL | no effect | mean daily food consumption rate (169.8 g food/kg body weight) | Female | Adult | 4-8/dose | 0, 3, 10, 30, 100 ug/g diet | TOX-Non-Repro-Sublethal - behavioral effects | 42 d | diet | Toxicity Factor Datasets |
DICOFOL | 2-12% decrease @ 10-100 ug/g | eggshell thickness, compared to controls | Female | Adult | 4-8/dose | 0, 3, 10, 30, 100 ug/g diet | TOX-REPRO - physiology | 42 d | diet | Toxicity Factor Datasets |
DICOFOL | 5.4 (0.3 SE) ug/g wet wt. @ 3 ug/g diet; 18.1 (1.2 SE) @ 10 ug/g diet; 37.1 (1.6 SE) @ 30 ug/g diet; 150.7 (9.9SE) @ 100 ug/g diet, | mean egg yolk concentrations of p,p'-dicofol after 37-42 d on dicofol diet | Female | Adult | 4-8/dose | 0, 3, 10, 30, 100 ug/g diet | TOX-EXP IND - accumulation | 42 d | diet | Toxicity Factor Datasets |
DICOFOL | ST = 1.020 - 0.056C | regression equation relating shell thickness (mm) to log10 yolk concentration (C, ug/g); r2=0.39 | Female | Adult | 100 | 0, 3, 10, 30, 100 ug/g diet | TOX-REPRO - physiology | 42 d | diet | Toxicity Factor Datasets |
DDE (4,4'-) | no effect | egg production during study period | Female | Adult | 5-10/dose | 0, 3, 30, 100 ug/g diet | TOX-REPRO - physiology | 42 d | diet | Toxicity Factor Datasets |