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Chemical | Endpoint Value | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
ALDRIN | increase at 0.1 and 0.5 lbs/acre | Not Reported | Tadpole | ponds, southern San Joaquin Valley | 10 animals/dose | 0.1, 0.5 lbs/acre | TOX-MORT - mortality in the field | single application | waterborne | Toxicity Factor Datasets |
TOXAPHENE (POLYCHLORINATED CAMPHENES) | increase at 0.5 lbs/acre | Not Reported | Tadpole | ponds, southern San Joaquin Valley | 10 animals/dose | 0.1, 0.5 lbs/acre | TOX-MORT - mortality in the field | single application | waterborne | Toxicity Factor Datasets |
LINDANE | increase at 0.5 lbs/acre | Not Reported | Tadpole | ponds, southern San Joaquin Valley | 10 animals/dose | 0.1, 0.5 lbs/acre | TOX-MORT - mortality in the field | single application | waterborne | Toxicity Factor Datasets |
HEPTACHLOR | increase at 0.5 lbs/acre | Not Reported | Tadpole | ponds, southern San Joaquin Valley | 10 animals/dose | 0.1, 0.5 lbs/acre | TOX-MORT - mortality in the field | single application | waterborne | Toxicity Factor Datasets |
ENDOSULFAN | increase at 0.1 and 0.5 lbs/acre | Not Reported | Tadpole | ponds, southern San Joaquin Valley | 10 animals/dose | 0.1, 0.5 lbs/acre | TOX-MORT - mortality in the field | single application | waterborne | Toxicity Factor Datasets |
CHLORDECONE (KEPONE) | no effect | Not Reported | Tadpole | ponds, southern San Joaquin Valley | 10 animals/dose | 0.1, 0.5 lbs/acre | TOX-MORT - mortality in the field | single application | waterborne | Toxicity Factor Datasets |
DDT (Technical Grade Mixture) | increase at 1.0 lbs/acre | Not Reported | Tadpole | ponds, southern San Joaquin Valley | 10 animals/dose | 0.1, 1.0 lbs/acre | TOX-MORT - mortality in the field | single application | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
ARSENIC COMPOUNDS, BARIUM COMPOUNDS, CADMIUM COMPOUNDS, CHROMIUM COMPOUNDS, COPPER COMPOUNDS, SELENIUM COMPOUNDS | increase | incidence of oral deformities at coal ash contaminated site, relative to reference site | Not Reported | Tadpole | Savannah River, Aiken | 575-1048 | mean whole body concn. at contaminated (C) compared to reference (R) site: As, C=48.9 +/- 2.6SE, R=2.5 +/-0.2SE; Ba, C=211.5 +/- 14.9SE, R=81.2 +/- 5.2SE; Cd, C=1.71 +/- 0.5SE, R=0.15 +/- 0.04SE; Cr, C=17.2 +/- 0.5SE, R=1.4 +/- 0.3SE; Cu, C=31.4 +/- 1.5SE | TOX-REPRO - development | NR | site contamination | Toxicity Factor Datasets |
ARSENIC COMPOUNDS, BARIUM COMPOUNDS, CADMIUM COMPOUNDS, CHROMIUM COMPOUNDS, COPPER COMPOUNDS, SELENIUM COMPOUNDS | increase at contaminated (C) compared to reference (R) site: Arsenic, C=48.9 +/- 2.6SE, R=2.5 +/-0.2SE; Barium, C=211.5 +/- 14.9SE, R=81.2 +/- 5.2SE; Cadmium, C=1.71 +/- 0.5SE, R=0.15 +/- 0.04SE; Chromium, C=17.2 +/- 0.5SE, R=1.4 +/- 0.3SE; Copper, C=31.4 +/- 1.5SE, R=17.5 +/- 6.6SE; Selenium, C=25.70 +/- 3.60SE, R=3.37 +/- 0.09SE. | mean whole body metal concentrations (ppm, dry mass) | Not Reported | Tadpole | Savannah River, Aiken | 3 animals/site | sediment concn. at contaminated (C) compared to reference (R) site: As, C=70.8 +/- 12.5SE, R=<1.0; Ba, C=418.7 +/- 34.0SE, R=11.8 +/- 0.6SE; Cd, C=0.57 +/- 0.05SE, R=0.03 +/- 0.00SE; Cr, C=70.8 +/- 12.5SE, R=<1.0; Cu, C=71.8 +/- 12.3SE, R=<1.0; Se, C=6.21 | TOX-EXP IND - accumulation | NR | site contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 34.4 ug/l (95% CL: 31.1 - 38.1 ug/l) | LC50 | Not Reported | Embryo | 20 animals/replicate; 4 replicates/dose | 0, 0.8, 2.0, 4.9, 11.0, 25.4, 64.8, 154.8 ug/l | TOX-MORT - toxicity benchmarks | 21 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 25.1 ug/l | LOAEL, based on mortality but gross spinal deformities also observed | Not Reported | Embryo | 20 animals/replicate; 4 replicates/dose | 0, 0.8, 2.0, 4.9, 11.0, 25.4, 64.8, 154.8 ug/l | TOX-MORT - toxicity benchmarks | 21 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 11.0 ug/l | NOAEL | Not Reported | Embryo | 20 animals/replicate; 4 replicates/dose | 0, 0.8, 2.0, 4.9, 11.0, 25.4, 64.8, 154.8 ug/l | TOX-MORT - toxicity benchmarks | 21 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 8.7 ug/l (95% CL: 7.8-9.7 ug/l) | LC50 | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l | TOX-MORT - toxicity benchmarks | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 11.2 ug/l | LOAEL | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l | TOX-MORT - toxicity benchmarks | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 4.0 ug/l | NOAEL | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l | TOX-MORT - toxicity benchmarks | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 5.1 ug/g at 8.7 ug/l | whole body dieldrin concentration (ug/g, wet wt.) at the LC50 | Not Reported | Tadpole | Not Reported | 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l | TOX-EXP IND - accumulation | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 6.0 ug/g at 11.2 ug/l | whole body dieldrin concentration (ug/g, wet wt.) | Not Reported | Tadpole | Not Reported | 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l | TOX-EXP IND - accumulation | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 2.0 ug/g at 4.0 ug/l | whole body dieldrin concentration (ug/g, wet wt.) | Not Reported | Tadpole | Not Reported | 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l | TOX-EXP IND - accumulation | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 360 - 540 | range of bioconcentration factors; calculated by dividing the whole body tissue dieldrin concentration by water dieldrin concentration | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l | TOX-EXP IND - accumulation | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 36,000 - 54,000 | range of lipid bioconcentration factors; calculated by dividing the whole body bioconcentration values x 100 by percent lipid | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l | TOX-EXP IND - accumulation | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 30.3 ug/l (95% CL: 26.2 - 35.2 ug/l) | LC50 | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l | TOX-MORT - toxicity benchmarks | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 52.3 ug/l | LOAEL | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l | TOX-MORT - toxicity benchmarks | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 12.3 ug/l | NOAEL | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l | TOX-MORT - toxicity benchmarks | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 12.0 ug/g at 30.3 ug/l | whole body dieldrin concentration (ug/g, wet wt.) at the LC50 | Not Reported | Tadpole | Not Reported | 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l | TOX-EXP IND - accumulation | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 19.0 ug/g at 52.3 ug/l | whole body dieldrin concentration (ug/g, wet wt.) | Not Reported | Tadpole | Not Reported | 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l | TOX-EXP IND - accumulation | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 0.5 ug/g at 12.3 ug/l | whole body dieldrin concentration (ug/g, wet wt.) at the NOAEL | Not Reported | Tadpole | Not Reported | 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l | TOX-EXP IND - accumulation | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 360 - 900 | range of bioconcentration factors; calculated by dividing the whole body tissue dieldrin concentration by water dieldrin concentration | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l | TOX-EXP IND - accumulation | 4 d | waterborne | Toxicity Factor Datasets |
DIELDRIN | 36,000 - 90,000 | range of lipid bioconcentration factors; calculated by dividing the whole body bioconcentration values x 100 by percent lipid | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l | TOX-EXP IND - accumulation | 4 d | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD NITRATE | no effect | preference/avoidance behavior and spontaneous locomotor activity | Not Reported | Tadpole | 8 animals/dose | 0, 500, 625, 750, 1000 ug/l | TOX-REPRO - behavior | 6 d | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
MEXACARBATE | 283 - 800 mg/kg | LD50, estimated | Male | Not Reported | 14 | NR | TOX-MORT - toxicity benchmarks | single | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
TRIFLUOROMETHYL-4-NITROPHENOL (3-, LAMPRECIDE) | 11.62 mg/kg bw (95% CL: 10.71-13.14) | LD50 | Not Reported | Tadpole | 5 | NR | TOX-MORT - toxicity benchmarks | single | intraperitoneal | Toxicity Factor Datasets |
TRIFLUOROMETHYL-4-NITROPHENOL (3-, LAMPRECIDE) | 15.35 mg/kg bw (95% CL: 8.72-21.98) | LD50 | Not Reported | Adult | 7 | NR | TOX-MORT - toxicity benchmarks | single | intraperitoneal | Toxicity Factor Datasets |
TRIFLUOROMETHYL-4-NITROPHENOL (3-, LAMPRECIDE) | 0.95 mg/l (95% CL: 0.72 - 1.14) | LC50 | Not Reported | Tadpole | 5 | NR | TOX-MORT - toxicity benchmarks | 24 hr | waterborne | Toxicity Factor Datasets |
TRIFLUOROMETHYL-4-NITROPHENOL (3-, LAMPRECIDE) | 12.99 mg/l (95% CL: 6.75 - 19.22) | LC50 | Not Reported | Adult | 7 | NR | TOX-MORT - toxicity benchmarks | 24 hr | waterborne | Toxicity Factor Datasets |
TRIFLUOROMETHYL-4-NITROPHENOL (3-, LAMPRECIDE) | effect observed at 1.0 - 3.0 mg/l | growth development arrested | Not Reported | Embryo | Not Reported | 0.1, 0.25, 0.5, 1.0, 2.0, 3.0 mg/l | TOX-REPRO - development | 96 hr | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
FENTHION | decrease @ 60 ppb | temperature tolerance, estimated by heating water at 1C/3min and using onset of spasms in frogs as the endpoint | Not Reported | Juvenile | 10 animals/replicate; 2 replicates/dose | 0, 30, 60 ppb | TOX-Non-Repro-Sublethal - whole animal | 24 hr | waterborne | Toxicity Factor Datasets |
CHLORPYRIFOS | decrease @ 30 and 60 ppb | temperature tolerance, estimated by heating water at 1C/3min and using onset of spasms in frogs as the endpoint | Not Reported | Juvenile | 10 animals/replicate; 2 replicates/dose | 0, 30, 60 ppb | TOX-Non-Repro-Sublethal - whole animal | 24 hr | waterborne | Toxicity Factor Datasets |
METHYLPARATHION | decrease @ 25 and 50 ppb | temperature tolerance, estimated by heating water at 1C/3min and using onset of spasms in frogs as the endpoint | Not Reported | Juvenile | 10 animals/replicate; 2 replicates/dose | 0, 25, 50 ppb | TOX-Non-Repro-Sublethal - whole animal | 24 hr | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
ZINC SULFATE | increase @ 39 mg/l | 100% mortality reported | Not Reported | Juvenile | 5-25/dose | 0, 0.1, 39 mg/l Zn++ | TOX-MORT - dose-response data | 61 d | waterborne | Toxicity Factor Datasets |
COPPER SULFATE | increase @ 3.7 mg/l | 100% mortality reported | Not Reported | Juvenile | 5-25/dose | 0, 0.02, 3.7 mg/l Cu++ | TOX-MORT - dose-response data | 61 d | waterborne | Toxicity Factor Datasets |