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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | hepatic microsomal enzyme activity (aniline hydroxylase and aminopyrine N-demethylase) | Female | Adult | 18/dose | 0, 1, 5, 10 mg/kg diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 343 d | diet | Toxicity Factor Datasets |
DDT (Technical Grade Mixture) | DDT <0.1, DDE 0.2 - 1.2 ug/g dry wt @ 0 ppm; DDT 0.3 - 4.2, DDE 1.0 - 12.7 @ 2 ppm; DDT 1.3 - 25.0, DDE 5.0 - 110.1 @ 20 ppm; DDT 25.5 - 254, DDE 58.0 - 1234 @ 200 ppm | DDT and DDE concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-EXP IND - accumulation | 343 d | diet | Toxicity Factor Datasets |
DDT (4,4'-) | DDT <0.1, DDE 0.2 - 1.2 ug/g dry wt @ 0 ppm; DDT 0.6 - 2.4, DDE 1.2 - 10.1 @ 2 ppm; DDT 2.2 - 29.2, DDE 15.7 - 153.5 @ 20 ppm; DDT 14.9 - 102.0, DDE 45.0 - 187.0 @ 200 ppm | DDT and DDE concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-EXP IND - accumulation | 343 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
TRIETHYLTIN CHLORIDE | decrease @ 50 ppm | body weight, compared to control | Not Reported | Juvenile | 5/dose | control, 0.5, 5.0, 50 ppm (Sn) as triethyltin chloride | TOX-Non-Repro-Sublethal - whole animal | 73 - 75 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | egg production, eggshell thickness and fertility, compared to control | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 4 ppm | TOX-REPRO - physiology | 90 d | diet | Toxicity Factor Datasets |
DIELDRIN | decrease | average % hatchability, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 4 ppm | TOX-REPRO - reproductive success | 90 d | diet | Toxicity Factor Datasets |
DIELDRIN | no effect | progeny growth (average body weights) at hatch to 6 wks of age | Both Male and Female | Juvenile | 5 trios (2F, 1M adults)/dose | control, 4 ppm | TOX-REPRO - development | 90 d | diet | Toxicity Factor Datasets |
PARATHION | no effect | egg production and fertility, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 10 ppm | TOX-REPRO - physiology | 90 d | diet | Toxicity Factor Datasets |
PARATHION | no effect | % hatchability, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 10 ppm | TOX-REPRO - reproductive success | 90 d | diet | Toxicity Factor Datasets |
PARATHION | decrease | eggshell thickness, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 10 ppm | TOX-REPRO - physiology | 90 d | diet | Toxicity Factor Datasets |
PARATHION | no effect | progeny growth (average body weights) at hatch to 6 wks of age | Both Male and Female | Juvenile | 5 trios (2F, 1M adults)/dose | control, 10 ppm | TOX-REPRO - development | 90 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
RADIONUCLIDES | see citation | table of mean concentrations of 6 radionuclides (238Pu, 239Pu, 241Am, 242Cm, 244Cm, 90Sr) in 6 mallard tissue types | Not Reported | Adult | leaching ponds, Test Reactor Area, Idaho National Engineering Laboratory | 7-15 | see citation for table radionuclide concentrations in water, plankton, periphyton, sediment | TOX-EXP IND - accumulation | 43-145 d | site contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 5.7 ppm (whole blood); 6.2 ppm (liver); 2.4 ppm (spleen) @ 300 mg/kg body weight | lead concentrations in tissues, 96 hr after exposure to lead in ducklings receiving vitamin E | Not Reported | Juvenile | 5/dose | control, 300 mg/kg body weight; elemental lead packaged in gelatin capsules | TOX-EXP IND - accumulation | single | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | increase @ 15, 30 ppm | plasma and liver GSH-peroxidase activity (for all Se forms), compared to controls | Not Reported | Juvenile | 10/dose | control, 15, 30 ppm Se as seleno-D,L-methionine, seleno-L-methionine or selenized yeast | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 2 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 10.3(0.7) ppm in femur, 14.1(0.6) ppm in liver, 6.8(0.2) in kidneys | mean(SE) dry wt tungsten concentrations in tissues of tungsten-iron-dosed birds | Both Male and Female | Adult | 16/treatment | control, steel (eight #4 pellets), lead (eight #4 pellets), tungsten-iron (eight BB size pellets), tungsten-polymer (eight BB size pellets); See paper for data on shot recovery and erosion in dosed ducks. | TOX-EXP IND - accumulation | single exposure; 30 d observation | oral | Toxicity Factor Datasets |
LEAD (elemental), STEEL COMPOUNDS, TUNGSTEN COMPOUNDS | 4.3(0.7) ppm in femur, non-detect. in liver, 2.4(0.2) in kidneys | mean(SE) dry wt tungsten concentrations in tissues of tungsten-polymer-dosed birds | Both Male and Female | Adult | 16/treatment | control, steel (eight #4 pellets), lead (eight #4 pellets), tungsten-iron (eight BB size pellets), tungsten-polymer (eight BB size pellets); See paper for data on shot recovery and erosion in dosed ducks. | TOX-EXP IND - accumulation | single exposure; 30 d observation | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean survival times compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | five #4 pellets of lead, iron, or bismuth/tin embedded in breast muscle | TOX-MORT - dose-response data | 185 and 365 d | embedded in muscle | Toxicity Factor Datasets |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean body weight and organ weights compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | five #4 pellets of lead, iron, or bismuth/tin embedded in breast muscle | TOX-Non-Repro-Sublethal - whole animal | 185 and 365 d | embedded in muscle | Toxicity Factor Datasets |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | no differences | mean hematocrit values compared among lead, iron and bismuth dosed birds | Both Male and Female | Adult | 5 males, 5 females per group | five #4 pellets of lead, iron, or bismuth/tin embedded in breast muscle | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 185 and 365 d | embedded in muscle | Toxicity Factor Datasets |
BISMUTH COMPOUNDS, IRON COMPOUNDS, LEAD (elemental) | 130(10.1) ppm in kidneys, 0.19(0.06) ppm in liver | mean(SE) wet wt concentration of bismuth in organs | Both Male and Female | Adult | 5 males, 5 females per group | five #4 pellets of lead, iron, or bismuth/tin embedded in breast muscle | TOX-EXP IND - accumulation | 185 and 365 d | embedded in muscle | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | no effect | incidence of illness versus controls | Both Male and Female | Adult | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-Non-Repro-Sublethal - whole animal | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS, SELENOMETHIONINE | no effect | egg fertility, egg weight, eggshell thickness, and mean interval between laying of eggs versus controls | Both Male and Female | Adult | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-REPRO - physiology | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-L-methionine or seleno-D,L-methionine | hatchability versus controls | Both Male and Female | Both Adults and Juveniles | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-REPRO - reproductive success | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-L-methionine | duckling survival compared to controls | Both Male and Female | Adult | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-REPRO - reproductive success | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS, SELENOMETHIONINE | reduced with seleno-D,L-methionine, seleno-L-methionine, or selenized yeast | number of 6-day-old ducklings produced per female versus controls | Both Male and Female | Both Adults and Juveniles | 15 pairs/treatment group, 10 pairs/control group | 0, 10.3 ppm Se as seleno-L-methionine, 9.3 ppm Se as seleno-D,L-methionine, and 10.9 ppm Se as selenized yeast | TOX-REPRO - reproductive success | through reproduction until 6 days of age in ducklings | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254 | significant effect | PCB treatment altered the shape of the body weight growth curve but not the asymptotic weight | Both Male and Female | Juvenile | 15/dose | 0, 0.5, 5.0, 50 mg/kg diet | TOX-Non-Repro-Sublethal - whole animal | 12 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1242 | no effect @ 150 ppm | mortality during experiment | Both Male and Female | Adult | 12 pairs/dose | 0, 150 mg/kg diet | TOX-MORT - dose-response data | 12 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
AMMONIUM NITRATE | significantly increased (138.5% +/- 86.1 SD) | percent increase in breeding territory size post-spray vs. unsprayed controls | Both Male and Female | Both Adults and Juveniles | MacArthur Agroecology Research Center, Archbold Biological Station | 4 control, 8 treatment territories | 54 kg/ha application rate | TOX-Non-Repro-Sublethal - indirect effects | approx. 1 month | application to habitat | Toxicity Factor Datasets |
AMMONIUM NITRATE | significantly earlier | timing of nesting season termination in pairs post-spray vs. unsprayed controls | Both Male and Female | Both Adults and Juveniles | MacArthur Agroecology Research Center, Archbold Biological Station | 4 control, 8 treatment territories | 54 kg/ha application rate | TOX-Non-Repro-Sublethal - indirect effects | approx. 1 month | application to habitat | Toxicity Factor Datasets |
AMMONIUM NITRATE | increased | loss of eggs, nestlings, fledglings and adults post-spray vs. unsprayed controls | Both Male and Female | Both Adults and Juveniles | MacArthur Agroecology Research Center, Archbold Biological Station | 4 control, 8 treatment territories | 54 kg/ha application rate | TOX-Non-Repro-Sublethal - indirect effects | approx. 1 month | application to habitat | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
PARA-AMINOPROPIOPHENONE | 5.6 [3.0-10.4 (95% CI)] mg/kg | LD50 | Not Reported | Not Reported | 4/dose | 3 doses | TOX-MORT - toxicity benchmarks | single | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIPHACINONE | 0.6 [0.3 - 1.2 (95% CL)] mg/kg | LD50 | Both Male and Female | Adult | 2/dose | 0, 0.16, 0.31, 0.63, 1.25, 2.5, 5.0 and 10.0 mg/kg | TOX-MORT - toxicity benchmarks | single | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LITHIUM CHLORIDE | decrease @ 18g/1500 g/d | body weight gain in nursing pups of mothers fed LiCl contaminated diet | Both Male and Female | Both Adults and Juveniles | 4 pups/2 adults | 3 or 18 g LiCl/1500 g jackrabbit/d | TOX-Non-Repro-Sublethal - whole animal | 3 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SODIUM MONOFLUOROACETATE | increase @ 535-9754 ppb | all coyotes died after ingesting 1-2 ground squirrels poisoned with sodium monofluoroacetate | Not Reported | Pup | 2 | 535-9754 ppb wet wt. fluoroacetate in tissues of poisoned squirrels | TOX-MORT - dose-response data | 12 hr | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SODIUM MONOFLUOROACETATE | increase @ 0.240 - 0.625 mg 1080/kg coyote | 5/6 coyotes died after eating squirrels contaminated with 1080 bait (sodium monofluroacetate) | Not Reported | Adult | 4-6/dose | 0.055 - 0.094 or 0.240-0.625 mg 1080/kg coyote; estimated doses of "low" or "high" contaminated ground squirrels | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
STRYCHNINE | increase @ 1.321 - 2.860 mg strychnine/kg coyote | 1/4 coyotes died after ingesting contaminated ground squirrels | Not Reported | Adult | 4/dose | 0.275-1.059 or 1.321-2.860 mg strychnine/kg coyote; estimated dose of "low" or "high" contaminated ground squirrels | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
PARA-AMINOPROPIOPHENONE | > 400 mg/kg | LD50 | Not Reported | Not Reported | 2/dose | 3 doses | TOX-MORT - toxicity benchmarks | single | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SODIUM MONOFLUOROACETATE | 182-1309 ppb wet wt. @ 0.8 mg/kg; 535-9754 ppb wet wt. @ 4.8 mg/kg | range of fluoroacetate residues in brain, caecum, kidney, liver, spleen, muscle and lung tissue of dead squirrels | Not Reported | Adult | 2/dose | 0, 0.8, 4.8 mg 1080/kg bw | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DIMETHOATE | 34% (27% SD) | mean reduction in blood serum cholinesterase activity compared to untreated | Male | Adult | Christmas tree farms; Sherbrooke, Quebec | 15-20 sparrows | 480 g active ingredient/litre | TOX-EXP IND - biomarkers | single | field application | Toxicity Factor Datasets |
DIAZINON | 27% (43% SD) | % reduction of blood serum cholinesterase compared to untreated | Not Reported | Not Reported | Christmas tree farms; Sherbrooke, Quebec | 20-29 sparrows | 500 g active ingredient/litre | TOX-EXP IND - biomarkers | single | field application | Toxicity Factor Datasets |