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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
BORIC ACID, SELENOMETHIONINE | increased @ 15 ppm Se (with and w/out B), 1000 ppm B | incidence of plasma chemistry changes versus controls | Not Reported | Juvenile | 15 birds/group | 0, 15 ppm Se, 60 ppm Se, 1000 ppm B, 15 ppm Se + 1000 ppm B, 60 ppm Se + 1000 ppm B (all treatments were conducted with 7% protein in the diet) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 4 wks | diet | Toxicity Factor Datasets |
BORIC ACID, SELENOMETHIONINE | decreased @ 1000 ppm B | hematocrits and hemoglobin concentrations versus controls | Not Reported | Juvenile | 15 birds/group | 0, 15 ppm Se, 60 ppm Se, 1000 ppm Bo, 15 ppm Se + 1000 ppm Bo, 60 ppm Se + 1000 ppm Bo (all treatments were conducted with 22% protein in the diet) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 4 wks | diet | Toxicity Factor Datasets |
BORIC ACID, SELENOMETHIONINE | decreased @ 15 ppm Se (with or w/out B), and 1000 ppm B | hematocrits and hemoglobin concentrations versus controls | Not Reported | Juvenile | 15 birds/group | 0, 15 ppm Se, 60 ppm Se, 1000 ppm B, 15 ppm Se + 1000 ppm B, 60 ppm Se + 1000 ppm B (all treatments were conducted with 7% protein in the diet) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 4 wks | diet | Toxicity Factor Datasets |
BORIC ACID, SELENOMETHIONINE | 10.8 (@ 15 ppm Se), 56.0 (@ 60 ppm) ppm Se, wet wt 11.0 (@ 1000 ppm B) ppm B, wet wt | geometric mean Se and B concentrations in liver | Not Reported | Juvenile | 15 birds/group | 0, 15 ppm Se, 60 ppm Se, 1000 ppm B, 15 ppm Se + 1000 ppm B, 60 ppm Se + 1000 ppm B (all treatments were conducted with 22% protein in the diet) | TOX-EXP IND - accumulation | 4 wks | diet | Toxicity Factor Datasets |
BORIC ACID, SELENOMETHIONINE | 22.5 (@ 15 ppm Se w/out B), 41.9 (@ 15 ppm Se w/B) ppm Se, wet wt 13.0 (@ 1000 ppm B) ppm B, wet wt | geometric mean Se and B concentrations in liver | Not Reported | Juvenile | 15 birds/group | 0, 15 ppm Se, 60 ppm Se, 1000 ppm B, 15 ppm Se + 1000 ppm B, 60 ppm Se + 1000 ppm B (all treatments were conducted with 7% protein in the diet) | TOX-EXP IND - accumulation | 4 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
MONOCROTOPHOS | 5.86 (4.70-7.29), 7.21 (5.79-8.98), 5.10 (4.44-5.86), 3.36 (2.77-4.09) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
PROPOXUR | 7.38 (5.97-9.14), 12.7 (10.2-15.9), 14.6 (12.4-17.4), 9.58 (7.61-12.1) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
DICROTOPHOS | 6.17 (3.33-11.4), 7.03 (5.30-9.31), 6.73 (5.53-8.19), 4.14 (3.33-5.16) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
FENSULFOTHION | 0.528, 0.747, 1.06 (0.868-1.29), 0.747 (0.588-0.949) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
ENDRIN | 22.3 (9.88-50.3), 3.37 (2.36-4.80), 2.90 (2.17-3.88), 5.33 (3.67-7.73) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
CARBOFURAN | 0.370 (0.283-0.484), 0.628 (0.530-0.744), 0.510 (0.410-0.635), 0.415 (0.333-0.516) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
DEMETON | 13.3 (11.0-16.2), 15.3 (12.9-18.1), 15.1 (12.0-19.0), 8.19 (6.58-10.2) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
TOXAPHENE (POLYCHLORINATED CAMPHENES) | 130 (80.4-210), 30.8 (23.3-40.6), 70.7 (37.6-133) | LD50's determined at ages 36 hr, 7 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
MEXACARBATE | 3.16 (2.17-4.61), 4.11 (2.70-6.26), 3.61 (2.37-5.49), 3.23 (2.72-3.85), 2.72(2.28-3.23) | LD50's determined at ages 48 hr, 7 d, 14 d, 30 d and 60 d, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
SODIUM MONOFLUOROACETATE | 9.78 (6.31-15.2), 3.71 (2.50-5.48), 3.71, 4.81 (2.57-8.99) | LD50's determined at ages 36 hr, 7 d, 30 d, and 6 mos, respectively (95% CI in parenth.) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
ARSENATE, SODIUM | no effect | hematocrit and hemoglobin | Both Male and Female | Juvenile | 30 birds/group | 0, 30, 100, 300 ppm | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 10 wks | diet | Toxicity Factor Datasets |
ARSENATE, SODIUM | increased @ 100 ppm ( 0.4 ppm, dry wt), 300 ppm (0.8 ppm, dry wt) | accumulation of arsenic in brain tissue (geometric means in parentheses) | Both Male and Female | Juvenile | 30 birds/group | 0, 30, 100, 300 ppm | TOX-EXP IND - accumulation | 10 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
EPN | decreased @ 12, 36 ug/g | brain weight, protein content, acetylcholinesterase and neurotoxic esterase versus controls | Not Reported | Hatchling | 12/group | 0,12,36,108 ug/g egg | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | application to egg surface | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | ppm wet wt: 1.40 (0.7), blood; 6.40 (4.92), liver; 38.64 (19.18), femur @ 2 #four shot | mean (2SE) lead concentrations in liver, femur and blood | Male | Adult | Sacramento National Wildlife Refuge | 31 birds | 931,000 shot/acre (field exposure) | TOX-EXP IND - accumulation | 80 d | ingestion | Toxicity Factor Datasets |
LEAD (elemental) | ppm wet wt: 1.21 (0.78), blood; 2.32 (1.10), liver; 131.13 (90.94), femur @ 2 #four shot | mean (2SE) lead concentrations in liver, femur and blood | Female | Adult | Sacramento National Wildlife Refuge | 24 birds | 931,000 shot/acre (field exposure) | TOX-EXP IND - accumulation | 80 d | ingestion | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | ppm, wet wt: 0.79-0.86 (egg); 0.89-1.62 (liver); 1.52-1.82 (kidney); 9.03-11.17 (primary feathers); 0.67-0.83 (breast muscle); 0.44-0.59 (brain); 0.51-0.65 (ovary) | mean concentration of Hg in tissues (ranges are for 3 generations) | Female | Adult | 3-14 birds/tissue x generation group | 0.5 ppm Hg in diet | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
METHYLMERCURY DICYANDIAMIDE | no effect | body weight versus controls | Both Male and Female | Adult | 14 pairs/group | 0, 0.5 ppm Hg in diet | TOX-Non-Repro-Sublethal - whole animal | NR | diet | Toxicity Factor Datasets |
METHYLMERCURY DICYANDIAMIDE | increased in 2nd generation | food consumption versus controls | Both Male and Female | Adult | 14 pairs/group | 0, 0.5 ppm Hg in diet | TOX-Non-Repro-Sublethal - behavioral effects | NR | diet | Toxicity Factor Datasets |
METHYLMERCURY DICYANDIAMIDE | decreased in 3rd generation | eggshell thickness versus controls | Female | Adult | 14 pairs/group | 0, 0.5 ppm Hg in diet | TOX-REPRO - physiology | NR | diet | Toxicity Factor Datasets |
METHYLMERCURY DICYANDIAMIDE | increased in 2nd generation | proportion of eggs laid outside nestbox | Female | Adult | 14 pairs/group | 0, 0.5 ppm Hg in diet | TOX-REPRO - behavior | NR | diet | Toxicity Factor Datasets |
METHYLMERCURY DICYANDIAMIDE | no effect | hatchability and duckling survival versus controls | Not Reported | Juvenile | 14 pairs/group | 0, 0.5 ppm Hg in diet | TOX-REPRO - reproductive success | NR | diet | Toxicity Factor Datasets |
METHYLMERCURY DICYANDIAMIDE | decreased in 3rd generation | proportion of ducklings responding to approach and avoidance stimuli | Not Reported | Juvenile | 14 pairs/group | 0, 0.5 ppm Hg in diet | TOX-REPRO - development | NR | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | no effect | body weight compared to controls | Both Male and Female | Adult | 20 females, 10 males/group | 0, 1, 2 lead shot (206 mg avg wt) | TOX-Non-Repro-Sublethal - whole animal | Single dose (one shot); repeated dose (two shot) | Gavage | Toxicity Factor Datasets |
LEAD (elemental) | no effect | egg production versus controls | Female | Adult | 20 females/group | 0, 1, 2 lead shot (206 mg avg wt) | TOX-REPRO - reproductive success | Single dose (one shot); repeated dose (two shot) | Gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM, SELENOMETHIONINE | no effect | tarsus length, 10th primary length, heart weight versus controls | Not Reported | Juvenile | 40 birds/group | 0, 10 ppm Se as selenomethionine or sodium selenite | TOX-Non-Repro-Sublethal - whole animal | 6 weeks | Diet | Toxicity Factor Datasets |
SELENITE, SODIUM | 18(4.8) ppm, wet wt @ 40 ppm; 6.9(2.07) ppm, wet wt @ 80 ppm | mean liver concentrations (SE) in ducklings fed selenite that died | Not Reported | Juvenile | 40 birds/group | 0, 10, 20, 40, or 80 ppm Se as sodium selenite | TOX-EXP IND - accumulation | 6 weeks | Diet | Toxicity Factor Datasets |
SELENOMETHIONINE | 60(14.2) ppm, wet wt @ 40 ppm; 51(5.2) ppm, wet wt @ 80 ppm | mean liver concentrations (SE) in ducklings fed selenomethionine that died | Not Reported | Juvenile | 40 birds/group | 0, 10, 20, 40, or 80 ppm Se as selenomethionine | TOX-EXP IND - accumulation | 6 weeks | Diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decreased @ 1, 5 uL/egg | bill length of both sexes | Both Male and Female | Hatchling | 65 eggs/group | 0, 1, or 5 uL | TOX-REPRO - development | Single exposure | Topical on eggshell | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | no effect | % survival versus controls | Not Reported | Juvenile | 15/group | 0, 15, or 60 ppm Se; with and without added methionine, and varying protein levels | TOX-MORT - dose-response data | 4 weeks | Dietary | Toxicity Factor Datasets |
SELENOMETHIONINE | 11.6 (@15 ppm diet), 48.6 (@ 60 ppm diet) ppm, wet wt | geometric mean Se concentration in liver (adequate protein in diet) | Not Reported | Juvenile | 15/group | 0, 15, or 60 ppm Se; with and without added methionine, and varying protein levels | TOX-EXP IND - accumulation | 4 weeks | Dietary | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease @ 5, 15 ul/egg | red blood cell and liver ALAD activity, hemoglobin concentration, plasma uric acid, and plasma ALT and AST activities compared to controls | Both Male and Female | Hatchling | 100 eggs/dose | 0, 2, 5, 15 ul waste crankcase oil/egg | TOX-REPRO - physiology | single | application to egg surface | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increased with light, moderate and heavy oiling | thermal conductance of feathers and body heat loss versus controls | Both Male and Female | Adult | 3 birds/treatment | 0, light, moderate, and heavy exposure | TOX-Non-Repro-Sublethal - whole animal | single exposure, 1-4 hrs | in bathing water | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
PENTACHLOROPHENOL | decrease @ 961 ug/g | total body weight, compared to control; reported as the LOAEL for the study | Not Reported | Juvenile | 6/dose | 25.0, 54.2, 105.0, 233.2, 423.2, 961.0 ug/g diet | TOX-REPRO - development | 11 d | diet | Toxicity Factor Datasets |
PENTACHLOROPHENOL | no effect @ 423.2 ug/g | total body weight, compared to control; reported as the NOAEL for the study | Not Reported | Juvenile | 6/dose | 25.0, 54.2, 105.0, 233.2, 423.2, 961.0 ug/g diet | TOX-REPRO - development | 11 d | diet | Toxicity Factor Datasets |
PENTACHLOROPHENOL | 22.2 +/- 5.5 ug/g lipid, 30.7 +/- 10.3 ug/g liver, 11.0 +/- 0 ug/g muscle, 4.0 +/- 1.4 ug/g brain at 961 ug/g diet | mean +/- SD tissue concentrations at the reported LOAEL (development) | Not Reported | Juvenile | 4-6 | 25.0, 54.2, 105.0, 233.2, 423.2, 961.0 ug/g diet | TOX-EXP IND - accumulation | 11 d | diet | Toxicity Factor Datasets |