Species
Filter by Species
Filter by Toxicity Endpoint Type
Filter by Exposure Endpoint Type
Filter by Chemical
Filter by Location
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CHLOROPHACINONE | 99 ug | total carcass residues 28 d after removal from treatment | Not Reported | Adult | 1 owl | 3.2 ppm in voles maintained on treated food | TOX-EXP IND - accumulation | 6 d | diet | Toxicity Factor Datasets |
CHLOROPHACINONE | no effect | occurence of external bleeding or internal abnormalities after removal from treated diet | Not Reported | Adult | 1 owl | 3.2 ppm in voles maintained on treated food | TOX-Non-Repro-Sublethal - whole animal | 6 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIPHACINONE | 4.1-5.5 mg | doses resulting in symptoms and death in 2/3 birds within 14 days | Not Reported | Adult | 3 owls | 4.1-5.5 mg total consumed in mice fed a 0.01% bait | TOX-MORT - toxicity benchmarks | 5 days | diet | Toxicity Factor Datasets |
DIPHACINONE | increased | time to coagulation in blood sampled 3 days after treatment ended | Not Reported | Adult | 3 owls | 4.1-5.5 mg total consumed in mice fed a 0.01% bait | TOX-Non-Repro-Sublethal - organ/system effects | 5 days | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
STRYCHNINE | increased | occurence (compared with pre-dose values) of uncoordinated movement, tremors, loss of perching ability and ability to stand on the ground | Not Reported | Adult | 1 bird | 1.8 mg injected into mouse | TOX-Non-Repro-Sublethal - behavioral effects | single exposure | diet | Toxicity Factor Datasets |
STRYCHNINE | increased | occurence (compared with pre-dose values) of uncoordinated movement, tremors, loss of perching ability and ability to stand on the ground | Not Reported | Adult | 1 bird | 1.0 mg injected into mouse | TOX-Non-Repro-Sublethal - behavioral effects | single exposure | diet | Toxicity Factor Datasets |
STRYCHNINE | increased | occurence of errors (compared with pre-test values) in a reversal learning test | Not Reported | Adult | 1 bird | 0.4 mg injected into mouse | TOX-Non-Repro-Sublethal - behavioral effects | single exposure | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | 293.43-820.93 ppm, lipid weight | concentrations of DDT, DDE, DDD (combined) in skin and brains, 2 years post-application | Not Reported | Not Reported | 3.2 km NE of Davis | 2 birds | 0.22 kg DDT/ha | TOX-EXP IND - accumulation | 1 application | experimental application | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-) | see figure | figure showing concentration of DDT and metabolites in skin and brains before and after application | Not Reported | Not Reported | 3.2 km NE of Davis | 27 birds (3-4/sampling time) | 0.22 kg DDT/ha | TOX-EXP IND - accumulation | 1 application | experimental application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DIELDRIN | increased at 1 mg/kg | latency to formation of natural prey killing behaviors | Not Reported | Juvenile | collected in San Diego County, CA | 10-11/dose | 0, 1 mg/kg bw/d (87% active ingredient) | TOX-Non-Repro-Sublethal - behavioral effects | until death (max. 103 d) | gavage | Toxicity Factor Datasets |
DIELDRIN | increased at 1, 2, 4, 8 mg/kg/d | rate of mortality compared with controls | Not Reported | Juvenile | collected in San Diego County, CA | 10-11/dose | 0, 1, 2, 4, 8 mg/kg bw/d (87% active ingredient) | TOX-MORT - dose-response data | until death (max. 103 d) | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 3.09 (0.09 SE) ppm, wet wt | concentration in eggs | Not Reported | Embryo | southern IL | 20 clutches, 104 eggs | 21.04 (3.51 SE) ppm in fat of adult females | TOX-EXP IND - accumulation | NR | parental transfer | Toxicity Factor Datasets |
DDE (4,4'-) | decreased | eggshell thickness index compared with reference samples collected in 1875-95 | Not Reported | Embryo | southern IL | 20 clutches, 104 eggs | 21.04 (3.51 SE) ppm in fat of adult females | TOX-REPRO - physiology | NR | parental transfer | Toxicity Factor Datasets |
DDE (4,4'-) | y = 92.610 - 2.412 log x | linear negative correlation of egg DDE concentration and shell thickness | Not Reported | Embryo | southern IL | 20 clutches, 104 eggs | 21.04 (3.51 SE) ppm in fat of adult females | TOX-REPRO - physiology | NR | parental transfer | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-), POLYCHLORINATED BIPHENYLS | 7% decrease | eggshell thickness compared with pre-1947 reference eggs | Female | Adult | Cape Romain National Wildlife Refuge | 20 eggs | 0.48 ug/g, wet wt, DDE; 1.08 ug/g, wet wt, PCBs in eggs | TOX-REPRO - physiology | NR | site contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Toxicity Endpoint Type | Type |
---|---|---|---|
POLYCHLORINATED BIPHENYLS | review | TOX-Non-Repro-Sublethal - cellular/biochemical effects | Toxicity Factor Datasets |
POLYCHLORINATED BIPHENYLS | review | TOX-MORT - toxicity benchmarks | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
POLYCHLORINATED BIPHENYLS | see figures | figure for each dose, showing metabolic rate at increasing ambient temperatures | Not Reported | Adult | 10 birds/group | 0, 1, 3, 9 ppm (dry wt) in food | TOX-Non-Repro-Sublethal - organ/system effects | 10 wks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LINDANE | 18-21% decrease @ 20 mg/kg 7x or 3x/wk | eggshell thickness, compared to control | Female | Adult | 5/dose | control, 20 mg/kg given 7x, 3x or 2x/wk | TOX-REPRO - physiology | 8 wks | gavage | Toxicity Factor Datasets |
LINDANE | decrease @ 20 mg/kg 7x or 3x/wk | calcium concentration in plasma and shell gland mucosa and density and size of eggshell pores | Female | Adult | 5/dose | control, 20 mg/kg given 7x, 3x or 2x/wk | TOX-REPRO - physiology | 8 wks | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|
DDT (Technical Grade Mixture) | increase @ 0.05 - 0.4% in diet | Not Reported | Not Reported | 4/dose | 0, 0.025, 0.05, 0.1, 0.2, 0.4% | TOX-MORT - dose-response data | 30 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDT (Technical Grade Mixture) | no effect | fertility, hatchability and duckling weight | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-REPRO - reproductive success | 343 d | diet | Toxicity Factor Datasets |
DDT (4,4'-) | no effect | fertility, hatchability and duckling weight | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-REPRO - reproductive success | 343 d | diet | Toxicity Factor Datasets |
DIELDRIN | no effect | fertility, hatchability and duckling weight | Female | Adult | 18/dose | 0, 1, 5, 10 mg/kg diet | TOX-REPRO - reproductive success | 343 d | diet | Toxicity Factor Datasets |
DDT (Technical Grade Mixture) | no effect | hepatic microsomal enzyme activity (aniline hydroxylase and aminopyrine N-demethylase) | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 343 d | diet | Toxicity Factor Datasets |
DDT (4,4'-) | no effect | hepatic microsomal enzyme activity (aniline hydroxylase and aminopyrine N-demethylase) | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 343 d | diet | Toxicity Factor Datasets |
DIELDRIN | no effect | hepatic microsomal enzyme activity (aniline hydroxylase and aminopyrine N-demethylase) | Female | Adult | 18/dose | 0, 1, 5, 10 mg/kg diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 343 d | diet | Toxicity Factor Datasets |
DDT (Technical Grade Mixture) | DDT <0.1, DDE 0.2 - 1.2 ug/g dry wt @ 0 ppm; DDT 0.3 - 4.2, DDE 1.0 - 12.7 @ 2 ppm; DDT 1.3 - 25.0, DDE 5.0 - 110.1 @ 20 ppm; DDT 25.5 - 254, DDE 58.0 - 1234 @ 200 ppm | DDT and DDE concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-EXP IND - accumulation | 343 d | diet | Toxicity Factor Datasets |
DDT (4,4'-) | DDT <0.1, DDE 0.2 - 1.2 ug/g dry wt @ 0 ppm; DDT 0.6 - 2.4, DDE 1.2 - 10.1 @ 2 ppm; DDT 2.2 - 29.2, DDE 15.7 - 153.5 @ 20 ppm; DDT 14.9 - 102.0, DDE 45.0 - 187.0 @ 200 ppm | DDT and DDE concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | 0, 2, 20, 200 mg/kg diet | TOX-EXP IND - accumulation | 343 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
TRIETHYLTIN CHLORIDE | decrease @ 50 ppm | body weight, compared to control | Not Reported | Juvenile | 5/dose | control, 0.5, 5.0, 50 ppm (Sn) as triethyltin chloride | TOX-Non-Repro-Sublethal - whole animal | 73 - 75 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | egg production, eggshell thickness and fertility, compared to control | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 4 ppm | TOX-REPRO - physiology | 90 d | diet | Toxicity Factor Datasets |
DIELDRIN | decrease | average % hatchability, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 4 ppm | TOX-REPRO - reproductive success | 90 d | diet | Toxicity Factor Datasets |
DIELDRIN | no effect | progeny growth (average body weights) at hatch to 6 wks of age | Both Male and Female | Juvenile | 5 trios (2F, 1M adults)/dose | control, 4 ppm | TOX-REPRO - development | 90 d | diet | Toxicity Factor Datasets |
PARATHION | no effect | egg production and fertility, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 10 ppm | TOX-REPRO - physiology | 90 d | diet | Toxicity Factor Datasets |
PARATHION | no effect | % hatchability, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 10 ppm | TOX-REPRO - reproductive success | 90 d | diet | Toxicity Factor Datasets |
PARATHION | decrease | eggshell thickness, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | control, 10 ppm | TOX-REPRO - physiology | 90 d | diet | Toxicity Factor Datasets |
PARATHION | no effect | progeny growth (average body weights) at hatch to 6 wks of age | Both Male and Female | Juvenile | 5 trios (2F, 1M adults)/dose | control, 10 ppm | TOX-REPRO - development | 90 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
RADIONUCLIDES | see citation | table of mean concentrations of 6 radionuclides (238Pu, 239Pu, 241Am, 242Cm, 244Cm, 90Sr) in 6 mallard tissue types | Not Reported | Adult | leaching ponds, Test Reactor Area, Idaho National Engineering Laboratory | 7-15 | see citation for table radionuclide concentrations in water, plankton, periphyton, sediment | TOX-EXP IND - accumulation | 43-145 d | site contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | 5.7 ppm (whole blood); 6.2 ppm (liver); 2.4 ppm (spleen) @ 300 mg/kg body weight | lead concentrations in tissues, 96 hr after exposure to lead in ducklings receiving vitamin E | Not Reported | Juvenile | 5/dose | control, 300 mg/kg body weight; elemental lead packaged in gelatin capsules | TOX-EXP IND - accumulation | single | oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENIUM COMPOUNDS, SELENOMETHIONINE | increase @ 15, 30 ppm | plasma and liver GSH-peroxidase activity (for all Se forms), compared to controls | Not Reported | Juvenile | 10/dose | control, 15, 30 ppm Se as seleno-D,L-methionine, seleno-L-methionine or selenized yeast | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 2 wks | diet | Toxicity Factor Datasets |