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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
MERCURY (elemental), POLYCHLORINATED BIPHENYLS | 0.28 ppm wet wt mercury | concentration in liver | Not Reported | Nestling | Lake Pointsett, Dry Lake | 5 birds | <0.05-0.11 PCBs, <0.05-0.11 mercury, 0.016-0.092 OC insecticides; ppm (wet wt) in fish | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
MERCURY (elemental), POLYCHLORINATED BIPHENYLS | 7.98 ppm wet wt mercury | concentration in liver | Both Male and Female | Adult | Lake Pointsett, Dry Lake | 5 birds | <0.05-0.11 PCBs, <0.05-0.11 mercury, 0.016-0.092 OC insecticides; ppm (wet wt) in fish | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
CADMIUM (elemental), MERCURY (elemental) | no correlation | correlation of mean metallothionein concentration (13.2-24.4 ug/g tissue) and metal concentrations in kidneys | Not Reported | Both Adults and Juveniles | Heron Is., Manawagonish Is., Ile aux pommes | 24 birds | 0.03-6.3 ug Cd/g kidney, 0.77-12.9 ug Hg/g kidney, dry wt | TOX-EXP IND - biomarkers | NR | NR | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
POLYCHLORINATED BIPHENYLS | positive correlation | correlation of embryo mortality with TCDD equivalents in eggs | Not Reported | Embryo | Great Lakes | 11 colonies @ 25-50 nests/colony | 35-344 pg TCDD eq/g wet wt | TOX-REPRO - reproductive success | NR | in ovo | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), POLYCHLORINATED BIPHENYLS | 28.8% decrease | mean thickness of eggshells collected in 1969 compared with pre-1946 museum specimens | Female | Adult | Anacapa Island | 17 eggs | 754 ppm DDE, 87 ppm PCBs, 2.1 ppm DDD, 7.0 ppm DDT in egg yolk lipids | TOX-REPRO - physiology | NR | parent diet | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), POLYCHLORINATED BIPHENYLS | 38.3% decrease | mean thickness of eggshells collected in 1969 compared with pre-1946 museum specimens | Female | Adult | Los Coronados Island | 23 eggs | 574 ppm DDE, 422 ppm PCBs, 13.8 ppm DDD, 5.5 ppm DDT in egg yolk lipids | TOX-REPRO - physiology | NR | parent diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
POLYCHLORINATED BIPHENYLS | increased at 400, 800 ug/kg egg | incidence of embryo mortality versus controls | Not Reported | Embryo | 15-60/group | 0,5,10,25,50,100,200,400,800 ug/kg egg | TOX-REPRO - reproductive success | incubation period | egg injection | Toxicity Factor Datasets |
POLYCHLORINATED BIPHENYLS | increased at 5 ug/kg egg | weights of heart, liver and spleen versus controls | Not Reported | Hatchling | 8-29/group | 0,5,10,25,50,100,200,400,800 ug/kg egg | TOX-REPRO - development | incubation period | egg injection | Toxicity Factor Datasets |
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | increased at 4.0 ug/kg egg | incidence of embryo mortality versus controls | Not Reported | Hatchling | 58-60/group | 0,0.06,0.25,1.0,4.0 ug/kg egg | TOX-REPRO - reproductive success | incubation period | egg injection | Toxicity Factor Datasets |
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | no effect | weight of brain, heart, liver and spleen versus controls | Not Reported | Hatchling | Not Reported | 0,0.06,0.25,1.0,4.0 ug/kg egg | TOX-REPRO - development | incubation period | egg injection | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
POLYCHLORINATED BIPHENYLS | decreased compared with reference | hatching success (# hatched/# eggs) | Both Male and Female | Hatchling | Spider Is., Lake Michigan | 466 and 953 nests (2 yrs) | 7.34-8.22 ug/g egg (1.03 ug/g egg, reference site) | TOX-REPRO - reproductive success | NR | in ovo | Toxicity Factor Datasets |
POLYCHLORINATED BIPHENYLS | decreased compared with reference | clutch size | Female | Adult | Spider Is., Lake Michigan | 466 and 953 nests (2 yrs) | 7.34-8.22 ug/g egg (1.03 ug/g egg, reference site) | TOX-REPRO - physiology | NR | in ovo | Toxicity Factor Datasets |
POLYCHLORINATED BIPHENYLS | increased compared with reference | proportion of nestlings with bill defects | Both Male and Female | Hatchling | Spider Is., Lake Michigan | 1,511 and 2,700 chicks (2 yrs) | 7.34-8.22 ug/g egg (1.03 ug/g egg, reference site) | TOX-REPRO - physiology | NR | in ovo | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Range | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|---|
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | 31.3 | mean biomagnification factor for eggs from forage fish | 11.7-56.8 | Female | Adult | 12 eggs/site x 5 sites | 5.8-24.4 pgTCDD equivalents/g fish, wet wt, (5 sites) | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets | |
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | 162.4 pg/g bw gained (wet wt) | pg TCDD equivalents accumulated per gram of body weight gained (from eggs to largest chicks) | Not Reported | Nestling | Green Bay, Lake Michigan | 20 chicks | 24.4 pg TCDD equivalents/g fish, wet wt | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets | |
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | 100.4 pg/g bw gained (wet wt) | pg TCDD equivalents accumulated per gram of body weight gained from egg to largest chick stage | Not Reported | Nestling | Beaver Islands, Lake Michigan | 20 chicks | 5.8 pg TCDD equivalents/g fish, wet wt | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets | |
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | 37.6 pg/g bw gained (wet wt) | pg TCDD equivalents accumulated per gram of body weight gained (from eggs to largest chicks) | Not Reported | Nestling | Thunder Bay, Lake Huron | 20 chicks | 18.1 pg TCDD equivalents/g fish, wet wt | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets | |
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | 28.3 pg/g bw gained (wet wt) | pg TCDD equivalents accumulated per gram of body weight gained (from eggs to largest chicks) | Not Reported | Nestling | North Channel, Lake Huron | 20 chicks | 7.6 pg TCDD equivalents/g fish, wet wt | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets | |
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | 47.5 pg/g bw gained (wet wt) | pg TCDD equivalents accumulated per gram of body weight gained (from eggs to largest chicks) | Not Reported | Nestling | St. Martin's Shoal, Lake Huron | 20 chicks | 11.1 pg TCDD equivalents/g fish, wet wt | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CARBARYL | increased at 0.56 kg/ha (2, 8-9 d. post-spray) | whole carcass concentration of carbaryl | Not Reported | Not Reported | 8-9 birds/group | 0, 0.44, 0.56 kg/ha application | TOX-EXP IND - accumulation | 2, 8-9, 21-30 d. post-spray | field application | Toxicity Factor Datasets |
CARBARYL | no effect | whole carcass lipid content | Not Reported | Not Reported | 6-13 birds/group | 0, 0.44, 0.56 kg/ha application | TOX-Non-Repro-Sublethal - whole animal | 2, 8-9, 21-30 d. post-spray | field application | Toxicity Factor Datasets |
CARBARYL | no effect | brain acetylcholinesterase activity | Not Reported | Not Reported | 6-13 birds/group | 0, 0.44, 0.56 kg/ha application | TOX-EXP IND - biomarkers | 2, 8-9, 21-30 d. post-spray | field application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no correlation with DDE residues in eggs | eggshell thickness | Female | Adult | McHenry and Billings Counties | 12 eggs | 0.57 ppm DDE in eggs | TOX-REPRO - physiology | NR | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | significantly decreased compared to pre-1943 samples | eggshell thickness (of intact or broken eggshells) | Female | Adult | Anacapa Island and Isla Coronado Norte | 86 eggs | 0.03 ppm DDT plus TDE, 0.12 ppm DDE, wet wt in anchovies | TOX-REPRO - physiology | NR | diet | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | increased compared to positive control (1969 data) | mean number of fledglings produced per nest in 1974 | Both Male and Female | Fledgling | Anacapa Island and Isla Coronado Norte | 1286 nests | 0.03 ppm DDT plus TDE, 0.12 ppm DDE, wet wt in anchovies | TOX-REPRO - reproductive success | NR | diet | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | non-detectable DDT plus TDE, 96.6 ppm DDE, lipid wet basis | concentration in egg contents | Female | Adult | Anacapa Island and Isla Coronado Norte | 39 eggs | 0.03 ppm DDT plus TDE, 0.12 ppm DDE, wet wt in anchovies | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
AROCLOR 1254, DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN | 0.896 ppm DDE, 0.256 ppm DDD, 0.166 ppm DDT, 0.208 dieldrin, 2.241 ppm PCB 1254 | mean residues in eggs | Female | Adult | east coast | 29 eggs | 0.017 ppm DDE, 0.016 ppm DDD, 0.020 ppm DDT, 0.005 ppm dieldrin, 0.196 ppm PCB 1254, wet wt | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 8 ug/g | critical threshold of DDE concentration in egg (wet wt basis) associated with 20% eggshell thinning | Both Male and Female | Embryo | 813 eggs | ND-100 ug/g in eggs | TOX-REPRO - physiology | NR | diet | Toxicity Factor Datasets |
DDE (4,4'-) | 3 ug/g | lowest level of DDE that would result in severely lowered reproductive success | Both Male and Female | Embryo | 156 eggs | ND-9 ug/g in eggs | TOX-REPRO - reproductive success | NR | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 3 ug/g | level in eggs associated with impaired reproductive success (successful nests fledged at least one chick) | Both Male and Female | Juvenile | 156 eggs | 0.36-8.60 ppm, wet wt in eggs | TOX-REPRO - reproductive success | NR | in ovo | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
FUEL OILS | decrease | hatching success (proportion of eggs hatched per clutch) of oiled versus control eggs | Not Reported | Embryo | Cape Fear River | 61-205 eggs | oil spill | TOX-REPRO - reproductive success | NR | egg surface | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-) | decreased compared with pre-1940 eggs | eggshell thickness index (Ratcliffe's Index) | Not Reported | Embryo | Bear River Migratory Bird Refuge | 93 eggs | 6.6 ppm DDE, 1.3 ppm DDD in eggs, wet wt | TOX-REPRO - physiology | NR | in ovo | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 12.8 ppm DDE, 0.8 ppm DDD, wet wt | mean concentration in breast muscle | Not Reported | Adult | Bear River Migratory Bird Refuge | 24 birds | 0.01-0.02 ppm DDE in fish | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
DDE (4,4'-) | 61.5 ppm DDE, 5.2 ppm DDD, wet wt | mean concentration in visceral fat | Not Reported | Adult | Bear River Migratory Bird Refuge | 18 birds | 0.01-0.02 ppm DDE in fish | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
DDE (4,4'-) | 0.55 ppm DDE, 0.07 ppm DDD, wet wt | mean concentration in blood | Not Reported | Adult | Bear River Migratory Bird Refuge | 16 birds | 0.01-0.02 ppm DDE in fish | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
DDE (4,4'-) | 6.6 ppm DDE, 1.3 ppm DDD, wet wt | mean concentration in whole eggs | Not Reported | Embryo | 40 eggs | 0.01-0.02 ppm DDE in fish | TOX-EXP IND - accumulation | NR | diet (parental) | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), POLYCHLORINATED BIPHENYLS | no effect | eggshell thickness compared with pre-1947 measurements | Not Reported | Embryo | Tule Lake National Wildlife Refuge | 29 eggs | 1.4 ppm DDE, 0.18 ppm DDT+DDD, 2.21 ppm PCBs in eggs | TOX-REPRO - physiology | NR | in ovo | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
CHLORDANE, DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR, MERCURY (elemental), POLYCHLORINATED BIPHENYLS, SELENIUM (elemental) | no effect | eggshell thickness compared to those of museum eggs from 1907 and 1936 | Female | Adult | North and South San Francisco Bay | 29 eggs | 0.03-0.17 (oxychlordanes), 0.11-0.58 (trans-nonachlor), 0.81-2.86 (PCB), 0.05-0.26 (cis-chlordane), 0.28-0.84 (DDE), 0.02-0.15 (DDD), <0.01-0.15 (DDT), 0.08-0.19 (dieldrin), <0.01-0.14 (heptachlor epoxide), <0.01-0.15 (cis-nonachlor), 0.55-0.72 (mercury), | TOX-REPRO - physiology | NR | diet (parent) | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIAZINON | decreased (84%) | percent inhibition of post-mortem brain cholinesterase activity compared to control | Not Reported | Juvenile | 5 ducks | 183 ug/g ingesta | TOX-EXP IND - biomarkers | NR | diet | Toxicity Factor Datasets |
BENDIOCARB | decreased (73%) | percent inhibition of post-mortem brain cholinesterase activity compared to control | Not Reported | Adult | 4 ducks | 1.17 ug/g ingesta | TOX-EXP IND - biomarkers | NR | diet | Toxicity Factor Datasets |