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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | lead only: 3.53 (+/- 1.43); lead-iron: 1.42 (+/- 0.65) ppm, wet wt | lead concentration in kidneys (mean +/- SE) | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | 0, 1 #four lead shot, or 1 #four iron-lead shot (47.5% lead) | TOX-EXP IND - accumulation | single | intubation | Toxicity Factor Datasets |
LEAD (elemental) | lead only: 1.02 (+/- 0.22); lead-iron: 0.75 (+/- 0.10) ppm, wet wt | lead concentration in kidneys (mean +/- SE) | Male | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | 0, 1 #four lead shot, or 1 #four iron-lead shot (47.5% lead) | TOX-EXP IND - accumulation | single | intubation | Toxicity Factor Datasets |
LEAD (elemental) | lead only: 1.15 (+/- 0.29); lead-iron: 0.32 (+/- 0.05) ppm, wet wt | lead concentration in liver (mean +/- SE) | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | 0, 1 #four lead shot, or 1 #four iron-lead shot (47.5% lead) | TOX-EXP IND - accumulation | single | intubation | Toxicity Factor Datasets |
LEAD (elemental) | lead only: 0.58 (+/- 0.19); lead-iron: 0.25 (+/- 0.02) ppm, wet wt | lead concentration in liver (mean +/- SE) | Male | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | 0, 1 #four lead shot, or 1 #four iron-lead shot (47.5% lead) | TOX-EXP IND - accumulation | single | intubation | Toxicity Factor Datasets |
LEAD (elemental) | decreased with increasing lead in bone | number of eggs laid | Female | Adult | control=2 F, 4 M; treatment=6 M-F pairs/group | 0, 1 #four lead shot, or 1 #four iron-lead shot (47.5% lead) | TOX-REPRO - reproductive success | single | intubation | Toxicity Factor Datasets |
LEAD (elemental) | increased with lead shot (egg contents: 0.50 +/-0.06; egg shell: 2.80 +/-0.25 ppm, wet wt) and lead-iron shot (egg shell: 1.42 +/-0.26 ppm, wet wt) | lead in egg contents and shell (mean +/- SE) versus controls | Female | Adult | control=10 eggs; treatment=20 eggs | 0, 1 #four lead shot, or 1 #four iron-lead shot (47.5% lead) | TOX-EXP IND - accumulation | single | intubation | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD NITRATE | decreased @ 3,000, 30,000 ppm, incubation day 3 exposure | embyronic length and weight by incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | 0, 300, 3,000, 30,000 ppm lead in solution | TOX-REPRO - development | single 30 second exposure | egg immersion in solution | Toxicity Factor Datasets |
METHYLMERCURY CHLORIDE | decreased @ all doses | embryo length or weight by incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | 0, 50, 500, 5,000 ppm mercury in solution | TOX-REPRO - development | single 30 second exposure | egg immersion in solution | Toxicity Factor Datasets |
METHYLMERCURY CHLORIDE | decreased @ 5,000 ppm, incub. day 3 exposure | embryo survival through day 18 of incubation and % of survivors that were normal versus controls | Not Reported | Embryo | 30 eggs/group | 0, 50, 500, 5,000 ppm mercury in solution | TOX-REPRO - development | single 30 second exposure | egg immersion in solution | Toxicity Factor Datasets |
FUEL OILS | decreased @ 0.5, 5 ul/egg on incubation day 3 or 8 | embryo survival to day 18 of incubation and % of survivors that were normal versus controls | Not Reported | Embryo | 30 eggs/group | 0, 0.5, 5 ul RDCO oil/egg | TOX-REPRO - development | single | topical application | Toxicity Factor Datasets |
FUEL OILS | decreased @ 0.5 ul/egg, incubation day 3 or 8 exposure | embyronic length and weight by incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | 0, 0.5, 5 ul RDCO oil/egg | TOX-REPRO - development | single | topical application | Toxicity Factor Datasets |
FUEL OILS | decreased @ 2% emulsion, incubation day 8 exposure | embryo survival through day 18 of incubation versus controls | Not Reported | Embryo | 30 eggs/group | 0, 0.2%, 2% aqueous spray oil emulsion | TOX-REPRO - development | single 30 second exposure | egg immersion | Toxicity Factor Datasets |
ACETONE | decreased @ 100% solution, incubation days 3 or 8 exposure | embryo weight and length by incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | 0, 10%, 100% solution | TOX-REPRO - development | single 30 second exposure | egg immersion | Toxicity Factor Datasets |
ACETONE | decreased @ 100% solution, incubation days 3 or 8 exposure | embryo survival through incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | 0, 10%, 100% solution | TOX-REPRO - development | single 30 second exposure | egg immersion | Toxicity Factor Datasets |
N-BUTYL ALCOHOL | 0 survival @ 100% solution, incubation days 3 or 8 exposure | embryo survival through incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | 0, 10%, 100% solution | TOX-REPRO - development | single 30 second exposure | egg immersion | Toxicity Factor Datasets |
XYLENE | no effect | embryo survival, size, and incidence of abnormalities through incubation day 18 versus controls | Not Reported | Embryo | 30 eggs/group | 0, 1%, 10% solution | TOX-REPRO - development | single 30 second exposure | egg immersion | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD NITRATE | decreased @ 25 ppm/3 wks, 5 ppm/12 wks | delta-aminolevulinic acid dehydratase activity in blood versus controls | Male | Adult | 20/dose; 5/dose x time group | 0, 1, 5, 25 ppm diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 3, 6, 9, or 12 wks | diet | Toxicity Factor Datasets |
LEAD NITRATE | increased @ 25 ppm/3wks | accumulation in livers and kidneys versus controls | Male | Adult | 20/dose; 5/dose x time group | 0, 1, 5, 25 ppm diet | TOX-EXP IND - accumulation | 3, 6, 9, or 12 wks | diet | Toxicity Factor Datasets |
LEAD NITRATE | increased @ 5 ppm diet (66 +/-13 ppm blood) and @ 25 ppm diet (154 +/-28 ppm blood) | lead concentration in blood after 12 weeks exposure (mean +/- SE) versus controls | Male | Adult | 20/dose; 5/dose x time group | 0, 1, 5, 25 ppm diet | TOX-EXP IND - accumulation | 3, 6, 9, or 12 wks | diet | Toxicity Factor Datasets |
LEAD NITRATE | no effect | body weight and food consumption versus controls | Male | Adult | 20/group | 0, 1, 5, 25 ppm diet | TOX-Non-Repro-Sublethal - whole animal | 3, 6, 9, or 12 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | increased in all groups dosed with lead shot | incidence of clinical signs, weight loss, breast muscle atrophy | Both Male and Female | Adult | treatment = 10/group control = 5 | 0, 4 #four lead shot; combined with commerical feed, Ca- supplemented corn diet, or corn only diet | TOX-Non-Repro-Sublethal - whole animal | single | intubation | Toxicity Factor Datasets |
LEAD (elemental) | increased with Pb/corn+Ca (50%), and Pb/corn only (100%) | % mortality versus controls | Both Male and Female | Adult | treatment = 10/group control = 5 | 0, 4 #four lead shot; combined with commerical feed, Ca- supplemented corn diet, or corn only diet | TOX-MORT - dose-response data | single | intubation | Toxicity Factor Datasets |
LEAD (elemental) | decreased in Pb/commerical (hemoglobin only), Pb/corn+Ca, and Pb/corn only | red blood cell counts, packed cell volume, hemoglobin concentration versus controls | Both Male and Female | Adult | treatment = 10/group control = 5 | 0, 4 #four lead shot; combined with commerical feed, Ca-supplemented corn diet, or corn only diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | intubation | Toxicity Factor Datasets |
LEAD (elemental) | increased with Pb/corn + Ca, Pb/corn only | blood protoporphyrin concentrations versus controls | Both Male and Female | Adult | treatment = 10/group control = 5 | 0, 4 #four lead shot; combined with commerical feed, Ca-supplemented corn diet, or corn only diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | intubation | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decreased @ 500, 1000, 5000 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | 0, 500, 1000, 5000 mg/kg bw | TOX-REPRO - physiology | single | intubation | Toxicity Factor Datasets |
AROCLOR 1254 | decreased @ 1000 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | 0, 1000 mg/kg bw | TOX-REPRO - physiology | single | intubation | Toxicity Factor Datasets |
CHLOROETHYLMERCURY | decreased @ 500 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | 0, 500 mg/kg bw | TOX-REPRO - physiology | single | intubation | Toxicity Factor Datasets |
DICHLOROPHENOXY-ACETIC ACID (2,4-) | decreased @ 1500 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | 0, 1500 mg/kg bw | TOX-REPRO - physiology | single | intubation | Toxicity Factor Datasets |
HEPTACHLOR | decreased @ 1000 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | 0, 1000 mg/kg bw | TOX-REPRO - physiology | single | intubation | Toxicity Factor Datasets |
ARSENITE, SODIUM | decreased @ 100 mg/kg bw | post-dose eggshell thickness versus pre-dose thickness | Female | Adult | 5/group | 0, 100 mg/kg bw | TOX-REPRO - physiology | single | intubation | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-), LEAD COMPOUNDS, MERCURY COMPOUNDS | decreased @ 40 ppm DDE | eggshell thickness versus controls | Female | Adult | 10/group | 0, 40 ppm DDE, 100 ppm lead, or 200 ppm N-(ethylmercury)-p-toluene sulfoanilide | TOX-REPRO - physiology | 55 d - approx. 2 mos | diet | Toxicity Factor Datasets |
DDE (4,4'-), LEAD COMPOUNDS, MERCURY COMPOUNDS | decreased with both treatments | eggshell thickness versus controls | Female | Adult | 10/group | 0, 40 ppm DDE + 100 ppm lead, or 40 ppm DDE + 200 ppm N-(ethylmercury)-p-toluene sulfoanilide | TOX-REPRO - physiology | 55 d - approx. 2 mos | diet | Toxicity Factor Datasets |
DDE (4,4'-) | 78.2 (carcass); 61.6 (egg); 4.1 (brain) ppm, wet wt | DDE residues in whole carcass, egg contents, and brain | Female | Adult | 10/group | 40 ppm DDE | TOX-EXP IND - accumulation | approx. 2 mos. | diet | Toxicity Factor Datasets |
MERCURY COMPOUNDS | 2.5 (carcass); 1.25 (egg); 23.7 (kidney) ppm, wet wt | mercury residues in whole carcass, egg contents, and kidneys | Female | Adult | 10/group | 200 ppm N-(ethylmercury)-p-toluene sulfoanilide | TOX-EXP IND - accumulation | 55 d | diet | Toxicity Factor Datasets |
LEAD COMPOUNDS | 3.7 (carcass); 2.5 (egg); 2.5 (eggshells); 9.6 (bone) ppm, wet wt @ 100 ppm lead; 3.4 (carcass); 0.88 (egg); 2.8 (eggshells); 35.0 (bone) ppm, wet wt @ 100 ppm lead + DDE | lead residues in whole carcass, egg contents, eggshells, and bone | Female | Adult | 10/group | 100 ppm lead, or 40 ppm DDE + 100 ppm lead | TOX-EXP IND - accumulation | approx. 2 mos | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | 0.822 (0.059-21.60) ppm wet wt | geometric mean liver concentration (range) | Not Reported | Not Reported | Ebro Delta Natural Park | 39 birds | 297,590 shot pellets/ha (in sediment) | TOX-EXP IND - accumulation | NR | site contamination | Toxicity Factor Datasets |
LEAD COMPOUNDS | 1.367 (<0.05-29.80) | geometric mean concentration in kidneys (range) | Not Reported | Not Reported | Ebro Delta Natural Park | 39 birds | 297,590 shot pellets/ha (in sediment) | TOX-EXP IND - accumulation | NR | site contamination | Toxicity Factor Datasets |
LEAD COMPOUNDS | humerus, 41.652 (8.20-211.6); spleen, 0.669 (0.128-2.397); pancreas, 3.295 (1.074-13.47); brain, 1.367 (0.120-117.1) | geometric mean concentrations (ranges) in humerus, spleen, pancreas, and brain | Not Reported | Not Reported | Ebro Delta Natural Park | 6-10 birds/tissue type | 297,590 shot pellets/ha (in sediment) | TOX-EXP IND - accumulation | NR | site contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE, LEAD CHLORIDE | 7.2 (0.9) ug Pb/g @ 100 ppm Pb; 104.8 (19.1) ug Pb/g @ 100 ppm Cd; 54.2 (3.7) ug Cd/g @ 50 ppm Cd + 50 ppm Pb (dry wt) | mean (SE) concentrations in liver | Male | Juvenile | 6-8 birds/dose | 0, 10 ppm Cd, 100 ppm Cd, 10 ppm Pb, 100 ppm Pb, 5 ppm Cd +5 ppm Pb, 50 ppm Cd + 50 ppm Pb | TOX-EXP IND - accumulation | 42 +/- 1 d | diet | Toxicity Factor Datasets |
CADMIUM CHLORIDE, LEAD CHLORIDE | 67.8 (12.4) @ 10 ppm Cd; 371.8 (22.3) @ 100 ppm Cd; 3.4 (0.6) @ 100 ppm Pb; 201.0 (26.9) @ 50 ppm Cd + 50 ppm Pb (ug/g, dry wt) | mean (SE) Cd concentrations in kidney | Male | Juvenile | 6-8 birds/dose | 0, 10 ppm Cd, 100 ppm Cd, 10 ppm Pb, 100 ppm Pb, 5 ppm Cd +5 ppm Pb, 50 ppm Cd + 50 ppm Pb | TOX-EXP IND - accumulation | 42 +/- 1 d | diet | Toxicity Factor Datasets |