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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-), POLYCHLORINATED BIPHENYLS | 7% decrease | eggshell thickness compared with pre-1947 reference eggs | Female | Adult | Cape Romain National Wildlife Refuge | 20 eggs | 0.48 ug/g, wet wt, DDE; 1.08 ug/g, wet wt, PCBs in eggs | TOX-REPRO - physiology | NR | site contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LINDANE | 18-21% decrease @ 20 mg/kg 7x or 3x/wk | eggshell thickness, compared to control | Female | Adult | 5/dose | control, 20 mg/kg given 7x, 3x or 2x/wk | TOX-REPRO - physiology | 8 wks | gavage | Toxicity Factor Datasets |
LINDANE | decrease @ 20 mg/kg 7x or 3x/wk | calcium concentration in plasma and shell gland mucosa and density and size of eggshell pores | Female | Adult | 5/dose | control, 20 mg/kg given 7x, 3x or 2x/wk | TOX-REPRO - physiology | 8 wks | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|
DDT (Technical Grade Mixture) | increase @ 0.05 - 0.4% in diet | Not Reported | Not Reported | 4/dose | 0, 0.025, 0.05, 0.1, 0.2, 0.4% | TOX-MORT - dose-response data | 30 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDT (Technical Grade Mixture) | no effect | fertility, hatchability and duckling weight | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-REPRO - reproductive success | 343 d | diet | Toxicity Factor Datasets |
DDT (4,4'-) | no effect | fertility, hatchability and duckling weight | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-REPRO - reproductive success | 343 d | diet | Toxicity Factor Datasets |
DIELDRIN | no effect | fertility, hatchability and duckling weight | Female | Adult | 18/dose | 0, 1, 5, 10 mg/kg diet | TOX-REPRO - reproductive success | 343 d | diet | Toxicity Factor Datasets |
DDT (Technical Grade Mixture) | no effect | hepatic microsomal enzyme activity (aniline hydroxylase and aminopyrine N-demethylase) | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 343 d | diet | Toxicity Factor Datasets |
DDT (4,4'-) | no effect | hepatic microsomal enzyme activity (aniline hydroxylase and aminopyrine N-demethylase) | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 343 d | diet | Toxicity Factor Datasets |
DIELDRIN | no effect | hepatic microsomal enzyme activity (aniline hydroxylase and aminopyrine N-demethylase) | Female | Adult | 18/dose | 0, 1, 5, 10 mg/kg diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 343 d | diet | Toxicity Factor Datasets |
DDT (Technical Grade Mixture) | DDT <0.1, DDE 0.2 - 1.2 ug/g dry wt @ 0 ppm; DDT 0.3 - 4.2, DDE 1.0 - 12.7 @ 2 ppm; DDT 1.3 - 25.0, DDE 5.0 - 110.1 @ 20 ppm; DDT 25.5 - 254, DDE 58.0 - 1234 @ 200 ppm | DDT and DDE concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-EXP IND - accumulation | 343 d | diet | Toxicity Factor Datasets |
DDT (4,4'-) | DDT <0.1, DDE 0.2 - 1.2 ug/g dry wt @ 0 ppm; DDT 0.6 - 2.4, DDE 1.2 - 10.1 @ 2 ppm; DDT 2.2 - 29.2, DDE 15.7 - 153.5 @ 20 ppm; DDT 14.9 - 102.0, DDE 45.0 - 187.0 @ 200 ppm | DDT and DDE concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-EXP IND - accumulation | 343 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
TRIETHYLTIN CHLORIDE | decrease @ 50 ppm | body weight, compared to control | Not Reported | Juvenile | 5/dose | control, 0.5, 5.0, 50 ppm (Sn) as triethyltin chloride | TOX-Non-Repro-Sublethal - whole animal | 73 - 75 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | egg production, eggshell thickness and fertility, compared to control | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 4 ppm | TOX-REPRO - physiology | 90 d | diet | Toxicity Factor Datasets |
DIELDRIN | decrease | average % hatchability, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 4 ppm | TOX-REPRO - reproductive success | 90 d | diet | Toxicity Factor Datasets |
DIELDRIN | no effect | progeny growth (average body weights) at hatch to 6 wks of age | Both Male and Female | Juvenile | 5 trios (2F, 1M adults)/dose | control, 4 ppm | TOX-REPRO - development | 90 d | diet | Toxicity Factor Datasets |
PARATHION | no effect | egg production and fertility, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 10 ppm | TOX-REPRO - physiology | 90 d | diet | Toxicity Factor Datasets |
PARATHION | no effect | % hatchability, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 10 ppm | TOX-REPRO - reproductive success | 90 d | diet | Toxicity Factor Datasets |
PARATHION | decrease | eggshell thickness, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 10 ppm | TOX-REPRO - physiology | 90 d | diet | Toxicity Factor Datasets |
PARATHION | no effect | progeny growth (average body weights) at hatch to 6 wks of age | Both Male and Female | Juvenile | 5 trios (2F, 1M adults)/dose | control, 10 ppm | TOX-REPRO - development | 90 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
RADIONUCLIDES | see citation | table of mean concentrations of 6 radionuclides (238Pu, 239Pu, 241Am, 242Cm, 244Cm, 90Sr) in 6 mallard tissue types | Not Reported | Adult | leaching ponds, Test Reactor Area, Idaho National Engineering Laboratory | 7-15 | see citation for table radionuclide concentrations in water, plankton, periphyton, sediment | TOX-EXP IND - accumulation | 43-145 d | site contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 5.7 ppm (whole blood); 6.2 ppm (liver); 2.4 ppm (spleen) @ 300 mg/kg body weight | lead concentrations in tissues, 96 hr after exposure to lead in ducklings receiving vitamin E | Not Reported | Juvenile | 5/dose | control, 300 mg/kg body weight; elemental lead packaged in gelatin capsules | TOX-EXP IND - accumulation | single | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | increase @ 15, 30 ppm | plasma and liver GSH-peroxidase activity (for all Se forms), compared to controls | Not Reported | Juvenile | 10/dose | control, 15, 30 ppm Se as seleno-D,L-methionine, seleno-L-methionine or selenized yeast | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 2 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 10.3(0.7) ppm in femur, 14.1(0.6) ppm in liver, 6.8(0.2) in kidneys | mean(SE) dry wt tungsten concentrations in tissues of tungsten-iron-dosed birds | Both Male and Female | Adult | 16/treatment | control, steel (eight #4 pellets), lead (eight #4 pellets), tungsten-iron (eight BB size pellets), tungsten-polymer (eight BB size pellets); See paper for data on shot recovery and erosion in dosed ducks. | TOX-EXP IND - accumulation | single exposure; 30 d observation | oral | Toxicity Factor Datasets |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 4.3(0.7) ppm in femur, non-detect. in liver, 2.4(0.2) in kidneys | mean(SE) dry wt tungsten concentrations in tissues of tungsten-polymer-dosed birds | Both Male and Female | Adult | 16/treatment | control, steel (eight #4 pellets), lead (eight #4 pellets), tungsten-iron (eight BB size pellets), tungsten-polymer (eight BB size pellets); See paper for data on shot recovery and erosion in dosed ducks. | TOX-EXP IND - accumulation | single exposure; 30 d observation | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean survival times compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | five #4 pellets of lead, iron, or bismuth/tin embedded in breast muscle | TOX-MORT - dose-response data | 185 and 365 d | embedded in muscle | Toxicity Factor Datasets |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean body weight and organ weights compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | five #4 pellets of lead, iron, or bismuth/tin embedded in breast muscle | TOX-Non-Repro-Sublethal - whole animal | 185 and 365 d | embedded in muscle | Toxicity Factor Datasets |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean hematocrit values compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | five #4 pellets of lead, iron, or bismuth/tin embedded in breast muscle | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 185 and 365 d | embedded in muscle | Toxicity Factor Datasets |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | 130(10.1) ppm in kidneys, 0.19(0.06) ppm in liver | mean(SE) wet wt concentration of bismuth in organs | Both Male and Female | Adult | 5 males, 5 females per group | five #4 pellets of lead, iron, or bismuth/tin embedded in breast muscle | TOX-EXP IND - accumulation | 185 and 365 d | embedded in muscle | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | no effect | incidence of illness versus controls | Both Male and Female | Adult | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-Non-Repro-Sublethal - whole animal | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS, SELENOMETHIONINE | no effect | egg fertility, egg weight, eggshell thickness, and mean interval between laying of eggs versus controls | Both Male and Female | Adult | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-REPRO - physiology | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-L-methionine or seleno-D,L-methionine | hatchability versus controls | Both Male and Female | Both Adults and Juveniles | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-REPRO - reproductive success | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-L-methionine | duckling survival compared to controls | Both Male and Female | Adult | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-REPRO - reproductive success | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-D,L-methionine, seleno-L-methionine, or selenized yeast | number of 6-day-old ducklings produced per female versus controls | Both Male and Female | Both Adults and Juveniles | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-REPRO - reproductive success | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | significant effect | PCB treatment altered the shape of the body weight growth curve but not the asymptotic weight | Both Male and Female | Juvenile | 15/dose | 0, 0.5, 5.0, 50 mg/kg diet | TOX-Non-Repro-Sublethal - whole animal | 12 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1242 | no effect @ 150 ppm | mortality during experiment | Both Male and Female | Adult | 12 pairs/dose | 0, 150 mg/kg diet | TOX-MORT - dose-response data | 12 wks | diet | Toxicity Factor Datasets |
AROCLOR 1242 | decrease @ 150 ppm | body weight at 6, 8 and 12 wks of treatment | Female | Adult | 12 pairs/dose | 0, 150 mg/kg diet | TOX-Non-Repro-Sublethal - whole animal | 12 wks | diet | Toxicity Factor Datasets |
AROCLOR 1242 | no effect @ 150 ppm | embryo mortality, # infertile eggs/clutch or # eggs hatched/clutch | Female | Adult | 12 pairs/dose | 0, 150 mg/kg diet | TOX-REPRO - reproductive success | 12 wks | diet | Toxicity Factor Datasets |
AROCLOR 1242 | 8.9% decrease @ 150 ppm | eggshell thickness, compared to control | Female | Adult | 12 pairs/dose | 0, 150 mg/kg diet | TOX-REPRO - physiology | 12 wks | diet | Toxicity Factor Datasets |
AROCLOR 1242 | 105.0 (7.7 SE) mg Aroclor 1260/kg egg @ 150 ppm | PCB concentration in eggs (PCB resembled Aroclor 1260 profile most closely) | Female | Adult | 12 pairs/dose | 0, 150 mg/kg diet | TOX-EXP IND - accumulation | 12 wks | diet | Toxicity Factor Datasets |