DIELDRIN
Mallard duck (Anas platyrhynchos)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 16.4 ug/g diet | 24-d LOAEL based on growth impairment | Not Reported | Juvenile | 10/dose | Toxicity Factor Datasets | 1 - 25 d | Laboratory | |
DIELDRIN | 0.3 ug/g | 24-d NOAEL based on growth impairment | Not Reported | Juvenile | 10/dose | Toxicity Factor Datasets | 1 - 25 d | Laboratory | |
DIELDRIN | see citation | figures of tissue dieldrin concentrations at different exposure times and doses | Not Reported | Juvenile | 10/dose | Toxicity Factor Datasets | 1 - 25 d | Laboratory | |
DIELDRIN | no effect | body weight at end of experiment | Not Reported | Juvenile | 12/dose | Toxicity Factor Datasets | 1 d at initiation | Laboratory | |
DIELDRIN | no effect | no mortality observed | Not Reported | Juvenile | 12/dose | Toxicity Factor Datasets | 1 d at initiation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | increased @ 10 ppm (liver only), 30 ppm (brain only) | brain and liver weight to body weight ratios versus controls | Both Male and Female | Juvenile | 9-25 per group | Toxicity Factor Datasets | 75 days | Laboratory | |
DIELDRIN | increased@ 4, 10, 30 ppm | hepatic microsomal enzyme activity versus controls | Both Male and Female | Juvenile | 5-15 per group | Toxicity Factor Datasets | 75 days | Laboratory | |
DIELDRIN | increased @ 30 ppm | liver protein concentration versus controls | Both Male and Female | Juvenile | 5-15 per group | Toxicity Factor Datasets | 75 days | Laboratory | |
DIELDRIN | increased @ 10, 30 ppm | liver DNA content versus controls | Male | Both Adults and Juveniles | 5-15 per group | Toxicity Factor Datasets | 75 days | Laboratory | |
DIELDRIN | decreased @ all doses | % drake encounter scores | Male | Both Adults and Juveniles | 30 per group | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | egg production, eggshell thickness and fertility, compared to control | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | Toxicity Factor Datasets | Laboratory | |
DIELDRIN | decrease | average % hatchability, compared to controls | Both Male and Female | Adult | 5 trios (2F, 1M)/dose | Toxicity Factor Datasets | Laboratory | |
DIELDRIN | no effect | progeny growth (average body weights) at hatch to 6 wks of age | Both Male and Female | Juvenile | 5 trios (2F, 1M adults)/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | 0.3 ug/g dry wt. @ 0 ppm; 0.9 - 5.0 @ 1 ppm; 4.1 - 40.1 @ 5ppm; 6.1 - 78.5 @ 10 ppm | dieldrin concentrations in egg dry matter ranging from 0-14 d to 330 - 343 d sampling periods at 4 dietary doses | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DIELDRIN | 6% decrease @ 10 ppm | eggshell thickness | Female | Adult | 18/dose | Toxicity Factor Datasets | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | increase @ 10-20 ug/g | estradiol metabolism and cytochrome P450 concentration | Female | Adult | 4/dose/sampling time | Toxicity Factor Datasets | 90 d at initiation | Laboratory | |
DIELDRIN | no effect | body or liver weight at end of experiment | Female | Adult | 4/dose/sampling time | Toxicity Factor Datasets | 90 d at initiation | Laboratory |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 155.8 (coeff. of variation = 16.0%) | 5 day dietary LC50 | Not Reported | Juvenile | 8-10/dose | Toxicity Factor Datasets | 5 days | Laboratory |
Peregrine Falcon (Falco peregrinus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DIELDRIN | review | mortality in conjunction with pesticide use and residues in birds | Not Reported | Adult | Not Reported | Toxicity Factor Datasets | CANADA, UNITED KINGDOM, USA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, POLYCHLORINATED BIPHENYLS | 8.31 (1.67-45.63; PCBs); 4.45 (0.76-28.05; DDE); 0.36 (0.05-1.80; dieldrin) | geometric mean (range) residues in eggs, ppm, wet wt | Female | Adult | 20 eggs | Rankin Inlet | Toxicity Factor Datasets |
DDE (4,4'-), DIELDRIN, POLYCHLORINATED BIPHENYLS | 15% | percent eggshell thinning compared with pre-DDT reference eggs | Female | Adult | 20 eggs | Rankin Inlet | Toxicity Factor Datasets |
DDE (4,4'-), DIELDRIN, POLYCHLORINATED BIPHENYLS | 0.12 (0-2.59; PCBs); 0.06 (0-2.70; DDE); ND (0-0.06; dieldrin) | geometric mean residues (range) in plasma, ppm, wet wt of nestlings | Not Reported | Juvenile | 79 nestlings | Rankin Inlet | Toxicity Factor Datasets |
DDE (4,4'-), DIELDRIN, POLYCHLORINATED BIPHENYLS | males: 0.15 (0-3.27; PCBs); 0.31 (0.05-1.95; DDE); 0.03 (0-0.30; dieldrin) females: 0.87 (0-6.82; PCBs); 0.63 (0-4.23; DDE); 0.04 (0-0.37; dieldrin) |
geometric mean residues (range) in plasma, ppm, wet wt of adult birds | Both Male and Female | Adult | 26 males, 34 females | Rankin Inlet | Toxicity Factor Datasets |
DDE (4,4'-), DIELDRIN, POLYCHLORINATED BIPHENYLS | liver: 1.58-59.45, PCBs; 0.99-18.84, DDE; 0.06-0.79, dieldrin breast: 0.35-57.30, PCBs; 0.30-16.95, DDE; 0-0.19, dieldrin |
range of residues in liver and breast muscle (ppm, wet wt) of 22-31 day old nestlings found dead | Not Reported | Juvenile | 7 birds | Rankin Inlet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries |
---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE | no effect | number of viable eggs or young versus "normal" nest success | Not Reported | Juvenile | 15 nests | Peace, Slave, and Mackenzie Rivers | Toxicity Factor Datasets | CANADA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, POLYCHLORINATED BIPHENYLS | 15.8% | mean eggshell thinning compared to "pre-pesticide" reference eggs | Female | Adult | 78 eggs | Rankin Inlet | Toxicity Factor Datasets |
Double-crested Cormorant (Phalacrocorax auritus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, HEXACHLOROBENZENE, MERCURY COMPOUNDS, POLYCHLORINATED BIPHENYLS | 23.9% thinner | eggshell thickness compared with pre-1947 eggshells in contaminated colonies | Not Reported | Embryo | 18 eggs | Lake Huron | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, HEXACHLOROBENZENE, MERCURY COMPOUNDS, POLYCHLORINATED BIPHENYLS | 2.4% | mean hatching success in contaminated colonies | Not Reported | Embryo | 331 eggs | Lake Huron | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, HEXACHLOROBENZENE, MERCURY COMPOUNDS, POLYCHLORINATED BIPHENYLS | 0.06-0.11 (1972); 0.3 (1973) | fledging success (young/nest) in contaminated colonies | Not Reported | Embryo | 42 (1973)-66 (1972) nests | Lake Huron | Toxicity Factor Datasets |
Bullfrog (Lithobates catesbeianus formerly Rana catesbeiana)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
---|---|---|---|---|---|---|---|---|---|
DIELDRIN | 5.1 ug/g at 8.7 ug/l | whole body dieldrin concentration (ug/g, wet wt.) at the LC50 | Not Reported | Tadpole | Not Reported | Toxicity Factor Datasets | 50 d | Laboratory | |
DIELDRIN | 6.0 ug/g at 11.2 ug/l | whole body dieldrin concentration (ug/g, wet wt.) | Not Reported | Tadpole | Not Reported | Toxicity Factor Datasets | 50 d | Laboratory | |
DIELDRIN | 2.0 ug/g at 4.0 ug/l | whole body dieldrin concentration (ug/g, wet wt.) | Not Reported | Tadpole | Not Reported | Toxicity Factor Datasets | 50 d | Laboratory | |
DIELDRIN | 360 - 540 | range of bioconcentration factors; calculated by dividing the whole body tissue dieldrin concentration by water dieldrin concentration | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | Toxicity Factor Datasets | 50 d | Laboratory | |
DIELDRIN | 36,000 - 54,000 | range of lipid bioconcentration factors; calculated by dividing the whole body bioconcentration values x 100 by percent lipid | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | Toxicity Factor Datasets | 50 d | Laboratory | |
DIELDRIN | 30.3 ug/l (95% CL: 26.2 - 35.2 ug/l) | LC50 | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | Toxicity Factor Datasets | 29 d | Laboratory | |
DIELDRIN | 52.3 ug/l | LOAEL | Not Reported | Tadpole | 20 animals/replicate; 4 replicates/dose | Toxicity Factor Datasets | 29 d | Laboratory |
American Kestrel (Falco sparverius)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
---|---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | 10.4 (0.6 SE) ppm (wet wt) | DDE concentration in brain | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory | |
DDE (4,4'-), DIELDRIN, LEAD COMPOUNDS | decreased | bw (versus pre-study bw) | Female | Juvenile | 2 | Toxicity Factor Datasets | Laboratory |
Deer Mouse (Peromyscus maniculatus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DIELDRIN | decrease at 5 mg/kg | homing orientation test, measured as time in maze pointing to capture site | Both Male and Female | Both Adults and Juveniles | 15 animals/dose | NR | Toxicity Factor Datasets |
DIELDRIN | decrease at 5 mg/kg | homing, measured as number recaptured at pre-exposure site | Both Male and Female | Both Adults and Juveniles | 15 animals/dose | NR | Toxicity Factor Datasets |
Great Horned Owl (Bubo virginianus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Type | Countries |
---|---|---|---|---|---|---|---|
ALDRIN, BRODIFACOUM, CARBOFURAN, CHLORDANE, DIELDRIN, ENDRIN, FAMPHUR, FENTHION, PHORATE, STRYCHNINE | review | summaries of mortality due to organochlorine, anticholinesterase, anticoagulant, strychnine pesticides | Not Reported | Not Reported | Toxicity Factor Datasets | CANADA, USA |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DIELDRIN | no effect | productivity in contaminated versus uncontaminated sites | Both Male and Female | Adult | 3-4 nests on contaminated sites; 5-9 nests on uncontaminated sites | Rocky Mountain Arsenal National Wildlife Refuge | Toxicity Factor Datasets |
DIELDRIN | negative correlation | relationship between residue in plasma and survival | Not Reported | Juvenile | 6 birds (contaminated sites), 10 birds (uncontaminated sites) | Rocky Mountain Arsenal National Wildlife Refuge | Toxicity Factor Datasets |
DIELDRIN | no effect | daily and interval survival estimates on uncontaminated versus contaminated sites | Not Reported | Juvenile | 14 birds on contaminated sites; 41 birds on uncontaminated sites | Rocky Mountain Arsenal National Wildlife Refuge | Toxicity Factor Datasets |
DIELDRIN | no effect | daily survival rates on uncontaminated versus contaminated sites | Not Reported | Adult | 9 birds on contaminated sites; 11 birds on uncontaminated sites | Rocky Mountain Arsenal National Wildlife Refuge | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE | no effect | eggshell thickness compared to pre-1946 museum speciments | Female | Adult | 3 eggs | south-central Montana | Toxicity Factor Datasets |
Brown Pelican (Pelecanus occidentalis)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
AROCLOR 1254, DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN | 0.896 ppm DDE, 0.256 ppm DDD, 0.166 ppm DDT, 0.208 dieldrin, 2.241 ppm PCB 1254 | mean residues in eggs | Female | Adult | 29 eggs | east coast | Toxicity Factor Datasets |
California Clapper Rail (Rallus longirostris ssp. obsoletus)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
CHLORDANE, DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR, MERCURY (elemental), POLYCHLORINATED BIPHENYLS, SELENIUM (elemental) | no effect | eggshell thickness compared to those of museum eggs from 1907 and 1936 | Female | Adult | 29 eggs | North and South San Francisco Bay | Toxicity Factor Datasets |
Mourning Dove (Zenaida macroura)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
ALDRIN, DIELDRIN | <0.1 ppm aldrin, 3.8 ppm dieldrin, 0.3 ppm DDT and metabolites, wet wt | post-mortem whole body concentrations | Not Reported | Not Reported | 1 bird | Toxicity Factor Datasets |
Great Horned Owl (Bubo virginianus), Mourning Dove (Zenaida macroura)
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
---|---|---|---|---|---|---|---|
ALDRIN, DIELDRIN | 6.1 ppm (brain), 10.7 ppm (body remainder) dieldrin, wet wt | post-mortem concentrations | Not Reported | Not Reported | 1 bird | Toxicity Factor Datasets |