LEAD (elemental)
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased @ 7, 14, 21 d post-dose | concentration of lead in blood versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | no effect | body weight versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increased @ 1 #four shot | mortality rate by 15 d post-dose versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | decreased @ 1 #four shot, 7, 14, 21 d. post-dose | agglutination titers to sheep red blood cells versus controls | Male | Adult | 4/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased in all groups dosed with lead shot | incidence of clinical signs, weight loss, breast muscle atrophy | Both Male and Female | Adult | treatment = 10/group control = 5 |
Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increased with Pb/corn+Ca (50%), and Pb/corn only (100%) | % mortality versus controls | Both Male and Female | Adult | treatment = 10/group control = 5 |
Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | decreased in Pb/commerical (hemoglobin only), Pb/corn+Ca, and Pb/corn only | red blood cell counts, packed cell volume, hemoglobin concentration versus controls | Both Male and Female | Adult | treatment = 10/group control = 5 |
Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increased with Pb/corn + Ca, Pb/corn only | blood protoporphyrin concentrations versus controls | Both Male and Female | Adult | treatment = 10/group control = 5 |
Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | increased for lead shot, steel and tungsten-iron groups | iron concentrations in femur and liver versus controls | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory | |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | increased for lead, steel shot | renal concentrations of iron versus controls | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory | |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 250.6(39.0) ppm in femur, 78.3(9.7) ppm in liver, 256.3(22.2) in kidneys | mean(SE) dry wt lead concentrations in tissues of lead-dosed birds | Both Male and Female | Adult | 16/treatment | Toxicity Factor Datasets | 6 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | 1.54(0.280) ppm, kidney; 0.637(0.134) ppm, liver; 0.042(0.007) ppm, ovary; 0.098(0.042) ppm, testis | mean(SE) wet wt concentrations of Bi in Bi-dosed birds | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | increased with Pb, no effect with Fe or Bi | mortality versus controls | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | decreased with Pb; no effect with Fe or Bi | body weight, gonad weight, hematocrit versus controls | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | increased with Pb; no effect with Fe or Bi | gizzard and kidney weight versus controls | Both Male and Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | decreased with Pb | liver weight versus controls (females only) | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no effect with Fe or Bi | onset of lay and time to lay 21 eggs versus controls | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | increased with Fe | weight of eggs that hatched versus controls | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory | |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | increased with Bi | weight of eggs that did not hatch versus controls | Female | Adult | 18 pairs/group (control, Fe, Bi); 6 pairs/Pb group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | one shot: 180.4 (18.1), female; 5.0 (0.6), male two shot: 183.4 (21.2), female; 15.9 (4.1), male |
mean (SE) lead residues in femur | Both Male and Female | Adult | 20 females, 10 males/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | no effect | body weight compared to controls | Both Male and Female | Adult | 20 females, 10 males/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | no effect | egg production versus controls | Female | Adult | 20 females/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | 130(10.1) ppm in kidneys, 0.19(0.06) ppm in liver | mean(SE) wet wt concentration of bismuth in organs | Both Male and Female | Adult | 5 males, 5 females per group | Toxicity Factor Datasets | 6-8 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased | blood ALAD enzyme activity after 1,2, or 3 months versus pre-dose controls | Both Male and Female | Adult | 20 per sex | laboratory | Toxicity Factor Datasets | 8 months | Laboratory |
LEAD (elemental) | increased | blood Pb concentrations versus pre-dose controls | Both Male and Female | Adult | 20 per sex | laboratory | Toxicity Factor Datasets | 8 months | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased | body weight and delta-aminolevulinic acid dehydratase activity versus controls | Male | Adult | 20/treatment group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increased | erythrocyte protoporphyrin concentrations versus controls | Male | Adult | 20/treatment group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | no effect | body weight and hematocrit versus controls | Male | Juvenile | 20/treatment group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | 60% @ 2 shot, 30% @ 4 shot | cumulative mortality | Male | Adult | 10/treatment group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decreased | hemoglobin and hematocrit versus controls | Male | Juvenile | 8 | Laboratory | Toxicity Factor Datasets | 6 months | Laboratory |
LEAD (elemental) | decreased (60%) | blood ALAD activity versus controls | Male | Juvenile | 8 | Laboratory | Toxicity Factor Datasets | 6 months | Laboratory |
LEAD (elemental) | increased | blood protoporphyrin levels versus controls | Male | Juvenile | 8 | Laboratory | Toxicity Factor Datasets | 6 months | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | no effect | body weight and food consumption versus controls | Both Male and Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
LEAD (elemental) | no effect | incidence of lead poisoning tissue lesions versus controls | Both Male and Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
LEAD (elemental) | lead only: 112.27 (+/- 44.27); lead-iron: 32.65 (+/- 16.58) ppm, wet wt | lead concentration in bone (mean +/- SE) | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
LEAD (elemental) | lead only: 10.22 (+/- 1.46); lead-iron: 3.38 (+/- 0.56) ppm, wet wt | lead concentration in bone (mean +/- SE) | Male | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
LEAD (elemental) | lead only: 0.71 (+/- 0.25); lead-iron: 0.31 (+/- 0.06) ppm, wet wt | lead concentration in blood (mean +/- SE) | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory | |
LEAD (elemental) | lead only: 0.49 (+/-0.10); lead-iron: 0.23 (+/- 0.04) ppm, wet wt | lead concentration in blood (mean +/- SE) | Male | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | Toxicity Factor Datasets | 6 mos | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | California Counties | Lab |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | ppm wet wt: 1.40 (0.7), blood; 6.40 (4.92), liver; 38.64 (19.18), femur @ 2 #four shot | mean (2SE) lead concentrations in liver, femur and blood | Male | Adult | 31 birds | Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | |
LEAD (elemental) | ppm wet wt: 1.21 (0.78), blood; 2.32 (1.10), liver; 131.13 (90.94), femur @ 2 #four shot | mean (2SE) lead concentrations in liver, femur and blood | Female | Adult | 24 birds | Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | |
LEAD (elemental) | increased @ 2 #four shot | mortality versus controls | Both Male and Female | Adult | 12 (control); 16 (lab); 63 (field) | Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | Laboratory |
LEAD (elemental) | decreased @ 931,000 shot/acre or 2 #four pellets | spleen weight and total white blood cell counts versus controls | Both Male and Female | Adult | 12 (control); 16 (lab); 63 (field) | Sacramento National Wildlife Refuge | Toxicity Factor Datasets | 1 yr | Sacramento | Laboratory |
LEAD (elemental) | ppm wet wt: 3.47 (1.38), blood; 32.16 (11.60), liver; 114.78 (28.96), femur @ 2 #four shot | mean (2SE) lead concentration in liver, femur and blood | Male | Adult | 11 birds | Toxicity Factor Datasets | 1 yr | Laboratory | ||
LEAD (elemental) | ppm wet wt: 4.15 (3.56), blood; 13.85 (7.96), liver; 577.07 (156.4), femur@ 2 #four shot | mean (2SE) lead concentrations in liver, femur and blood | Female | Adult | 5 birds | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased @ 5 shot (33%) and repeated 5 shot (40%) | percent mortality versus controls | Both Male and Female | Not Reported | 5-6/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | decreased | bw versus controls | Both Male and Female | Not Reported | 5-6/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increased @ all doses | Pb concentrations in wing bone and liver | Both Male and Female | Not Reported | 5-6/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | California Counties |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | higher in P8 than in T19 and TF, and in T19 than in TF | maximum likelihood estimate of 2-week Pb exposure rate | Both Male and Female | Both Adults and Juveniles | 50 birds/treatment | Sacramento National Wildlife Refuge; Willows, CA (39deg29'N, 122deg20'W) | Toxicity Factor Datasets | Sacramento |
LEAD (elemental) | higher in P8 than in T19 and TF, and in T19 than in TF | mortality rate (over 4 years) | Both Male and Female | Both Adults and Juveniles | 50 birds/treatment | Sacramento National Wildlife Refuge; Willows, CA (39deg29'N, 122deg20'W) | Toxicity Factor Datasets | Sacramento |
American Kestrel (Falco sparverius)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decrease at 125, 625 mg/kg bw (71-79%) | kidney delta aminolevulinic acid dehydratase activity | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | decrease at 125, 625 mg/kg bw (20-25%) | liver delta aminolevulinic acid dehydratase activity | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 40% at 625 mg/kg bw | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory | ||
LEAD (elemental) | decrease at 125, 625 mg/kg bw | body weight at end of dosing relative to control | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | decrease at 125, 625 mg/kg bw | growth rate relative to control | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increase at all doses 1.4, 3.5, 5.5 ppm at 25, 125, 625 mg/kg bw, respectively |
liver lead concentration | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increase at 125, 625 mg/kg bw 7.2, 15.5 ppm at 125, 625 mg/kg bw, respectively |
kidney lead concentrations | Both Male and Female | Nestling | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | decrease at 10, 50 ppm | mean blood delta aminolevulinic acid dehydratase | Both Male and Female | Adult | 16 pairs/dose | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | no effect | mean packed cell volume and red blood cell hemoglobin | Both Male and Female | Adult | 16 pairs/dose | Toxicity Factor Datasets | Laboratory |
Mourning Dove (Zenaida macroura)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 639.43 and 345.95 ug/g, dry wt | lead concentration in kidneys of treated birds | Not Reported | Not Reported | 2 | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | 58.35 and 214.71 ug/g, dry wt | lead concentrations in livers of dosed birds | Not Reported | Not Reported | 2 | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | light to moderate lesions | histological exam for hemosiderin loading in liver | Not Reported | Not Reported | 2 | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | high degree of lesions present | histological exam of acid-fast intranuclear inclusions of cells of kidney proximal convoluted tubules | Not Reported | Not Reported | 1 | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | high degree of lesions present | histological exam for hemosiderin loading in liver | Not Reported | Not Reported | 1 | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | 1,297.57 ug/g, dry wt | lead concentration in kidneys | Not Reported | Not Reported | 1 | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | 178.81 ug/g, dry wt | lead concentration in liver | Not Reported | Not Reported | 1 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | no effect | mortality in dosed birds | Female | Adult | 12/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | no effect | body weight | Female | Adult | 12/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | 65.4-123.2 ug/g, dry wt | mean lead concentrations in femur (greater accumulation with mixed seed vs. pelleted diet) | Female | Adult | 12/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | 2.80-4.98 ug/g, dry wt | mean lead concentrations in liver (greater accumulation with mixed seed vs. pelleted diet) | Female | Adult | 12/group | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | 47.2-190.7 ug/g, dry wt | mean lead concentrations in kidney (greater accumulation with mixed seed vs. pelleted diet) | Female | Adult | 12/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased at all doses | mortality | Not Reported | Adult | 25 birds/dose | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | no effect | female fertility or productivity, egg weight and size | Female | Adult | 25 birds/dose | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | decreased | hatchability | Not Reported | Hatchling | 25 birds/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased at 1, 4 shots | mortality | Both Male and Female | Adult | 10 birds/dose | Toxicity Factor Datasets | Laboratory | |
LEAD (elemental) | increased at all doses | lead concentrations in blood | Both Male and Female | Adult | 10 birds/dose | Toxicity Factor Datasets | Laboratory |