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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
LEAD ACETATE | See citation Table 1 | Hematological chemistry | M | Both Adults and Juveniles | US Army Center for Health Promotion and Preventive Medicine | 42 | 0, 1, 10, 20 mg/kg/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 14 d | Oral gavage | Toxicity Factor Datasets |
2,4-DINITROTOLUENE | 380 mg/kg [149-515 (95% CI)] | LD50 | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 4-20 | 0-1000mg/kg; see citation for stages | TOX-MORT - toxicity benchmarks | 14 d | Toxicity Factor Datasets | |
2,4-DINITROTOLUENE | 577 mg/kg [406-785 (95% CI)] | LD50 | F | Adult | US Army Center for Health Promotion and Preventive Medicine | 4-20 | 0-1000mg/kg; see citation for stages | TOX-MORT - toxicity benchmarks | 14 d | Toxicity Factor Datasets | |
2,4-DINITROTOLUENE | 50 mg/kg | NOEC | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 42 | 0, 6.25, 12.5, 25, 50, 100, 200 mg/kg/d | 14 d | Toxicity Factor Datasets | ||
2,4-DINITROTOLUENE | Time dependent; see citation | Body weight change | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 60 | 0, 9, 15, 25, 42, 70 mg/kg/d | TOX-MORT - toxicity benchmarks | 60 d | Toxicity Factor Datasets | |
2,4-DINITROTOLUENE | No effect | Liver weight | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 60 | 0, 9, 15, 25, 42, 70 mg/kg/d | TOX-Non-Repro-Sublethal - organ/system effects | 60 d | Toxicity Factor Datasets | |
2,4-DINITROTOLUENE | Increased | Kidney weight | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 60 | 0, 9, 15, 25, 42, 70 mg/kg/d | TOX-Non-Repro-Sublethal - organ/system effects | 60 d | Toxicity Factor Datasets | |
2,4-DINITROTOLUENE | No effect | Body fat | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 60 | 0, 9, 15, 25, 42, 70 mg/kg/d | TOX-Non-Repro-Sublethal - organ/system effects | 60 d | Toxicity Factor Datasets | |
2,4-DINITROTOLUENE | No effect | Testes weight | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 60 | 0, 9, 15, 25, 42, 70 mg/kg/d | TOX-Non-Repro-Sublethal - organ/system effects | 60 d | Toxicity Factor Datasets | |
2,4-DINITROTOLUENE | No effect | Brain weight | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 60 | 0, 9, 15, 25, 42, 70 mg/kg/d | TOX-Non-Repro-Sublethal - organ/system effects | 60 d | Toxicity Factor Datasets | |
2,4-DINITROTOLUENE | No effect | Hematological chemistry | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 60 | 0, 9, 15, 25, 42, 70 mg/kg/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 60 d | Toxicity Factor Datasets | |
2,4-DINITROTOLUENE | Increased | Blood uric acid | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 60 | 0, 9, 15, 25, 42, 70 mg/kg/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 60 d | Toxicity Factor Datasets | |
2,4-DINITROTOLUENE | Increased | Blood phosphorus | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 60 | 0, 9, 15, 25, 42, 70 mg/kg/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 60 d | Toxicity Factor Datasets | |
2,4-DINITROTOLUENE | See citation | Testosterone concentation | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 60 | 0, 9, 15, 25, 42, 70 mg/kg/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 60 d | Toxicity Factor Datasets | |
2,4-DINITROTOLUENE | Increased | Hanging, arched posture, dark coloration | M | Adult | US Army Center for Health Promotion and Preventive Medicine | 60 | 0, 9, 15, 25, 42, 70 mg/kg/d | TOX-Non-Repro-Sublethal - behavioral effects | 60 d | Toxicity Factor Datasets | |
HYDROGEN SULFIDE | No effect | Righting reflex, sprinting, prey capture | NR | Not Reported | Texas Tech University | 66 | 0, 30, 90, 140, 150, 160 ppm | TOX-Non-Repro-Sublethal - behavioral effects | 90 m | Airborne | Toxicity Factor Datasets |
BROMACIL | No effect | Righting reflex, sprinting, prey capture | NR | Not Reported | Texas Tech University | 30 | 0, 1x, 2x label rate | TOX-Non-Repro-Sublethal - behavioral effects | Single dose | Dorsal application | Toxicity Factor Datasets |
DIURON | No effect | Righting reflex, sprinting, prey capture | NR | Not Reported | Texas Tech University | 30 | 0, 1x, 2x label rate | TOX-Non-Repro-Sublethal - behavioral effects | Single dose | Dorsal application | Toxicity Factor Datasets |
AMMONIUM CHLORIDE | No effect | Righting reflex, sprinting, prey capture | NR | Not Reported | Texas Tech University | 30 | 0, 1x, 2x label rate | TOX-Non-Repro-Sublethal - behavioral effects | Single dose | Dorsal application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY | See citation Table 2 | Immune responses | M | Adult | Patuxent Wildlife Research Center, Laurel | 59 | 0, 0.6, 3.9 µg/g food dry weight | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 13 w | Dietary | Toxicity Factor Datasets |
METHYLMERCURY | See citation Table 3 | Hematological chemistry | M | Adult | Patuxent Wildlife Research Center, Laurel | 59 | 0, 0.6, 3.9 µg/g food dry weight | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 13 w | Dietary | Toxicity Factor Datasets |
METHYLMERCURY | See citation Table 1 | Cum survivorship | B | Nestling | Patuxent Wildlife Research Center, Laurel | 154 | 0, 0.6, 3.9 µg/g food dry weight | TOX-MORT - toxicity benchmarks | 25 d | Dietary via parent regurgitation & self-feeding | Toxicity Factor Datasets |
METHYLMERCURY | Increased | Blood total Hg | B | Nestling | Patuxent Wildlife Research Center, Laurel | 154 | 0, 0.6, 3.9 µg/g food dry weight | TOX-EXP IND - accumulation | 25 d | Dietary via parent regurgitation & self-feeding | Toxicity Factor Datasets |
METHYLMERCURY | Increased | Spleen total Hg | B | Nestling | Patuxent Wildlife Research Center, Laurel | 154 | 0, 0.6, 3.9 µg/g food dry weight | TOX-EXP IND - accumulation | 25 d | Dietary via parent regurgitation & self-feeding | Toxicity Factor Datasets |
METHYLMERCURY | Increased | Thymus total HG | B | Nestling | Patuxent Wildlife Research Center, Laurel | 154 | 0, 0.6, 3.9 µg/g food dry weight | TOX-EXP IND - accumulation | 25 d | Dietary via parent regurgitation & self-feeding | Toxicity Factor Datasets |
METHYLMERCURY | No effect | Body mass | B | Nestling | Patuxent Wildlife Research Center, Laurel | 154 | 0, 0.6, 3.9 µg/g food dry weight | TOX-Non-Repro-Sublethal - whole animal | 25 d | Dietary via parent regurgitation & self-feeding | Toxicity Factor Datasets |
METHYLMERCURY | See citation Table 4 | Immune responses | B | Nestling | Patuxent Wildlife Research Center, Laurel | 154 | 0, 0.6, 3.9 µg/g food dry weight | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 25 d | Dietary via parent regurgitation & self-feeding | Toxicity Factor Datasets |
METHYLMERCURY | No effect | Spleen weight | B | Nestling | Patuxent Wildlife Research Center, Laurel | 154 | 0, 0.6, 3.9 µg/g food dry weight | TOX-Non-Repro-Sublethal - whole animal | 25 d | Dietary via parent regurgitation & self-feeding | Toxicity Factor Datasets |
METHYLMERCURY | See citation Table 5 | Immune responses | B | Nestling | Patuxent Wildlife Research Center, Laurel | 154 | 0, 0.6, 3.9 µg/g food dry weight | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 25 d | Dietary via parent regurgitation & self-feeding | Toxicity Factor Datasets |
PCB | 0.25 | Aggressive courtship | B | Adult | University of Saskatchewan | F0: 50 pairs | 5-7 µg total PCBs/g body weight/day | TOX-REPRO - behavior | 1 m prior to pairing-egg hatching | Dietary | Toxicity Factor Datasets |
PCB | 0.08 | Abandoned incubation | B | Adult | University of Saskatchewan | F0: 50 pairs | 5-7 µg total PCBs/g body weight/day | TOX-REPRO - behavior | 1 m prior to pairing-egg hatching | Dietary | Toxicity Factor Datasets |
PCB | 0.6 | Cracked eggs, multiple | B | Adult | University of Saskatchewan | F0: 50 pairs | 5-7 µg total PCBs/g body weight/day | TOX-REPRO - development | 1 m prior to pairing-egg hatching | Dietary | Toxicity Factor Datasets |
PCB | 0.64 | Embryo abnormalities | B | Adult | University of Saskatchewan | F0: 50 pairs | 5-7 µg total PCBs/g body weight/day | TOX-REPRO - development | 1 m prior to pairing-egg hatching | Dietary | Toxicity Factor Datasets |
PCB | 0.29 | Hatchling abnormalities | B | Adult | University of Saskatchewan | F0: 50 pairs | 5-7 µg total PCBs/g body weight/day | TOX-REPRO - development | 1 m prior to pairing-egg hatching | Dietary | Toxicity Factor Datasets |
PCB | No effect | Aggressive courtship | B | Adult | University of Saskatchewan | F0: 50 pairs | Previous year: 5-7 µg total PCBs/g body weight/day | TOX-REPRO - behavior | Exposed previous year for 1 m prior to pairing-egg hatching | Dietary | Toxicity Factor Datasets |
PCB | No effect | Abandoned incubation | B | Adult | University of Saskatchewan | F0: 50 pairs | Previous year: 5-7 µg total PCBs/g body weight/day | TOX-REPRO - behavior | Exposed previous year for 1 m prior to pairing-egg hatching | Dietary | Toxicity Factor Datasets |
PCB | No effect | Cracked eggs, multiple | B | Adult | University of Saskatchewan | F0: 50 pairs | Previous year: 5-7 µg total PCBs/g body weight/day | TOX-REPRO - development | Exposed previous year for 1 m prior to pairing-egg hatching | Dietary | Toxicity Factor Datasets |
PCB | 0.78 | Embryo abnormalities | B | Adult | University of Saskatchewan | F0: 50 pairs | Previous year: 5-7 µg total PCBs/g body weight/day | TOX-REPRO - development | Exposed previous year for 1 m prior to pairing-egg hatching | Dietary | Toxicity Factor Datasets |
PCB | 0.11 | Hatchling abnormalities | B | Adult | University of Saskatchewan | F0: 50 pairs | Previous year: 5-7 µg total PCBs/g body weight/day | TOX-REPRO - development | Exposed previous year for 1 m prior to pairing-egg hatching | Dietary | Toxicity Factor Datasets |
PCB | 34.1 µg/g | Egg concentrations | NR | Embryo | University of Saskatchewan | NR | in ovo, 5-7 µg/kg body weight /day parent diet | TOX-EXP IND - accumulation | Parents exposed for 1 m prior to pairing-egg hatching | In ovo | Toxicity Factor Datasets |