DDE (4,4'-)
Great Horned Owl (Bubo virginianus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, MIREX, OXYCHLORDANE, POLYCHLORINATED BIPHENYLS | increased | mortality due to pesticide exposure based on history, ante-mortem signs, and gross pathology | Not Reported | Not Reported | 8 owls | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), POLYCHLORINATED BIPHENYLS | increased | mortality due to PCB intoxication, based on brain residues | Female | Adult | 1 owl | Greene County | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, OXYCHLORDANE, POLYCHLORINATED BIPHENYLS | increased | occurence of wild birds dying diagnosed with organochlorine poisoning | Both Male and Female | Both Adults and Juveniles | 13 owls | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, OXYCHLORDANE, POLYCHLORINATED BIPHENYLS | increased | occurence of mortality as a result of organochlorine poisoning | Female | Adult | 1 owl | 6 km s. of Corvallis | Toxicity Factor Datasets |
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | mean daily food consumption rate (166.4 g food/kg body weight) | Female | Adult | 5-10/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decreased @ 500, 1000, 5000 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 32% decrease @ 40 mg/kg | Ca2+-Mg2+ ATPase activity in eggshell gland mucosa homogenates, compared to controls | Female | Adult | Not Reported | Toxicity Factor Datasets | 1 yr | Laboratory | |
DDE (4,4'-) | 44% increase @ 40 mg/kg | calcium content (umol/g dry weight) of eggshell gland mucosa, compared to controls | Female | Adult | Not Reported | Toxicity Factor Datasets | 1 yr | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 36-67% decrease @ 10-1000 ppm | salt gland excretion volume, compared to controls | Male | Not Reported | 12/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), LEAD COMPOUNDS, MERCURY COMPOUNDS | decreased @ 40 ppm DDE | eggshell thickness versus controls | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-), LEAD COMPOUNDS, MERCURY COMPOUNDS | decreased with both treatments | eggshell thickness versus controls | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 78.2 (carcass); 61.6 (egg); 4.1 (brain) ppm, wet wt | DDE residues in whole carcass, egg contents, and brain | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, OXYCHLORDANE, POLYCHLORINATED BIPHENYLS | positive correlation | relationships between EROD activity and dieldrin concentrations | Female | Adult | 5 birds/timepoint (timepoints = 0,10,20,32,42,52,59,70,80,90,100 days) | Bloomington | Toxicity Factor Datasets |
DDE (4,4'-), DIELDRIN, OXYCHLORDANE, POLYCHLORINATED BIPHENYLS | positive correlation | relationship between BROD, PROD, and EROD activities and total PCB, oxychlordane, and TEQs concentrations | Female | Adult | 5 birds/timepoint (timepoints = 0,10,20,32,42,52,59,70,80,90,100 days) | Bloomington | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | behavior of offspring; latency in response to approach a maternal call and distance travelled from a frightening stimulus | Female | Adult | 4 adults/dose; 141-175 offspring/dose | Toxicity Factor Datasets | 10 mo | Laboratory | |
DDE (4,4'-) | 0.021 - 0.028 ppm wet wt @ 0 ppm; 5.8 (0.32 SE; range 4.28-7.23) ppm wet wt @ 3 ppm | mean and range of DDE egg concentrations | Female | Adult | 8 eggs/dose | Toxicity Factor Datasets | 10 mo | Laboratory | |
DDE (4,4'-) | increase @ 3 ppm | responsiveness of offspring to maternal call; % that approached call and % that spent 100% of time near call after initial approach | Female | Adult | 4 adults/dose; 148-156 offspring/dose | Toxicity Factor Datasets | 10 mo | Laboratory | |
DDE (4,4'-) | decrease @ 3ppm | decrease in distance traveled in those offspring that traveled more than 10 cm from a frightening stimulus | Female | Adult | 4 adults/dose; 64-71 offspring/dose | Toxicity Factor Datasets | 10 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | onset of laying, egg production, egg fertility and egg hatchability, compared to controls | Female | Adult | 20 hens/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decreased | % normal hatchlings versus controls | Not Reported | Embryo | 492-518, 232-384, and 128-276 for the 0, 10, and 40 ppm DDE groups | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | decreased | number of 14-day old ducklings per hen versus controls | Both Male and Female | Hatchling | 274-327, 69-167, and 26-113 for the 0, 10, and 40 ppm DDE groups | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | increased | % cracked eggs versus controls | Female | Hatchling | 666-696, 620-664, and 317-602 for the 0, 10, and 40 ppm DDE groups | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | decreased | eggshell thickness versus controls | Female | Adult | 20-28, 21-25, and 10-23 for the 0, 10, and 40 ppm DDE groups | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), METHYLMERCURY CHLORIDE | 1.4 +/- 0.18 (@ 1 ppm, no DDE), 8.7 +/- 0.87 (@ 5 ppm, no DDE) ppm Hg, wet wt | mean Hg concentration in third egg laid in clutch (mean +/- SE) | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-), METHYLMERCURY CHLORIDE | 1.0 +/- 0.06 (@ 1 ppm Hg, no DDE), 5.3 +/- 0.56 (@ 5 ppm Hg, no DDE) ppm Hg, wet wt | Hg concentration in breast muscle (mean +/- SE) | Female | Adult | 10/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 20.4% decrease | eggshell thickness versus controls | Female | Adult | 6 hens; 45 total eggs | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 17% decrease | serum calcium versus controls | Female | Adult | 6 hens; 45 total eggs | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | no effect | serum calcium after PTH injection versus controls | Female | Adult | 6 hens; 45 total eggs | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), DDT (4,4'-) | see citation | figure of eggshell thickness over 30 d period (significant differences noted at various times) | Female | Adult | 20/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 10.6 +/- 2.2 ppm nasal gland, 16.1 +/- 5.1 ppm liver, 5.8 +/- 1.1 ppm kidney, 1.9 +/- 0.1 ppm brain @ 100 ppm diet | mean (+/- SE) DDE levels (ppm wet weight) | Both Male and Female | Juvenile | 4 | Toxicity Factor Datasets | 3-5 mo | Laboratory | |
DDE (4,4'-) | no effect | nasal gland secretion volume | Both Male and Female | Juvenile | 5-11 | Toxicity Factor Datasets | 3-5 mo | Laboratory | |
DDE (4,4'-) | no effect | nasal gland and kidney Na-K-ATPase activity, following exposure to 100% seawater | Both Male and Female | Juvenile | 4-5 | Toxicity Factor Datasets | 3-5 mo | Laboratory | |
DDE (4,4'-) | no effect | body weight or plasma electrolyte levels | Both Male and Female | Juvenile | 4 | Toxicity Factor Datasets | 3-5 mo | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | food consumption rate (174 g/d) compared to control (173 g/d) | Female | Adult | 10/dose | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1254, DDE (4,4'-) | no effect | food consumption rate (181 g/d) compared to control (173 g/d) | Female | Adult | 10/dose | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 17% decrease | eggshell thickness, compared to control | Female | Adult | 10 hens /dose; 8 eggs/dose | Toxicity Factor Datasets | Laboratory | |
AROCLOR 1254, DDE (4,4'-) | 19% decrease | eggshell thickness, compared to control | Female | Adult | 10 hens/dose; 8 eggs/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
AROCLOR 1254, DDE (4,4'-) | decreased with all treatments | numbers of mammillary cores and basal caps on eggshell membranes versus controls | Female | Adult | 6-8 eggs/group from 10 hens | Toxicity Factor Datasets | Laboratory |
Peregrine Falcon (Falco peregrinus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, POLYCHLORINATED BIPHENYLS | 15% | percent eggshell thinning compared with pre-DDT reference eggs | Female | Adult | 20 eggs | Rankin Inlet | Toxicity Factor Datasets |
DDE (4,4'-), DIELDRIN, POLYCHLORINATED BIPHENYLS | 0.12 (0-2.59; PCBs); 0.06 (0-2.70; DDE); ND (0-0.06; dieldrin) | geometric mean residues (range) in plasma, ppm, wet wt of nestlings | Not Reported | Juvenile | 79 nestlings | Rankin Inlet | Toxicity Factor Datasets |
DDE (4,4'-), DIELDRIN, POLYCHLORINATED BIPHENYLS | males: 0.15 (0-3.27; PCBs); 0.31 (0.05-1.95; DDE); 0.03 (0-0.30; dieldrin) females: 0.87 (0-6.82; PCBs); 0.63 (0-4.23; DDE); 0.04 (0-0.37; dieldrin) |
geometric mean residues (range) in plasma, ppm, wet wt of adult birds | Both Male and Female | Adult | 26 males, 34 females | Rankin Inlet | Toxicity Factor Datasets |
DDE (4,4'-), DIELDRIN, POLYCHLORINATED BIPHENYLS | liver: 1.58-59.45, PCBs; 0.99-18.84, DDE; 0.06-0.79, dieldrin breast: 0.35-57.30, PCBs; 0.30-16.95, DDE; 0-0.19, dieldrin |
range of residues in liver and breast muscle (ppm, wet wt) of 22-31 day old nestlings found dead | Not Reported | Juvenile | 7 birds | Rankin Inlet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 21:0.09 | ratio of average concentration of DDE in eggs to average concentration of DDE in prey items | Female | Adult | 12 prey species, pooled samples of 7-10 individuals | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Condition | Countries |
---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | eggshell thickness index = 1.799 - 0.243(log DDE) | linear regression of eggshell thickness index vs. log DDE concentration in eggs | Female | Adult | 295 eggs | Toxicity Factor Datasets | eggs were addled and/or deserted | UNITED KINGDOM | |
DDE (4,4'-) | productivity = 1.412 - 0.724(log DDE) | linear regression of productivity (mean number of young raised per pair) vs. log DDE concentration in eggs | Both Male and Female | Adult | 14 pairs | Toxicity Factor Datasets | UNITED KINGDOM | ||
DDE (4,4'-), HEPTACHLOR EPOXIDE | 15 ppm DDE, 0.7 ppm heptachlor epoxide | concentrations in eggs associated with population recovery | Both Male and Female | Both Adults and Juveniles | 550 eggs from 469 clutches | Toxicity Factor Datasets | UNITED KINGDOM |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | review | concentrations of chemicals in eggs and diet associated with mortality and eggshell thinning (various raptor species) | Not Reported | Adult | Not Reported | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), POLYCHLORINATED BIPHENYLS | 11.4% | percent eggshell thinning compared to pre-DDT reference eggs | Female | Adult | 8 nests | Kola Peninsula | Toxicity Factor Datasets | RUSSIA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 12.7 +/- 8.7 ppm (wet wt), 253 +/- 160 ppm (lipid wt) | mean (+/-SE) DDE concentration in eggs | Female | Adult | 10 eggs | Ungava region, Quebec; islands of Northwest Territories | Toxicity Factor Datasets | CANADA |
DDE (4,4'-) | 21% decrease | eggshell thickness compared to pre-1940 museum specimens | Female | Adult | 21 eggs from 12 clutches | Ungava region, Quebec; islands of Northwest Territories | Toxicity Factor Datasets | CANADA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE | no effect | number of viable eggs or young versus "normal" nest success | Not Reported | Juvenile | 15 nests | Peace, Slave, and Mackenzie Rivers | Toxicity Factor Datasets | CANADA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 16% | percent eggshell thinning compared to pre-1947 reference eggs | Female | Adult | 13 eggs | South Australia | Toxicity Factor Datasets | AUSTRALIA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, POLYCHLORINATED BIPHENYLS | 15.8% | mean eggshell thinning compared to "pre-pesticide" reference eggs | Female | Adult | 78 eggs | Rankin Inlet | Toxicity Factor Datasets |
DDE (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, POLYCHLORINATED BIPHENYLS | log DDE in eggs = 0.9723 + 0.8506(log DDE in plasma); r = 0.66 | log-log relationship between DDE in plasma of female birds and DDE in eggs | Female | Adult | 10 females | Rankin Inlet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | eggshell thickness index = 1.888 - 0.281(log DDE) | linear regression of eggshell thickness index and DDE content of eggs | Female | Adult | 137 eggs | Tasmania, Victoria, South Australia | Toxicity Factor Datasets | AUSTRALIA |
DDE (4,4'-) | productivity = 1.79 - 0.04(DDE) | linear regression of productivity (number of young fledged per site) and DDE concentrations in eggs | Both Male and Female | Adult | 9 eggs | Tasmania | Toxicity Factor Datasets | AUSTRALIA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), HEPTACHLOR EPOXIDE, OXYCHLORDANE, POLYCHLORINATED BIPHENYLS | 12.1% | percent eggshell thinning (as indicated by Ratcliffe Index) compared to pre-1947 eggs | Not Reported | Embryo | 39 eggs | Mid-Atlantic coastal and urban breeding sites | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), POLYCHLORINATED BIPHENYLS | 11% decrease | eggshell thickness compared to pre-1947 reference eggs | Female | Adult | 112 eggs | eastern U.S. coast | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 1.89 (1.27-2.43) -6.96 (3.28-13.37) ppm, wet wt | annual mean (range) concentrations in eggs | Female | Adult | 3-6 eggs/year | Amchitka Island | Toxicity Factor Datasets |
DDE (4,4'-) | 7.5% decrease | eggshell thickness compared to "pre-pesticide" reference eggs | Female | Adult | 3-6 eggs/year | Amchitka Island | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | review | data correlating eggshell thinning and DDE concentrations in eggs | Female | Adult | Not Reported | Toxicity Factor Datasets | GLOBAL |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
AROCLOR 1248, AROCLOR 1254, AROCLOR 1260, DDE (4,4'-), DDT (4,4'-), MERCURY COMPOUNDS | no effect | eggshell thickness compared to pre-1947 reference eggs | Female | Adult | 9 eggs | urban nest sites | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no relation | linear regression of eggshell thickness and DDE concentration in eggs | Female | Adult | 35 eggs | Victoria | Toxicity Factor Datasets | AUSTRALIA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 13.1% and 13.6% decreases in tundrius and anatum ssp. | eggshell thickness compared to pre-1947 reference eggs | Female | Adult | 21 and 34 eggs for tundrius and anatum ssp. | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 21.7% decrease (tundra population); 16.8% decrease (taiga population); 7.5% decrease (Aleutian population) | eggshell thickness compared to pre-1947 reference eggs | Female | Adult | 23 eggs (tundra pop.); 14 eggs (taiga pop.); 11 eggs (Aleutian pop.) | Colville River (tundra); Yukon River (taiga); Amchitka Island (Aleutian) | Toxicity Factor Datasets |
Burrowing Owl (Athene cunicularia formerly Speotyto cunicularia), Great Horned Owl (Bubo virginianus)
Chemical | Endpoint Value | Location | Type |
---|---|---|---|
CARBARYL, CARBOFURAN, DDE (4,4'-) | review | Toxicity Factor Datasets |
American Kestrel (Falco sparverius)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | calcium concentration in blood | Female | Adult | 8/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 232.9 ppm (dry wt) | mean brain residues in birds that survived | Male | Adult | 11 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 507-877.1 ppm (dry wt) | liver residues in birds that died | Male | Adult | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-) | 88.1 ppm (dry wt) | mean liver residues in birds that survived | Male | Adult | 11 | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decrease at all doses (15.1-29.2%) | eggshell thickness | Female | Adult | 2-5 pairs/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 5.53 mg/kg egg (wet wt) | mean DDE concentration in eggs (pooled analyses) | Both Male and Female | Embryo | 10 eggs | N. Niagra Peninsula, Ontario | Toxicity Factor Datasets | CANADA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, OXYCHLORDANE, POLYCHLORINATED BIPHENYLS | increased | occurence of wild birds dying diagnosed with organochlorine poisoning | Both Male and Female | Both Adults and Juveniles | 5 kestrels | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
ACEPHATE, DDE (4,4'-) | no effect | prey capturing behavior | Not Reported | Adult | 5-6/group | Toxicity Factor Datasets | Laboratory | |
ACEPHATE, DDE (4,4'-) | decrease for both treatments | median serum cholinesterase activity 24 hr post-dose | Not Reported | Adult | 5-6/group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 10% decrease | eggshell thickness change relative to control | Female | Adult | 34 eggs | Cayuga Lake Basin | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | 1.05 (0.05 SE) ppm (wet wt) | lead concentration in liver | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | 0.70 (0.20 SE) ppm (wet wt) | lead concentration in tibia | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | 232 (9 SE) ppm (wet wt) | DDE concentration in carcass | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | 10.4 (0.6 SE) ppm (wet wt) | DDE concentration in brain | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | decreased | bw (versus pre-study bw) | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory |
California Brown Pelican (Pelecanus occidentalis ssp. californicus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | increased compared to positive control (1969 data) | mean number of fledglings produced per nest in 1974 | Both Male and Female | Fledgling | 1286 nests | Anacapa Island and Isla Coronado Norte | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | non-detectable DDT plus TDE, 96.6 ppm DDE, lipid wet basis | concentration in egg contents | Female | Adult | 39 eggs | Anacapa Island and Isla Coronado Norte | Toxicity Factor Datasets |
Brown Pelican (Pelecanus occidentalis)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
AROCLOR 1254, DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN | 0.896 ppm DDE, 0.256 ppm DDD, 0.166 ppm DDT, 0.208 dieldrin, 2.241 ppm PCB 1254 | mean residues in eggs | Female | Adult | 29 eggs | east coast | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 8 ug/g | critical threshold of DDE concentration in egg (wet wt basis) associated with 20% eggshell thinning | Both Male and Female | Embryo | 813 eggs | Toxicity Factor Datasets | |
DDE (4,4'-) | 3 ug/g | lowest level of DDE that would result in severely lowered reproductive success | Both Male and Female | Embryo | 156 eggs | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 3 ug/g | level in eggs associated with impaired reproductive success (successful nests fledged at least one chick) | Both Male and Female | Juvenile | 156 eggs | Toxicity Factor Datasets |
Loggerhead Shrike (Lanius ludovicianus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | California Counties |
---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | 293.43-820.93 ppm, lipid weight | concentrations of DDT, DDE, DDD (combined) in skin and brains, 2 years post-application | Not Reported | Not Reported | 2 birds | 3.2 km NE of Davis | Toxicity Factor Datasets | Yolo |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | see figure | figure showing concentration of DDT and metabolites in skin and brains before and after application | Not Reported | Not Reported | 27 birds (3-4/sampling time) | 3.2 km NE of Davis | Toxicity Factor Datasets | Yolo |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 3.09 (0.09 SE) ppm, wet wt | concentration in eggs | Not Reported | Embryo | 20 clutches, 104 eggs | southern IL | Toxicity Factor Datasets |
DDE (4,4'-) | decreased | eggshell thickness index compared with reference samples collected in 1875-95 | Not Reported | Embryo | 20 clutches, 104 eggs | southern IL | Toxicity Factor Datasets |
DDE (4,4'-) | y = 92.610 - 2.412 log x | linear negative correlation of egg DDE concentration and shell thickness | Not Reported | Embryo | 20 clutches, 104 eggs | southern IL | Toxicity Factor Datasets |
Western Grebe (Aechmophorus occidentalis)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-) | decreased compared with pre-1940 eggs | eggshell thickness index (Ratcliffe's Index) | Not Reported | Embryo | 93 eggs | Bear River Migratory Bird Refuge | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-) | 12.8 ppm DDE, 0.8 ppm DDD, wet wt | mean concentration in breast muscle | Not Reported | Adult | 24 birds | Bear River Migratory Bird Refuge | Toxicity Factor Datasets |
DDE (4,4'-) | 61.5 ppm DDE, 5.2 ppm DDD, wet wt | mean concentration in visceral fat | Not Reported | Adult | 18 birds | Bear River Migratory Bird Refuge | Toxicity Factor Datasets |
DDE (4,4'-) | 0.55 ppm DDE, 0.07 ppm DDD, wet wt | mean concentration in blood | Not Reported | Adult | 16 birds | Bear River Migratory Bird Refuge | Toxicity Factor Datasets |
Pallid Bat (Antrozous pallidus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 5.8 ppm; range, 3.6-8.2 ppm (wet wt) | mean and range of concentration in carcass, wet wt | Both Male and Female | Adult | 4 bats | near cities | Toxicity Factor Datasets | MEXICO |
Double-crested Cormorant (Phalacrocorax auritus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), POLYCHLORINATED BIPHENYLS | 10.4 ppm DDE, 8 ppm est. PCBs, <0.1 ppm DDD, 0.2 ppm DDT | residues measured in live and dead eggs | Female | Adult | 11 colonies | Toxicity Factor Datasets | CANADA | |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), POLYCHLORINATED BIPHENYLS | negative correlation | correlation of egg concentration of DDE and est. PCB's and shell thickness and weight | Female | Adult | 35 eggs | Toxicity Factor Datasets | CANADA |
Least Tern (Sterna antillarum)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), POLYCHLORINATED BIPHENYLS | 7% decrease | eggshell thickness compared with pre-1947 reference eggs | Female | Adult | 20 eggs | Cape Romain National Wildlife Refuge | Toxicity Factor Datasets |