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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CHLORDANE | 8,906 ppb, range; 4,954 - 15, 609 ppb | mean and range of total technical chlordane residues in newt carcasses (without liver and stomach) 14 days after application | Both Male and Female | Both Adults and Juveniles | 4 | aerial application; water residues, 4.6 ppb (day 7), 0.29 ppb (day 52), 0.009 ppb (day 421); sediment residues, 35 ppb (day 7), 34 ppb (day 52), 20 ppb (day 1014) | TOX-EXP IND - accumulation | 14 d | field application | Toxicity Factor Datasets |
CHLORDANE | 2,116 ppb, range; 1,354 - 3,783 ppb | mean and range of total technical chlordane residues in newt carcasses (without liver and stomach) 451 days after application | Both Male and Female | Both Adults and Juveniles | 6 | aerial application; water residues, 4.6 ppb (day 7), 0.29 ppb (day 52), 0.009 ppb (day 421); sediment residues, 35 ppb (day 7), 34 ppb (day 52), 20 ppb (day 1014) | TOX-EXP IND - accumulation | 451 d | field application | Toxicity Factor Datasets |
CHLORDANE | 176 ppb, range; 29 - 272 ppb | mean and range of total technical chlordane residues in newt carcasses (without liver and stomach) 1036 days after application | Both Male and Female | Both Adults and Juveniles | 8 | aerial application; water residues, 4.6 ppb (day 7), 0.29 ppb (day 52), 0.009 ppb (day 421); sediment residues, 35 ppb (day 7), 34 ppb (day 52), 20 ppb (day 1014) | TOX-EXP IND - accumulation | 1036 d | field application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AZINPHOS-METHYL (GUTHION) | 3.77 mg/l (95% CI; 1.82 - 4.22) | LC50 | Not Reported | Tadpole | 10 tadpoles/replicate; 2 replicates/dose; 5 doses | 0.01-9.67 mg/l | TOX-MORT - toxicity benchmarks | 8 d | waterborne | Toxicity Factor Datasets |
AZINPHOS-METHYL (GUTHION) | 1.78 mg/l | NOAEL | Not Reported | Tadpole | 10 tadpoles/replicate; 2 replicates/dose; 5 doses | 0.01-9.67 mg/l | TOX-MORT - toxicity benchmarks | 8 d | waterborne | Toxicity Factor Datasets |
AZINPHOS-METHYL (GUTHION) | 9.67 mg/l | LOAEL | Not Reported | Tadpole | 10 tadpoles/replicate; 2 replicates/dose; 5 doses | 0.01-9.67 mg/l | TOX-MORT - toxicity benchmarks | 8 d | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIURON | 15.2 mg/l | 14-d LC50 value; mean of 2 tests | Not Reported | Tadpole | 8/replicate; 3 replicates/dose | 0, 0.5, 1.0, 3.8, 7.6, 14.5, 21.1, 29.1 mg/l | TOX-MORT - toxicity benchmarks | 14 d | waterborne | Toxicity Factor Datasets |
DIURON | 14.5 mg/l | lowest NOAEL based on body length/weight endpoints | Not Reported | Tadpole | 8/replicate; 3 replicates/dose | 0, 0.5, 1.0, 3.8, 7.6, 14.5, 21.1, 29.1 mg/l | TOX-Non-Repro-Sublethal - whole animal | 14 d | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Error | Units | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|---|
AMMONIUM NITRATE | 25.0 | 10-d LC50 value for embryos | 21.9-28.7 (95% CI) | mg/L as NH4-N | Not Reported | Embryo | 10/replicate; 3 replicates/dose | 0.3, 3.3, 6.9, 13.3, 25.1, 50.9, 101.2 mg/L NH4-N, mean measured concentration | TOX-MORT - toxicity benchmarks | 10 d | waterborne | Toxicity Factor Datasets |
AMMONIUM NITRATE | 6.9 | LOAEL for body weight and length | mg NH4-N/L | Not Reported | Embryo | 10/replicate; 3 replicates/dose | 0.3, 3.3, 6.9, 13.3, 25.1, 50.9, 101.2 mg/L NH4-N, mean measured concentration | TOX-REPRO - development | 10 d | waterborne | Toxicity Factor Datasets | |
AMMONIUM NITRATE | 3.3 | NOAEL for body weight and length | mg NH4-N/L | Not Reported | Embryo | 10/replicate; 3 replicates/dose | 0.3, 3.3, 6.9, 13.3, 25.1, 50.9, 101.2 mg/L NH4-N, mean measured concentration | TOX-REPRO - development | 10 d | waterborne | Toxicity Factor Datasets | |
AMMONIUM CHLORIDE | 30.3 | 10-d LC50 for embryos | 27.0 - 33.4 (95% CI) | mg NH4-N/L | Not Reported | Embryo | 10/replicate; 3 replicates/dose | 0.2, 2.8, 7.3, 12.8, 24.9, 49.7, 102.9 mg/L NH4-N, mean measured concentration | TOX-MORT - toxicity benchmarks | 10 d | waterborne | Toxicity Factor Datasets |
AMMONIUM CHLORIDE | 24.9 | LOAEL for body weight and length and deformities | mg NH4-N/L | Not Reported | Embryo | 10/replicate; 3 replicates/dose | 0.2, 2.8, 7.3, 12.8, 24.9, 49.7, 102.9 mg/L NH4-N, mean measured concentration | TOX-REPRO - development | 10 d | waterborne | Toxicity Factor Datasets | |
AMMONIUM CHLORIDE | 12.8 | NOAEL for body weight and length and deformities | mg NH4-N/L | Not Reported | Embryo | 10/replicate; 3 replicates/dose | 0.2, 2.8, 7.3, 12.8, 24.9, 49.7, 102.9 mg/L NH4-N, mean measured concentration | TOX-REPRO - development | 10 d | waterborne | Toxicity Factor Datasets | |
AMMONIUM SULFATE | 32.4 | 10-d LC50 for embryos | 29.7 - 35.4 (95% CI) | mg NH4-N/L | Not Reported | Embryo | 10/replicate; 3 replicates/dose | 0.04, 2.6, 6.1, 11.7, 23.1, 45.4, 91.5 mg/L NH4-N, mean measured concentration | TOX-MORT - toxicity benchmarks | 10 d | waterborne | Toxicity Factor Datasets |
AMMONIUM SULFATE | 11.7 | LOAEL for body weight | mg NH4-N/L | Not Reported | Embryo | 10/replicate; 3 replicates/dose | 0.04, 2.6, 6.1, 11.7, 23.1, 45.4, 91.5 mg/L NH4-N, mean measured concentration | TOX-REPRO - development | 10 d | waterborne | Toxicity Factor Datasets | |
AMMONIUM SULFATE | 6.1 | NOAEL for body weight | mg NH4-N/L | Not Reported | Embryo | 10/replicate; 3 replicates/dose | 0.04, 2.6, 6.1, 11.7, 23.1, 45.4, 91.5 mg/L NH4-N, mean measured concentration | TOX-REPRO - development | 10 d | waterborne | Toxicity Factor Datasets | |
NITRATE, SODIUM | 578.0 | 10-d LC50 for embryos | 459.0 - 726.5 (95% CI) | mg NO3-N/L | Not Reported | Embryo | 10/replicate; 3 replicates/dose | 0.1, 24.8, 56.7, 111.0, 230.4, 470.4, 979.2, 2716 mg/L NO3-N, mean measured concentration | TOX-MORT - toxicity benchmarks | 10 d | waterborne | Toxicity Factor Datasets |
NITRATE, SODIUM | 111.0 | LOAEL for body weight and length | mg NO3-N/L | Not Reported | Embryo | 10/replicate; 3 replicates/dose | 0.1, 24.8, 56.7, 111.0, 230.4, 470.4, 979.2, 2716 mg/L NO3-N, mean measured concentration | TOX-REPRO - development | 10 d | waterborne | Toxicity Factor Datasets | |
NITRATE, SODIUM | 56.7 | NOAEL for body weight and length | mg NO3-N/L | Not Reported | Embryo | 10/replicate; 3 replicates/dose | 0.1, 24.8, 56.7, 111.0, 230.4, 470.4, 979.2, 2716 mg/L NO3-N, mean measured concentration | TOX-REPRO - development | 10 d | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
FLUORANTHENE | increase @ 10.97 - 59.48 ug/l | incidence of structural disorganization and necrosis of the integument | Not Reported | Tadpole | 20/group | 0, 10.97, 37.97, 59.48 ug/l with simulated solar UV radiation | TOX-Non-Repro-Sublethal - organ/system effects | 96 hr | water-borne; flow-through | Toxicity Factor Datasets |
FLUORANTHENE | increase @ 37.97 ug/l | total distance travelled | Not Reported | Tadpole | 20/group | 0, 10.97, 37.97, 59.48 ug/l with simulated solar UV radiation | TOX-Non-Repro-Sublethal - behavioral effects | 96 hr | water-borne; flow-through | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIURON | 12.7 mg/l (95% CI; 9.8 - 16.4) | 21 d LC50 | Not Reported | Tadpole | 5/replicate; 3 replicates/dose | 0, 0.5, 1.0, 3.8, 7.6, 14.5, 21.1, 29.1 mg/l | TOX-MORT - toxicity benchmarks | 21 d | waterborne | Toxicity Factor Datasets |
DIURON | 7.6 mg/l | lowest NOAEL based on body weight endpoint | Not Reported | Tadpole | 5/replicate; 3 replicates/dose | 0, 0.5, 1.0, 3.8, 7.6, 14.5, 21.1, 29.1 mg/l | TOX-Non-Repro-Sublethal - whole animal | 21 d | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Range | Units | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|---|
MERCURIC CHLORIDE | 63.36 | 96 hour LC50 (95% Confidence Interval); based on measured concentrations | 37.02 - 108.30 (95% CI) | ug Hg/L | Not Reported | Not Reported | 10/dose | 0, 1.4, 3.9, 12.0, 110.0 and 487 ug Hg/L (mean daily measured concn.) | TOX-MORT - toxicity benchmarks | 96 hr | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Units | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|---|
ARSENIC COMPOUNDS, CADMIUM COMPOUNDS, CHROMIUM COMPOUNDS, COPPER COMPOUNDS, SELENIUM COMPOUNDS | increase at contaminated, relative to reference site | resting oxygen consumption at 25C, measured in the lab | ml O2/hr/tadpole | Not Reported | Tadpole | Savannah River | 8-11 | 80-d tadpole residue levels (ppm dry wt) at contaminated (C) vs reference (R) sites: Chromium, C=27.25 +/- 6.22, R=8.58 +/- 0.35; Copper, C=55.12 +/- 5.05, R=17.40 +/- 1.74; Arsenic C=25.95 +/- 3.08, R=0.75 +/- 0.20; Selenium, C=25.27 +/- 1.67, R=0.83 +/- | TOX-Non-Repro-Sublethal - whole animal | NR | site contamination | Toxicity Factor Datasets |
ARSENIC COMPOUNDS, CADMIUM COMPOUNDS, CHROMIUM COMPOUNDS, COPPER COMPOUNDS, SELENIUM COMPOUNDS | decrease at contaminated, compared to reference site | % survival to 80 d posthatching | % | Not Reported | Tadpole | Savannah River | Not Reported | 80-d tadpole residue levels (ppm dry wt) at contaminated (C) vs reference (R) sites: Chromium, C=27.25 +/- 6.22, R=8.58 +/- 0.35; Copper, C=55.12 +/- 5.05, R=17.40 +/- 1.74; Arsenic C=25.95 +/- 3.08, R=0.75 +/- 0.20; Selenium, C=25.27 +/- 1.67, R=0.83 +/- | TOX-REPRO - reproductive success | NR | site contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
METHYLPARATHION | 79.5 | in loco heart rate | Not Reported | Tadpole | NR | 36 | 10 µg/L | TOX-MORT - dose-response data | 48 h | Toxicity Factor Datasets | |
PENOXSULAM | 7.52 mg/L | LC50 | Not Reported | Tadpole | Experimental Frog Farm, São Paulo | 6 | (+ vegetable oil adjuvant): 2.88 + 55.80; 4.32 + 83.70; 5.76 + 111.60; 7.20 mg/L C 139.50; 8.64 + 167.40 | TOX-MORT - toxicity benchmarks | 96 hr | Waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIURON | 22.2 mg/l (95% CI; 19.8 - 25.0) | 14 d LC50 | Not Reported | Tadpole | 5/replicate; 3 replicates/dose | 0, 0.5, 1.0, 3.8, 7.6, 14.5, 21.1, 29.1 mg/l | TOX-MORT - toxicity benchmarks | 14 d | waterborne | Toxicity Factor Datasets |
DIURON | 7.6 mg/l | lowest NOAEL based on body weight endpoint | Not Reported | Tadpole | 5/replicate; 3 replicates/dose | 0, 0.5, 1.0, 3.8, 7.6, 14.5, 21.1, 29.1 mg/l | TOX-Non-Repro-Sublethal - whole animal | 14 d | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|
IRON SULFATE | increase @ 30-288 mg/l | Not Reported | Juvenile | 5-25/dose | 0, 3, 10, 20, 30, 35, 40, 72, 144, 288 mg/l Fe++ | TOX-MORT - dose-response data | 39 d | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
METHOXYCHLOR | no appreciable mortality | embryo and larvae (10 d post-hatch) mortality | Not Reported | Embryo, Juvenile | 30-34 eggs/dose | 0, 0.03, 0.1, 0.3, 1.0, 3.2, 10.0 mg/L (DMSO carrier) | TOX-MORT - dose-response data | 45 d | waterborne | Toxicity Factor Datasets |
METHOXYCHLOR | decrease @ 0.1, 0.3, 1, 3, 10 mg/L | mean day of hatch, compared to controls | Not Reported | Embryo, Juvenile | 30-34 eggs/dose | 0, 0.03, 0.1, 0.3, 1.0, 3.2, 10.0 mg/L (DMSO carrier) | TOX-REPRO - development | 35 d | waterborne | Toxicity Factor Datasets |
METHOXYCHLOR | decrease @ 0.3, 1, 3, 10 mg/l | responsiveness to startle and distance travelled post-startle in larvae | Not Reported | Juvenile | 30-34 eggs exposed/dose; 14-27 larvae tested/dose | 0, 0.03, 0.1, 0.3, 1.0, 3.2, 10.0 mg/L (DMSO carrier) | TOX-REPRO - behavior | 45 d | waterborne | Toxicity Factor Datasets |
METHOXYCHLOR | decrease @ 0.3 and 10 mg/L | mean body weight of larvae | Not Reported | Embryo, Juvenile | 30-38 eggs/dose | 0, 0.03, 0.1, 0.3, 1.0, 3.2, 10.0 mg/L (DMSO carrier) | TOX-Non-Repro-Sublethal - whole animal | 37 d | waterborne | Toxicity Factor Datasets |
Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
no effect | capture rates between logged and burned units and the logged, burned and sprayed units during the year after spraying | Not Reported | Not Reported | Oregon Coast Range | 3 units/treatment | control or 1.3 kg/ha | TOX-POP - size effects | single | field application | Toxicity Factor Datasets |