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Lithobates catesbeianus

Citation:

Teratogenesis, toxicity and bioaccumulation in frogs exposed to dieldrin

Author(s)
Schuytema, Gerald S., Alan V. Nebeker, William L. Griffis and Karsten N. Wilson
Pages
332-350
Year
Volume
21
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
DIELDRIN 25.1 ug/l LOAEL, based on mortality but gross spinal deformities also observed Not Reported Embryo 20 animals/replicate; 4 replicates/dose 0, 0.8, 2.0, 4.9, 11.0, 25.4, 64.8, 154.8 ug/l TOX-MORT - toxicity benchmarks 21 d waterborne Toxicity Factor Datasets
DIELDRIN 11.0 ug/l NOAEL Not Reported Embryo 20 animals/replicate; 4 replicates/dose 0, 0.8, 2.0, 4.9, 11.0, 25.4, 64.8, 154.8 ug/l TOX-MORT - toxicity benchmarks 21 d waterborne Toxicity Factor Datasets
DIELDRIN 8.7 ug/l (95% CL: 7.8-9.7 ug/l) LC50 Not Reported Tadpole 20 animals/replicate; 4 replicates/dose 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l TOX-MORT - toxicity benchmarks 4 d waterborne Toxicity Factor Datasets
DIELDRIN 11.2 ug/l LOAEL Not Reported Tadpole 20 animals/replicate; 4 replicates/dose 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l TOX-MORT - toxicity benchmarks 4 d waterborne Toxicity Factor Datasets
DIELDRIN 4.0 ug/l NOAEL Not Reported Tadpole 20 animals/replicate; 4 replicates/dose 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l TOX-MORT - toxicity benchmarks 4 d waterborne Toxicity Factor Datasets
DIELDRIN 5.1 ug/g at 8.7 ug/l whole body dieldrin concentration (ug/g, wet wt.) at the LC50 Not Reported Tadpole Not Reported 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l TOX-EXP IND - accumulation 4 d waterborne Toxicity Factor Datasets
DIELDRIN 6.0 ug/g at 11.2 ug/l whole body dieldrin concentration (ug/g, wet wt.) Not Reported Tadpole Not Reported 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l TOX-EXP IND - accumulation 4 d waterborne Toxicity Factor Datasets
DIELDRIN 2.0 ug/g at 4.0 ug/l whole body dieldrin concentration (ug/g, wet wt.) Not Reported Tadpole Not Reported 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l TOX-EXP IND - accumulation 4 d waterborne Toxicity Factor Datasets
DIELDRIN 360 - 540 range of bioconcentration factors; calculated by dividing the whole body tissue dieldrin concentration by water dieldrin concentration Not Reported Tadpole 20 animals/replicate; 4 replicates/dose 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l TOX-EXP IND - accumulation 4 d waterborne Toxicity Factor Datasets
DIELDRIN 36,000 - 54,000 range of lipid bioconcentration factors; calculated by dividing the whole body bioconcentration values x 100 by percent lipid Not Reported Tadpole 20 animals/replicate; 4 replicates/dose 0, 2.2, 4.0, 11.2, 46.5, 179.9 ug/l TOX-EXP IND - accumulation 4 d waterborne Toxicity Factor Datasets
DIELDRIN 30.3 ug/l (95% CL: 26.2 - 35.2 ug/l) LC50 Not Reported Tadpole 20 animals/replicate; 4 replicates/dose 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l TOX-MORT - toxicity benchmarks 4 d waterborne Toxicity Factor Datasets
DIELDRIN 52.3 ug/l LOAEL Not Reported Tadpole 20 animals/replicate; 4 replicates/dose 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l TOX-MORT - toxicity benchmarks 4 d waterborne Toxicity Factor Datasets
DIELDRIN 12.3 ug/l NOAEL Not Reported Tadpole 20 animals/replicate; 4 replicates/dose 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l TOX-MORT - toxicity benchmarks 4 d waterborne Toxicity Factor Datasets
DIELDRIN 12.0 ug/g at 30.3 ug/l whole body dieldrin concentration (ug/g, wet wt.) at the LC50 Not Reported Tadpole Not Reported 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l TOX-EXP IND - accumulation 4 d waterborne Toxicity Factor Datasets
DIELDRIN 19.0 ug/g at 52.3 ug/l whole body dieldrin concentration (ug/g, wet wt.) Not Reported Tadpole Not Reported 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l TOX-EXP IND - accumulation 4 d waterborne Toxicity Factor Datasets
DIELDRIN 0.5 ug/g at 12.3 ug/l whole body dieldrin concentration (ug/g, wet wt.) at the NOAEL Not Reported Tadpole Not Reported 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l TOX-EXP IND - accumulation 4 d waterborne Toxicity Factor Datasets
DIELDRIN 360 - 900 range of bioconcentration factors; calculated by dividing the whole body tissue dieldrin concentration by water dieldrin concentration Not Reported Tadpole 20 animals/replicate; 4 replicates/dose 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l TOX-EXP IND - accumulation 4 d waterborne Toxicity Factor Datasets
DIELDRIN 36,000 - 90,000 range of lipid bioconcentration factors; calculated by dividing the whole body bioconcentration values x 100 by percent lipid Not Reported Tadpole 20 animals/replicate; 4 replicates/dose 0, 1.0, 3.8, 12.3, 52.3, 182.0 ug/l TOX-EXP IND - accumulation 4 d waterborne Toxicity Factor Datasets
Citation:

Behavior of tadpoles of the bullfrog, Rana catesbeiana, in response to sublethal lead exposure

Author(s)
Steele, Craig W., Shari Strickler-Shaw and Douglas H. Taylor
Pages
331-344
Year
Volume
14
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
LEAD NITRATE no effect preference/avoidance behavior and spontaneous locomotor activity Not Reported Tadpole 8 animals/dose 0, 500, 625, 750, 1000 ug/l TOX-REPRO - behavior 6 d waterborne Toxicity Factor Datasets
Citation:

Toxicity of Zectran insecticide to several wildlife species

Author(s)
Tucker, Richard K. and D. Glen Crabtree
Pages
1307-1310
Year
Issue
6
Volume
62
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
MEXACARBATE 283 - 800 mg/kg LD50, estimated Male Not Reported 14 NR TOX-MORT - toxicity benchmarks single gavage Toxicity Factor Datasets

Falco sparverius

Citation:

Enzymatic changes in the oviduct associated with DDE-induced eggshell thinning in the kestrel, Falco sparverius

Author(s)
Bird, David M., David B. Peakall and David S. Miller
Pages
22-24
Year
Volume
31
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
DDE (4,4'-) decrease eggshell thickness Female Adult 8/group 6 mg/kg bw/d TOX-REPRO - physiology NR diet Toxicity Factor Datasets
DDE (4,4'-) decrease Calcium ATPase activity of shell gland Female Adult 8/group 6 mg/kg bw/d TOX-REPRO - physiology NR diet Toxicity Factor Datasets
DDE (4,4'-) decrease carbonic anhydrase activity of shell gland Female Adult 8/group 6 mg/kg bw/d TOX-REPRO - physiology NR diet Toxicity Factor Datasets
DDE (4,4'-) no effect calcium concentration in blood Female Adult 8/group 6 mg/kg bw/d TOX-REPRO - physiology NR diet Toxicity Factor Datasets
Citation:

DDE-induced eggshell thinning in the American kestrel: A comparison of the field situation and laboratory results

Author(s)
Lincer, Jeffrey L.
Pages
781-793
Year
Issue
3
Volume
12
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
DDE (4,4'-) decrease at all doses (15.1-29.2%) eggshell thickness Female Adult 2-5 pairs/dose 0, 0.3, 3, 6, 10 ppm (wet wt) TOX-REPRO - physiology 6 mo diet Toxicity Factor Datasets
Citation:

Organochlorine contaminants in a terrestrial foodweb on the Niagara Peninsula, Ontario, Canada 1987 - 89

Author(s)
Hebert, C.E., D.V. Weseloh, L. Kot and V. Glooschenko
Pages
356-366
Year
Volume
26
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Location Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
DDE (4,4'-) 5.53 mg/kg egg (wet wt) mean DDE concentration in eggs (pooled analyses) Both Male and Female Embryo N. Niagra Peninsula, Ontario 10 eggs 0.009 mg/kg plant; 0.343 mg/kg soil; 0.605 mg/kg worm; 0.016 mg/kg vole TOX-EXP IND - accumulation NR diet Toxicity Factor Datasets
Citation:

Eggshell thickness and reproduction in American kestrels exposed to chronic dietary lead

Author(s)
Pattee, Oliver H.
Pages
29-34
Year
Volume
13
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
LEAD (elemental) no effect eggshell thickness Female Adult 16 pairs/group 0, 10, 50 ppm TOX-REPRO - physiology 5-7 mo diet Toxicity Factor Datasets
LEAD (elemental) no effect lead concentration in eggshell Female Adult 16 pairs/group 0, 10, 50 ppm TOX-EXP IND - accumulation 5-7 mo diet Toxicity Factor Datasets
LEAD (elemental) 62.0 ppm tibia, 13.5 ppm humeri at 50 ppm lead concentrations in bones Female Adult 16 pairs/group 0, 10, 50 ppm TOX-EXP IND - accumulation 5-7 mo diet Toxicity Factor Datasets
Citation:

Methyl parathion and fenvalerate toxicity in American kestrels: acute physiological responses and effects of cold

Author(s)
Rattner, Barnett A. and J. Christian Franson
Pages
787-792
Year
Volume
62
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
METHYLPARATHION increased at 2, 3 mg/kg bw abnormal posture, ataxia, paresis Both Male and Female Adult 5/dose 0, 0.375, 1.0, 2.0, 3.0 mg/kg bw TOX-Non-Repro-Sublethal - behavioral effects single gavage Toxicity Factor Datasets
METHYLPARATHION increase at 3 mg/kg bw mortality rate 2 hr post-dose Both Male and Female Adult 5/dose 0, 0.375, 1.0, 2.0, 3.0 mg/kg bw TOX-MORT - dose-response data single gavage Toxicity Factor Datasets
METHYLPARATHION decrease at 2, 3 mg/kg bw cloacal temperature Both Male and Female Adult 5/dose 0, 0.375, 1.0, 2.0, 3.0 mg/kg bw TOX-Non-Repro-Sublethal - whole animal single gavage Toxicity Factor Datasets
METHYLPARATHION decrease at 2, 3 mg/kg bw plasma cholinesterase activity 2 hr post-dose Both Male and Female Adult 5/dose 0, 0.375, 1.0, 2.0, 3.0 mg/kg bw TOX-EXP IND - biomarkers single gavage Toxicity Factor Datasets
METHYLPARATHION decrease at 1, 2, 3 mg/kg bw brain acetylcholinesterase activity 10 hr post-dose Both Male and Female Adult 5/dose 0, 0.375, 1.0, 2.0, 3.0 mg/kg bw TOX-Non-Repro-Sublethal - cellular/biochemical effects single gavage Toxicity Factor Datasets
METHYLPARATHION increased at 2, 3 mg/kg bw plasma glucose concentrations Both Male and Female Adult 5/dose 0, 0.375, 1.0, 2.0, 3.0 mg/kg bw TOX-Non-Repro-Sublethal - cellular/biochemical effects single gavage Toxicity Factor Datasets
Citation:

Prey-Capturing Ability of American Kestrels Fed DDE and Acephate or Acephate Alone

Author(s)
Rudolph, S. G., J. G. Zinkl, D. W. Anderson and P. J. Shea
Pages
367-372
Year
Volume
13
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
ACEPHATE, DDE (4,4'-) no effect prey capturing behavior Not Reported Adult 5-6/group 50 mg acephate/kg bw +/- 6 ppm DDE (wet wt) TOX-Non-Repro-Sublethal - behavioral effects single (acephate) chronic (DDE) diet Toxicity Factor Datasets
ACEPHATE, DDE (4,4'-) decrease for both treatments median serum cholinesterase activity 24 hr post-dose Not Reported Adult 5-6/group 50 mg acephate/kg bw +/- 6 ppm DDE (wet wt) TOX-EXP IND - biomarkers single (acephate) chronic (DDE) diet Toxicity Factor Datasets

Anas platyrhynchos

Citation:

Toxicity of Zectran insecticide to several wildlife species

Author(s)
Tucker, Richard K. and D. Glen Crabtree
Pages
1307-1310
Year
Issue
6
Volume
62
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
MEXACARBATE 3.0 mg/kg LD50 Both Male and Female Not Reported 12 NR TOX-MORT - toxicity benchmarks single gavage Toxicity Factor Datasets

Zenaida macroura

Citation:

Toxicity of Zectran insecticide to several wildlife species

Author(s)
Tucker, Richard K. and D. Glen Crabtree
Pages
1307-1310
Year
Issue
6
Volume
62
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
MEXACARBATE 2.83 mg/kg LD50 Both Male and Female Not Reported 8 NR TOX-MORT - toxicity benchmarks single gavage Toxicity Factor Datasets

Peromyscus maniculatus

Citation:

Effects of range treatment with 2,4-D on rodent populations

Author(s)
Johnson, Donald R. and Richard M. Hansen
Pages
125-132
Year
Issue
1
Volume
33
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Location Sample Size Tox Exposure Toxicity Endpoint Type Tox Exposure Duration Tox Exposure Technique Type
DICHLOROPHENOXY-ACETIC ACID (2,4-) no effect changes in population density; treated versus control site Not Reported Both Adults and Juveniles Gunnison County and Saquache County, (elev., 8500 - 9300 ft.) 6 study areas/dose 0, 2-3 lbs/acre TOX-POP - size effects single field application Toxicity Factor Datasets
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