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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN | 622.0 (DDE), 25.4 (DDD), 25.3 (DDT), 6.20 (dieldrin) | mean concentrations of pesticides in fat (ppm, dry weight) | Both Male and Female | Adult | Yukon River | 4 birds | range of mean concentrations in prey items, ppm dry wt: 0.32-6.02 (DDE), 0.07-0.17 (DDD), 0.09-0.19 (DDT), 0.00-0.11 (dieldrin) | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 6.4-33 ppm, dry wt | range of concentrations in whole addled eggs | Female | Adult | 5 eggs from 3 clutches | 0.01-8.78 ppm, wet wt, in composite prey samples | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
DDE (4,4'-) | 14.2% | percent eggshell thinning compared to pre-1947 reference eggs | Female | Adult | 26 breeding attempts | 0.01-8.78 ppm, wet wt, in composite prey samples | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
HEPTACHLOR EPOXIDE | negative correlation | correlation of heptachlor epoxide concentration in eggs and eggshell thickness | Female | Adult | 38 eggs | 0.10-1.10 ppm, wet wt, in eggs | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
DDE (4,4'-) | 21:0.09 | ratio of average concentration of DDE in eggs to average concentration of DDE in prey items | Female | Adult | 12 prey species, pooled samples of 7-10 individuals | range of mean concentrations in prey species: 0.04-6.0 ppm, wet wt | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | eggshell thickness index = 1.799 - 0.243(log DDE) | linear regression of eggshell thickness index vs. log DDE concentration in eggs | Female | Adult | 295 eggs | range of mean concentrations in eggs: 0.58-15.19 ppm, wet wt | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
MERCURY (elemental) | brood size = 0.848 - 0.635(log DDE) - 0.271(log Hg) | linear regression of brood size vs mercury and DDE concentrations in eggs | Female | Adult | 60 eggs | range of geometric mean concentrations in eggs: 0.21-1.27 ppm, dry wt | TOX-REPRO - reproductive success | NR | environmental contamination | Toxicity Factor Datasets |
DDE (4,4'-) | productivity = 1.412 - 0.724(log DDE) | linear regression of productivity (mean number of young raised per pair) vs. log DDE concentration in eggs | Both Male and Female | Adult | 14 pairs | range of mean concentrations in eggs: 0.58-15.19 ppm, wet wt | TOX-REPRO - reproductive success | NR | environmental contamination | Toxicity Factor Datasets |
DDE (4,4'-), HEPTACHLOR EPOXIDE | 15 ppm DDE, 0.7 ppm heptachlor epoxide | concentrations in eggs associated with population recovery | Both Male and Female | Both Adults and Juveniles | 550 eggs from 469 clutches | range of mean concentrations in eggs, ppm, wet wt: 0.58-15.19 (DDE); 0.01 - 0.77 (heptachlor epoxide) | TOX-POP - size effects | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-), POLYCHLORINATED BIPHENYLS | 11.4% | percent eggshell thinning compared to pre-DDT reference eggs | Female | Adult | Kola Peninsula | 8 nests | geom. mean concentrations in eggs, ppm, wet wt: 3.5 (DDE), 7.3 (PCBs), wet wt, in eggs (geometric means) | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
MERCURY (elemental) | 2.80 - 10.60 ppm, dry wt (females) 3.70 - 8.95 ppm, dry wt (males) | range of concentrations measured in primary and rectrix feathers | Both Male and Female | Adult | Southern Sweden | 3 sample periods; 1-9 birds/sample period | < 0.1 to between 0.1 and 0.2 ppm, wet wt, in pectoral muscles of avian prey species | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
MERCURY (elemental) | 6.90-29.50 ppm, dry wt (females) 12.10 ppm, dry wt (males) | concentrations measured in primary and rectrix feathers | Both Male and Female | Adult | Northern Sweden | 20 females, 1 male | < 0.1 to >0.4 ppm, wet wt, in pectoral muscles of avian prey species | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
MERCURY (elemental) | 2.79 (3.10) ppm, dry wt | mean (SD) concentration measured in feathers | Not Reported | Juvenile | Southern Sweden | 3 nests | < 0.1 to between 0.1 and 0.2 ppm, wet wt, in pectoral muscles of avian prey species | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
MERCURY (elemental) | 8.31(2.59) ppm, dry wt | mean (SD) concentration measured in feathers | Not Reported | Juvenile | Northern Sweden | 3 nests | < 0.1 to >0.4 ppm, wet wt, in pectoral muscles of avian prey species | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 16% | percent eggshell thinning compared to pre-1947 reference eggs | Female | Adult | South Australia | 13 eggs | 3.98 ppm, wet wt, in eggs | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | eggshell thickness index = 1.888 - 0.281(log DDE) | linear regression of eggshell thickness index and DDE content of eggs | Female | Adult | Tasmania, Victoria, South Australia | 137 eggs | 1.8-12.4 ppm, wet wt, in eggs (range of geometric means) | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
DDE (4,4'-) | productivity = 1.79 - 0.04(DDE) | linear regression of productivity (number of young fledged per site) and DDE concentrations in eggs | Both Male and Female | Adult | Tasmania | 9 eggs | range of geometric means, ppm, wet wt: 2.0-6.1 (eggs); 0.06 - 1.78 (typical prey items) | TOX-REPRO - reproductive success | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | review | data correlating eggshell thinning and DDE concentrations in eggs | Female | Adult | Not Reported | NR | TOX-REPRO - physiology | NR | NR | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no relation | linear regression of eggshell thickness and DDE concentration in eggs | Female | Adult | Victoria | 35 eggs | range of concentrations, ppm, wet wt: 2.30 to 82.00 (eggs); negligible to 0.74 (representative prey species) | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | eggshell thickness compared to pre-1947 reference eggs | Female | Adult | 2 eggs, 1 nest | 0.69-1.40 ppm, wet wt, in eggs | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
FENTHION | increased @ all doses | mortality versus controls | Both Male and Female | Adult | 8 | 0,23.6,47.2,94.5,189.0 ppm in diet | TOX-MORT - dose-response data | 1 d | diet | Toxicity Factor Datasets |
CARBOFURAN | increased at 63.4, 126.8, 253.6 ppm | mortality versus controls | Both Male and Female | Adult | 8 | 0,31.7,63.4,126.8,253.6 ppm in diet | TOX-MORT - dose-response data | 1 d | diet | Toxicity Factor Datasets |
FENTHION | decreased to 10% of control levels | brain cholinesterase activity of birds that died | Both Male and Female | Adult | 8 | 0,23.6,47.2,94.5,189.0 ppm in diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 1 d | diet | Toxicity Factor Datasets |
CARBOFURAN | decreased to 35% of controls | brain cholinesterase activity in birds that died | Both Male and Female | Adult | 8 | 0,31.7,63.4,126.8,253.6 ppm in diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 1 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | Y=1.132 + 0.801X (R^2 = 0.932) | relationship between Se concentrations in diet and blood | Both Male and Female | Adult | 9-10 pairs/group | 0,5,9 ppm, dry wt, in diet | TOX-EXP IND - accumulation | 77 d | diet | Toxicity Factor Datasets |
SELENIUM COMPOUNDS | 7.5 ppm Se, dry wt | maximum observed Se concentration in blood | Both Male and Female | Adult | 10 pairs/group | 8 ppm, dry wt, in contaminated prey species | TOX-EXP IND - accumulation | 77 d | diet | Toxicity Factor Datasets |
SELENOMETHIONINE | no effect | incidence of mortality or signs of toxicity | Both Male and Female | Adult | 9-10 pairs/group | 0,5,9 ppm, dry wt, in diet | TOX-MORT - dose-response data | 77 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DICOFOL | decreased 5.45% (@ 5 mg/kg), 10.98% (@ 20 mg/kg) | eggshell thickness compared to controls | Female | Adult | 10/group | 0,5,20 mg/kg bw | TOX-REPRO - physiology | daily, throughout breeding season | gavage | Toxicity Factor Datasets |
DICOFOL | non-detectable (@ 5 mg/kg), 560 ng/g (@ 20 mg/kg) | mean concentration of metabolite dichlorobenzophenone in eggs | Female | Adult | 10/group | 0,5,20 mg/kg bw | TOX-EXP IND - accumulation | daily, throughout breeding season | gavage | Toxicity Factor Datasets |
DICOFOL | increased @ 5 and 20 mg/kg | incidence of abnormal embyronic gonads | Both Male and Female | Embryo | 10/group | 0,5,20 mg/kg bw | TOX-REPRO - development | daily, throughout breeding season | gavage | Toxicity Factor Datasets |
DICOFOL | increased @ 5 mg/kg | numbers of chicks or eggs lost (destroyed) by breeding male and female offspring of dicofol-treated females versus controls | Female | Adult | 10/group | 0,5,20 mg/kg bw | TOX-REPRO - development | daily, throughout breeding season | gavage | Toxicity Factor Datasets |
DICOFOL | no effect | eggshell thickness for breeding female offspring of dicofol-treated females versus controls | Female | Adult | 10/group | 0,5,20 mg/kg bw | TOX-REPRO - physiology | daily, throughout breeding season | gavage | Toxicity Factor Datasets |
DICOFOL | increased @ 5 mg/kg bw | incidence of abnormal gonads in male offspring of dicofol-treated females versus controls | Male | Adult | 10/group | 0,5,20 mg/kg bw | TOX-REPRO - development | daily, throughout breeding season | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DICOFOL | increased | incidence of abnormal behavior in adult offspring of treated females | Both Male and Female | Adult | 10 pairs/group | 0,5,20 mg/kg bw | TOX-REPRO - behavior | daily, throughout the breeding season | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | decreased @ 250, 1000 ng/g bw | body and organ growth versus controls | Not Reported | Nestling | 9-11/group | 0,50,250,1000 g/ng bw | TOX-Non-Repro-Sublethal - whole animal | 10 d | gavage | Toxicity Factor Datasets |
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | increased @ 50,250,1000 ng/g bw | incidence and severity of lesions in liver, spleen, bursa, thyroid versus controls | Not Reported | Nestling | 9-11/group | 0,50,250,1000 g/ng bw | TOX-Non-Repro-Sublethal - organ/system effects | 10 d | gavage | Toxicity Factor Datasets |
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | increased | plasma enzyme activities indicative of hepatotoxicity versus controls | Not Reported | Nestling | 9-11/group | 0,50,250,1000 g/ng bw | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 10 d | gavage | Toxicity Factor Datasets |
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | no effect | hematocrit and hemoglobin values versus controls | Not Reported | Nestling | 9-11/group | 0,50,250,1000 g/ng bw | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 10 d | gavage | Toxicity Factor Datasets |
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | increased @ 50,250,1000 ng/g bw | hepatic monooxygenase activities versus controls | Not Reported | Nestling | 9-11/group | 0,50,250,1000 g/ng bw | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 10 d | gavage | Toxicity Factor Datasets |
PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) | in ng/g, wet wt: 156 (@ 50 ng/g), 380 (@ 250 ng/g), 1098 (@1000 ng/g) | concentration in liver | Not Reported | Nestling | 9-11/group | 0,50,250,1000 g/ng bw | TOX-EXP IND - accumulation | 10 d | gavage | Toxicity Factor Datasets |