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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CHLOROPHACINONE | 99 ug | total carcass residues 28 d after removal from treatment | Not Reported | Adult | 1 owl | 3.2 ppm in voles maintained on treated food | TOX-EXP IND - accumulation | 6 d | diet | Toxicity Factor Datasets |
CHLOROPHACINONE | no effect | occurence of external bleeding or internal abnormalities after removal from treated diet | Not Reported | Adult | 1 owl | 3.2 ppm in voles maintained on treated food | TOX-Non-Repro-Sublethal - whole animal | 6 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIPHACINONE | 4.1-5.5 mg | doses resulting in symptoms and death in 2/3 birds within 14 days | Not Reported | Adult | 3 owls | 4.1-5.5 mg total consumed in mice fed a 0.01% bait | TOX-MORT - toxicity benchmarks | 5 days | diet | Toxicity Factor Datasets |
DIPHACINONE | increased | time to coagulation in blood sampled 3 days after treatment ended | Not Reported | Adult | 3 owls | 4.1-5.5 mg total consumed in mice fed a 0.01% bait | TOX-Non-Repro-Sublethal - organ/system effects | 5 days | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
STRYCHNINE | increased | occurence (compared with pre-dose values) of uncoordinated movement, tremors, loss of perching ability and ability to stand on the ground | Not Reported | Adult | 1 bird | 1.8 mg injected into mouse | TOX-Non-Repro-Sublethal - behavioral effects | single exposure | diet | Toxicity Factor Datasets |
STRYCHNINE | increased | occurence (compared with pre-dose values) of uncoordinated movement, tremors, loss of perching ability and ability to stand on the ground | Not Reported | Adult | 1 bird | 1.0 mg injected into mouse | TOX-Non-Repro-Sublethal - behavioral effects | single exposure | diet | Toxicity Factor Datasets |
STRYCHNINE | increased | occurence of errors (compared with pre-test values) in a reversal learning test | Not Reported | Adult | 1 bird | 0.4 mg injected into mouse | TOX-Non-Repro-Sublethal - behavioral effects | single exposure | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
ENDRIN | breast muscle=0.02 ppm, wet wt | tissue endrin residues | Not Reported | Not Reported | Wenatchee | 1 animal | 1.3-1.7 kg/ha | TOX-EXP IND - accumulation | NR | pesticide application (late fall) | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | 293.43-820.93 ppm, lipid weight | concentrations of DDT, DDE, DDD (combined) in skin and brains, 2 years post-application | Not Reported | Not Reported | 3.2 km NE of Davis | 2 birds | 0.22 kg DDT/ha | TOX-EXP IND - accumulation | 1 application | experimental application | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | see figure | figure showing concentration of DDT and metabolites in skin and brains before and after application | Not Reported | Not Reported | 3.2 km NE of Davis | 27 birds (3-4/sampling time) | 0.22 kg DDT/ha | TOX-EXP IND - accumulation | 1 application | experimental application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DIELDRIN | increased at 1 mg/kg | latency to formation of natural prey killing behaviors | Not Reported | Juvenile | collected in San Diego County, CA | 10-11/dose | 0, 1 mg/kg bw/d (87% active ingredient) | TOX-Non-Repro-Sublethal - behavioral effects | until death (max. 103 d) | gavage | Toxicity Factor Datasets |
DIELDRIN | increased at 1, 2, 4, 8 mg/kg/d | rate of mortality compared with controls | Not Reported | Juvenile | collected in San Diego County, CA | 10-11/dose | 0, 1, 2, 4, 8 mg/kg bw/d (87% active ingredient) | TOX-MORT - dose-response data | until death (max. 103 d) | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 3.09 (0.09 SE) ppm, wet wt | concentration in eggs | Not Reported | Embryo | southern IL | 20 clutches, 104 eggs | 21.04 (3.51 SE) ppm in fat of adult females | TOX-EXP IND - accumulation | NR | parental transfer | Toxicity Factor Datasets |
DDE (4,4'-) | decreased | eggshell thickness index compared with reference samples collected in 1875-95 | Not Reported | Embryo | southern IL | 20 clutches, 104 eggs | 21.04 (3.51 SE) ppm in fat of adult females | TOX-REPRO - physiology | NR | parental transfer | Toxicity Factor Datasets |
DDE (4,4'-) | y = 92.610 - 2.412 log x | linear negative correlation of egg DDE concentration and shell thickness | Not Reported | Embryo | southern IL | 20 clutches, 104 eggs | 21.04 (3.51 SE) ppm in fat of adult females | TOX-REPRO - physiology | NR | parental transfer | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
AMMONIUM NITRATE | significantly increased (138.5% +/- 86.1 SD) | percent increase in breeding territory size post-spray vs. unsprayed controls | Both Male and Female | Both Adults and Juveniles | MacArthur Agroecology Research Center, Archbold Biological Station | 4 control, 8 treatment territories | 54 kg/ha application rate | TOX-Non-Repro-Sublethal - indirect effects | approx. 1 month | application to habitat | Toxicity Factor Datasets |
AMMONIUM NITRATE | significantly earlier | timing of nesting season termination in pairs post-spray vs. unsprayed controls | Both Male and Female | Both Adults and Juveniles | MacArthur Agroecology Research Center, Archbold Biological Station | 4 control, 8 treatment territories | 54 kg/ha application rate | TOX-Non-Repro-Sublethal - indirect effects | approx. 1 month | application to habitat | Toxicity Factor Datasets |
AMMONIUM NITRATE | increased | loss of eggs, nestlings, fledglings and adults post-spray vs. unsprayed controls | Both Male and Female | Both Adults and Juveniles | MacArthur Agroecology Research Center, Archbold Biological Station | 4 control, 8 treatment territories | 54 kg/ha application rate | TOX-Non-Repro-Sublethal - indirect effects | approx. 1 month | application to habitat | Toxicity Factor Datasets |
Chemical | Endpoint Value | Toxicity Endpoint Type | Type |
---|---|---|---|
POLYCHLORINATED BIPHENYLS | review | TOX-Non-Repro-Sublethal - cellular/biochemical effects | Toxicity Factor Datasets |
POLYCHLORINATED BIPHENYLS | review | TOX-MORT - toxicity benchmarks | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
POLYCHLORINATED BIPHENYLS | see figures | figure for each dose, showing metabolic rate at increasing ambient temperatures | Not Reported | Adult | 10 birds/group | 0, 1, 3, 9 ppm (dry wt) in food | TOX-Non-Repro-Sublethal - organ/system effects | 10 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
ALDRIN, DIELDRIN | <0.1 ppm aldrin, 3.8 ppm dieldrin, 0.3 ppm DDT and metabolites, wet wt | post-mortem whole body concentrations | Not Reported | Not Reported | 1 bird | 4 oz aldrin/100 lbs seeds | TOX-EXP IND - accumulation | NR | pesticide application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
ALDRIN | 15-17 mg/kg | median lethal dosage | Not Reported | Not Reported | 21 birds | NR | TOX-MORT - toxicity benchmarks | single | oral | Toxicity Factor Datasets |
DIELDRIN | 44-46 mg/kg | median lethal dosage | Not Reported | Not Reported | 20 birds | NR | TOX-MORT - toxicity benchmarks | single | oral | Toxicity Factor Datasets |
TOXAPHENE (POLYCHLORINATED CAMPHENES) | 200-250 mg/kg | approximate median lethal dosage | Not Reported | Not Reported | 8 birds | NR | TOX-MORT - mortality in the field | single | oral | Toxicity Factor Datasets |
LINDANE | 350-400 mg/kg | approximate median lethal dosage | Not Reported | Not Reported | 21 birds | NR | TOX-MORT - toxicity benchmarks | single | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
CESIUM COMPOUNDS | 0.24 (0.027 SE) Bq/g, wet weight (whole body) 0.30 (0.036 SE) Bq/g, wet weight (muscle) | whole body and muscle concentrations of 137Cesium | Both Male and Female | Both Adults and Juveniles | Par Pond reservoir system, Savannah River Site | 27 doves | 0.56 (0.065 SE) Bq/g, wet wt, ingesta | TOX-EXP IND - accumulation | NR | diet (via site contamination) | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DIMETHOATE | 34% (27% SD) | mean reduction in blood serum cholinesterase activity compared to untreated | Male | Adult | Christmas tree farms; Sherbrooke, Quebec | 15-20 sparrows | 480 g active ingredient/litre | TOX-EXP IND - biomarkers | single | field application | Toxicity Factor Datasets |
DIAZINON | 27% (43% SD) | % reduction of blood serum cholinesterase compared to untreated | Not Reported | Not Reported | Christmas tree farms; Sherbrooke, Quebec | 20-29 sparrows | 500 g active ingredient/litre | TOX-EXP IND - biomarkers | single | field application | Toxicity Factor Datasets |
DIAZINON | 38% | mortality of eggs and nestlings (control 21 %) | Not Reported | Embryo, Nestling | Sherbrooke, Quebec | 9 nests | 500 g active ingred/litre | TOX-MORT - mortality in the field | single | field application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Units | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DIMETHOATE | significant reduction of mean daily activity levels (perch hopping) | Not Reported | Not Reported | 7 treated; 7 control | average food intake 2.14 g (0.48SE)/d ; 0.24 g Dimethoate sprayed over 1 m2 seeds; | TOX-Non-Repro-Sublethal - behavioral effects | single; (1 seed lot0 | diet | Toxicity Factor Datasets | ||
DIMETHOATE | 3.4 | weight loss (3.4 g over experiment period; controls gained 0.43 g) | g | Not Reported | Not Reported | 7 treated; 7 control | 0.24 g Dimethoate sprayed over 1 m2 seeds | TOX-Non-Repro-Sublethal - indirect effects | single; (1 seed lot0 | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
ALDRIN, DIELDRIN | 6.1 ppm (brain), 10.7 ppm (body remainder) dieldrin, wet wt | post-mortem concentrations | Not Reported | Not Reported | 1 bird | 4 oz aldrin/100 lbs seeds | TOX-EXP IND - accumulation | NR | pesticide application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
ENDRIN | brain=greater than or equal to 0.8 ppm, wet wt | tissue endrin residues | Not Reported | Not Reported | Wenatchee | 1-3 animals | 1.3-1.7 kg/ha | TOX-EXP IND - accumulation | NR | pesticide application (late fall) | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | review | concentrations of chemicals in eggs and diet associated with mortality and eggshell thinning (various raptor species) | Not Reported | Adult | Not Reported | NR | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
DIELDRIN | review | concentrations in brain associated with mortality (various raptor species) | Not Reported | Not Reported | Not Reported | NR | TOX-MORT - dose-response data | NR | environmental contamination | Toxicity Factor Datasets |
DIELDRIN | review | concentrations in eggs associated with reduced productivity (various raptor species) | Not Reported | Not Reported | Not Reported | NR | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
POLYCHLORINATED BIPHENYLS | review | concentrations in brain associated with mortality (various raptor species) | Not Reported | Not Reported | Not Reported | NR | TOX-MORT - dose-response data | NR | environmental contamination | Toxicity Factor Datasets |
POLYCHLORINATED BIPHENYLS | review | concentrations in eggs associated with reduced reproduction (various raptor species) | Not Reported | Adult | Not Reported | NR | TOX-REPRO - reproductive success | NR | environmental contamination | Toxicity Factor Datasets |
HEPTACHLOR EPOXIDE | review | concentrations in brain associated with mortality (various raptor species) | Not Reported | Not Reported | Not Reported | NR | TOX-MORT - dose-response data | NR | environmental contamination | Toxicity Factor Datasets |