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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | decreased | number of 14-day old ducklings per hen versus controls | Both Male and Female | Hatchling | 274-327, 69-167, and 26-113 for the 0, 10, and 40 ppm DDE groups | 0, 10, or 40 ppm | TOX-REPRO - reproductive success | 2 years | Diet | Toxicity Factor Datasets |
DDE (4,4'-) | increased | % cracked eggs versus controls | Female | Hatchling | 666-696, 620-664, and 317-602 for the 0, 10, and 40 ppm DDE groups | 0, 10, or 40 ppm | TOX-REPRO - physiology | 2 years | Diet | Toxicity Factor Datasets |
DDE (4,4'-) | decreased | eggshell thickness versus controls | Female | Adult | 20-28, 21-25, and 10-23 for the 0, 10, and 40 ppm DDE groups | 0, 10, or 40 ppm | TOX-REPRO - physiology | 2 years | Diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Range | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | 145 mg/kg | LD50 | 55.8 - 377 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
CHLORPYRIFOS | 29.4 mg/kg | LD50 | 18.6 - 46.7 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
CHLORPYRIFOS | 50.4 mg/kg | LD50 | 32.5 - 78.1 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
CHLORPYRIFOS | 83.3 mg/kg | LD50 | 44.0 - 158 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
ENDOSULFAN | 27.8 mg/kg | LD50 | 22.8 - 33.8 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
ENDOSULFAN | 6.47 mg/kg | LD50 | 5.19 - 8.05 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
ENDOSULFAN | 7.89 mg/kg | LD50 | 5.77 - 10.8 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
ENDOSULFAN | 34.4 mg/kg | LD50 | 26.1 - 45.3 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
ALDICARB | 1.92 mg/kg | LD50 | 1.55 - 2.37 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
ALDICARB | 3.60 mg/kg | LD50 | 2.90 - 4.49 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
ALDICARB | 6.73 mg/kg | LD50 | 5.29 - 8.55 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
ALDICARB | 4.44 mg/kg | LD50 | 3.49 - 5.65 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
PARATHION | 1.65 mg/kg | LD50 | 1.40 - 1.96 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
PARATHION | 1.44 mg/kg | LD50 | 1.13 - 1.83 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
PARATHION | 1.65 mg/kg | LD50 | 1.40 - 1.96 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
PARATHION | 2.34 mg/kg | LD50 | 1.98 - 2.78 (95% CI) | Both Male and Female | Juvenile | 5 | NR | TOX-MORT - toxicity benchmarks | Single exposure | Gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254, DDE (4,4'-) | decreased with all treatments | numbers of mammillary cores and basal caps on eggshell membranes versus controls | Female | Adult | 6-8 eggs/group from 10 hens | 0, 40 ppm DDE, 40 ppm Aroclor, 40 ppm DDE + 40 ppm Aroclor | TOX-REPRO - physiology | NR | Diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIELDRIN | decreased @ 10 ppm (serotonin only) and 30 ppm | Serotonin, norepinephrine, and dopamine levels versus controls | Both Male and Female | Juvenile | 3-6 per group | 0, 4, 10, and 30 ppm Dieldrin | TOX-Non-Repro-Sublethal - cellular/biochemical effects | Second - generation. Exposed 75 days after hatch. | Diet | Toxicity Factor Datasets |
DIELDRIN | increased with all doses | brain, liver, and adipose dieldrin concentrations | Both Male and Female | Juvenile | 4-6 per group | 0, 4, 10, and 30 ppm Dieldrin | TOX-EXP IND - accumulation | Second - generation. Exposed 75 days after hatch. | Diet | Toxicity Factor Datasets |
DIELDRIN | no effect | bw versus controls | Both Male and Female | Juvenile | 9-25 per group | 0, 4, 10, and 30 ppm Dieldrin | TOX-Non-Repro-Sublethal - organ/system effects | Second - generation. Exposed 75 days after hatch. | Diet | Toxicity Factor Datasets |
DIELDRIN | increased @ 10 ppm (liver only), 30 ppm (brain only) | brain and liver weight to body weight ratios versus controls | Both Male and Female | Juvenile | 9-25 per group | 0, 4, 10, and 30 ppm Dieldrin | TOX-Non-Repro-Sublethal - organ/system effects | Second - generation. Exposed 75 days after hatch. | Diet | Toxicity Factor Datasets |
DIELDRIN | increased@ 4, 10, 30 ppm | hepatic microsomal enzyme activity versus controls | Both Male and Female | Juvenile | 5-15 per group | 0, 4, 10, and 30 ppm Dieldrin | TOX-Non-Repro-Sublethal - cellular/biochemical effects | Second - generation. Exposed 75 days after hatch. | Diet | Toxicity Factor Datasets |
DIELDRIN | increased @ 30 ppm | liver protein concentration versus controls | Both Male and Female | Juvenile | 5-15 per group | 0, 4, 10, and 30 ppm Dieldrin | TOX-Non-Repro-Sublethal - cellular/biochemical effects | Second - generation. Exposed 75 days after hatch. | Diet | Toxicity Factor Datasets |
DIELDRIN | increased @ 10, 30 ppm | liver DNA content versus controls | Male | Both Adults and Juveniles | 5-15 per group | 0, 4, 10, and 30 ppm Dieldrin | TOX-Non-Repro-Sublethal - cellular/biochemical effects | Second - generation. Exposed 75 days after hatch. | Diet | Toxicity Factor Datasets |
DIELDRIN | decreased @ all doses | % drake encounter scores | Male | Both Adults and Juveniles | 30 per group | 0, 4, 10, and 30 ppm Dieldrin | TOX-Non-Repro-Sublethal - behavioral effects | Second - generation. Exposed 75 days after hatch. | Diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDT (4,4'-) | decreased | eggshell thickness versus controls | Female | Adult | 5 hens; 19 eggs | 0, 50 ppm | TOX-REPRO - physiology | 6 months | Diet | Toxicity Factor Datasets |
DDT (4,4'-) | decreased | eggshell weight versus controls | Female | Adult | 5 hens; 19 eggs | 0, 50 ppm | TOX-REPRO - physiology | 6 months | Diet | Toxicity Factor Datasets |
DDT (4,4'-) | decreased | eggshell quality (R-value) versus controls | Female | Adult | 5 hens; 19 eggs | 0, 50 ppm | TOX-REPRO - physiology | 6 months | Diet | Toxicity Factor Datasets |
DDT (4,4'-) | no effect | calcium concentration in eggshell versus controls | Female | Adult | 5 hens; 19 eggs | 0, or 50 ppm DDT | TOX-REPRO - physiology | 6 months | Diet | Toxicity Factor Datasets |
DDT (4,4'-) | no effect | total Ca/eggshell | Female | Adult | 5 hens; 19 eggs | 0, or 50 ppm | TOX-REPRO - physiology | 6 months | Diet | Toxicity Factor Datasets |
DDT (4,4'-) | no effect | Ca - ATPase activity in eggshell glands versus controls | Female | Adult | 5 hens; 19 eggs | 0, or 50 ppm | TOX-REPRO - physiology | 6 months | Diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY | See citation Figures 3 & 4 | Blood concentration | Both Male and Female | Not Reported | Gambinini Marsh, Mid-Petaluma Marsh, Black John Slough | 64 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets |
METHYLMERCURY | See citation Figures 3 & 4 | Feather concentration | Not Reported | Gambinini Marsh, Mid-Petaluma Marsh, Black John Slough | 127 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
MERCURY (elemental) | 0.81 ± 0.50 µg/g dw | Feather concentration | Both Male and Female | Nestling | Georgia & South Carolina | 10 | NR | TOX-EXP IND - accumulation | Environmental Contamination | Toxicity Factor Datasets |
METHYLMERCURY | Review, see citation Figure 2 | Egg concentration | Embryo | Not reported | NR | TOX-EXP IND - accumulation | Toxicity Factor Datasets | |||
METHYLMERCURY | Review, see ciation Figure 3 | Feather concentration | Not Reported | Not reported | NR | TOX-EXP IND - accumulation | Toxicity Factor Datasets | |||
DDE (2,4'-) | 4.8 ppm ww | Egg concentration | Embryo | Blackfoot Reservoir | 9 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets |