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Anaxyrus boreas (Western Toad)

Citation:
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Location Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
LEAD ACETATE See citation Figure 2 Mean max sprint velocity, m/s NR Juvenile Savannah River Ecology Laboratory 10 0, 1.0, 10, 100, 1000 mg/kg TOX-Non-Repro-Sublethal - behavioral effects Single dose Oral gavage Toxicity Factor Datasets
MALATHION No effect Food consumption M Juvenile Savannah River Ecology Laboratory 13 2.0, 20, 100 mg/kg TOX-Non-Repro-Sublethal - behavioral effects Dosed 3 times over 81 days Oral gavage Toxicity Factor Datasets
MALATHION No effect Mass, g M Juvenile Savannah River Ecology Laboratory 13 2.0, 20, 100 mg/kg TOX-Non-Repro-Sublethal - whole animal Dosed 3 times over 81 days Oral gavage Toxicity Factor Datasets

Dipsosaurus dorsalis (Desert Iguana)

Citation:
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
2,4,6-TRINITROTOLUENE 1038 mg/kg [332-2360 (95% CI)] LD50 F Adult 30 0, 200-5000 mg/kg TOX-MORT - toxicity benchmarks Single dose Oral gavage Toxicity Factor Datasets
2,4,6-TRINITROTOLUENE 1579 mg/kg [593-3356 (95% CI)] LD50 M Adult 30 0, 200-6300 mg/kg TOX-MORT - toxicity benchmarks Single dose Oral gavage Toxicity Factor Datasets
2,4,6-TRINITROTOLUENE Threshold dose 66-132 mg/kg/d; decrease Days of survival B Adult 42 0, 33, 66, 132, 263, 525, 1050 mg/kg/d TOX-MORT - dose-response data Daily doses through mortality Oral gavage Toxicity Factor Datasets
2,4,6-TRINITROTOLUENE No effect Hematological chemistry M Adult 42 0, 33, 66, 132, 263, 525, 1050 mg/kg/d TOX-Non-Repro-Sublethal - cellular/biochemical effects Daily doses through mortality Oral gavage Toxicity Factor Datasets

Gopherus agassizi (Desert Tortoise)

Citation:
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Location Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE No effect Spleen/brain weight M Adult U.S. Army Center for Health Promotion and Preventive Medicine 60 0, 1, 2.5, 5, 8, 11 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 60 d Oral gavage Toxicity Factor Datasets
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE Decreased Testes/brain weight M Adult U.S. Army Center for Health Promotion and Preventive Medicine 60 0, 1, 2.5, 5, 8, 11 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 60 d Oral gavage Toxicity Factor Datasets
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE See citation Histopathology M Adult U.S. Army Center for Health Promotion and Preventive Medicine 60 0, 1, 2.5, 5, 8, 11 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 60 d Oral gavage Toxicity Factor Datasets
HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE No effect Hematological chemistry M Adult U.S. Army Center for Health Promotion and Preventive Medicine 60 0, 1, 2.5, 5, 8, 11 mg/kg/d TOX-Non-Repro-Sublethal - cellular/biochemical effects 60 d Oral gavage Toxicity Factor Datasets

Pituophis melanoleucus (Pine Snake)

Citation:
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Location Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
2-AMINO-4,6-DINITROTOLUENE No effect Hematological chemistry M Adult 42 0, 15, 24, 38, 60, 95, 150 mg/kg/d TOX-Non-Repro-Sublethal - cellular/biochemical effects 14 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE Present Chromaturia/vent area staining M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 60 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE Decreased Days of survival M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-MORT - toxicity benchmarks 60 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE Decreased Cricket consumption M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-Non-Repro-Sublethal - whole animal 60 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE Decreased >5 mg/kg/d Body weight change M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-Non-Repro-Sublethal - whole animal 60 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE Threshold dose 5-15 mg/kg/d Chromaturia/vent area staining M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 60 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE No effect Liver weight M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 60 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE Increased Kidney weight M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 60 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE Increased Spleen weight M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 60 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE Decreased Testes weight M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 60 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE See citation Histopathology M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 60 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE No effect Hematological chemistry M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-Non-Repro-Sublethal - cellular/biochemical effects 60 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE Increased Blood Hct M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-Non-Repro-Sublethal - cellular/biochemical effects 60 d Oral gavage Toxicity Factor Datasets
2-AMINO-4,6-DINITROTOLUENE No effect Spermatozoa counts/motility M Adult 42 0, 5, 15, 20, 25, 30 mg/kg/d TOX-Non-Repro-Sublethal - cellular/biochemical effects 60 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE 2000 mg/kg Approximate LD50 M Adult US Army Center for Health Promotion and Preventive Medicine 9 0, 100, 200, 500, 1000, 2000, 3000, 4000, 8000 mg/kg TOX-MORT - toxicity benchmarks Single dose Oral gavage Toxicity Factor Datasets
LEAD ACETATE 2000 mg/kg Approximate LD50 F Adult US Army Center for Health Promotion and Preventive Medicine 9 0, 100, 200, 500, 1000, 2000, 3000, 4000, 8000 mg/kg TOX-MORT - toxicity benchmarks Single dose Oral gavage Toxicity Factor Datasets
LEAD ACETATE 13 d Days of survival M Adult US Army Center for Health Promotion and Preventive Medicine 42 0, 31.25, 62.50, 125, 250, 500, 1000 mg/kg/d TOX-MORT - toxicity benchmarks 14 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE 11 d Days of survival F Adult US Army Center for Health Promotion and Preventive Medicine 42 0, 31.25, 62.50, 125, 250, 500, 1000 mg/kg/d TOX-MORT - toxicity benchmarks 14 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE See citation Body weight change B Adult US Army Center for Health Promotion and Preventive Medicine 42 0, 31.25, 62.50, 125, 250, 500, 1000 mg/kg/d TOX-Non-Repro-Sublethal - whole animal 14 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE Decreased Cricket consumption B Adult US Army Center for Health Promotion and Preventive Medicine 42 0, 31.25, 62.50, 125, 250, 500, 1000 mg/kg/d TOX-Non-Repro-Sublethal - whole animal 14 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE No effect Mortality M Both Adults and Juveniles US Army Center for Health Promotion and Preventive Medicine 42 0, 1, 10, 20 mg/kg/d TOX-MORT - toxicity benchmarks 14 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE See citation Body weight change M Both Adults and Juveniles US Army Center for Health Promotion and Preventive Medicine 42 0, 1, 10, 20 mg/kg/d TOX-Non-Repro-Sublethal - whole animal 14 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE Decreased Cricket consumption M Juvenile US Army Center for Health Promotion and Preventive Medicine 42 0, 1, 10, 20 mg/kg/d TOX-Non-Repro-Sublethal - whole animal 14 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE No effect Liver weight M Both Adults and Juveniles US Army Center for Health Promotion and Preventive Medicine 42 0, 1, 10, 20 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 14 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE Increased Kidney weight M Both Adults and Juveniles US Army Center for Health Promotion and Preventive Medicine 42 0, 1, 10, 20 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 14 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE Decreased Body fat M Both Adults and Juveniles US Army Center for Health Promotion and Preventive Medicine 42 0, 1, 10, 20 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 14 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE Decreased Testes weight M Both Adults and Juveniles US Army Center for Health Promotion and Preventive Medicine 42 0, 1, 10, 20 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 14 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE No effect Brain weight M Both Adults and Juveniles US Army Center for Health Promotion and Preventive Medicine 42 0, 1, 10, 20 mg/kg/d TOX-Non-Repro-Sublethal - organ/system effects 14 d Oral gavage Toxicity Factor Datasets
LEAD ACETATE Increased Gaping, arched posture, dark coloration M Both Adults and Juveniles US Army Center for Health Promotion and Preventive Medicine 42 0, 1, 10, 20 mg/kg/d TOX-Non-Repro-Sublethal - behavioral effects 14 d Oral gavage Toxicity Factor Datasets
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