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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
PCB 77 (3,3',4,4'-TETRACHLOROBIPHENYL) | increased @ 100, 1000 ng/g | incidence of malformations or edema, and EROD activity versus controls | Not Reported | Hatchling | 24-26/treatment group | 0, 100, 1000 ng/g egg weight | TOX-REPRO - development | single dose at incubation day 6 | egg injection | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254, PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL), PCB 77 (3,3',4,4'-TETRACHLOROBIPHENYL) | increased with PCB 77 | liver weight (as percent of body weight) versus controls | Female | Adult | 4/treatment group | 0; 250 mg/kg bw (PCB 77 or PCB 153); 25 mg/kg bw (PCB 126); 100, 250 or 500 mg/kg bw (Aroclor 1254) | TOX-Non-Repro-Sublethal - organ/system effects | single | oral gavage | Toxicity Factor Datasets |
AROCLOR 1254, PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL), PCB 77 (3,3',4,4'-TETRACHLOROBIPHENYL) | increased with Aroclor 1254 | coproporphyrin levels in liver versus controls | Female | Adult | 4/treatment group | 0; 250 mg/kg bw (PCB 77 or PCB 153); 25 mg/kg bw (PCB 126); 100, 250 or 500 mg/kg bw (Aroclor 1254) | TOX-Non-Repro-Sublethal - organ/system effects | single | oral gavage | Toxicity Factor Datasets |
AROCLOR 1254, PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL), PCB 77 (3,3',4,4'-TETRACHLOROBIPHENYL) | increased with PCB 77 | liver ethoxyresorufin-O-deethylase activity versus controls | Female | Adult | 4/treatment group | 0; 250 mg/kg bw (PCB 77 or PCB 153); 25 mg/kg bw (PCB 126); 100, 250 or 500 mg/kg bw (Aroclor 1254) | TOX-Non-Repro-Sublethal - organ/system effects | single | oral gavage | Toxicity Factor Datasets |
AROCLOR 1254, PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL), PCB 77 (3,3',4,4'-TETRACHLOROBIPHENYL) | decreased with PCB 153 | liver ethoxyresorufin-O-deethylase activity versus controls | Female | Adult | 4/treatment group | 0; 250 mg/kg bw (PCB 77 or PCB 153); 25 mg/kg bw (PCB 126); 100, 250 or 500 mg/kg bw (Aroclor 1254) | TOX-Non-Repro-Sublethal - organ/system effects | single | oral gavage | Toxicity Factor Datasets |
AROCLOR 1254, PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL), PCB 153 (2,2',4,4',5,5'-HEXACHLOROBIPHENYL), PCB 77 (3,3',4,4'-TETRACHLOROBIPHENYL) | increased with PCB 126 | liver ethoxyresorufin-O-deethylase activity versus controls | Female | Adult | 4/treatment group | 0; 250 mg/kg bw (PCB 77 or PCB 153); 25 mg/kg bw (PCB 126); 100, 250 or 500 mg/kg bw (Aroclor 1254) | TOX-Non-Repro-Sublethal - organ/system effects | single | oral gavage | Toxicity Factor Datasets |
AROCLOR 1254 | increased after 4 or 12 weeks | aminopyrine N-demethylase and aldrin epoxidase activities versus controls | Female | Adult | 4/treatment group | 0, 7 mg/kg/d | TOX-Non-Repro-Sublethal - organ/system effects | daily for 4, 8 or 12 weeks | oral gavage | Toxicity Factor Datasets |
AROCLOR 1254 | decreased after 4 weeks | liver ethoxyresorufin-O-deethylase activity versus controls | Female | Adult | 4/treatment group | 0, 7 mg/kg/d | TOX-Non-Repro-Sublethal - organ/system effects | daily for 4, 8 or 12 weeks | oral gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | blood Se concentration = 1.307 + 0.852(diet Se concentration) | relation between Se concentrations in blood (dry wt) and diet (dry wt) | Male | Adult | 40 birds | 0,6, 12 ppm, dry wt, Se in diet | TOX-EXP IND - accumulation | 11 wks | diet | Toxicity Factor Datasets |
SELENOMETHIONINE | egg Se concentration = 1.307 + 0.852(diet Se concentration) | relation between Se concentrations in egg (dry wt) and diet (dry wt) | Female | Adult | 53 eggs | 0,6, 12 ppm, dry wt, Se in diet | TOX-EXP IND - accumulation | 11 wks | diet | Toxicity Factor Datasets |
SELENOMETHIONINE | increased @ 6 or 12 ppm Se | food consumption versus controls | Both Male and Female | Adult | 15 pairs/treatment group; 10 control pairs | 0,6, 12 ppm, dry wt, Se in diet | TOX-Non-Repro-Sublethal - behavioral effects | 11 wks | diet | Toxicity Factor Datasets |
SELENOMETHIONINE | no effect | percent of pairs that laid eggs, number of fertile pairs and egg hatchability versus controls | Both Male and Female | Adult | 15 pairs/treatment group; 10 control pairs | 0,6, 12 ppm, dry wt, Se in diet | TOX-REPRO - reproductive success | 11 wks | diet | Toxicity Factor Datasets |
SELENOMETHIONINE | no effect | egg mass, width, length, and volume versus controls | Both Male and Female | Adult | 15 pairs/treatment group; 10 control pairs | 0,6, 12 ppm, dry wt, Se in diet | TOX-REPRO - physiology | 11 wks | diet | Toxicity Factor Datasets |
SELENOMETHIONINE | reduced @ 12 ppm Se | ratio of # fertile eggs to total # eggs laid versus 6 ppm Se group | Both Male and Female | Adult | 15 pairs/treatment group; 10 control pairs | 0,6, 12 ppm, dry wt, Se in diet | TOX-REPRO - reproductive success | 11 wks | diet | Toxicity Factor Datasets |
SELENOMETHIONINE | no effect | incidence of embryo deformities versus controls | Both Male and Female | Adult | 15 pairs/treatment group; 10 control pairs | 0,6, 12 ppm, dry wt, Se in diet | TOX-REPRO - development | 11 wks | diet | Toxicity Factor Datasets |
SELENOMETHIONINE | no effect | chick mass and size at hatch, and chick survival to fledging versus controls | Both Male and Female | Adult, Juvenile | 15 pairs/treatment group; 10 control pairs | 0,6, 12 ppm, dry wt, Se in diet | TOX-REPRO - development | 11 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Toxicity Endpoint Type | Type |
---|---|---|---|
CARBARYL, CARBOFURAN, DDE (4,4'-) | review | TOX-REPRO - reproductive success | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Toxicity Endpoint Type | Type |
---|---|---|---|---|---|---|
ALDRIN, BRODIFACOUM, CARBOFURAN, CHLORDANE, DIELDRIN, ENDRIN, FAMPHUR, FENTHION, PHORATE, STRYCHNINE | review | summaries of mortality due to organochlorine, anticholinesterase, anticoagulant, strychnine pesticides | Not Reported | Not Reported | TOX-MORT - mortality in the field | Toxicity Factor Datasets |
STRYCHNINE, ZINC PHOSPHIDE | review | summaries of sublethal effects due to organochlorine, anticholinesterase, anticoagulant, strychnine pesticides | Not Reported | Not Reported | TOX-Non-Repro-Sublethal - whole animal | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | productivity in contaminated versus uncontaminated sites | Both Male and Female | Adult | Rocky Mountain Arsenal National Wildlife Refuge | 3-4 nests on contaminated sites; 5-9 nests on uncontaminated sites | 0.18 ppm (uncontaminated), 1.15 ppm (contaminated) in soil within adult home ranges | TOX-REPRO - reproductive success | NR | habitat contamination | Toxicity Factor Datasets |
DIELDRIN | negative correlation | relationship between residue in plasma and survival | Not Reported | Juvenile | Rocky Mountain Arsenal National Wildlife Refuge | 6 birds (contaminated sites), 10 birds (uncontaminated sites) | 0.01 ppm (uncontaminated), 0.22 ppm (contaminated) in plasma | TOX-MORT - mortality in the field | NR | habitat contamination | Toxicity Factor Datasets |
DIELDRIN | no effect | daily and interval survival estimates on uncontaminated versus contaminated sites | Not Reported | Juvenile | Rocky Mountain Arsenal National Wildlife Refuge | 14 birds on contaminated sites; 41 birds on uncontaminated sites | 0.18 ppm (uncontaminated), 1.15 ppm (contaminated) in soil within adult home ranges | TOX-MORT - mortality in the field | NR | habitat contamination | Toxicity Factor Datasets |
DIELDRIN | no effect | daily survival rates on uncontaminated versus contaminated sites | Not Reported | Adult | Rocky Mountain Arsenal National Wildlife Refuge | 9 birds on contaminated sites; 11 birds on uncontaminated sites | 0.18 ppm (uncontaminated), 1.15 ppm (contaminated) in soil within adult home ranges | TOX-MORT - mortality in the field | NR | habitat contamination | Toxicity Factor Datasets |
DIELDRIN | 0.07 +/- 0.03 ppm (uncontaminated site); 0.34 +/- 0.21 ppm (contaminated site) | mean (+/- SE) concentrations in plasma | Not Reported | Adult | Rocky Mountain Arsenal National Wildlife Refuge | 2 birds on contaminated sites; 5 birds on uncontaminated sites | 0.18 ppm (uncontaminated), 1.15 ppm (contaminated) in soil within adult home ranges | TOX-EXP IND - accumulation | NR | habitat contamination | Toxicity Factor Datasets |
DIELDRIN | 0.01 +/- 0.003 ppm (uncontaminated site); 0.22 +/- 0.03 ppm (contaminated site) | mean (+/- SE) concentrations in plasma | Not Reported | Juvenile | Rocky Mountain Arsenal National Wildlife Refuge | 6 birds on contaminated sites; 10 birds on uncontaminated sites | 0.18 ppm (uncontaminated), 1.15 ppm (contaminated) in soil within adult home ranges | TOX-EXP IND - accumulation | NR | habitat contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Toxicity Endpoint Type | Type |
---|---|---|---|
DIELDRIN | review | TOX-MORT - dose-response data | Toxicity Factor Datasets |